Pain, PostoperativeNCT06664177
Analgesic Efficacy of Quadratus Lumborum vs. Transversalis Fascia Block in Inguinal Hernia Surgery
A study testing Transversalis Fascia Plane Block and Anterior Quadratus Lumborum Block (QLB) in people with Pain, Postoperative, run by Gaziosmanpasa Research and Education Hospital at 1 site in Turkey (Türkiye).
Trial summary
It is planned to compare the postoperative analgesic efficacy of the Transversalis Fascia Plane Block and the anterior Quadratus Lumborum Block in elective inguinal hernia surgeries. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Pain, Postoperative
- What is being tested?
- Transversalis Fascia Plane Block and Anterior Quadratus Lumborum Block (QLB)
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Nov 2024to 10 Sep 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Ages 18-65
- ASA Classification 1-2
Who cannot join
- Allergy to local anesthetics
- Presence of infection at the procedure site
- BMI > 35 kg/m²
- Bleeding disorders or anticoagulant use
- Chronic analgesic or opioid use
- Mental or psychiatric disorders
- ASA Classification 3-4 patients(Severe COPD, history of cerebrovascular events, liver and kidney disease will be excluded from the study.)
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Gaziosmanpasa Research and Training Hospital
Istanbul, 34255
serpil sehirlioglu, MD, 05054431852, drserpilsahin@gmail.com
About this study
Official title: Comparison of the Postoperative Analgesic Efficacy of Quadratus Lumborum Block and Transversalis Fascia Block in Inguinal Hernia Surgery
It is planned to compare the postoperative analgesic efficacy of the Transversalis Fascia Plane Block and the anterior Quadratus Lumborum Block in elective inguinal hernia surgeries.
Read the detailed description
It is planned to compare the postoperative analgesic efficacy of the Transversalis Fascia Plane Block and the anterior Quadratus Lumborum Block in elective open inguinal hernia surgeries.
Primary Objective: Our primary aim is to compare and evaluate the time to first rescue analgesic requirement after the application of anterior Quadratus Lumborum Block and Transversalis Fascia Plane Block in patients undergoing elective open inguinal hernia surgeries under spinal anesthesia.
Secondary Objectives:
To compare the total analgesic consumption in the first 24 hours postoperatively.
To compare the Numeric Rating Scale (NRS) values (at rest and dynamic) of patients at postoperative follow-ups at 2, 4, 8, 12, and 24 hours.
To compare postoperative side effects such as nausea and vomiting. In trunk blocks, local anesthetic is applied to the interfascial area between the anterior abdominal wall or back muscles. Due to the lack of blood circulation and vascularization in the interfascial area, the absorption of local anesthetics is slow, allowing for prolonged analgesic effects. For this reason, trunk blocks are used as part of multimodal analgesia. The effectiveness of trunk blocks can vary based on the patient's structural anatomical differences and previous surgeries, but an average analgesic effect of 8-12 hours is typically observed. Sometimes, analgesic effects have been reported to last up to 24 hours.
Pain that arises from elective laparoscopic inguinal hernia surgeries can negatively impact postoperative immobilization, atelectasis, pneumonia due to atelectasis, and prolonged hospital stays. Due to the side effects associated with opioid medications used for postoperative analgesia, such as nausea, vomiting, itching, constipation, and dependency, non-opioid analgesic medications and regional techniques are used as part of multimodal analgesia to reduce opioid use.
Quadratus Lumborum and Transversalis Fascia Blocks can be safely and easily performed, especially in lower abdominal surgery, due to advancements in trunk blocks and ultrasound technology in recent years.
This study aims to evaluate the postoperative analgesic efficacy of Quadratus Lumborum Blocks and Transversalis Fascia Blocks administered to patients undergoing elective inguinal hernia surgery. The Transversalis Fascia Block can be utilized in lower abdominal surgeries by blocking the ilioinguinal, iliohypogastric nerves, and the T12 intercostal nerve. The Quadratus Lumborum Block provides analgesic efficacy in the T7-L2 dermatomal area.In patients planned for elective laparoscopic inguinal hernia surgery, informed consent was obtained after detailed information was provided. The patients were randomly divided into two groups using closed envelope randomization: the anterior Quadratus Lumborum Block group and the Transversalis Fascia Block group.
All patients will be taken to the block room after the surgery. All blocks will be performed under ultrasound guidance by the same anesthesia specialist while the patients are in the lateral decubitus position, with the surgical sites facing up.
In the Quadratus Lumborum block group, in the lateral decubitus position, a convex ultrasound probe will be sterilely placed in the subcostal area and above the iliac crest. The quadratus lumborum and psoas major muscles, as well as the L4 vertebra's transverse process, will be visualized. Using the in-plane technique and a 22G 100 mm peripheral block needle, the placement will first be identified through hydrodissection in the subfascial area between the quadratus lumborum and psoas major muscles. After localization, 20 mL of 0.5% bupivacaine will be injected slowly, aspirating every 5 cc, while visualizing the local anesthetic pushing the fascia in the ultrasound image.
In the Transversalis Fascia Block group, the same procedure will be followed as in the Quadratus Lumborum block group, with the ultrasound probe being placed in the same location, and the same in-plane technique will be applied with a 22G 100 mm peripheral block needle. After hydrodissection, 20 mL of 0.5% bupivacaine will be injected slowly in the same manner.
All patients will be monitored for 30 minutes in the block room after the block application.
All patients will receive anesthesia using the same technique under spinal anesthesia with bupivacain 12 mg intratechal space before surgery. At the end of the operation, all patients will receive intravenous 1g of paracetamol for postoperative analgesia. Routine extubation will be performed, and patients will be sent to the ward after recovery.
Postoperative analgesia for patients was planned as paracetamol 4x1g. Patients will be followed up by a different blinded anesthesia assistant from the one who performed the block at 2, 4, 8, 12, and 24 hours. The first rescue analgesia times, NRS scores (evaluated on a scale of 1 to 10, where 0 means no pain and 10 means very severe pain), postoperative side effects, and total analgesic amounts used in 24 hours will be recorded.
In postoperative follow-ups, for patients with NRS scores greater than 3, intravenous ibuprofen will be planned as rescue analgesia in the ward. If pain does not resolve within 30 minutes, dexketoprophen 50 mg IV will be planned.
In trunk blocks, blocking the thoracoabdominal nerves that travel between the fascia with local anesthetics is thought to provide analgesia during the postoperative period, increasing patient comfort, reducing postoperative opioid consumption and dependency, facilitating early mobilization, shortening the hospital stay, and minimizing opioid side effects.
- Conditions
- Pain, Postoperative
- Being tested
- Transversalis Fascia Plane Block, Anterior Quadratus Lumborum Block (QLB)
- Keywords
- quadratus lumborum block, Transversalis Fascia Plane Block, inguinal hernia
- Medical subject headings
- Pain, Postoperative, Hernia, Inguinal
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Transversalis Fascia Plane BlockProcedure or surgery
In the Transversalis Fascia Block group, the same procedure will be followed as in the Quadratus Lumborum block group, with the ultrasound probe being placed in the same location, and the same in-plane technique will be applied using a 22G, 100 mm peripheral block needle. The needle tip will be advanced through the posterior aponeurotic extension (tail) of the transversus abdominis muscle to the transversalis fascia plane, immediately superficial to the perinephric fat. After hydrodissection confirms correct needle placement, 20 mL of 0.25% bupivacaine will be injected slowly.
Anterior Quadratus Lumborum Block (QLB)Procedure or surgery
In the Quadratus Lumborum block group, in the lateral decubitus position, a convex ultrasound probe will be sterilely placed in the subcostal area and above the iliac crest. The quadratus lumborum and psoas major muscles, as well as the L4 vertebra's transverse process, will be visualized. Using the in-plane technique and a 22G 100 mm peripheral block needle, the placement will first be identified through hydrodissection in the subfascial area between the quadratus lumborum and psoas major muscles. After localization, 20 mL of 0.25% bupivacaine will be injected slowly, aspirating every 5 cc, while visualizing the local anesthetic pushing the fascia in the ultrasound image.
| Study group | Role | What they receive |
|---|---|---|
| anterior quadratus lumborum block | Active comparator | The anterior QLB block will be applied on the operative side Receives: Procedure: Anterior Quadratus Lumborum Block (QLB) |
| transversalis fascia group | Active comparator | the Transversalis Fascia Block will be applied on the operative side Receives: Procedure: Transversalis Fascia Plane Block |
What is being measured
The primary outcome is the main question the study is designed to answer.
time to first rescue analgesic requirement.
Our primary aim is to compare and evaluate the time to first rescue analgesic requirement after the application of anterior Quadratus Lumborum Block and Transversalis Fascia Plane Block in patients undergoing elective inguinal hernia surgeries under spinal anesthesia.
Measured: 24 hour
Secondary outcomes (2)
Total Opioid Consumption
To compare the total analgesic consumption in the first 24 hours postoperatively.
Measured: 24 hour
To compare the NRS (Numering rating scale) values (resting and dynamic) at 2. 4. 8. 12 . 24. hours in the postoperative follow-up of the patients
Assessed at various time points to quantify pain intensity at rest and during movement. The Numerical Rating Scale (NRS) is a pain assessment tool where patients rate their pain from 0 (no pain) to 10 (worst pain).
Measured: 24 hour
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Oct 2024
- Study start1 Nov 2024
- Primary completion1 Sep 2026 (estimated)
- Study completion10 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Pain, PostoperativeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Double blind
- Who is masked
- Investigator, Outcomes assessor
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Gaziosmanpasa Research and Education Hospital
- Sponsor type
- Other government
- Responsible party
- Principal investigator, SERPİL ŞEHİRLİOĞLU, Gaziosmanpasa Research and Education Hospital
- Investigators
- Serpil Sehirlioglu, MD, Principal investigator, Gaziosmanpasa Research and Education Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06664177
- Sponsor's protocol ID
- GaziosmanpasaTREH-FT-İH
- Status last verified
- Jul 2026
- First submitted
- 27 Oct 2024
- Last updated
- 7 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: The data associated with the paper are not publicly available but are available from the corresponding author on reasonable request.
Publications
Abdelbaser I, Mageed NA, El-Emam EM, ALseoudy MM, Elmorsy MM. Preemptive analgesic efficacy of ultrasound-guided transversalis fascia plane block in children undergoing inguinal herniorrhaphy: a randomized, double-blind, controlled study. Korean J Anesthesiol. 2021 Aug;74(4):325-332. doi: 10.4097/kja.20601. Epub 2020 Dec 14.
PubMed 33307633Samerchua A, Leurcharusmee P, Panichpichate K, Bunchungmongkol N, Wanvoharn M, Tepmalai K, Khorana J, Chantakhow S. A Prospective, randomized comparative study between ultrasound-guided posterior quadratus lumborum block and ultrasound-guided ilioinguinal/iliohypogastric nerve block for pediatric inguinal herniotomy. Paediatr Anaesth. 2020 Apr;30(4):498-505. doi: 10.1111/pan.13837. Epub 2020 Feb 21.
PubMed 32030845Ahmed A, Fawzy M, Nasr MAR, Hussam AM, Fouad E, Aboeldahb H, Saad D, Osman S, Fahmy RS, Farid M, Waheb MM. Ultrasound-guided quadratus lumborum block for postoperative pain control in patients undergoing unilateral inguinal hernia repair, a comparative study between two approaches. BMC Anesthesiol. 2019 Oct 17;19(1):184. doi: 10.1186/s12871-019-0862-z.
PubMed 31623572
Study at a glance
From the registry record, last updated by the sponsor on 7 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the Postoperative Analgesic Efficacy of Quadratus Lumborum Block and Transversalis Fascia Block in Inguinal Hernia Surgery
- ClinicalTrials.gov ID
- NCT06664177
- Acronym / sponsor ID
- GaziosmanpasaTREH-FT-İH
- Conditions
- Pain, Postoperative
- Keywords
- quadratus lumborum block, Transversalis Fascia Plane Block, inguinal hernia
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Gaziosmanpasa Research and Education HospitalOther government
- Study start
- 1 Nov 2024 (actual)
- Primary completion
- 1 Sep 2026 (estimated)
- Study completion
- 10 Sep 2026 (estimated)
- First posted
- 29 Oct 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
It is planned to compare the postoperative analgesic efficacy of the Transversalis Fascia Plane Block and the anterior Quadratus Lumborum Block in elective inguinal hernia surgeries.
Detailed description
It is planned to compare the postoperative analgesic efficacy of the Transversalis Fascia Plane Block and the anterior Quadratus Lumborum Block in elective open inguinal hernia surgeries.
Primary Objective: Our primary aim is to compare and evaluate the time to first rescue analgesic requirement after the application of anterior Quadratus Lumborum Block and Transversalis Fascia Plane Block in patients undergoing elective open inguinal hernia surgeries under spinal anesthesia.
Secondary Objectives:
To compare the total analgesic consumption in the first 24 hours postoperatively.
To compare the Numeric Rating Scale (NRS) values (at rest and dynamic) of patients at postoperative follow-ups at 2, 4, 8, 12, and 24 hours.
To compare postoperative side effects such as nausea and vomiting. In trunk blocks, local anesthetic is applied to the interfascial area between the anterior abdominal wall or back muscles. Due to the lack of blood circulation and vascularization in the interfascial area, the absorption of local anesthetics is slow, allowing for prolonged analgesic effects. For this reason, trunk blocks are used as part of multimodal analgesia. The effectiveness of trunk blocks can vary based on the patient's structural anatomical differences and previous surgeries, but an average analgesic effect of 8-12 hours is typically observed. Sometimes, analgesic effects have been reported to last up to 24 hours.
Pain that arises from elective laparoscopic inguinal hernia surgeries can negatively impact postoperative immobilization, atelectasis, pneumonia due to atelectasis, and prolonged hospital stays. Due to the side effects associated with opioid medications used for postoperative analgesia, such as nausea, vomiting, itching, constipation, and dependency, non-opioid analgesic medications and regional techniques are used as part of multimodal analgesia to reduce opioid use.
Quadratus Lumborum and Transversalis Fascia Blocks can be safely and easily performed, especially in lower abdominal surgery, due to advancements in trunk blocks and ultrasound technology in recent years.
This study aims to evaluate the postoperative analgesic efficacy of Quadratus Lumborum Blocks and Transversalis Fascia Blocks administered to patients undergoing elective inguinal hernia surgery. The Transversalis Fascia Block can be utilized in lower abdominal surgeries by blocking the ilioinguinal, iliohypogastric nerves, and the T12 intercostal nerve. The Quadratus Lumborum Block provides analgesic efficacy in the T7-L2 dermatomal area.In patients planned for elective laparoscopic inguinal hernia surgery, informed consent was obtained after detailed information was provided. The patients were randomly divided into two groups using closed envelope randomization: the anterior Quadratus Lumborum Block group and the Transversalis Fascia Block group.
All patients will be taken to the block room after the surgery. All blocks will be performed under ultrasound guidance by the same anesthesia specialist while the patients are in the lateral decubitus position, with the surgical sites facing up.
In the Quadratus Lumborum block group, in the lateral decubitus position, a convex ultrasound probe will be sterilely placed in the subcostal area and above the iliac crest. The quadratus lumborum and psoas major muscles, as well as the L4 vertebra's transverse process, will be visualized. Using the in-plane technique and a 22G 100 mm peripheral block needle, the placement will first be identified through hydrodissection in the subfascial area between the quadratus lumborum and psoas major muscles. After localization, 20 mL of 0.5% bupivacaine will be injected slowly, aspirating every 5 cc, while visualizing the local anesthetic pushing the fascia in the ultrasound image.
In the Transversalis Fascia Block group, the same procedure will be followed as in the Quadratus Lumborum block group, with the ultrasound probe being placed in the same location, and the same in-plane technique will be applied with a 22G 100 mm peripheral block needle. After hydrodissection, 20 mL of 0.5% bupivacaine will be injected slowly in the same manner.
All patients will be monitored for 30 minutes in the block room after the block application.
All patients will receive anesthesia using the same technique under spinal anesthesia with bupivacain 12 mg intratechal space before surgery. At the end of the operation, all patients will receive intravenous 1g of paracetamol for postoperative analgesia. Routine extubation will be performed, and patients will be sent to the ward after recovery.
Postoperative analgesia for patients was planned as paracetamol 4x1g. Patients will be followed up by a different blinded anesthesia assistant from the one who performed the block at 2, 4, 8, 12, and 24 hours. The first rescue analgesia times, NRS scores (evaluated on a scale of 1 to 10, where 0 means no pain and 10 means very severe pain), postoperative side effects, and total analgesic amounts used in 24 hours will be recorded.
In postoperative follow-ups, for patients with NRS scores greater than 3, intravenous ibuprofen will be planned as rescue analgesia in the ward. If pain does not resolve within 30 minutes, dexketoprophen 50 mg IV will be planned.
In trunk blocks, blocking the thoracoabdominal nerves that travel between the fascia with local anesthetics is thought to provide analgesia during the postoperative period, increasing patient comfort, reducing postoperative opioid consumption and dependency, facilitating early mobilization, shortening the hospital stay, and minimizing opioid side effects.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Double blind (investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| anterior quadratus lumborum block | Active comparator | Procedure: Anterior Quadratus Lumborum Block (QLB)The anterior QLB block will be applied on the operative side |
| transversalis fascia group | Active comparator | Procedure: Transversalis Fascia Plane Blockthe Transversalis Fascia Block will be applied on the operative side |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Ages 18-65
- ASA Classification 1-2
Key exclusion criteria (7 listed)
- Allergy to local anesthetics
- Presence of infection at the procedure site
- BMI > 35 kg/m²
- Bleeding disorders or anticoagulant use
- Chronic analgesic or opioid use
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Transversalis Fascia Plane BlockIn the Transversalis Fascia Block group, the same procedure will be followed as in the Quadratus Lumborum block group, with the ultrasound probe being placed in the same location, and the same in-plane technique will be applied using a 22G, 100 mm peripheral block needle. The needle tip will be advanced through the posterior aponeurotic extension (tail) of the transversus abdominis muscle to the transversalis fascia plane, immediately superficial to the perinephric fat. After hydrodissection confirms correct needle placement, 20 mL of 0.25% bupivacaine will be injected slowly. | Procedure or surgery | transversalis fascia group |
| Anterior Quadratus Lumborum Block (QLB)In the Quadratus Lumborum block group, in the lateral decubitus position, a convex ultrasound probe will be sterilely placed in the subcostal area and above the iliac crest. The quadratus lumborum and psoas major muscles, as well as the L4 vertebra's transverse process, will be visualized. Using the in-plane technique and a 22G 100 mm peripheral block needle, the placement will first be identified through hydrodissection in the subfascial area between the quadratus lumborum and psoas major muscles. After localization, 20 mL of 0.25% bupivacaine will be injected slowly, aspirating every 5 cc, while visualizing the local anesthetic pushing the fascia in the ultrasound image. | Procedure or surgery | anterior quadratus lumborum block |
Primary outcome
time to first rescue analgesic requirement.
Time frame: 24 hour
Our primary aim is to compare and evaluate the time to first rescue analgesic requirement after the application of anterior Quadratus Lumborum Block and Transversalis Fascia Plane Block in patients undergoing elective inguinal hernia surgeries under spinal anesthesia.
2 secondary outcomes
Total Opioid Consumption
Time frame: 24 hour
To compare the NRS (Numering rating scale) values (resting and dynamic) at 2. 4. 8. 12 . 24. hours in the postoperative follow-up of the patients
Time frame: 24 hour
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Jul 2026.
- Results publication: PubMed 33307633Abdelbaser I, Mageed NA, El-Emam EM, ALseoudy MM, Elmorsy MM. Preemptive analgesic efficacy of ultrasound-guided transversalis fascia plane block in children undergoing inguinal herniorrhaphy: a randomized, double-blind, controlled study. Korean J Anesthesiol. 2021 Aug;74(4):325-332. doi: 10.4097/kja.20601. Epub 2020 Dec 14.
- Results publication: PubMed 32030845Samerchua A, Leurcharusmee P, Panichpichate K, Bunchungmongkol N, Wanvoharn M, Tepmalai K, Khorana J, Chantakhow S. A Prospective, randomized comparative study between ultrasound-guided posterior quadratus lumborum block and ultrasound-guided ilioinguinal/iliohypogastric nerve block for pediatric inguinal herniotomy. Paediatr Anaesth. 2020 Apr;30(4):498-505. doi: 10.1111/pan.13837. Epub 2020 Feb 21.
- Results publication: PubMed 31623572Ahmed A, Fawzy M, Nasr MAR, Hussam AM, Fouad E, Aboeldahb H, Saad D, Osman S, Fahmy RS, Farid M, Waheb MM. Ultrasound-guided quadratus lumborum block for postoperative pain control in patients undergoing unilateral inguinal hernia repair, a comparative study between two approaches. BMC Anesthesiol. 2019 Oct 17;19(1):184. doi: 10.1186/s12871-019-0862-z.
- Individual participant dataSharing planned: Yes. The data associated with the paper are not publicly available but are available from the corresponding author on reasonable request.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Serpil Sehirlioglu, MD principal investigator
Gaziosmanpasa Research and Education Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Transversalis Fascia Plane Block and Anterior Quadratus Lumborum Block (QLB) in people with Pain, Postoperative, run by Gaziosmanpasa Research and Education Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 7 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact serpil Sehirlioglu, MD (+905054431852, drserpilsahin@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
time to first rescue analgesic requirement. (time frame: 24 hour). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06664177, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Jul 2026.