Piriformis SyndromeNCT06460675
Comparasion of Autogenic Inhibition and Reciprocal Inhibition Muscle Energy Techniques (METS) in Piriformis Syndrome
A study testing Autogenic Inhibition Muscle Energy Technique and Reciprocal Inhibition Muscle Energy Technique in people with Piriformis Syndrome, run by Riphah International University at 1 site in Pakistan.
Trial summary
To compare the effects of Autogenic Inhibition and Reciprocal Inhibition Muscle Energy Techniques (METS) in Piriformis Syndrome Read more about this study
- Who is it for?
- Ages 25 to 45 years
- Conditions the study is for
- Piriformis Syndrome
- What is being tested?
- Autogenic Inhibition Muscle Energy Technique and Reciprocal Inhibition Muscle Energy Technique
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 32 participants
- Where
- 1 sitePakistan
- Study dates
- 1 Feb 2024to 10 Nov 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 45 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Both genders with ages between 25-45 years.
- Patients diagnosed with Piriformis syndrome using the Piriformis FAIR test, Freiberg test, Lasegue test, Beaty test, and pace sign.
- Hip pain with a threshold of NPRS 3-6.
- Limited ROM of Hip Internal Rotation and Abduction measured using a goniometer.
- Buttock pain ≥ 3 months.
- Pain with prolonged sitting (more than 20 minutes)
Who cannot join
- Hip Degenerative changes.
- History of Trauma or Fracture
- Other Systemic Conditions
- Postural abnormality/deformity
- Diagnosed Psychological Disorders
- Pregnancy
Trial locations and contacts
1 site in 1 country.
Pakistan1 site, 1 recruiting
- Recruiting
IIMCT Railway General Hospital
Rawalpindi, Punjab Province, 46000
Iqra Khan, M.phil, 03354671744, iqrakhan485@gmail.com
Mateen Asghar, MS(OMPT)
About this study
Official title: Comparative Effects of Autogenic Inhibition and Reciprocal Inhibition Muscle Energy Techniques in Piriformis Syndrome
To compare the effects of Autogenic Inhibition and Reciprocal Inhibition Muscle Energy Techniques (METS) in Piriformis Syndrome
Read the detailed description
Piriformis syndrome is when the piriformis muscle, located in the buttock region, spasms and causes buttock pain. The piriformis muscle also can irritate the nearby sciatic nerve and cause pain, numbness, and tingling along the back of the leg and into the foot (similar to sciatic pain). The functional limitations experienced by hip pain patients in the lower limb profoundly impact their quality of life. This study aims to investigate the effectiveness of an integrated approach that compares the Effects of Autogenic Inhibition versus Reciprocal Inhibition Muscle Energy Techniques on Pain, Range of motion, and Disability in patients with Piriformis Syndrome.
This randomized clinical trial will be conducted at DHQ Hospital Jhang over six months. The sample size will consist of 32 participants. Participants who meet the inclusion criteria will be taken through a non-probability convenience sampling technique, that will be randomized through a sealed envelope method. 16 Participants will be assigned to Group A that will be treated with the Autogenic Inhibition Muscle Energy Technique, 16 Participants will be assigned to Group B and will be treated with Reciprocal Inhibition Muscle Energy Technique at the frequency of 1 set and 3 repetitions per session for two sessions per week and total six sessions for three weeks with follow up at one month. The duration of contraction is 7-10 seconds. Pre and post-intervention values will be taken on the 1st day in the 3rd week and at one-month follow-up. Data will be collected using various assessment tools, including the FAIR test, Freiberg test, Lasegue test, Beatty test, Pace sign, Numeric Pain Rating Scale (NPRS), and Universal Goniometer. Pre-intervention assessments will be conducted for all two groups. The effects of the interventions will be measured either by parametric or non-parametric tests after assessing the normality of data by the Shapiro-Wilk test Independent t-test. Data analysis will be performed by using SPSS 25 software.
- Conditions
- Piriformis Syndrome
- Being tested
- Autogenic Inhibition Muscle Energy Technique, Reciprocal Inhibition Muscle Energy Technique
- Keywords
- Exercise, Manipulative therapies, Pain, Piriformis Syndrome, Range of Motion, Sciatic Nerve
- Medical subject headings
- Piriformis Muscle Syndrome, Motor Activity, Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Autogenic Inhibition Muscle Energy TechniqueProcedure or surgery
No of repetitions: 1 set with 3 repetitions No of Sessions per week: 2 per weeks for 3 weeks (40 Min per Session)
Reciprocal Inhibition Muscle Energy TechniqueProcedure or surgery
No of repetitions: 1 set with 3 repetitions No of Sessions per week: 2 per week for 3 weeks (40 Min per Session)
| Study group | Role | What they receive |
|---|---|---|
| Autogenic Inhibition Muscle Energy Technique | Experimental | This group will receive Autogenic Inhibition Muscle Energy Technique Receives: Procedure: Autogenic Inhibition Muscle Energy Technique; Procedure: Reciprocal Inhibition Muscle Energy Technique |
| Reciprocal Inhibition Muscle Energy Technique | Active comparator | This group will receive Reciprocal Inhibition Muscle Energy Technique Receives: Procedure: Autogenic Inhibition Muscle Energy Technique; Procedure: Reciprocal Inhibition Muscle Energy Technique |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain : Numeric Pain Rating Scale (NPRS)
Patients' overall assessment of pain will be provided using the numeric pain rating scale
Measured: 3 Weeks
Range of Motion : Universal Goniometer
It is frequently employed as a benchmark technique for the assessment of Range of Motion
Measured: 3 Weeks
Lower Extremity Functional Scale (LEFS)
The LEFS is a self-report questionnaire intended to assess functional status in patients with disability of the lower extremity (e.g., hip, thigh, ankle) containing 20 questions about a person's ability to perform everyday tasks
Measured: 3 Weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Jun 2024
- Study start1 Feb 2024
- Primary completion10 Oct 2024 (estimated)
- Study completion10 Nov 2024 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (10)Papers the sponsor has linked to this study.
- Other trials for Piriformis SyndromeStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 32 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Rabiya Noor, PhD, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06460675
- Sponsor's protocol ID
- REC/RCR & AHS/23/01114
- Status last verified
- Jun 2024
- First submitted
- 11 Jun 2024
- Last updated
- 14 Jun 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Sadiq M, Hussain SA, Meganath P. 'Hand on hip'sign: A novel screening test and diagnostic tool in piriformis syndrome. Journal of Orthopaedics, Trauma and Rehabilitation. 2020:2210491720961113.
Siahaan YMT, Tiffani P, Tanasia A. Ultrasound-Guided Measurement of Piriformis Muscle Thickness to Diagnose Piriformis Syndrome. Front Neurol. 2021 Sep 7;12:721966. doi: 10.3389/fneur.2021.721966. eCollection 2021.
PubMed 34557150Tanveer F, Shahid S. Frequency of Piriformis tightness in professionals middle aged women. Rawal Medical Journal. 2018;43(4):685-.
Hopayian K, Danielyan A. Four symptoms define the piriformis syndrome: an updated systematic review of its clinical features. Eur J Orthop Surg Traumatol. 2018 Feb;28(2):155-164. doi: 10.1007/s00590-017-2031-8. Epub 2017 Aug 23.
PubMed 28836092Siahaan YMT, Ketaren RJ, Hartoyo V, Tiffani P. The predisposing factors of piriformis syndrome: Study in a referral hospital. MNJ (Malang Neurology Journal). 2019;5(2):76-9.
Wu YY, Guo XY, Chen K, He FD, Quan JR. Feasibility and Reliability of an Ultrasound Examination to Diagnose Piriformis Syndrome. World Neurosurg. 2020 Feb;134:e1085-e1092. doi: 10.1016/j.wneu.2019.11.098. Epub 2019 Nov 25.
PubMed 31778837Islam F, Mansha H, Gulzar K, Raza A, Raffique A, Haider S. Prevalence Of Piriformis Muscle Syndrome Among Individuals with Low Back Pain: Piriformis Muscle Syndrome Among Individuals with Low Back Pain. Pakistan Journal of Health Sciences. 2022:48-52.
Probst D, Stout A, Hunt D. Piriformis Syndrome: A Narrative Review of the Anatomy, Diagnosis, and Treatment. PM R. 2019 Aug;11 Suppl 1:S54-S63. doi: 10.1002/pmrj.12189. Epub 2019 Jul 22.
PubMed 31102324Ahmad Siraj S, Dadgal R. Physiotherapy for Piriformis Syndrome Using Sciatic Nerve Mobilization and Piriformis Release. Cureus. 2022 Dec 26;14(12):e32952. doi: 10.7759/cureus.32952. eCollection 2022 Dec.
PubMed 36712711Chang C, Jeno SH, Varacallo MA. Anatomy, Bony Pelvis and Lower Limb: Piriformis Muscle. 2023 Nov 13. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK519497/
PubMed 30137781
Study at a glance
From the registry record, last updated by the sponsor on 14 Jun 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effects of Autogenic Inhibition and Reciprocal Inhibition Muscle Energy Techniques in Piriformis Syndrome
- ClinicalTrials.gov ID
- NCT06460675
- Acronym / sponsor ID
- REC/RCR & AHS/23/01114
- Conditions
- Piriformis Syndrome
- Keywords
- Exercise, Manipulative therapies, Pain, Piriformis Syndrome, Range of Motion, Sciatic Nerve
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 32 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 1 Feb 2024 (actual)
- Primary completion
- 10 Oct 2024 (estimated)
- Study completion
- 10 Nov 2024 (estimated)
- First posted
- 14 Jun 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To compare the effects of Autogenic Inhibition and Reciprocal Inhibition Muscle Energy Techniques (METS) in Piriformis Syndrome
Detailed description
Piriformis syndrome is when the piriformis muscle, located in the buttock region, spasms and causes buttock pain. The piriformis muscle also can irritate the nearby sciatic nerve and cause pain, numbness, and tingling along the back of the leg and into the foot (similar to sciatic pain). The functional limitations experienced by hip pain patients in the lower limb profoundly impact their quality of life. This study aims to investigate the effectiveness of an integrated approach that compares the Effects of Autogenic Inhibition versus Reciprocal Inhibition Muscle Energy Techniques on Pain, Range of motion, and Disability in patients with Piriformis Syndrome.
This randomized clinical trial will be conducted at DHQ Hospital Jhang over six months. The sample size will consist of 32 participants. Participants who meet the inclusion criteria will be taken through a non-probability convenience sampling technique, that will be randomized through a sealed envelope method. 16 Participants will be assigned to Group A that will be treated with the Autogenic Inhibition Muscle Energy Technique, 16 Participants will be assigned to Group B and will be treated with Reciprocal Inhibition Muscle Energy Technique at the frequency of 1 set and 3 repetitions per session for two sessions per week and total six sessions for three weeks with follow up at one month. The duration of contraction is 7-10 seconds. Pre and post-intervention values will be taken on the 1st day in the 3rd week and at one-month follow-up. Data will be collected using various assessment tools, including the FAIR test, Freiberg test, Lasegue test, Beatty test, Pace sign, Numeric Pain Rating Scale (NPRS), and Universal Goniometer. Pre-intervention assessments will be conducted for all two groups. The effects of the interventions will be measured either by parametric or non-parametric tests after assessing the normality of data by the Shapiro-Wilk test Independent t-test. Data analysis will be performed by using SPSS 25 software.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Autogenic Inhibition Muscle Energy Technique | Experimental | Procedure: Autogenic Inhibition Muscle Energy Technique, Procedure: Reciprocal Inhibition Muscle Energy TechniqueThis group will receive Autogenic Inhibition Muscle Energy Technique |
| Reciprocal Inhibition Muscle Energy Technique | Active comparator | Procedure: Autogenic Inhibition Muscle Energy Technique, Procedure: Reciprocal Inhibition Muscle Energy TechniqueThis group will receive Reciprocal Inhibition Muscle Energy Technique |
Who may qualify
- Ages
- 25 to 45 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Both genders with ages between 25-45 years.
- Patients diagnosed with Piriformis syndrome using the Piriformis FAIR test, Freiberg test, Lasegue test, Beaty test, and pace sign.
- Hip pain with a threshold of NPRS 3-6.
- Limited ROM of Hip Internal Rotation and Abduction measured using a goniometer.
- Buttock pain ≥ 3 months.
Key exclusion criteria (6 listed)
- Hip Degenerative changes.
- History of Trauma or Fracture
- Other Systemic Conditions
- Postural abnormality/deformity
- Diagnosed Psychological Disorders
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Autogenic Inhibition Muscle Energy TechniqueNo of repetitions: 1 set with 3 repetitions No of Sessions per week: 2 per weeks for 3 weeks (40 Min per Session) | Procedure or surgery | Autogenic Inhibition Muscle Energy Technique, Reciprocal Inhibition Muscle Energy Technique |
| Reciprocal Inhibition Muscle Energy TechniqueNo of repetitions: 1 set with 3 repetitions No of Sessions per week: 2 per week for 3 weeks (40 Min per Session) | Procedure or surgery | Autogenic Inhibition Muscle Energy Technique, Reciprocal Inhibition Muscle Energy Technique |
Primary outcome
Pain : Numeric Pain Rating Scale (NPRS)
Time frame: 3 Weeks
Patients' overall assessment of pain will be provided using the numeric pain rating scale
Range of Motion : Universal Goniometer
Time frame: 3 Weeks
It is frequently employed as a benchmark technique for the assessment of Range of Motion
Lower Extremity Functional Scale (LEFS)
Time frame: 3 Weeks
The LEFS is a self-report questionnaire intended to assess functional status in patients with disability of the lower extremity (e.g., hip, thigh, ankle) containing 20 questions about a person's ability to perform everyday tasks
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Jun 2024.
- BackgroundSadiq M, Hussain SA, Meganath P. 'Hand on hip'sign: A novel screening test and diagnostic tool in piriformis syndrome. Journal of Orthopaedics, Trauma and Rehabilitation. 2020:2210491720961113.
- Background: PubMed 34557150Siahaan YMT, Tiffani P, Tanasia A. Ultrasound-Guided Measurement of Piriformis Muscle Thickness to Diagnose Piriformis Syndrome. Front Neurol. 2021 Sep 7;12:721966. doi: 10.3389/fneur.2021.721966. eCollection 2021.
- BackgroundTanveer F, Shahid S. Frequency of Piriformis tightness in professionals middle aged women. Rawal Medical Journal. 2018;43(4):685-.
- Background: PubMed 28836092Hopayian K, Danielyan A. Four symptoms define the piriformis syndrome: an updated systematic review of its clinical features. Eur J Orthop Surg Traumatol. 2018 Feb;28(2):155-164. doi: 10.1007/s00590-017-2031-8. Epub 2017 Aug 23.
- BackgroundSiahaan YMT, Ketaren RJ, Hartoyo V, Tiffani P. The predisposing factors of piriformis syndrome: Study in a referral hospital. MNJ (Malang Neurology Journal). 2019;5(2):76-9.
- Background: PubMed 31778837Wu YY, Guo XY, Chen K, He FD, Quan JR. Feasibility and Reliability of an Ultrasound Examination to Diagnose Piriformis Syndrome. World Neurosurg. 2020 Feb;134:e1085-e1092. doi: 10.1016/j.wneu.2019.11.098. Epub 2019 Nov 25.
- BackgroundIslam F, Mansha H, Gulzar K, Raza A, Raffique A, Haider S. Prevalence Of Piriformis Muscle Syndrome Among Individuals with Low Back Pain: Piriformis Muscle Syndrome Among Individuals with Low Back Pain. Pakistan Journal of Health Sciences. 2022:48-52.
- Background: PubMed 31102324Probst D, Stout A, Hunt D. Piriformis Syndrome: A Narrative Review of the Anatomy, Diagnosis, and Treatment. PM R. 2019 Aug;11 Suppl 1:S54-S63. doi: 10.1002/pmrj.12189. Epub 2019 Jul 22.
- Background: PubMed 36712711Ahmad Siraj S, Dadgal R. Physiotherapy for Piriformis Syndrome Using Sciatic Nerve Mobilization and Piriformis Release. Cureus. 2022 Dec 26;14(12):e32952. doi: 10.7759/cureus.32952. eCollection 2022 Dec.
- Background: PubMed 30137781Chang C, Jeno SH, Varacallo MA. Anatomy, Bony Pelvis and Lower Limb: Piriformis Muscle. 2023 Nov 13. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK519497/
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Rabiya Noor, PhD principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Autogenic Inhibition Muscle Energy Technique and Reciprocal Inhibition Muscle Energy Technique in people with Piriformis Syndrome, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 14 Jun 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Mateen Asghar, MS-DPT (03046368317, mateen04443@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain : Numeric Pain Rating Scale (NPRS) (time frame: 3 Weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06460675, which also lists 10 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Jun 2024.