WSO BEAT STROKE Initiative

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

• Ages 18 years and older
• All sexes
• No healthy volunteers
• Adult, Older adult

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

About this study

Official title: WSO - The Brain and hEart globAl iniTiative (BEAT) Stroke

Conditions

Stroke, PFO - Patent Foramen Ovale, Atrial Fibrillation (AF)

Being tested

Educational and implementation Neurocardiology tool, No educational or implementation tool will be provided

Keywords

cardiac monitoring, stroke, atrial fibrillation, pfo closure

Medical subject headings

Stroke, Foramen Ovale, Patent, Atrial Fibrillation

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

• Educational and implementation Neurocardiology toolOther

  Sites randomized to the intervention arm will receive an educational and implementation-focused Neurocardiology tool designed to enhance adherence to best practice recommendations for secondary prevention of cardioembolic stroke. These recommendations are based on the World Stroke Organization (WSO) Systematic Review and Synthesis of Global Stroke Guidelines, supplemented by any high-quality evidence published after the most recent stroke guidelines. In addition, participating sites will be provided with 14-day Holter monitors for all patients enrolled in the study.

• No educational or implementation tool will be providedOther

  Participants in the non-intervention arm will be followed for up to 12 months. Sites randomized to this arm will not receive any educational or implementation tools during the follow-up period. After the 12-month follow-up has been completed, sites may be provided with access to the Neurocardiology tool.

What is being measured

The primary outcome is the main question the study is designed to answer.

1. Difference between the baseline and 6-month mean WSO BEAT-STROKE Neurocardiology Score

   Difference between baseline and 6-month mean World Stroke Organization Brain and Heart global Initiative Stroke (WSO BEAT-STROKE) Evaluation for Adherence to Treatment Neurocardiology Score

   Description: The WSO BEAT-STROKE Neurocardiology Score is a composite scale used to measure adherence to best practice recommendations for the secondary prevention of cardioembolic stroke. It is composed of 8 categories (initial workup, stroke-heart syndrome, ESUS workup, patent foramen ovale, atrial fibrillation management, etc.) with a weighted scoring system (see Table 1).

   Scale range: 0 (no adherence) to 10 (full adherence).

   Interpretation: Higher scores indicate greater adherence to guideline-recommended care.

   Calculation: Each patient's score is calculated by dividing the total points achieved by the total possible points for which the patient is eligible, as not all patients qualify for ESUS, PFO, or AF items.

   Measured: 6-months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

1. First posted20 Sep 2024
2. Study startMar 2027 (estimated)
3. Primary completionMar 2028 (estimated)
4. Study completionDec 2029 (estimated)

Resources

• Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
• Other trials for StrokeStudies of the same condition, open and under way.
• What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.