Overweight or ObesityOVERCOME-ITNCT06360536
Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women
A study testing Resistance Training in people with Overweight or Obesity and Prediabetes or Diabetes, run by University of Alabama at Birmingham at 1 site in United States.
Trial summary
The purpose of this study is to collect preliminary data on the feasibility, acceptability, and potential effects of a novel, remotely delivered resistance training program. Read more about this study
- Who is it for?
- Ages 30 to 64 years, women only
- Conditions the study is for
- Overweight or Obesity, Prediabetes or Diabetes, Prehypertension (Elevated Blood Pressure) or Hypertension
- What is being tested?
- Resistance Training
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 37 participants
- Where
- 1 siteUnited States
- Study dates
- 19 Mar 2026to 30 Jun 2027
- Phase
- Interventional
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 64 years
- Women only
- No healthy volunteers
- Adult
Who may be able to join
- Self-identifies as Black or African American
- Female
- Age 30-64 years
- Insufficient resistance training engagement (<2 sessions/week in the past 6 months)
- AND
- Self-reported or documented diagnosis of at least one of the following conditions: Overweight, obesity, prediabetes, type 2 diabetes, elevated blood pressure, hypertension, or taking medications for any of these conditions
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- Has an internet- connected device (i.e., computer, smartphone) and is willing to use it for intervention delivery
- If indicated during screening, willing to obtain medical clearance for exercise from their healthcare provider prior to enrollment
- Residing within a 50-mile radius of the University
Who cannot join
- Uncontrolled hypertension (blood pressure >160/100 mm Hg)
- Weighing ≥ 450 lbs (upper limit for body composition assessment)
- Conditions or limitations that affect physical activity participation and/or the ability to --perform assessments
- Has a medical or physical condition that make moderate intensity physical activity (like a brisk walk) difficult or unsafe
- Unwilling to obtain medical clearance (if indicated by prescreening)
- Women who are pregnant or trying to become pregnant in the next 6 months
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- Planning to relocate out of the area in the next 6 months
- Participating in another exercise and/or randomized research project
- Unwilling or unable to do any of the following: give informed consent; read/understand English; perform resistance training in their home, record and upload virtual exercise assessment sessions, and other protocol specific requirements
Trial locations and contacts
1 site in 1 country.
United States1 site
University of Alabama at Birmingham
Birmingham, Alabama, 35294
About this study
Official title: Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women: A Pilot Trial
The purpose of this study is to collect preliminary data on the feasibility, acceptability, and potential effects of a novel, remotely delivered resistance training program.
Read the detailed description
This trial will enroll Black women with elevated cardiometabolic risk (e.g., overweight or obesity, pre- or established diabetes, and elevated or high blood pressure) in early-to-middle adulthood (n=36; age=30-64 years) with insufficient resistance training (RT) participation. This 4-month single group pilot trial evaluates the feasibility, acceptability, and potential effects of a novel, remotely-delivered resistance training (RT) intervention. All participants will engage in RT during this trial and the web-based platform is the primary modality through which the remote RT intervention is delivered. Assessments are conducted at baseline and follow-up (month 4). Aim 1 will examine the feasibility and acceptability of the remotely delivered RT program. Aim 2 will examine the potential effects on RT behaviors. Aim 3 will examine the potential effects on clinical and patient-reported outcomes.
- Conditions
- Overweight or Obesity, Prediabetes or Diabetes, Prehypertension (Elevated Blood Pressure) or Hypertension, Resistance Training
- Being tested
- Resistance Training
- Medical subject headings
- Overweight, Obesity, Prediabetic State, Diabetes Mellitus, Prehypertension, Hypertension
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Resistance TrainingBehavioural
Also called RT
A home-based resistance training condition that is delivered through a web-based platform.
| Study group | Role | What they receive |
|---|---|---|
| Intervention/Treatment | Experimental | A home-based resistance training condition that is delivered through a web-based platform. Receives: Behavioral: Resistance Training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Feasibility of recruitment
The number of participants enrolled in the trial
Measured: Baseline
Feasibility of retention
The proportion of participants who complete the study out of those who enrolled in the study
Measured: Month 4
Intervention adherence
The number of participants adhering to the intervention
Measured: Month 4
Secondary outcomes (6)
Change in resistance training behaviors
The number of days of resistance training completed
Measured: Baseline and Month 4
Change in blood pressure
Systolic and diastolic blood pressure measured by an automated device
Measured: Baseline, Month 4
Change in HbA1C
HbA1C measured by a point-of-care device
Measured: Baseline, Month 4
Change in body composition
Percent body fat measured by dual-energy x-ray absorptiometry
Measured: Baseline, Month 4
Change in handgrip strength
The highest value of 3 maximal attempts on each hand
Measured: Baseline, Month 4
Change in the number of chair stands
The number of chair stands completed in 30 seconds
Measured: Baseline, Month 4
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Apr 2024
- Study start19 Mar 2026
- Primary completion8 Oct 2026
- Study completion30 Jun 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Overweight or ObesityStudies of the same condition, open and under way.
- More trials run by University of Alabama at BirminghamThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 37 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Alabama at Birmingham
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute on Minority Health and Health Disparities (NIMHD)
- Responsible party
- Principal investigator, Amber W. Kinsey, PhD, University of Alabama at Birmingham
- Investigators
- Amber W Kinsey, PhD, Principal investigator, University of Alabama at Birmingham
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06360536
- Sponsor's protocol ID
- IRB-300012634
- Other IDs
- P50MD017338
- Acronym
- OVERCOME-IT
- Status last verified
- Oct 2026
- First submitted
- 4 Apr 2024
- Last updated
- 14 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No