Rate of Canine RetractionNCT06481761
The Effectiveness of Double-slot Brackets Versus Single-slot Brackets on the Rate of Canine Retraction
A study testing Double-slot brackets and Single-slot brackets in people with Rate of Canine Retraction, run by Cairo University at 1 site in Egypt.
Trial summary
The aim of this Randomized clinical trial is to compare the efficacy of the double slot brackets compared to single slot-brackets in producing a controlled rate of upper canine retraction into premolar extraction space. Read more about this study
- Who is it for?
- Ages 16 to 26 yearsHealthy volunteers can take part
- Conditions the study is for
- Rate of Canine Retraction
- What is being tested?
- Double-slot brackets and Single-slot brackets
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteEgypt
- Study dates
- 19 Oct 2024to 26 Jan 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 16 to 26 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- Good oral hygiene.
- Adult Male or Female patients with an age range of 16-26 years old.
- Full set of permanent dentition(excluding third molar).
- Any kind of malocclusion requiring first premolar extraction and canine retraction.
- Patients with type/pattern of crowding that allows leveling and alignment before premolar extraction
Who cannot join
- History of previous orthodontic treatment.
- Craniofacial deformity.
- Systematic disease or administrating drugs affecting tooth movement.
- Poor oral health.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Effectiveness of Double-slot Brackets Versus Single-slot Brackets on the Rate of Canine Retraction: A Randomized Clinical Trial
The aim of this Randomized clinical trial is to compare the efficacy of the double slot brackets compared to single slot-brackets in producing a controlled rate of upper canine retraction into premolar extraction space.
patients will be randomly divided into one of the two groups, CBCT (cone beam computed tomography) and dental models will be taken for each patient Pre-retraction and following the study completion.
The rate of retraction will be evaluated for both groups as well as Amount of canine root movement and molar anchorage loss will be also assessed.
Read the detailed description
Eligible patients will be examined for fulfilling the inclusion criteria. All the recruited patients need extraction of upper first premolars followed by canine retraction with maximum anchorage.
The patients will be randomly allocated to one of the two groups; either Double slot brackets or single slot-brackets group.
In Double slot bracket group, Canine retraction will be made on two 0.016'' StSt (stainless steel) round wires, each in one of the slots of the double slot brackets. while in single slot-bracket group, Retraction will be made on one 0.017''×0.025'' rectangular StSt arch wire .
The patients will be seen on a monthly basis for follow up visit for reactivation of retraction to maintain constant force during the study. An impression will be taken for the patients every visit, fabricated dental models will be digitally scanned. The scanned models will be used to monitor the rate of canine retraction.
Every patient will be asked to take a CBCT image of the upper arch pre Retraction and after the completion of study duration (3 months). After data collection, assessors will carry on the measurements blindly. Statistical analysis of the data will be done and the results will be compared to evaluate the effectiveness of both techniques for canine retraction.
- Conditions
- Rate of Canine Retraction
- Being tested
- Double-slot brackets, Single-slot brackets
- Keywords
- canine retraction, double slot brackets, Orthodontic tooth movement
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Double-slot bracketsDevice
Miniscrews will be inserted in the buccal alveolar bone between first and second molars bilaterally and ligated to second premolar.
Canine Retraction using Nickel titanium closed-coil springs delivering a force of 150 gram, extending the spring between the canine and first molar hooks.
retraction on double 0.016'' Stainless steel round wires in both slots of the double slot brackets.
Re-activation of the coil spring will be done in the follow up visits to maintain a constant force through the study.
Single-slot bracketsDevice
Miniscrews will be inserted in the buccal alveolar bone between first and second molars bilaterally and ligated to second premolar.
Canine Retraction using Nickel titanium closed-coil springs delivering a force of 150 gram, extending the spring between the canine and first molar hooks.
retraction on single 0.017x0.022'' Stainless steel wire. Re-activation of the coil spring will be done in the follow up visits to maintain a constant force through the study.
| Study group | Role | What they receive |
|---|---|---|
| Single-slot brackets | Active comparator | Bonding of the upper arch up to second molars with Roth prescription 0.022x.028" single slot brackets (MINI MS-American orthodontics) Receives: Device: Single-slot brackets |
| Double-slot brackets | Experimental | Double slot brackets (SORTECH-South Orthodontic Technology) will be Bonded on the upper arch up to the second molars. The brackets are of Roth prescription \& have two slots, cervical 0.018x.025" slot and incisal/occlusal 0.022x.028" slot Receives: Device: Double-slot brackets |
What is being measured
The primary outcome is the main question the study is designed to answer.
rate of canine retraction
millimeters through superimposed digital models taken for each patient monthly at the follow up visits.
Measured: 3 months
Secondary outcomes (7)
Total distance moved by the maxillary canine tip
movement in millimeters through superimposed pre- and post-retraction digital models.
Measured: 3 months
Amount of canine root movement
millimeters through pre and post retraction CBCT (cone beam computed tomography) images of the upper arch
Measured: 3 months
the change in Maxillary canine Torque
angular change through comparing pre- and post-retraction CBCT
Measured: 3 months
change in maxillary canine tipping
angular change through comparing pre- and post-retraction CBCT
Measured: 3 months
The changes in maxillary canine rotation
angular change through superimposed pre- and post-retraction digital models.
Measured: 3 months
Amount of maxillary canine root resorption
millimeters through pre and post retraction CBCT (cone beam computed tomography) images of the upper arch
Measured: 3 months
Molar cusp anchorage loss
millimeters through superimposed digital models taken for each patient monthly at the follow up visits. and pre and post retraction CBCT images
Measured: 3 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Jul 2024
- Study start19 Oct 2024
- Primary completion26 Jan 2025
- Study completion26 Jan 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Rate of Canine RetractionStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- study is a randomized clinical trial, single-center, parallel group, two-arms with 1:1 allocation ratio
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Raghad Mohsen Ghoneim, Cairo University
- Investigators
- Amr R El Beialy, Assoc.Prof, Study chair, Orthodontic department, Faculty of Dentistry, Cairo UniversityNada O El Zawahry, lecturer, Study director, Orthodontic department, Faculty of Dentistry, Cairo UniversityNoha A El Ashmawi, lecturer, Study director, Orthodontic department, Faculty of Dentistry, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06481761
- Sponsor's protocol ID
- Orth3-3-2
- Status last verified
- Jun 2026
- First submitted
- 24 Jun 2024
- Last updated
- 26 Jun 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effectiveness of Double-slot Brackets Versus Single-slot Brackets on the Rate of Canine Retraction: A Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT06481761
- Acronym / sponsor ID
- Orth3-3-2
- Conditions
- Rate of Canine Retraction
- Keywords
- canine retraction, double slot brackets, Orthodontic tooth movement
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 19 Oct 2024 (actual)
- Primary completion
- 26 Jan 2025 (actual)
- Study completion
- 26 Jan 2025 (actual)
- First posted
- 1 Jul 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this Randomized clinical trial is to compare the efficacy of the double slot brackets compared to single slot-brackets in producing a controlled rate of upper canine retraction into premolar extraction space.
patients will be randomly divided into one of the two groups, CBCT (cone beam computed tomography) and dental models will be taken for each patient Pre-retraction and following the study completion.
The rate of retraction will be evaluated for both groups as well as Amount of canine root movement and molar anchorage loss will be also assessed.
Detailed description
Eligible patients will be examined for fulfilling the inclusion criteria. All the recruited patients need extraction of upper first premolars followed by canine retraction with maximum anchorage.
The patients will be randomly allocated to one of the two groups; either Double slot brackets or single slot-brackets group.
In Double slot bracket group, Canine retraction will be made on two 0.016'' StSt (stainless steel) round wires, each in one of the slots of the double slot brackets. while in single slot-bracket group, Retraction will be made on one 0.017''×0.025'' rectangular StSt arch wire .
The patients will be seen on a monthly basis for follow up visit for reactivation of retraction to maintain constant force during the study. An impression will be taken for the patients every visit, fabricated dental models will be digitally scanned. The scanned models will be used to monitor the rate of canine retraction.
Every patient will be asked to take a CBCT image of the upper arch pre Retraction and after the completion of study duration (3 months). After data collection, assessors will carry on the measurements blindly. Statistical analysis of the data will be done and the results will be compared to evaluate the effectiveness of both techniques for canine retraction.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- study is a randomized clinical trial, single-center, parallel group, two-arms with 1:1 allocation ratio
| Arm | Type | Receives |
|---|---|---|
| Single-slot brackets | Active comparator | Device: Single-slot bracketsBonding of the upper arch up to second molars with Roth prescription 0.022x.028" single slot brackets (MINI MS-American orthodontics) |
| Double-slot brackets | Experimental | Device: Double-slot bracketsDouble slot brackets (SORTECH-South Orthodontic Technology) will be Bonded on the upper arch up to the second molars. The brackets are of Roth prescription \& have two slots, cervical 0.018x.025" slot and incisal/occlusal 0.022x.028" slot |
Who may qualify
- Ages
- 16 to 26 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (5 listed)
- Good oral hygiene.
- Adult Male or Female patients with an age range of 16-26 years old.
- Full set of permanent dentition(excluding third molar).
- Any kind of malocclusion requiring first premolar extraction and canine retraction.
- Patients with type/pattern of crowding that allows leveling and alignment before premolar extraction
Key exclusion criteria (4 listed)
- History of previous orthodontic treatment.
- Craniofacial deformity.
- Systematic disease or administrating drugs affecting tooth movement.
- Poor oral health.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Double-slot bracketsMiniscrews will be inserted in the buccal alveolar bone between first and second molars bilaterally and ligated to second premolar. Canine Retraction using Nickel titanium closed-coil springs delivering a force of 150 gram, extending the spring between the canine and first molar hooks. retraction on double 0.016'' Stainless steel round wires in both slots of the double slot brackets. Re-activation of the coil spring will be done in the follow up visits to maintain a constant force through the study. | Device | Double-slot brackets |
| Single-slot bracketsMiniscrews will be inserted in the buccal alveolar bone between first and second molars bilaterally and ligated to second premolar. Canine Retraction using Nickel titanium closed-coil springs delivering a force of 150 gram, extending the spring between the canine and first molar hooks. retraction on single 0.017x0.022'' Stainless steel wire. Re-activation of the coil spring will be done in the follow up visits to maintain a constant force through the study. | Device | Single-slot brackets |
Primary outcome
rate of canine retraction
Time frame: 3 months
millimeters through superimposed digital models taken for each patient monthly at the follow up visits.
7 secondary outcomes
Total distance moved by the maxillary canine tip
Time frame: 3 months
Amount of canine root movement
Time frame: 3 months
the change in Maxillary canine Torque
Time frame: 3 months
change in maxillary canine tipping
Time frame: 3 months
The changes in maxillary canine rotation
Time frame: 3 months
Amount of maxillary canine root resorption
Time frame: 3 months
Molar cusp anchorage loss
Time frame: 3 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Jun 2026.
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Comparison of Rate of Tooth Movement Between MOPs vs MOPs & LLLT Combined
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Comparison of Canine Retraction Using Ni-ti Closed-coil Springs Vs Elastomeric Power Chains During Orthodontic Treatment
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Amr R El Beialy, Assoc.Prof study chair
Orthodontic department, Faculty of Dentistry, Cairo University
Nada O El Zawahry, lecturer study director
Orthodontic department, Faculty of Dentistry, Cairo University
Noha A El Ashmawi, lecturer study director
Orthodontic department, Faculty of Dentistry, Cairo University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Double-slot brackets and Single-slot brackets in people with Rate of Canine Retraction, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 26 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
rate of canine retraction (time frame: 3 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Jun 2026.