SuicideTESPNCT06660199
Text-based Support for Parents of Adolescents Following an Emergency Department Visits
A study testing Text-based intervention in people with Suicide, run by University of Michigan at 2 sites in United States.
Trial summary
The goal of this study is to determine the effectiveness of an adaptive text-based intervention for parents of adolescents seeking emergency department services for suicide risk concerns. Read more about this study
- Who is it for?
- Ages 13 years and older
- Conditions the study is for
- Suicide
- What is being tested?
- Text-based intervention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 420 participants
- Where
- 2 sitesUnited States
- Study dates
- 1 Dec 2025to Jul 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 13 years and older
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Who may be able to join
- Adolescent (13-17 years old) who present to Emergency Department (ED) due to (1) last-week suicidal ideation and/or (2) last-month suicide attempt, and their caregiver.
Who cannot join
- Adolescents who are:
- medically unstable
- presenting with severe cognitive impairment, altered mental status, severe aggression/agitation
- presenting without a legal guardian
- whose parent does not own a cell phone
Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
United States2 sites, 2 recruiting
- Recruiting
University of Michigan
Ann Arbor, Michigan, 48109
Ewa Czyz, PhD, 734-764-9466, ewac@umich.edu
Ewa Czyz, PhD
- Recruiting
Hurley Medical Center
Flint, Michigan, 48503
Courtney Mangus, M.D., 810-262-9429, cmangus@med.umich.edu
Courtney Mangus, M.D.
About this study
Official title: Effectiveness of Text-based Support for Parents of Suicidal Adolescents Following Emergency Department Visits
The goal of this study is to determine the effectiveness of an adaptive text-based intervention for parents of adolescents seeking emergency department services for suicide risk concerns.
Read the detailed description
Participants will be 420 adolescents (ages 13-17) seen in ED with recent suicidal ideation and/or attempt and their parents recruited from two health system EDs in the Midwest.
- Conditions
- Suicide
- Being tested
- Text-based intervention
- Keywords
- Text, Suicidal Ideation, Suicide Attempt
- Medical subject headings
- Suicide, Suicidal Ideation, Suicide, Attempted
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Text-based interventionBehavioural
Parents randomized to the texting intervention will receive up to 3 messages each day for 6 weeks: The intervention is comprised of adolescent-centered (A-C) texts focusing on parental adherence to recommended suicide prevention strategies to promote adolescents' safety and parent-centered (P-C) texts focused on improving parents' own well-being.
| Study group | Role | What they receive |
|---|---|---|
| Standard ED care | No intervention | Not described |
| Standard ED care with a text-based intervention | Experimental | This arm incorporates adolescent-centered (A-C) and parent-centered (P-C) texting components
Parents in the intervention arm will receive up to 3 text messages per day over six weeks after ED discharge: daily A-C text and up to two P-C messages. The P-C component includes an embedded micro-randomized trial (MRT), and parents will be randomized twice each day over the six-week intervention to either receive or not receive a P-C message. Receives: Behavioral: Text-based intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Aim 1 (primary aim): likelihood of suicidal behavior (actual, interrupted, or aborted attempts)
Suicidal behavior encompasses actual, interrupted, and aborted suicide attempts. Measured with the behavioral subscale of the Columbia-Suicide Severity Rating Scale (C-SSRS),and supplemented with available medical chart data.
Measured: 12-week follow-up
Aim 2 (secondary aim) severity of parental stress
Measured with twice daily surveys over the 6-week intervention
Measured: Up to 6 weeks
Secondary outcomes (4)
Aim 1 (primary aim): -time- to- suicidal behavior (actual, interrupted, or aborted suicide attempts
Measured with the behavioral subscale of C-SSRS and supplemented with available chart data.
Measured: 24-week follow-up
Aim 1 (primary aim): time- to- return ED visit
Measured: 24-week follow-up.
Aim 2 (secondary aim): parental negative affect
Measured with twice daily surveys over the 6-week intervention.
Measured: Up to 6 weeks
Aim 2 (secondary aim) parental positive affect
Measured with twice daily surveys over the 6-week intervention.
Measured: Up to 6 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Oct 2024
- Study start1 Dec 2025
- Primary completionJul 2028 (estimated)
- Study completionJul 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for SuicideStudies of the same condition, open and under way.
- More trials run by University of MichiganThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 420 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Michigan
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute of Mental Health (NIMH)
- Responsible party
- Principal investigator, Ewa Czyz, University of Michigan
- Investigators
- Ewa Czyz, Ph.D., Principal investigator, University of Michigan
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06660199
- Sponsor's protocol ID
- HUM00254540
- Other IDs
- 1R01MH137012-01
- Acronym
- TESP
- Status last verified
- Dec 2025
- First submitted
- 23 Oct 2024
- Last updated
- 15 Dec 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of Text-based Support for Parents of Suicidal Adolescents Following Emergency Department Visits
- ClinicalTrials.gov ID
- NCT06660199
- Acronym / sponsor ID
- TESP / HUM00254540
- Conditions
- Suicide
- Keywords
- Text, Suicidal Ideation, Suicide Attempt
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 420 participants (estimated)
- Lead sponsor
- University of MichiganUniversity, hospital or other
- Collaborators
- National Institute of Mental Health (NIMH)
- Study start
- 1 Dec 2025 (actual)
- Primary completion
- Jul 2028 (estimated)
- Study completion
- Jul 2028 (estimated)
- First posted
- 28 Oct 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this study is to determine the effectiveness of an adaptive text-based intervention for parents of adolescents seeking emergency department services for suicide risk concerns.
Detailed description
Participants will be 420 adolescents (ages 13-17) seen in ED with recent suicidal ideation and/or attempt and their parents recruited from two health system EDs in the Midwest.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Standard ED care | No intervention | – |
| Standard ED care with a text-based intervention | Experimental | Behavioral: Text-based interventionThis arm incorporates adolescent-centered (A-C) and parent-centered (P-C) texting components Parents in the intervention arm will receive up to 3 text messages per day over six weeks after ED discharge: daily A-C text and up to two P-C messages. The P-C component includes an embedded micro-randomized trial (MRT), and parents will be randomized twice each day over the six-week intervention to either receive or not receive a P-C message. |
Who may qualify
- Ages
- 13 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (1 listed)
- Adolescent (13-17 years old) who present to Emergency Department (ED) due to (1) last-week suicidal ideation and/or (2) last-month suicide attempt, and their caregiver.
Key exclusion criteria (5 listed)
- medically unstable
- presenting with severe cognitive impairment, altered mental status, severe aggression/agitation
- presenting without a legal guardian
- whose parent does not own a cell phone
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Text-based interventionParents randomized to the texting intervention will receive up to 3 messages each day for 6 weeks: The intervention is comprised of adolescent-centered (A-C) texts focusing on parental adherence to recommended suicide prevention strategies to promote adolescents' safety and parent-centered (P-C) texts focused on improving parents' own well-being. | Behavioural | Standard ED care with a text-based intervention |
Primary outcome
Aim 1 (primary aim): likelihood of suicidal behavior (actual, interrupted, or aborted attempts)
Time frame: 12-week follow-up
Suicidal behavior encompasses actual, interrupted, and aborted suicide attempts. Measured with the behavioral subscale of the Columbia-Suicide Severity Rating Scale (C-SSRS),and supplemented with available medical chart data.
Aim 2 (secondary aim) severity of parental stress
Time frame: Up to 6 weeks
Measured with twice daily surveys over the 6-week intervention
4 secondary outcomes
Aim 1 (primary aim): -time- to- suicidal behavior (actual, interrupted, or aborted suicide attempts
Time frame: 24-week follow-up
Aim 1 (primary aim): time- to- return ED visit
Time frame: 24-week follow-up.
Aim 2 (secondary aim): parental negative affect
Time frame: Up to 6 weeks
Aim 2 (secondary aim) parental positive affect
Time frame: Up to 6 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Dec 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Ewa Czyz, Ph.D. principal investigator
University of Michigan
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Text-based intervention in people with Suicide, run by University of Michigan at 2 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 15 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ewa Czyz, Ph.D. (734-764-9466, ewac@umich.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Aim 1 (primary aim): likelihood of suicidal behavior (actual, interrupted, or aborted attempts) (time frame: 12-week follow-up). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Dec 2025; AzTrials last refreshed its copy on 26 Oct 2026.