AzTrials
AzTrials

Cardiovascular RiskPhase 3ARTEMISNCT06118281

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

A Phase 3 study testing Ziltivekimab in people with Cardiovascular Risk and Acute Myocardial Infarction (AMI), run by Novo Nordisk A/S at 836 sites in 24 countries.

Active, not recruiting

Under way, not looking for participants. Everyone needed has enrolled. The study is still running.

Official record
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Trial summary

The research study is being done to see if ziltivekimab can be used to treat people who were admitted to hospital because of a heart attack. Ziltivekimab might reduce development of heart disease, thereby preventing new heart attacks or strokes. Read more about this study

Who is it for?
Ages 18 years and older
What is being tested?
Ziltivekimab
Type of treatment
Injection or infusion
Could I receive a placebo?
Yes, some participants may receive a placebo
How many people
10,000 participants
Where
836 sitesin 24 countries
Study dates
25 Jun 2024to 29 Jan 2027
Phase
Phase 3
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • Age 18 years or above at the time of signing the informed consent.
  • Hospitalisation for acute myocardial infarction with evidence of type 1 myocardial infarction (MI) by invasive angiography performed at site with percutaneous coronary intervention (PCI) capabilities.
  • ST-segment elevation myocardial infarction (STEMI) with all the following: a) Relevant onset of symptoms suggestive of cardiac ischaemia within 12 hours before hospitalisation, at the investigator's discretion.
  • Electrocardiogram (ECG)-changes (in the absence of left ventricular hypertrophy or left bundle branch block): ST-segment elevation at the J point in at least two contiguous leads greater than or equal 0.25 (millivolt) mV in men less than 40 years, greater than or equal 0.2 mV in men greater than or equal 40 years, or greater than or equal 0.15 mV in women in leads V2-V3; and/or greater than or equal 0.1 mV in all other leads.
  • OR
  • Non-ST-segment myocardial infarction with all the following: a) Relevant onset of symptoms suggestive of cardiac ischaemia within 24 hours before hospitalisation, at the investigator's discretion. b) Rise and/or fall in car-diac troponin I or T with at least one value above the 99th percentile upper reference limit.
  • Possibility for both randomisation and administration of the loading dose of study intervention as early as possible after invasive procedure, and latest within 36 hours of hospitalisation (time 0) for STEMI, and latest within 72 hours of hospitalisation (time 0) for NSTEMI.
  • Presence of at least one of the following criteria confirmed based on the participant's medical records and/or medical history interview: a) Any prior MI. b) Prior coronary revascularisation. c) Diabetes mellitus treated with ongoing glucose-lowering agent(s). d)Known chronic kidney disease (CKD) (estimated glomerular filtration rate (eGFR) greater than or equal to 15 and less than 60 milliliter per minute per 1.73 square meter (mL/min/1.73 m^2). e) Prior ischaemic stroke. f) Known carotid disease or peripheral artery disease in the lower extremities. g) Multivessel coronary artery disease (current/prior). h) For STEMI patients only: anterior MI at index acute myocardial infarction (AMI)

Who cannot join

  • Use of fibrinolytic therapy for treatment of the current AMI.
  • Chronic heart failure classified as being in New York Heart Association (NYHA) Class IV.
  • Ongoing haemodynamic instability defined as any of the following: a) Killip Class III or IV. b) Sustained and/or symptomatic hypotension (systolic blood pressure less than 90 millimeters of mercury (mmHg)).
  • Severe kidney impairment defined as any of the following: a) eGFR less than 15 mililitre per minute per 1.73 m^2. b) Chronic haemodialysis or peritoneal dialysis.
  • Known alanine aminotransferase (ALT) greater than 8 x upper limit of normal (reference range) (ULN).
  • Severe hepatic disease defined as at least one of the following: a) Previously known or current hepatic encephalopathy (clinical evaluation). b) Previously known or current ascites (clinical eval-uation). c) Jaundice (clinical evaluation). d) Previous oesophageal/gastric variceal bleeding. c) Known hepatic cirrhosis.
Show all 10Show fewer
  • Major cardiac surgical (including but not restricted to coronary artery bypass graft surgery (CABG)), non-cardiac surgical, or major endoscopic procedure (thoracoscopic or laparoscopic) within the past 60 days or any major surgical procedure planned at the time of randomisation or as treatment for the current AMI (CABG). Deferred (staged)percutaneous coronary intervention for a non-culprit vessel identified during the current AMI is allowed.
  • Clinical evidence of, or suspicion of, active infection at the discretion of the investigator.
  • Known (acute or chronic) hepatitis B or hepatitis C.
  • History or evidence of untreated latent tuberculosis (TB) such as (but not limited to): a) History of a positive TB test or chest X-ray compatible with latent TB; and TB treatment initiated less than 28 days prior to randomisation. b) Participants with TB risk factors but unwilling to undergo TB treatment if confirmed positive for latent TB based on central laboratory test at baseline (visit 2).

Trial locations and contacts

836 sites in 24 countries.

836 sites in 24 countries

United States188 sites

  • Advanced Cardiovascular, LLC

    Alexander City, Alabama, 35010

  • PharmaTex Research, LLC

    Amarillo, Texas, 79106

  • AnMed Health Clinical Research

    Anderson, South Carolina, 29621

  • Cardiology Associates_Asheville

    Asheville, North Carolina, 28803

  • Emory University Hospital

    Atlanta, Georgia, 30322-1059

  • Augusta University

    Augusta, Georgia, 30912

  • University of CO - Division of Cardiology

    Aurora, Colorado, 80045

  • Austin Heart

    Austin, Texas, 78705

  • Northern Light Eastern Maine Medical Center

    Bangor, Maine, 04401

  • McLaren Bay Region

    Bay City, Michigan, 48708

  • Birmingham VA Medical Center

    Birmingham, Alabama, 35233

  • Grandview Medical Center

    Birmingham, Alabama, 35243

  • Brigham & Women's Hospital

    Boston, Massachusetts, 02115

  • Bridgeport Hospital

    Bridgeport, Connecticut, 06610

  • Advanced Heart Care LLC

    Bridgewater, New Jersey, 08807-3064

  • The New York Hospital

    Brooklyn, New York, 11215

  • Trinity Medical WNY, PC

    Buffalo, New York, 14220

  • Virtua Health

    Camden, New Jersey, 08103

  • Penn State Hlth Holy Spirit Med Ctr

    Camp Hill, Pennsylvania, 17011

  • Aultman Hospital

    Canton, Ohio, 44710

  • Chambersburg Hospital

    Chambersburg, Pennsylvania, 17201

  • UNC Hospital HVC_Meadowmont

    Chapel Hill, North Carolina, 27599-7075

  • Novant Hlth Vasc Ins Charlotte

    Charlotte, North Carolina, 28204

  • University of Virginia

    Charlottesville, Virginia, 22908

  • Chattanooga Heart Institute

    Chattanooga, Tennessee, 37404

  • Lindner Center,Christ Hospital

    Cincinnati, Ohio, 45219

  • University of Cincinnati/UC Health

    Cincinnati, Ohio, 45241

  • Louis Stokes Clvlnd VA Med Ctr

    Cleveland, Ohio, 44106

  • MetroHealth Medical Center

    Cleveland, Ohio, 44109

  • Cleveland Clinic_Cleveland

    Cleveland, Ohio, 44195

  • MedStar Hlth Res Institute

    Clinton, Maryland, 20735

  • Missouri Cardiovascular Specialist

    Columbia, Missouri, 65201

  • Valley Clinical Trials

    Covina, California, 91723

  • Liver Ins@ Mthdist DTX Med Cen

    Dallas, Texas, 75203

  • Dallas VA Medical Center

    Dallas, Texas, 75216

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390-9302

  • Danbury Hospital - Cardiology Department

    Danbury, Connecticut, 06810

  • Geisinger Medical Center

    Danville, Pennsylvania, 17822

  • Atlanta VAMC

    Decatur, Georgia, 30033

  • Denver Health Medical Center

    Denver, Colorado, 80204

  • Wayne State University/University Health Center

    Detroit, Michigan, 48201

  • Essentia Health

    Duluth, Minnesota, 55805

  • Duke University Medical Center

    Durham, North Carolina, 27710

  • Saint Elizabeth Medical Center

    Edgewood, Kentucky, 41017

  • Midwest Cardiovascu Rsrch Foundation

    Elkhart, Indiana, 46514

  • University Hospitals Of Cleveland Medical Center

    Elyria, Ohio, 44035

  • Endeavor Health Glenbook Hosp

    Evanston, Illinois, 60201

  • Wright State University

    Fairborn, Ohio, 45324

  • Eastern Shore Rsrch Inst, LLC

    Fairhope, Alabama, 36532

  • Inova Fairfax Medical Campus

    Falls Church, Virginia, 22042

  • Sanford Health - Fargo

    Fargo, North Dakota, 58102

  • Holy Cross Hospital

    Fort Lauderdale, Florida, 33308

  • University of Florida

    Gainesville, Florida, 32608

  • Northeast Georgia Medical Ctr

    Gainesville, Georgia, 30501

  • University of Texas Medical Branch

    Galveston, Texas, 77555

  • Mercy Gilbert Medical Center

    Gilbert, Arizona, 85297

  • Colorado Heart and Vascular PC

    Golden, Colorado, 80401

  • Moses H. Cone Mem Hosp

    Greensboro, North Carolina, 27401

  • Prism Hlth Carolina Card Cons

    Greenville, South Carolina, 29605

  • Hackensack Meridian Health - Cardiovascular

    Hackensack, New Jersey, 07601

  • The Heart House Haddon Heights

    Haddon Heights, New Jersey, 08035

  • Penn State Hershey Medical Center

    Hershey, Pennsylvania, 17033

  • Wake Forest Uni Hlth Sciences

    High Point, North Carolina, 27262

  • Memorial Healthcare

    Hollywood, Florida, 33021

  • Houston Medical Center

    Houston, Texas, 77004

  • Houston Methodist Hospital

    Houston, Texas, 77030

  • Texas Heart Inst Medical Ctr

    Houston, Texas, 77030

  • UT Health University of Texas

    Houston, Texas, 77030

  • Prolato Clinical Research Cntr

    Houston, Texas, 77054

  • Heart Center Rsrch_Hunstville

    Huntsville, Alabama, 35801

  • Indiana University Health Methodist Hospital

    Indianapolis, Indiana, 46202

  • Jackson Heart Clinic

    Jackson, Mississippi, 39216

  • Univ of Mississippi Med Center

    Jackson, Mississippi, 39216

  • UF Hlth Jacksonville

    Jacksonville, Florida, 32209

  • Mayo Clinic Jacksonville

    Jacksonville, Florida, 32224

  • Baptist Heart Specialists

    Jacksonville, Florida, 32258

  • Jersey City Medical Center

    Jersey City, New Jersey, 07302

  • WMU Homer Stryker MD School of Medicine

    Kalamazoo, Michigan, 49008

  • University Of Kansas Hospital

    Kansas City, Kansas, 66160

  • Kettering Medical Center

    Kettering, Ohio, 45429

  • Knoxville Heart Group

    Knoxville, Tennessee, 37916

  • Tennova HC Turkey Creek MC

    Knoxville, Tennessee, 37934

  • UCSD Medical Center

    La Jolla, California, 92037

  • McLaren Greater Lansing

    Lansing, Michigan, 48910

  • UMC of Southern Nevada

    Las Vegas, Nevada, 89102

  • Dartmouth-Hitchcock Med Ctr

    Lebanon, New Hampshire, 03766

  • Arkansas Cardiology Clinic

    Little Rock, Arkansas, 72205

  • Central Arkansas Veteran's Healthcare System

    Little Rock, Arkansas, 72205

  • S Denver Cardiology Associates

    Littleton, Colorado, 80120

  • Saint Joseph's Hospital Health Center

    Liverpool, New York, 13088

  • Loma Linda University Faculty Medical Clinics

    Loma Linda, California, 92354

  • VAGrtrLosAngelesHlthcareSystem

    Los Angeles, California, 90073

  • University of Californ LA-UCLA

    Los Angeles, California, 90095

  • University Of Louisville

    Louisville, Kentucky, 40202

  • Fairview Health Services

    Maplewood, Minnesota, 55109

  • HCA Research Institute

    McAllen, Texas, 78503-1299

  • Baptist Clin Res Institute

    Memphis, Tennessee, 38120

  • St. Luke's Idaho Cardiology Associates

    Meridian, Idaho, 83642

  • MidMic Medical Cntr - Midland

    Midland, Michigan, 48670

  • Aurora St. Luke's Medi Ctr

    Milwaukee, Wisconsin, 53215

  • Abbott Northwestern Hospital

    Minneapolis, Minnesota, 55407

  • VA Medical Center_Minneapolis

    Minneapolis, Minnesota, 55417

  • Trinity Medical Group

    Minot, North Dakota, 58701

  • Mobile Heart USA Health Cardiology Clinic

    Mobile, Alabama, 36606

  • McLaren Macomb Health Care

    Mount Clemens, Michigan, 48043

  • Heart & Vascular Inst._Titus

    Mount Pleasant, Texas, 75455

  • Inspira Health - Cardiology

    Mullica Hill, New Jersey, 08062

  • Intermountain Medical Center

    Murray, Utah, 84107-5701

  • Saint Thomas Hospital

    Nashville, Tennessee, 37205

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232

  • Yale Ctr for Clin Invest

    New Haven, Connecticut, 06519

  • University Medical Center New Orleans

    New Orleans, Louisiana, 70112

  • NYU Grossman School of Med

    New York, New York, 10016

  • Mount Sinai Morningside

    New York, New York, 10025

  • Christiana Care Health Services, Inc.

    Newark, Delaware, 19718

  • Sentara Bayside Hospital

    Norfolk, Virginia, 23507

  • North Kansas City Hospital

    North Kansas City, Missouri, 64116

  • Parkway Cardiology Associates, PC

    Oak Ridge, Tennessee, 37830

  • South Oklahoma Heart Research, LLC

    Oklahoma City, Oklahoma, 73135

  • Methodist Physicians Clinic

    Omaha, Nebraska, 681114

  • University Of California Irvine

    Orange, California, 92868-3201

  • Midwest Heart and Vascular Specialists

    Overland Park, Kansas, 66211

  • Baptist Hospital Cardiology

    Pensacola, Florida, 32503

  • Ascension Sacred Heart

    Pensacola, Florida, 32504

  • McLaren Northern MI Hosp

    Petoskey, Michigan, 49770

  • Mayo Clinic Arizona

    Phoenix, Arizona, 85054

  • Baylor Scott & White Res Inst

    Plano, Texas, 75093

  • AtlantiCare Regional Medical Center

    Pomona, New Jersey, 08240

  • Trinity Health Oakland Hospital

    Pontiac, Michigan, 48341

  • Maine Medical Center Bramhall

    Portland, Maine, 04102

  • CV Research of Knoxville

    Powell, Tennessee, 37849

  • Rhode Island Hospital

    Providence, Rhode Island, 02903

  • NC Heart and Vascular Research

    Raleigh, North Carolina, 27697

  • Monument Health Clinical Rsrch

    Rapid City, South Dakota, 57701

  • Reid Physician Associates

    Richmond, Indiana, 47374

  • Chippenham Medical Center

    Richmond, Virginia, 23225

  • Bon Secours St. Mary's Hospital of Richmond, LLC

    Richmond, Virginia, 23226

  • McGuire VA Medical Center

    Richmond, Virginia, 23249

  • Virginia Commonwealth University Health System

    Richmond, Virginia, 23298

  • University of Rochester

    Rochester, New York, 14642

  • OSF HealthCare_Cardiovasc Inst

    Rockford, Illinois, 61107

  • Adventist HealthCare Shady Grove Medical Center

    Rockville, Maryland, 20850

  • St Francis Hospital Lindner Research Center

    Roslyn, New York, 11576

  • Corewell Health

    Royal Oak, Michigan, 48073

  • Regions Hospital

    Saint Paul, Minnesota, 55101

  • VA Medical Center_Salem

    Salem, Virginia, 24153-6404

  • Methodist Healthcare System of San Antonio

    San Antonio, Texas, 78229

  • Kaiser Permanente Viewridge Medical Offices

    San Diego, California, 92123

  • San Diego Cardiac Center

    San Diego, California, 92123

  • San Francisco V.A. Medical Center

    San Francisco, California, 94121

  • Intercoastal Medical Group

    Sarasota, Florida, 34232

  • Robert Packer Hospital

    Sayre, Pennsylvania, 18840

  • Honor Health

    Scottsdale, Arizona, 85258

  • Swedish Medical Center_Seattle

    Seattle, Washington, 98122-5789

  • University Of Washington_Seattle

    Seattle, Washington, 98195

  • Overton Brooks V.A. Medical Center

    Shreveport, Louisiana, 71101-4295

  • Jadestone Clinical Research, LLC

    Silver Spring, Maryland, 20904

  • Sanford Research

    Sioux Falls, South Dakota, 57105

  • Ascension St. Mary's Research Institute - Michigan

    Southfield, Michigan, 48075

  • Prairie Cardiovascular Consultants, Ltd.

    Springfield, Illinois, 62701

  • Mercy Research

    Springfield, Missouri, 65804

  • Washington University School of Medicine_St. Louis

    St Louis, Missouri, 63110

  • Cardiology Associates of Fairfield County

    Stamford, Connecticut, 06905

  • Stony Brook University Hospital

    Stony Brook, New York, 11794

  • Multicare Health System

    Tacoma, Washington, 98405

  • Holy Name Medical Center

    Teaneck, New Jersey, 07666

  • Jacobi Medical Center

    The Bronx, New York, 10461

  • Cardio. Consult. of S. GA

    Thomasville, Georgia, 31792

  • Advanced Heart & Vein Center

    Thornton, Colorado, 80023

  • ProMedica

    Toledo, Ohio, 43606

  • Mercy Health - St. Vincent Medical Center

    Toledo, Ohio, 43608

  • University of Toledo

    Toledo, Ohio, 43614

  • LA BioMed Harbor UCLA Med Cenr

    Torrance, California, 90502

  • Torrance Memorial Medical Center

    Torrance, California, 90505

  • Cardiolg Assoc Rsch LLC_Tupelo

    Tupelo, Mississippi, 38801

  • North Mississippi Medical Center

    Tupelo, Mississippi, 38801

  • Christus Heart and Vascular Institute

    Tyler, Texas, 75701

  • Westchester Medical Center

    Valhalla, New York, 10595

  • Heart House - Vineland

    Vineland, New Jersey, 08360

  • MedStar Hlth Res Institute

    Washington D.C., District of Columbia, 20010

  • MercyOne NE Iowa Fam Med & Res

    Waterloo, Iowa, 50702

  • Interventional Cardiology Medical Group

    West Hills, California, 91307

  • Reading Hospital

    West Reading, Pennsylvania, 19611

  • Valley Health Link

    Winchester, Virginia, 22601

  • Novant Hlth Cardio - Kimel Park

    Winston-Salem, North Carolina, 27103

  • Winter Haven Hospital

    Winter Haven, Florida, 33881

  • Trinity Health Michigan Heart

    Ypsilanti, Michigan, 48197

  • Genesis Health Care System

    Zanesville, Ohio, 43701

Other trials in United States

India58 sites

  • Sardar Vallabhbhai Patel Institute of Medical Sciences and Research

    Ahmedabad, Gujarat, 380006

  • Marengo CIMS Hospital

    Ahmedabad, Gujarat, 380060

  • Jawaharlal Nehru Medical College and Hospital

    Aligarh, Uttar Pradesh, 202002

  • Ramaiah Memorial Hospital

    Bengaluru, Karnataka, 560054

  • Sri Jayadeva Institute of Cardiovascular Sciences & Research

    Bengaluru, Karnataka, 560069

  • All India Institute of Medical Sciences (AIIMS), Bhubaneswar

    Bhubaneswar, Odisha, 751019

  • S.P. Medical College & Associated Group of Hospitals

    Bikaner, Rajasthan, 334003

  • Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh

    Chandigarh, 160012

  • The Madras Medical Mission

    Chennai, Tamil Nadu, 600037

  • Sri Ramachandra Medical Centre

    Chennai, Tamil Nadu, 600116

  • G. Kuppuswamy Naidu Memorial Hospital

    Coimbatore, Tamil Nadu, 641037

  • SCB Medical College and Hospital

    Cuttack, Odisha, 753007

  • Shri Mahant Indiresh Hospital

    Dehradun, Uttarakhand, 248001

  • Lalitha PVS Institute of Medical Sciences

    Guntur, Andhra Pradesh, 522001

  • Osmania General Hospital

    Hyderabad, Telangana, 500012

  • ESIC Medical College and Hospital, Hyderabad

    Hyderabad, Telangana, 500038

  • Malla Reddy Narayana Multispeciality Hospital

    Hyderabad, Telangana, 500055

  • SMS Medical College & Attached Hospitals

    Jaipur, Rajasthan, 302004

  • Ganesh Shankar Vidyarthe Memorial (GSVM) Medical College

    Kanpur, Uttar Pradesh, 208002

  • Lisie Hospital

    Kochi, Kerala, 682018

  • B M Birla Heart Research Centre

    Kolkata, West Bengal, 700027

  • Apollo Multispeciality Hospital, Kolkata

    Kolkata, West Bengal, 700054

  • Medical College & Hospital, Kolkata

    Kolkata, West Bengal, 700073

  • Nil Ratan Sircar Medical College and Hospital

    Kolkata, West, 700014

  • King George's Medical University (KGMU)

    Lucknow, Uttar Pradesh, 226003

  • Dr. Ram Manohar Lohia Institute of Medical Sciences

    Lucknow, Uttar Pradesh, 226010

  • Sanjay Gandhi Postgraduate Institute of Medical Sciences

    Lucknow, Uttar Pradesh, 226014

  • Dayanand Medical College & Hospital

    Ludhiana, Punjab, 141001

  • Justice K S Hegde Charitable Hospital

    Mangaluru, Karnataka, 575018

  • Fortis Hospital, Mohali

    Mohali, Punjab, 160062

  • Seth GS Medical College & KEM Hospital

    Mumbai, Maharashtra, 400012

  • Arneja Heart & Multispeciality Hospital

    Nagpur, Maharashtra, 440010

  • Shri Krishna Hrudayalaya & Critical Care Centre

    Nagpur, Maharashtra, 440012

  • Central India Cardiology Hospital and Research Institute

    Nagpur, Maharashtra, 440015

  • All India Institute of Medical Sciences (AIIMS), Nagpur

    Nagpur, Maharashtra, 441108

  • Chopda Medicare and Research Centre Pvt. Ltd.

    Nashik, Maharashtra, 422005

  • Vijan Hospital & Research Centre

    Nashik, Maharashtra, 422005

  • Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital

    New Delhi, National Capital Territory of Delhi, 110001

  • G B Pant Institute of Postgraduate Medical Education and Research

    New Delhi, National Capital Territory of Delhi, 110002

  • Max Super Speciality Hospital, Saket

    New Delhi, National Capital Territory of Delhi, 110017

  • Fortis Escorts Heart Institute, New Delhi

    New Delhi, National Capital Territory of Delhi, 110025

  • All India Institute of Medical Sciences (AIIMS)

    New Delhi, National Capital Territory of Delhi, 110029

  • Vardhaman Mahavir Medical College & Safdarjung Hospital

    New Delhi, National Capital Territory of Delhi, 110029

  • Sir Ganga Ram Hospital

    New Delhi, National Capital Territory of Delhi, 110060

  • Batra Hospital and Medical Research Center

    New Delhi, National Capital Territory of Delhi, 110062

  • Indraprastha Apollo Hospital, New Delhi

    New Delhi, National Capital Territory of Delhi, 110076

  • Aakash Healthcare Super Speciality Hospital

    New Delhi, 110075

  • Lakshmi Hospital

    Palakkad, Kerala, 678013

  • Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)

    Puducherry, Tamil Nadu, 605006

  • Deenanath Mangeshkar Hospital & Research Centre

    Pune, Maharashtra, 411004

  • Sahyadri Super Speciality Hospital

    Pune, Maharashtra, 411004

  • SMC Heart Institute and IVF Research Centre

    Raipur, Chhattisgarh, 492007

  • Shri B. D. Mehta Mahavir Heart Institute

    Surat, Gujarat, 395001

  • Kasturba Medical College and Hospital, Manipal

    Udupi, Karnataka, 576104

  • Sterling Hospitals, Race Course Road

    Vadodara, Gujarat, 390 007

  • Rhythm Heart Institute

    Vadodara, Gujarat, 390022

  • King George Hospital

    Visakhapatnam, Andhra Pradesh, 530002

  • Medicover Hospitals, Visakhapatnam MVP

    Visakhapatnam, Andhra Pradesh, 530017

Other trials in India

Poland53 sites

  • Wojewodzki Szpital Specjalistyczny W Bialej Podlaskiej

    Biała Podlaska, 21-500

  • Uniwersytecki Szpital Kliniczny w Bialymstoku

    Bialystok, 15-276

  • American Heart of Poland S.A.

    Bielsko-Biala, 43-316

  • Szpital Uniwersytecki Nr 2 im. Dr. Jana Biziela

    Bydgoszcz, 85-168

  • 10 Wojskowy Szpital Kliniczny z Poliklinika - Samodzielny Publiczny Zaklad Opieki Zdrowotnej w Bydgoszczy

    Bydgoszcz, 85-681

  • American Heart of Poland S.A.

    Chrzanów, Lesser Poland Voivodeship, 32-500

  • Wojewodzki Szpital Specjalistyczny im. NMP w Czestochowie

    Częstochowa, 42-202

  • SCANMED Spółka Akcyjna

    Częstochowa, 42-217

  • American Heart of Poland S.A.

    Dąbrowa Górnicza, Silesian Voivodeship, 41-300

  • Wojewodzki Szpital Zespolony W Elblagu samodzielny publiczny zakład opieki zdrowotnej

    Elblag, 82-300

  • Uniwersyteckie Centrum Kliniczne (UCK)

    Gdansk, 80-214

  • Copernicus Podmiot Leczniczy Sp. z o.o.

    Gdansk, 80-462

  • Szpitale Pomorskie Sp. z o.o.

    Gdynia, Pomeranian Voivodeship, 81-348

  • Szpital Miejski Nr 4 w Gliwicach Sp. z o.o., Oddzial Kardiologii

    Gliwice, Silesian Voivodeship, 44-100

  • Samodzielny Publiczny Specjalistyczny Szpital Zachodni Im.Sw.Jana Pawla II

    Grodzisk Mazowiecki, 05-825

  • American Heart of Poland S.A.

    Kędzierzyn-Koźle, 47-200

  • SCANMED Spółka Akcyjna

    Kluczbork, 46-200

  • Wojewodzki Szpital Zespolony im. dr. Romana Ostrzyckiego w Koninie

    Konin, 62-504

  • Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki w Krakowie

    Krakow, 30-688

  • Intercard Spolka z ograniczona odpowiedzialnoscia

    Krosno, 38-400

  • SCANMED Spółka Akcyjna

    Kutno, 99-300

  • Uniwersytecki Szpital Kliniczny nr 2 Uniwersytetu Medycznego w Lodzi

    Lodz, 90-549

  • Uniwersytecki Szpital Kliniczny nr 2 Uniwersytetu Medycznego w Łodzi

    Lodz, 90-549

  • Wojewódzki Specjalistyczny Szpital im.Wl. Bieganskiego,

    Lodz, 91-347

  • Miedziowe Centrum Zdrowia s.a.

    Lubin, 59301

  • 1 Wojskowy Szpital Kliniczny z Poliklinika SPZOZ

    Lublin, 20-049

  • Podhalanski Szpital Specjalistyczny

    Nowy Targ, 34-400

  • Uniwersytecki Szpital Kliniczny w Opolu

    Opole, 45-401

  • Samodzielny Publiczny Zespół Zakładów Opieki Zdrowotnej w Ostrowi Mazowieckiej

    Ostrów Mazowiecka, 07-300

  • Zespol Zakladow Opieki Zdrowotnej w Ostrowie Wielkopolskim

    Ostrów Wielkopolski, Greater Poland Voivodeship, 63-400

  • Zespół Zakładów Opieki Zdrowotnej w Ostrowie Wielkopolskim

    Ostrów Wielkopolski, Greater Poland Voivodeship, 63-400

  • Intercard Spolka z Ograniczona Odpowiedzialnoscia

    Pińczów, 28400

  • Uniwersytecki Szpital Kliniczny W Poznaniu

    Poznan, 60-335

  • Uniwersytecki Szpital Kliniczny W Poznaniu

    Poznan, 61-848

  • Wojewodzki Szpital Im. Sw.Ojca Pio W Przemyslu

    Przemyśl, 37-700

  • Samodzielny Publiczny Zaklad Opieki Zdrowotnej W Pulawach

    Puławy, Lublin Voivodeship, 24-100

  • Samodzielny Publiczny Zaklad Opieki Zdrowotnej Ministerstwa Spraw Wewnetrznych i Administracji w Rzeszowie

    Rzeszów, Podkarpackie Voivodeship, 35-111

  • Kliniczny Szpital Wojewodzki nr 2 im. Sw. Jadwigi Krolowej w Rzeszowie

    Rzeszów, Podkarpackie Voivodeship, 35-301

  • Samodzielny Publiczny Zespol Opieki Zdrowotnej w Swidnicy

    Swidnica, 58100

  • Uniwersytecki Szpital Kliniczny Nr 2 PUM W Szczecinie

    Szczecin, 70-111

  • Specjalistyczny Szpital Im. E. Szczeklika W Tarnowie

    Tarnów, 33-100

  • Specjalistyczny Szpital Miejski im. M.Kopernika w Toruniu

    Torun, 87-100

  • American Heart of Poland S.A.

    Tychy, Silesian Voivodeship, 43-100

  • Śródmiejskie Centrum Kliniczne,II Oddział Kardiologii MSB, Klinika Chorób Serca CMKP

    Warsaw, 00-685

  • Szpital Wolski im. dr Anny Gostynskiej Sp. z o.o.

    Warsaw, 01-211

  • Uniwersyteckie Centrum Kliniczne WUM

    Warsaw, 02-097

  • Szpital Grochowski im. dr med. Rafala Masztaka Sp. z o.o.

    Warsaw, 04-073

  • Szpital Grochowski im. dr med. Rafała Masztaka Sp. z o.o.

    Warsaw, 04-073

  • Narodowy Instytut Kardiologii Stefana Kardynala Wyszynskiego Panstwowy Instytut Badawczy

    Warsaw, 04-628

  • 4 Wojskowy Szpital Kliniczny Z Poliklinika Samodzielny Publiczny Zaklad Opieki Zdrowotnej We Wroclawiu

    Wroclaw, Lower Silesian Voivodeship, 50-981

  • Wojewodzki Szpital Specjalistyczny We Wroclawiu

    Wroclaw, 51-124

  • Dolnoslaski Szpital Specjalistyczny Im. T.Marciniaka-Centrum Medycyny Ratunkowej

    Wroclaw, 54-049

  • American Heart Of Poland S.A.

    Zgierz, 95100

Other trials in Poland

China45 sites

  • Beijing Anzhen Hospital, Capital Medical University

    Beijing, Beijing Municipality, 100029

  • China-Japan Friendship Hospital

    Beijing, Beijing Municipality, 100029

  • Peking University First Hospital-Cardiology

    Beijing, Beijing Municipality, 100034

  • Chinese Academy of Medical Sciences Fuwai Hospital

    Beijing, Beijing Municipality, 100037

  • Peking University Third Hospital

    Beijing, Beijing Municipality, 100191

  • Cangzhou Central Hospital

    Cangzhou, Hebei, 061001

  • China-Japan Union Hospital of Jilin University-Cardiology

    Changchun, Jilin, 130033

  • China-Japan Union Hospital of Jilin University

    Changchun, Jilin, 130033

  • Xiangya Hospital Central-South University

    Changsha, Hunan, 410008

  • The Second Xiangya Hospital of Central South University

    Changsha, Hunan, 410011

  • West China Hospital Sichuan University-Cardiology

    Chengdu, Sichuan, 610044

  • Sichuan Academy of Medical Science & Sichuan Provincial People's Hospital; Affiliated Hospital of UESTC-Cardiology

    Chengdu, Sichuan, 610072

  • The Second Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, 400060

  • The First Affiliated Hospital of Fujian Medical University

    Fuzhou, Fujian, 350005

  • Guangdong Provincial People's Hospital

    Guangzhou, Guangdong, 510080

  • Nanfang Hospital, Southern Medical University

    Guangzhou, Guangdong, 510515

  • Nanfang Hospital, Southern Medical University

    Guangzhou, 510515

  • Sir Run Run Shaw Hospital, Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310009

  • Zhejiang Hospital-Cardiology

    Hangzhou, Zhejiang, 310030

  • Sir Run Run Shaw Hospital, Zhejiang University School of Medicine

    Hangzhou, 310009

  • Zhejiang Hospital, Zhejiang University School of Medicine

    Hangzhou, 310030

  • The First Affiliated Hospital of Harbin Medical University

    Harbin, Heilongjiang, 150001

  • The First Affiliated Hospital of Harbin Medical University

    Harbin, 150001

  • Jinan Central Hospital

    Jinan, Shandong, 250013

  • Nanjing Drum Tower Hospital

    Nanjing, Jiangsu, 210008

  • Zhongda Hospital Southeast University

    Nanjing, Jiangsu, 210009

  • The Second Affiliated Hospital of Nanjing Medical University

    Nanjing, Jiangsu, 210011

  • Zhongda Hospital, Southeast University

    Nanjing, 210009

  • The People's Hospital of Guangxi Zhuang Autonomous Region

    Nanning, Guangxi, 530021

  • Zhongshan Hospital, Fudan University-Cardiology

    Shanghai, Shanghai Municipality, 200032

  • Huashan Hospital Fudan University

    Shanghai, Shanghai Municipality, 200040

  • The People's Hospital of Liaoning Province-Cardiology

    Shenyang, Liaoning, 110016

  • The People's Hospital of Liaoning Province

    Shenyang, Liaoning, 110016

  • Shengjing Hospital of China Medical University-Cardiology

    Shenyang, Liaoning, 110136

  • Shengjing Hospital of China Medical University

    Shenyang, 110136

  • Hebei General Hospital

    Shijiazhuang, Hebei, 050051

  • Tianjin Medical University General Hospital-Endocrinology

    Tianjin, Tianjin Municipality, 300052

  • Tianjin People's Hospital

    Tianjin, Tianjin Municipality, 300122

  • TEDA International Cardiovascular Hospital-Cardiovascular

    Tianjin, Tianjin Municipality, 300457

  • TEDA International Cardiovascular Hospital

    Tianjin, Tianjin Municipality, 300457

  • The 1st Affiliated Hospital of WMU-Cardiology

    Wenzhou, Zhejiang, 325000

  • The First Affiliated Hospital of WMU-Cardiology

    Wenzhou, Zhejiang, 325000

  • Union Hospital Tongji Medical College Huazhong University of Science and Technology-Cardiology

    Wuhan, Hubei, 430022

  • Renmin Hospital of Wuhan University-Cardiology

    Wuhan, Hubei, 430060

  • The First Affiliated Hospital of Xi'an JiaoTong University-Cardiovascular

    Xi'an, Shaanxi, 710061

Other trials in China

Italy40 sites

  • Ente Ecclesiastico Ospedale Generale Regionale Miulli - Cardiologia e UTIC

    Acquaviva delle Fonti, 70021

  • Azienda Ospedaliero-Universitaria SS Antonio e Biagio e Cesare Arrigo

    Alessandria, 15121

  • Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII

    Bergamo, Lombardy, 24127

  • Ospedale Maggiore Carlo Alberto Pizzardi

    Bologna, 40133

  • AORN "Sant'Anna e San Sebastiano"

    Caserta, Ce, 81100

  • Azienda Ospedaliero-Universitaria Renato Dulbecco

    Catanzaro, 88100

  • Ss. Annunziata

    Chieti, Abruzzo, 66100

  • A.O.U. Ferrara, Sant'Anna

    Cona (Ferrara), Fe, 44124

  • Ospedale Civile dell'Annunziata

    Cosenza, 87100

  • Azienda Ospedaliera Universitaria Careggi

    Florence, 50134

  • Ospedale Policlinico San Martino

    Genova, 16132

  • AUSL Toscana Sud Est - Ospedale Misericordia Grosseto

    Grosseto, 58100

  • Ospedale Sant'Andrea - UOC Cardiologia

    La Spezia, 19124

  • ICOT Istituto Marco Pasquali - UOC Cardiologia

    Latina, Lazio, 04100

  • ICOT Istituto Marco Pasquali - UOC Cardiologia

    Latina, 04100

  • Grande Ospedale Metropolitano Niguarda

    Milan, 20162

  • Fondazione IRCCS San Gerardo dei Tintori

    Monza, 20900

  • Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli

    Naples, 80131

  • Azienda Ospedaliera Universitaria Federico II di Napoli

    Naples, 80131

  • AOU Maggiore della Carità di Novara - Dipartimento Toraco-Cardio-Vascolare - SCDU Cardiologia

    Novara, 28100

  • Azienda Ospedaliero-Universitaria Maggiore della Carità di Novara

    Novara, 28100

  • Azienda Ospedaliera di Parma

    Parma, 43126

  • Fondazione IRCCS Policlinico San Matteo

    Pavia, 27100

  • Azienda Unità Sanitaria Locale Di Piacenza - Cardiologia

    Piacenza, 29121

  • Azienda Ospedaliera Santa Maria Degli Angeli

    Pordenone, PN, 33170

  • Azienda Sanitaria Friuli Occidentale - Azienda Ospedaliera Santa Maria Degli Angeli - SC Cardiologia Pordenone

    Pordenone, PN, 33170

  • Arcispedale S Maria Nuova Azienda ULSS-IRCCS

    Reggio Emilia, 42123

  • AUSL Romagna - Distretto Rimini - Ospedale Infermi

    Rimini, 47923

  • Presidio Ospedaliero di Rivoli

    Rivoli, To, 10098

  • Ospedale Sandro Pertini - UOC Cardiologia

    Rome, 00157

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    Rome, 00168

  • Fondazione Policlinico Universitario Agostino Gemelli IRCS

    Rome, 00168

  • Policlinico Casilino - Cardiologia e UTIC

    Rome, 00169

  • Ospedale Isola Tiberina Gemelli Isola

    Rome, 00186

  • Azienda Ospedaliero - Universitaria Sant'Andrea

    Rome, 00189

  • IRCCS Policlinico San Donato

    San Donato Milanese, MI, 20097

  • Azienda Sanitaria Ospedaliera Ordine Mauriziano SC Cardiologia

    Torino, To, 10128

  • A.O.U Città della Salute e della Scienza di Torino

    Torino, 10126

  • A.O.U Città della Salute e della Scienza di Torino

    Turin, Piedmont, 10126

  • AOUI Verona

    Verona, 37126

Other trials in Italy

Japan39 sites

  • Fujita Health University Hospital_Cardiology

    Aichi, 470-1192

  • Toho University Sakura Medical Center_Cardiology

    Chiba, 285-8741

  • Asahi General Hospital_Cardiology

    Chiba, 289-2511

  • Ehime Prefectural Central Hosp

    Ehime, 790-0024

  • Matsuyama Red Cross Hospital_Department of Cardiovascular Medicine

    Ehime, 790-8524

  • Japanese Red Cross Fukuoka Hospital_Cardiology

    Fukuoka, 815-8555

  • St.Mary's Hospital_Cardiology & Cardiovascular Disease Management

    Fukuoka, 830-8543

  • Fukuoka University Hospital_Cardiology

    Fukuoka-shi, Fukuoka, 814-0133

  • Hyogo Prefectural HarimaHimeji General Medical Center_Cardiology

    Himeji-shi, Hyogo, 670-8560

  • Hanaoka Seishu Memorial Hosp._Cardiovascular Medicine

    Hokkaido, 062-0003

  • Hanaoka Seishu Memorial Hospital

    Hokkaido, 062-0003

  • Nishinomiya Watanabe Cardiovascular Cerebral Center_Cardiovascular Medicine

    Hyōgo, 662-0911

  • Hyogo Medical University Hospital_Cardiovascular Medicine

    Hyōgo, 663-8501

  • Tsuchiura Kyodo General Hospital_Internal Medicine

    Ibaraki, 300-0028

  • Mito Saiseikai General Hospital_Cardiology

    Ibaraki, 311-4198

  • Ishikawa Prefectural Central Hospital_Cardiology

    Ishikawa, 920-8530

  • Kanto Rosai Hospital_Cardiology

    Kanagawa, 211-8510

  • Yokohama Municipal Citizen's Hospital_Cardiology

    Kanagawa, 221-0855

  • Saiseikai Yokohamashi Tobu Hospital_Cardiology

    Kanagawa, 230-8765

  • Yokohama City University Medical Center_Cardiovascular Center

    Kanagawa, 232-0024

  • Yokohama City University Hospital

    Kanagawa, 236-0004

  • Tokai University Hospital_Cardiology

    Kanagawa, 259-1193

  • National Hospital Organization Kumamoto Medical Center_Cardiology

    Kumamoto, 860-0008

  • NHO Kure Medical Center and Chugoku Cancer Center_Cardiology

    Kure-shi, Hiroshima, 737-0023

  • NHO Kure Medical Center and Chugoku Cancer Center

    Kure-shi, Hiroshima, 737-0023

  • Miyazaki Medical Association Hospital_Cardiology

    Miyazaki, Miyazaki, 880-2102

  • Miyazaki Medical Association Hospital

    Miyazaki, Miyazaki, 880-2102

  • The Sakakibara Heart Institute of Okayama_Department of Cardiovascular Medicine

    Okayama, 700-0804

  • Osaka General Medical Center_Cardiology

    Osaka, 558-8558

  • Ishikiriseiki Hospital_Circulatory Medicine

    Osaka, 579-8026

  • Tohoku University Hospital, Cardiovascular

    Sendai-shi, Miyagi, 980-8574

  • Shiga University of Medical Science Hospital_Cardiology

    Shiga, 520-2192

  • Juntendo University Shizuoka Hospital_Gastroenterology & Hepatology

    Shizuoka, 410-2295

  • Juntendo University Shizuoka Hospital

    Shizuoka, 410-2295

  • Kagawa Prefectural Central Hospital_Cardiovascular Medicine

    Takamatsu-shi, Kagawa, 760-8557

  • Tokushima Prefectural Central Hospital_Cardiology

    Tokushima, 770-8539

  • Teikyo University Hospital_Cardiology

    Tokyo, 173-8606

  • Tsukuba Medical Center Hospital_Department of Cardiology

    Tsukuba-shi, Ibaraki, 305-8558

  • Saiseikai Yokohamashi Nanbu Hospital_Cardiology

    Yokohama-shi, Kanagawa, 234-0054

Other trials in Japan

Bulgaria36 sites

  • MHAT Puls AD, Cardiology Department

    Blagoevgrad, 2700

  • MHAT Heart and Brain EAD - Burgas, Cardiology

    Burgas, 8000

  • UMHAT - Burgas AD

    Burgas, 8000

  • UMHAT Deva Maria EOOD

    Burgas, 8127

  • MHAT Dr. Tota Venkova AD

    Gabrovo, 5300

  • Multiprofile Hospital For Active Treatment Dr. Tota Venkova AD

    Gabrovo, 5300

  • MHAT - Ivan Skenderov EOOD

    Gotse Delchev, 2900

  • MHAT Haskovo AD

    Haskovo, 6300

  • MHAT - Dr. Atanas Dafovski AD, Cardiology department

    Kardzhali, 6600

  • MHAT - Cardiolife OOD - Lovech

    Lovech, 5500

  • MHAT - City Clinic - Sveti Georgi EOOD

    Montana, 3400

  • MHAT - Pazardzhik AD

    Pazardzhik, 4401

  • MHAT Heart and Brain EAD - Pleven, Cardiology

    Pleven, 5804

  • UMHAT Pulmed OOD - Plovdiv, Department of Cardiology

    Plovdiv, 4002

  • UMHAT Sveti Georgi EAD, Plovdiv, Clinic of Cardiology

    Plovdiv, 4002

  • MHAT MC-Sv Ivan Rilski EOOD

    Plovdiv, 4003

  • MHAT Sveta Karidad EAD

    Plovdiv, 4004

  • SHATC - Medica Kor EAD

    Rousse, 7013

  • MHAT Southwest Hospital OOD, Cardiology Department

    Sandanski, 2800

  • MHAT Hadzhi Dimitar OOD

    Sliven, 8800

  • MHAT "Dr. Bratan Shukerov"

    Smolyan, 4700

  • MHAT Dr. Bratan Shukerov

    Smolyan, 4700

  • MHAT National Cardiology Hospital EAD

    Sofia, 1309

  • Acibadem City Clinic UMHAT Tokuda EAD, Cardiology

    Sofia, 1407

  • Acibadem City Clinic UMHAT EOOD, Cardiology

    Sofia, 1415

  • UMHAT Aleksandrovska EAD, Clinic of Cardiology

    Sofia, 1431

  • UMHAT Sveta Ekaterina EAD

    Sofia, 1431

  • UMHATEM N.I. Pirogov EAD

    Sofia, 1606

  • "UMHAT "Sveta Anna" Sofia" AD, Clinic of Cardiology

    Sofia, 1750

  • MHAT Sveta Anna Sofia AD, Clinic of Cardiology

    Sofia, 1750

  • UMHAT Sofiamed EAD

    Sofia, 1797

  • SHATC - Cardiolife OOD - Varna

    Varna, 9009

  • Specialized Hospital For Active Cardiology Treatement Cardiolife OOD

    Varna, 9009

  • UMHAT Sveta Marina EAD, Second Clinic of Cardiology

    Varna, 9010

  • UMHAT "Sveta Marina" EAD

    Varna, 910

  • SHATC - Yambol EAD

    Yambol, 8600

Other trials in Bulgaria

Greece34 sites

  • General Hospital of Athens "Elpis" - Cardiology Department

    Ampelokipoi/Athens, 11522

  • Evangelismos Hospital

    Athens, 10676

  • G.H. of Athens "Evaggelismos"

    Athens, 10676

  • NIMTS Army Share Fund Hospital

    Athens, 115 21

  • Group Euroclinic - Athens Euroclinic - Cardiology Department

    Athens, 11521

  • Henry Dunant Hospital Center

    Athens, 11526

  • "Sotiria" Thoracic Diseases Hospital of Athens

    Athens, 11527

  • 'G. Gennimatas' General Hospital of Athens - Cardiology Department

    Athens, 11527

  • 'G. Gennimatas' General Hospital of Athens

    Athens, 11527

  • Hippokration Hospital

    Athens, 11527

  • Thoracic General Hospital Of Athens I Sotiria - Cardiology Department

    Athens, 11527

  • Alexandra General Hospital, Therapeutic Clinic

    Athens, 11528

  • Konstantopouleio G.H. of Athens, "Agia Olga"

    Athens, 14233

  • "Hygeia" General Hospital of Athens

    Athens, 15123

  • Metropolitan General Hospital Healthcare Facilities Operation And Management Single Member S.A. - Cardiology Clinic

    Athens, 15562

  • Asklepieion General Hospital - Cardiology Clinic

    Athens/Voula, 16673

  • U.G.H of Athens "Attikon"

    Chaidari, Athens, 12462

  • General Hospital of Chios "Skilitsio" - Cardiology Clinic

    Chios, 82100

  • General Hospital Of Eleusina Thriasio - Cardiology Clinic

    Eleusina, 19018

  • General Hospital of Athens "LAIKO"

    Goudi/Athens, 115 27

  • University General Hospital of Ioannina,Internal Medicine

    Ioannina, 455 00

  • University General Hospital of Ioannina,Internal Medicine

    Ioannina, GR-455 00

  • Kat Attica General Hospital - Cardiology Department

    Kifissia, 14561

  • Univ Gen Hospital Larisa, Cardiology Medicine Clinic

    Larissa/Thessaly, Greece, 41110

  • Sismanogleio General Hospital - Cardiology Department

    Marousi, 151 26

  • General Hospital Of Thessaloniki Papageorgiou

    Nea Efkarpia, Thessaloniki, 56429

  • General Hospital Of Patras Agios Andreas - Cardiology Department

    Pátrai, 265 00

  • Geniko Nosokomeio Peiraia Tzaneio - Cardiology department

    Piraeus, 18536

  • Interbalkan Medical Center of Thessaloniki

    Thessaloniki, 546 39

  • "AHEPA" University General Hospital of Thessaloniki

    Thessaloniki, 54636

  • Gen Hospital of Thessaloniki G.Papanikolaou,Cardiology Dpt

    Thessaloniki, 57010

  • Pan-Arcadian General Hospital of Tripoli Evangelistria - Cardiology Department

    Tripoli, 22100

  • General Hospital of Imathia Monada Veria - Cardiology Department

    Véroia, 59132

  • General Hospital of Imathia Monada Veria

    Véroia, 59132

Other trials in Greece

Turkey (Türkiye)34 sites

  • Afyonkarahisar Sağlık Bilimleri Üniversitesi Sağlık Uygulama Ve Araştırma Merkezi- Kardiyoloji

    Afyonkarahisar, 03200

  • Ankara Üniversitesi Tıp Fakültesi İbni Sina Hastanesi- Kardiyoloji

    Ankara, Altindag, 06230

  • Ankara Bilkent Şehir Hastanesi-Kardiyoloji

    Ankara, 06800

  • Ankara Sehir Hastanesi Cardiology

    Ankara, 06800

  • Akdeniz Üniversitesi Hastanesi-Kardiyoloji

    Antalya, 07059

  • Bursa Şehir Hastanesi- Kardiyoloji

    Bursa, 16110

  • Bursa Yüksek İhtisas Eğitim ve Araştırma Merkezi-Kardiyoloji

    Bursa, 16310

  • Trakya Üniversitesi Tıp Fakültesi Hastanesi- Kardiyoloji

    Edirne, 22030

  • Eskişehir Osmangazi Üniversitesi Hastanesi- Kardiyoloji

    Eskişehir, Odunpazari, 26040

  • Istanbul University Cerrahpasa Medical Faculty

    Istanbul, Bakirkoy, 34153

  • İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi Hastanesi- Prof. Dr. Murat Dilmener Yerleşkesi

    Istanbul, Bakirkoy, 34153

  • Cerrahpaşa Kardiyoloji Enstitüsü

    Istanbul, 34098

  • İstanbul Üniversitesi-Cerrahpaşa Kardiyoloji Enstitüsü

    Istanbul, 34098

  • Adana Şehir Eğitim ve Araştırma Hastanesi

    Istanbul, 34335

  • Dr. Siyami Ersek Göğüs Kalp ve Damar Cerrahisi EAH- Kardiyoloji

    Istanbul, 34668

  • Kartal Kosuyolu Yuksek Ihtisas EAH

    Istanbul, 34718

  • Koşuyolu Yüksek İhtisas EAH- Kardiyoloji

    Istanbul, 34718

  • Marmara University Medical Faculty

    Istanbul, 34854

  • Marmara Üniversitesi Pendik EAH- Kardiyoloji

    Istanbul, 34854

  • Erciyes University Cardiology

    Kayseri, 38039

  • Erciyes Üniversitesi Hastanesi- Kardiyoloji

    Kayseri, 38039

  • Kayseri City Hospital

    Kayseri, 38080

  • Kayseri Şehir Hastanesi-Kardiyoloji

    Kayseri, 38080

  • Kocaeli Üniversitesi Hastanesi- Kardiyoloji

    Kocaeli, 41380

  • Necmettin Erbakan University Hospital

    Konya, 42090

  • Necmettin Erbakan Üniversitesi Tıp Fakültesi Hastanesi- Kardiyoloji

    Konya, 42090

  • Kütahya Şehir Hastanesi-Kardiyoloji

    Kütahya, 43100

  • Kütahya Sağlık Bilimleri Üniversitesi Evliya Çelebi EAH- Kardiyoloji

    Merkez/Kütahya, 43040

  • Mersin Şehir Eğitim Araştırma Hastanesi- Kardiyoloji

    Mersin, 33240

  • Mersin Üniversitesi Hastanesi- Kardiyoloji

    Mersin, 33343

  • Antalya Eğitim ve Araştırma Hastanesi- Kardiyoloji

    Muratpasa/ Antalya, 07100

  • Eskişehir Şehir Hastanesi- Kardiyoloji

    Odunpazarı /Eskişehir, 26080

  • Ondokuz Mayıs Üniversitesi Hastanesi- Kardiyoloji

    Samsun, 55100

  • Tokat Gaziosmanpaşa Üniversitesi Tıp Fakültesi Hastanesi- Kardiyoloji

    Tokat Province, 60000

Other trials in Turkey (Türkiye)

Canada32 sites

  • Royal Victoria Regional Health Centre

    Barrie, Ontario, L4M 6M2

  • William Osler Hel Bra Civic Hs

    Brampton, Ontario, L6R 3J7

  • Heritage Medical Research Clinic

    Calgary, Alberta, T2N 4Z6

  • CIUSS Hopit de Chicoutimi

    Chicoutimi, Quebec, G7H 5H6

  • Royal Alexandra Hospital

    Edmonton, Alberta, T5H 3V9

  • Grey Nuns Community Hospital

    Edmonton, Alberta, T6G 2B7

  • Univ of Alberta Hosp Edmonton

    Edmonton, Alberta, T6G 2B7

  • Health Sciences North Rsrch Inst

    Greater Sudbury, Ontario, P3E 5J1

  • QE II Health Sciences Centre

    Halifax, Nova Scotia, B3H 3A7

  • Hamilton Health Sciences Corp, Ontario

    Hamilton, Ontario, L8L 2X2

  • Kelowna Cardiology Res. Ltd.

    Kelowna, British Columbia, V1Y 1T2

  • Kingston General Hospital

    Kingston, Ontario, K7L 2V7

  • London Health Sciences Center Ontario

    London, Ontario, N6A 5A5

  • CHUM Centre de Recherch Hotel-Dieu

    Montreal, Quebec, H2X 0C1

  • Hopital Sacre-Coeur de Montreal

    Montreal, Quebec, H4J 1C5

  • Southlake Regional Hlth Centre

    Newmarket, Ontario, L3Y 2R2

  • University of Ottawa Heart Institute (UOHI)

    Ottawa, Ontario, K1Y 4W7

  • CHU de Quebec-Universite-Laval,HDQ

    Québec, G1R 2J6

  • Ins Uni de Cardi et de PNA de

    Québec, G1V 4G5

  • Regina General Hospital

    Regina, Saskatchewan, S4P 0W5

  • New Brunswick Heart Centre

    Saint John, New Brunswick, E2L 4L2

  • CISSS de Lanaudiere - Centre hospitalier De Lanaudiere

    Saint-Charles-Borromée, Quebec, J6E 6J2

  • Royal University Hospital

    Saskatoon, Saskatchewan, S7N 0W8

  • Niagara Health System

    St. Catharines, Ontario, L2S 0A9

  • CISSSL Hôsp Pierre-Le Gardeur

    Terrebonne, Quebec, J6V 2H2

  • Sunnybrook Health Sciences Centre

    Toronto, Ontario, M4N 3M5

  • St. Michael's Hospital

    Toronto, Ontario, M5B 1W8

  • UHN-Toronto General Hospital

    Toronto, Ontario, M5G 2C4

  • Centre hosp affilié univ rég

    Trois-Rivières, Quebec, G8Z 3R9

  • Vancouver General Hospital

    Vancouver, British Columbia, V5Z 1M9

  • Saint Paul's Hospital

    Vancouver, British Columbia, V6Z 1Y6

  • St. Boniface Hospital

    Winnipeg, Manitoba, R2H 2A6

Other trials in Canada

Germany28 sites

  • Rhön-Klinikum AG - Zentralklinik Bad Berka - Kardiologie

    Bad Berka, 99437

  • Charité - Campus Benjamin Franklin - Klinik für Kardiologie

    Berlin, 12203

  • BG Klinikum Unfallkrankenhaus Berlin GmbH - Klinik für Kardiologie

    Berlin, 12683

  • Uniklinik Klinikum Bielefeld - Kardiologie und Internist. Intensivmedizin

    Bielefeld, 33604

  • Bremer Institut für Herz- und Kreislaufforschung (BIHKF)

    Bremen, 28277

  • Cellitinnen-Krankenhaus St. Vinzenz Köln - Kardiologie

    Cologne, 50733

  • Amper Kliniken AG - Helios Amper-Klinikum Dachau - Kardiologie

    Dachau, 85221

  • Kath. St. Paulus GmbH - St Johannes Hospital Dortmund - Kardiologie

    Dortmund, 44137

  • Städt. Klinikum Dresden - 2. Medizinische Klinik

    Dresden, 01067

  • Uniklinik TU Dresden - Herzzentrum Dresden GmbH

    Dresden, 01307

  • Universitätsklinikum Düsseldorf - Klinik für Kardiologie, Pneumologie und Angiologie

    Düsseldorf, 40225

  • Helios Klinikum Erfurt GmbH - 3. Med. Klinik - Kardiologie

    Erfurt, 99089

  • MVZ CCB Frankfurt und Main-Taunus GbR

    Frankfurt, 60389

  • Universitätsklinikum Frankfurt aM - Kardiologie

    Frankfurt am Main, 60596

  • Universitätsklinikum Freiburg - Medical Center

    Freiburg im Breisgau, 79106

  • Klinikum Friedrichshafen GmbH - Klinik für Kardiologie, Angiologie, Pneumologie und internistische Intensivmedizin

    Friedrichshafen, 88048

  • Klinikum Fulda gAG - Med. Klinik I

    Fulda, 36043

  • Universitätsklinikum Hamburg-Eppendorf - University Medical Center Hamburg-Eppendorf

    Hamburg, 20246

  • Medizinische Hochschule Hannover - Kardiologie und Angiologie

    Hanover, 30625

  • UniklinikHeidelberg - Innere Med. III - Kardiologie, Angiologie, Pneumologie

    Heidelberg, 69120

  • Asklepios Klinik Langen - Medizinische Klinik I

    Langen, 63225

  • Universitätsklinikum Leipzig - Klinik und Poliklinik für Kardiologie

    Leipzig, 04103

  • Klinikum Leverkusen gGmbH - Med. Klinik 1

    Leverkusen, 51375

  • Universitätsklinikum Mannheim - 1. Medizinische Klinik

    Mannheim, 68167

  • Deutsches Herzzentrum TU München - Klinik für Herz- und Kreislauferkrankungen

    München, 80636

  • Uniklinik Regensburg - Innere Medizin II

    Regensburg, 93053

  • Robert-Bosch-Krankenhaus GmbH Stuttgart

    Stuttgart, 70376

  • Uniklinik Tübingen - Innere Med. III Kardiologie und Angiologie

    Tübingen, 72076

Other trials in Germany

United Kingdom27 sites

  • William Harvey Hospital

    Ashford, Kent, TN24 0LZ

  • Blackpool Victoria Hospital

    Blackpool, Lancashire, FY3 8NR

  • Royal Bournemouth Hospital - Cardiology

    Bournemouth, Dorset, BH7 6JH

  • Royal Infirmary of Edinburgh - Cardiology

    Edinburgh, EH16 4SA

  • Golden Jubilee University National Hospital

    Glasgow, G81 4SA

  • Harefield Hospital

    Harefield, Middlesex, UB9 6JH

  • Royal Brompton and Harefield Hospitals

    Harefield, Middlesex, UB9 6JH

  • Kettering General Hospital

    Kettering, NN16 8UZ

  • Glenfield Hospital

    Leicester, LE3 9QP

  • Lincoln County Hospital

    Lincoln, LN2 5QY

  • Liverpool Heart & Chest Hospital

    Liverpool, L14 3PE

  • Barts Heart Centre

    London, EC1A 7BE

  • St Bartholomew's Hospital - Barts Heart Centre

    London, EC1A 7BE

  • King's College Hospital - Cardiology

    London, SE5 9RS

  • Kings College Hospital

    London, SE5 9RS

  • The James Cook University Hospital - Cardiology

    Middlesbrough, TS4 3BW

  • Freeman Hospital, Newcastle

    Newcastle upon Tyne, NE7 7DN

  • Derriford Hospital - Plymouth

    Plymouth, PL6 5FP

  • Queen Alexandra Hospital - Cardiology

    Portsmouth, PO6 3LY

  • Queen Alexandra Hospital

    Portsmouth, PO6 3LY

  • Northern General Hospital

    Sheffield, S5 7AU

  • Lister Hospital

    Stevenage, SG1 4AB

  • Morriston Hospital

    Swansea, SA6 6NL

  • Musgrove Park Hospital

    Taunton, TA1 5DA

  • Torbay Hospital - Cardiology

    Torquay, Devon, TQ2 7AA

  • Royal Cornwall Hospital (Treliske)

    Truro, Cornwall, TR1 3HD

  • New Cross Hospital

    Wolverhampton, WV10 0QP

Other trials in United Kingdom

South Korea26 sites

  • The Catholic University of Korea, Bucheon ST. Mary's Hospital

    Bucheon-si, Gyeonggi-do, 14647

  • Inje University Haeundae Paik Hospital

    Busan, 48108

  • Chungbuk National University Hospital

    Cheongju-si, 28644

  • Kyungpook National University Hospital

    Daegu, 41944

  • Keimyung University Dongsan Hospital

    Daegu, 42601

  • Chungnam National University Hospital

    Daejeon, 35015

  • Wonju Severance Christian Hospital

    Gangwon-do, 26426

  • MyongJi Hospital

    Goyang-si, Gyeonggi-do, 10475

  • Chonnam National University Hospital

    Gwangju, 61469

  • Gachon University Gil Medical Center

    Incheon, 21565

  • Inha University Hospital

    Incheon, 22332

  • Chungnam National University Sejong Hospital

    Sejong-si, 30099

  • Seoul National University Bundang Hospital

    Seongnam-si, Gyeonggi-do, 13620

  • Kyunghee University Medical Center

    Seoul, 02447

  • Korea University Anam Hospital

    Seoul, 02841

  • Seoul National University Hospital

    Seoul, 03080

  • Severance Hospital, Yonsei University Health System

    Seoul, 03722

  • Hanyang university seoul hospital

    Seoul, 04763

  • Kyung Hee University Hospital at Gangdong

    Seoul, 05278

  • Asan Medical Center

    Seoul, 05505

  • The Catholic University of Korea, Seoul ST. Mary's Hospital

    Seoul, 06591

  • Ewha Womans University Seoul Hospital

    Seoul, 07804

  • Korea University Guro Hospital

    Seoul, 08308

  • Ajou University Hospital

    Suwon, Gyeonggi-do, 16499

  • Pusan National University Yangsan Hospital

    Yangsan, Gyeongsangnam-do, 50612

  • Pusan National University Yangsan Hospital

    Yangsan, 50612

Other trials in South Korea

Australia25 sites

  • Royal Adelaide Hospital - Cardiology Department

    Adelaide, South Australia, 5000

  • Royal Adelaide Hospital Cardiovascular Clinical Trials

    Adelaide, South Australia, 5000

  • Flinders Medical Centre

    Bedford Park, South Australia, 5042

  • Sunshine Coast University Hospital - Clinical Research Unit

    Birtinya, Queensland, 4575

  • Royal Brisbane and Women's Hospital

    Brisbane, Queensland, 4029

  • The Prince Charles Hospital

    Brisbane, Queensland, 4032

  • Cairns Base Hospital

    Cairns, Queensland, 4870

  • The Prince Charles Hospital - Cardiology Clinical Research Centre

    Chermside, Queensland, 4032

  • Concord Repatriation General Hospital - Cardiology Department

    Concord, New South Wales, 2139

  • Townsville University Hospital

    Douglas, Queensland, 4814

  • Lyell McEwin Hospital

    Elizabeth Vale, South Australia, 5112

  • Northern Health

    Epping, Victoria, 3076

  • Peninsula University Hospital - Cardiology Department

    Frankston, Victoria, 3199

  • Adrian Costa Clinical Trials Centre

    Geelong, Victoria, 3220

  • Austin Hospital

    Heidelberg, Victoria, 3084

  • Nepean Hospital

    Kingswood, New South Wales, 2747

  • Liverpool Hospital

    Liverpool, New South Wales, 2170

  • Royal Perth Hospital

    Perth, Western Australia, 6000

  • Prince of Wales Hospital - Sydney

    Randwick, New South Wales, 2031

  • The Alfred - Endocrinology & Diabetes Department

    South Yarra, Victoria, 3004

  • Gold Coast University Hospital - Cardiology Department

    Southport, Queensland, 4215

  • Gold Coast University Hosptial

    Southport, Queensland, 4215

  • Sunshine Hospital - Western Centre for Health Research and Education

    St Albans, Victoria, 3021

  • Illawarra Heart Health Centre

    Wollongong, New South Wales, 2500

  • Princess Alexandra Hospital

    Woolloongabba, Queensland, 4102

Other trials in Australia

Spain24 sites

  • Complejo Hospitalario Universitario A Coruña

    A Coruña, 15006

  • Hospital General Universitario Dr. Balmis

    Alicante, 03010

  • Hospital Gral Alicante Dr. Balmis

    Alicante, 03010

  • Hospital Germans Trias i Pujol

    Badalona, Barcelona, 08916

  • Bellvitge Universitary Hospital

    Badalona, 08907

  • Hospital del Mar

    Barcelona, 08003

  • Hospital Clinic i Provincial

    Barcelona, 08036

  • Hospital de la Santa Creu i Sant Pau

    Barcelona, 08041

  • Hospital Univ. Virgen de la Arrixaca

    El Palmar, Murcia, 30120

  • Hospital Virgen de la Arrixaca

    El Palmar, Murcia, 30120

  • Hospital de Lleida "Arnau de Vilanova"

    Lleida, 25198

  • Hospital Universitario de la Princesa

    Madrid, 28006

  • Hospital Gregorio Marañón

    Madrid, 28009

  • Hospital Ramón y Cajal

    Madrid, 28034

  • Hospital Clínico San Carlos

    Madrid, 28040

  • Hospital Universitario La Paz

    Madrid, 28046

  • H. Clinico Univ. Virgen de la Victoria

    Málaga, Malaga, 29010

  • Hospital Universitario Marqués de Valdecilla

    Santander, 39008

  • Hospital Clinico de Santiago

    Santiago de Compostela, 15706

  • Hospital Universitario Virgen del Rocío

    Seville, 41013

  • Hospital Universitari Joan XXIII

    Tarragona, 43005

  • Hospital Clinico Universitario de Valencia

    Valencia, 46010

  • Hospital Clínico Universitario de Valladolid

    Valladolid, 47003

  • Hospital Alvaro Cunqueiro de Vigo

    Vigo, 36312

Other trials in Spain

Brazil22 sites

  • Jmf Clínica Do Coração Ltda

    Aracaju, 49055-530

  • NUPEC Cardio

    Belo Horizonte, Minas Gerais, 30220-140

  • Associação Lar São Francisco de Assis na Providência de Deus - Bragança Paulista

    Bragança Paulista, São Paulo, 12916-542

  • Hospital do Coração do Brasil - Rede Do'r

    Brasília, Federal District, 70390-700

  • Instituto de Pesquisa Clínica de Campinas

    Campinas, São Paulo, 13060-080

  • PUCCAMP - Hospital e Maternidade Celso Pierro

    Campinas, São Paulo, 13060-803

  • Integral Pesquisa e Ensino

    Cidade Nova Votuporanga, São Paulo, 15501-405

  • Hospital Ruy Azeredo Ltda

    Goiânia, Goiás, 74453200

  • Irmandade da Santa Casa de Misericórdia de Marília

    Marília, São Paulo, 17515-900

  • Hospital Israelita Albert Einstein

    Morumbi, São Paulo, 05651-901

  • Irmandade Santa Casa de Misericórdia de Passos

    Passos, Minas Gerais, 37904-020

  • Hospital Maternidade e Pronto Socorro Santa Lúcia

    Poços de Caldas, Minas Gerais, 37706-106

  • Irmandade da Santa Casa de Misericordia de Porto Alegre

    Porto Alegre, Rio Grande do Sul, 90050-170

  • Hospital São Lucas - PUC/RS

    Porto Alegre, Rio Grande do Sul, 90610-000

  • Hospital Mãe de Deus - Porto Alegre

    Porto Alegre/RS, 90840-440

  • ASSOCIAÇÃO LAR SÃO FRANCISCO DE ASSIS NA PROVIDÊNCIA DE DEUS - Hospital Regional de Presidente Prudente

    Presidente Prudente, São Paulo, 19050-680

  • Hospital Agamenon Magalhães

    Recife, Pernambuco, 52051-380

  • CIP Centro Integrado de Pesquisas do Hospital de Base

    São José do Rio Preto, São Paulo, 15090-000

  • Instituto Dante Pazzanese de Cardiologia

    São Paulo, São Paulo, 04012-909

  • Hospital das Clínicas da Universidade Federal do Triangulo Mineiro

    Uberaba, Minas Gerais, 38025-350

  • Centro de Pesquisa Clínica do Hospital de Clínicas da Universidade Federal de Uberlândia

    Uberlândia, Minas Gerais, 38405-325

  • Integral Pesquisa e Ensino

    Votuporanga, São Paulo, 15500-269

Other trials in Brazil

Mexico20 sites

  • Hospital Cardiológica Aguascalientes

    Aguascalientes, Aguascalientes, 20230

  • Hospital Juárez de Mexico

    Ciudad de México, D.F., 07760

  • Hospital General de México (HGM)

    Cuauhtémoc, México, D.F., 06720

  • Hospital Angeles de Culiacan

    Culiacán, Sinaloa, 80020

  • Hospital Civil de Guadalajara Fray Antonio Alcalde

    Guadalajara, Jalisco, 44280

  • Nuevo Hospital Civil "Dr. Juan I. Menchaca"

    Guadalajara, Jalisco, 44340

  • Hermosillo Heart Team

    Hermosillo, Sonora, 83280

  • Centro de Imagen y Tecnologia en Intervención Cardiovascular

    México, La Magdalena Contreras, 10700

  • Hospital Angeles de las Lomas

    México, State of Mexico, 52763

  • Centro Médico Nacional Siglo XXI

    Mexico City, 06720

  • Instituto Nacional de Cardiología Ignacio Chávez

    Mexico City, 14080

  • UMAE Hospital IMSS

    Monterrey, Nuevo León, 64360

  • Hospital Universitario Dr. José Eleuterio González

    Monterrey, Nuevo León, 64460

  • Centro de Estudios Clinicos de Querétaro S.C.

    Querétaro, 76000

  • Centro de Atención e Investigación Cardiovascular del Potosi (CICAP)

    San Luis Potosí City, 44340

  • Centro de Atención e Investigación Cardiovascular del Potosi

    San Luis Potosí City, 44340

  • Servicios Integrales Nova de Monterrey

    San Nicolás de los Garza, 66450

  • Instituto Nacional de Ciencias Médicas y Nutrición

    Tlalpan, Mexico City, 14080

  • Unidad Medica de Alta Especialidad No. 71 IMSS

    Torreón, Coahuila, 27000

  • Hospital Angeles de Xalapa

    Xalapa, Veracruz, 91193

Other trials in Mexico

Argentina19 sites

  • Sanatorio Finochietto

    Buenos Aires, 1187

  • Hospital Italiano

    Buenos Aires, C1181ACH

  • Cardiología Hospital J. M. Ramos Mejia

    Buenos Aires, C1221ADC

  • Instituto Cardiovascular Buenos Aires

    CABA, Buenos Aires, C1428ART

  • Fundacion Favaloro

    CABA, Buenos Aires, Argentina, C1093AAS

  • Sanatorio Güemes

    CABA, City of Buenos Aires, C1180AAX

  • Clínica Privada Velez Sarsfield

    Córdoba, 5000

  • Instituto de Cardiología de Corrientes

    Corrientes, W3400AMZ

  • Hospital Español de Mendoza

    Godoy Cruz, Mendoza, Mendoza Province, 5501

  • Hospital Italiano de la Plata

    La Plata, Buenos Aires, B 1900AXI

  • Hospital Universitario Austral - Instituto de Cardiologia

    Pilar, Buenos Aires, 1663

  • Hospital Universitario Austral

    Pilar, Buenos Aires, 1663

  • Sanatorio Modelo Quilmes

    Quilmes, Buenos Aires, 1878

  • Sanatorio Parque

    Rosario, Santa Fe Province, 2000

  • Hospital del Centenario

    Rosario, Santa Fe, Santa Fe Province, S2002KDT

  • Centro Privado de Cardiología

    San Miguel de Tucuimán, Tucumán Province, 4000

  • Centro de Investigación C.I.C.E 9 de Julio - Sanatorio 9 de Julio

    San Miguel de Tucumán, Tucumán Province, T4000DPX

  • Fundación Nuestra Señora del Rosario - Estudios Clínicos los Arroyos

    San Nicolás de los Arroyos, Buenos Aires, B2900ACF

  • Hospital Dr. Jose Maria Cullen

    Santa Fe, 3000

Other trials in Argentina

France19 sites

  • Centre Hospitalier Universitaire de Besancon-Hopital Jean Minjoz

    Besançon, 25030

  • Hospices Civils de Lyon- Hopital Louis Pradel

    Bron, 69500

  • Centre Hospitalier Universitaire de Caen Normandie- Cote de Nacre

    Caen, 14033

  • Centre Hospitalier Regional Universitaire de Tours-Hopital Trousseau

    Chambray-lès-Tours, 37170

  • Centre Hospitalier Sud Francilien

    Corbeil-Essonnes, 91100

  • Centre Hospitalier Universitaire Grenoble Alpes-Site Nord Michallon

    Grenoble, 38043

  • Les Hopitaux de Chartres-Hopital Louis Pasteur

    Le Coudray, 28630

  • Centre Hospitalier Universitaire de Lille-Institut Coeur Poumon

    Lille, 59000

  • Centre Hospitalier Saint Joseph Saint Luc

    Lyon, 69007

  • Assistance Publique Hopitaux de Marseille-Hopital de La Timone

    Marseille, 13005

  • Centre Hospitalier Universitaire de Nice-Hopital Pasteur

    Nice, 06000

  • Aphp-Hopital La Pitie Salpetriere

    Paris, 75013

  • Ap-Hp-Hopital Europeen Georges Pompidou

    Paris, 75015

  • Ap-Hp-Hopital Bichat-Claude Bernard

    Paris, 75877

  • Centre Hospitalier Universitaire de Bordeaux-Hopital Haut Leveque

    Pessac, 33600

  • Centre Hospitalier Universitaire de Poitiers

    Poitiers, 86000

  • Centre Hospitalier Universitaire de Toulouse-Hopital Rangueil-1

    Toulouse, 31059

  • Centre Hospitalier Universitaire de Toulouse-Hopital Rangueil

    Toulouse, 31059

  • Chru de Nancy - Hopital Brabois

    Vandœuvre-lès-Nancy, 54500

Other trials in France

Netherlands18 sites

  • Jeroen Bosch Zkh

    's-Hertogenbosch, 5223 GZ

  • Noordwest Ziekenhuisgroep

    Alkmaar, 1815 JD

  • Meander MC

    Amersfoort, 3813 TZ

  • OLVG

    Amsterdam, 1091 AC

  • Rijnstate Ziekenhuis

    Arnhem, 6815 AD

  • Amphia Ziekenhuis

    Breda, 4818 CK

  • Catharina Zkh Eindhoven

    Eindhoven, 5623 EJ

  • Medisch Spectrum Twente - Cardiologie

    Enschede, 7512 KZ

  • Groene Hart Zkh Gouda

    Gouda, 2803HH

  • UMC Groningen

    Groningen, 9713 GZ

  • Tergooi, Hilversum

    Hilversum, 1212 VG

  • RadboudUMC

    Nijmegen, 6525 GA

  • Canisius-Wilhelmina Ziekenhuis

    Nijmegen, 6532 SZ

  • Bravis Zkh Roosendaal

    Roosendaal, 4708 AE

  • Maasstad Ziekenhuis - Cardiologie

    Rotterdam, 3079 DZ

  • Ikazia Ziekenhuis

    Rotterdam, 3083 AN

  • HMC, locatie Westeinde

    The Hague, 2512 VA

  • ETZ TweeSteden - Cardiologie

    Tilburg, 5042 AD

Other trials in Netherlands

Malaysia16 sites

  • Hospital Sultanah Bahiyah

    Alor Star, Kedah, 05460

  • Hospital Canselor Tuanku Muhriz UKM

    Cheras, Kuala Lumpur, 56000

  • Hospital Pulau Pinang

    George Town, Pulau Pinang, 10990

  • Hospital Raja Permaisuri Bainun Ipoh

    Ipoh, Perak, 30450

  • Hospital Sultanah Aminah

    Johor Bahru, Johor, 80100

  • Hospital Serdang

    Kajang, Selangor, 43000

  • Hospital Raja Perempuan Zainab II

    Kota Bharu, Kelantan, 15586

  • Hospital Universiti Sains Malaysia_Kota Bharu, Kelantan

    Kota Bharu, Kelantan, 16150

  • Sarawak Heart Centre

    Kota Samarahan, Sarawak, 94300

  • National Heart Institute

    Kuala Lumpur, 50400

  • Hospital Universiti Kebangsaan Malaysia

    Kuala Lumpur, 56000

  • Hospital Tengku Ampuan Afzan

    Kuantan, Pahang, 25100

  • Sultan Ahmad Shah Medical Centre @IIUM

    Kuantan, Pahang, 25200

  • University Malaya Medical Centre

    Lembah Pantai, Kuala Lumpur, 59100

  • Hospital Queen Elizabeth II

    Sabak Bernam, 88300

  • Universiti Teknologi MARA, Sungai Buloh Campus

    Sungai Buloh, Selangor, 47000

Other trials in Malaysia

Czechia14 sites

  • Fakultni nemocnice Brno

    Brno, 625 00

  • FN u Sv. Anny

    Brno, 656 91

  • Nemocnice České Budějovice a.s.

    České Budějovice, 370 01

  • Krajská nemocice Liberec, a.s

    Liberec, Czech Republic, 460 01

  • Fakultní nemocnice Olomouc

    Olomouc, 779 00

  • Nemocnice Pardubickeho kraje a.s.

    Pardubice, 53203

  • Fakultni nemocnice Plzen - Lochotin

    Plzen - Lochotín, 323 00

  • Fakultní nemocnice Královské Vinohrady

    Prague, 100 00

  • II. interni klinika VFN - Kardiologie a angiologie

    Prague, 128 08

  • IKEM

    Prague, 140 21

  • Nemocnice na Homolce

    Prague, 150 30

  • Nemocnice AGEL Třinec-Podlesí a.s.

    Třinec, 739 61

  • Krajská zdravotní, a.s. - Masarykova nemocnice v Ústí nad Labem, o.z.

    Ústní Nad Labem, Czechia, 400 11

  • Krajská nemocnice T.Bati a.s.

    Zlín, 762 75

Other trials in Czechia

Israel11 sites

  • Shamir MC - Cardiology Department

    Beer Yaakov, 7033001

  • Hillel Yaffe MC - Cardiology Department

    Hadera, 3810101

  • Rambam MC - Cardiac Intensive Care Unit

    Haifa, 3109601

  • Wolfson MC - The Heart Institute

    Holon, 58100

  • Hadassah Ein Karam MC - Cardio Department

    Jerusalem, 91120

  • Hadassah Mount Scorpus MC - Cardiology department

    Jerusalem, 9765422

  • Meir MC - Cardiology department

    Kfar Saba, 4428164

  • Rabin MC -Beilinson - Cardiac intensive unit

    Petah Tikva, 4941492

  • Kaplan MC - Cardiac Intensive Care

    Rehovot, 7661041

  • Sourasky MC - Cardio Vascular Research Center

    Tel Aviv, 6423906

  • Sheba MC - Cardiology Clinical Research Unit

    Tel HaShomer, 5265601

Other trials in Israel

Denmark8 sites

  • Aalborg Universitetshospital Kardiologisk Afdeling

    Aalborg, 9000

  • Aarhus Universitetshospital, Hjertesygdomme

    Aarhus N, 8200

  • Aalborg Universitetshospital Hjertemedicinsk Afdeling

    Gistrup, 9260

  • Herlev og Gentofte Hospital

    Hellerup, Capital Region, 2900

  • Nordsjællands hospital - Kardiologisk Forskning

    Hillerød, 3400

  • Rigshospitalet - Kardiologisk Forskningsenhed

    København Ø, 2100

  • Odense Universitetshospital, Kardiologisk afd.

    Odense C, 5000

  • Svendborg Sygehus - Kardiologisk

    Svendborg, 5700

Other trials in Denmark

About this study

Official title: ARTEMIS - Effects of Ziltivekimab Versus Placebo on Cardiovascular Outcomes in Patients With Acute Myocardial Infarction

The research study is being done to see if ziltivekimab can be used to treat people who were admitted to hospital because of a heart attack. Ziltivekimab might reduce development of heart disease, thereby preventing new heart attacks or strokes. Participants will either get ziltivekimab (active medicine) or placebo (a dummy medicine which has no effect on the body). Which treatment participants get is decided by chance. The chance of getting ziltivekimab or placebo is the same. The participant will need to inject the study medicine into a flat skin surface in there stomach, thigh, or upper arm once every month. Ziltivekimab is not yet approved in any country or region in the world. It is a new medicine that doctors cannot prescribe. The study will last for about 2 years.

Being tested
Ziltivekimab, Placebo

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • ZiltivekimabDrug

    Ziltivekimab will be adminsitered subcutaneously as an initial loading dose of Dose 1 followed by a maintenance dose of Dose 2 once- monthly.

  • PlaceboDrug

    Placebo matched to ziltivekimab will be adminsitered subcutaneously as an initial loading dose followed by a maintenance dose once-monthly.

Study groups in NCT06118281
Study groupRoleWhat they receive
ZiltivekimabExperimentalParticipants will receive an initial loading dose of ziltivekimab Dose 1 subcutaneously (s.c.) as early as possible after invasive procedure, and latest within 36 hours of hospitalisation for ST-elevation myocardial infarction (STEMI) and within 48 hours of hospitalisation for non-ST-elevation myocardial infarction (NSTEMI), followed by ziltivekimab Dose 2 s.c. once-monthly during the treatment period (estimated up to 2 years) added to standard of care.
Receives: Drug: Ziltivekimab
Placebo ziltivekimabExperimentalParticipants will receive placebo matched to ziltivekimab at an initial loading dose subcutaneously (s.c.) as early as possible after invasive procedure, and latest within 36 hours of hospitalisation for STEMI and latest within 48 hours of hospitalisation for NSTEMI, followed by placebo matched to ziltivekimab s.c. once-monthly during the treatment period (estimated up to 2 years) added to standard of care.
Receives: Drug: Placebo

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Time to first occurrence of a 3-component major adverse cardiovascular event (MACE) endpoint comprising: Cardiovascular (CV) death, Non-fatal myocardial infarction (MI), Non-fatal stroke

    Measured in months.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

Secondary outcomes (28)

  1. Number of CV death, non-fatal MI, non-fatal stroke

    Measured as count of events.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  2. Time to first occurrence of a composite MACE endpoint consisting of: All-cause mortality, Non-fatal MI, Non-fatal stroke

    Measured in months.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  3. Number of all-cause mortality, non-fatal MI, non-fatal stroke

    Measured as count of events.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  4. Time to first occurrence of non-fatal MI

    Measured in months.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  5. Time to first occurrence of MI (fatal and non-fatal)

    Measured in months.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  6. Time to first occurrence of non-fatal stroke

    Measured in months.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  7. Time to first occurrence of stroke (fatal and non-fatal)

    Measured in months.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  8. Time to first occurrence of a 3-component coronary MACE endpoint comprising:CV death, Non-fatal MI, Ischaemia-driven coronary revascularisation

    Measured in months.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  9. Time to first occurrence of a 5-component expanded MACE endpoint comprising: CV death, Non-fatal MI, Non-fatal stroke, Ischaemia-driven coronary revascularisation, Heart failure (HF) hospitalisation or urgent HF visit

    Measured in months.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  10. Number of CV death, non-fatal MI, non-fatal stroke, ischaemia-driven coronary revascularisation, or HF hospitalisation or urgent HF visit

    Measired as count of events.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  11. Time to first occurrence of a 3-component HF endpoint comprising: CV death, HF hospitalisation or urgent HF visit, Outpatient HF visit

    Measured in months.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  12. Number of CV deaths, HF hospitalisation or urgent HF visits or outpatient HF visit

    Measured in count of events.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  13. Time to first occurrence of a 2-component HF endpoint comprising: CV death, HF hospitalisation or urgent HF visit

    Measured as months.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  14. Number of CV deaths, HF hospitalisation or urgent HF visits

    Measured in count of events.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  15. Time to first occurrence of a 2-component expanded HF endpoint comprising: HF hospitalisation or urgent HF visit, Outpatient HF visit

    Measured as months.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  16. Number of HF hospitalisation or urgent HF visit or outpatient HF visit

    Measured as count of events.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  17. Number of outpatient HF visit

    Measured in count of events.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  18. Time to occurrence of CV death

    Measured as months.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  19. Time to occurrence of all-cause death

    Measured as months.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  20. Time to first occurrence of 6-component vascular event endpoint: CV death, Non-fatal MI, Non-fatal stroke, Ischaemia-driven coronary revascularisation, Non-coronary revascularisation procedure, Any other non-coronary ischaemic event excluding stroke

    Measured in months.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  21. Number of CV death, non-fatal MI and non-fatal stroke, ischaemia-driven coronary revascularisation, non-coronary revascularisation procedure, or any other non-coronary ischaemic event excluding stroke

    Measured as count of events.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  22. Number of ischaemia-driven coronary revascularisation

    Measured as count of events.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  23. Time to first occurrence of ischaemia-driven coronary revascularisation or any non-coronary revascularisation

    Measured in months.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  24. Number of ischaemia-driven coronary revascularisation or any non-coronary revascularisation

    Measured as count of events.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  25. Number of cardiovascular hospitalisations

    Measured as count of events.

    Measured: From randomisation (month 0) to 1 month/ 30 days

  26. Number of cardiovascular hospitalisations

    Measured as count of events.

    Measured: From randomisation (month 0) to 12 months

  27. Number of hospitalisations with infection as primary cause or death due to infection

    Measured as count of events.

    Measured: From randomisation (month 0) to end-of-study (up to 25 months)

  28. Change in high-sensitivity C-reactive protein (hs-CRP)

    Measured as ratio to baseline.

    Measured: From randomisation (month 0) to 6 months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted7 Nov 2023
  2. Study start25 Jun 2024
  3. Primary completion29 Jan 2027 (estimated)
  4. Study completion29 Jan 2027 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase 3
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
Quadruple blind
Who is masked
Participant, Care provider, Investigator, Outcomes assessor
Enrolment
10,000 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06118281
Sponsor's protocol ID
EX6018-4979
Other IDs
U1111-1294-3473, 2023-506876-28, 2023
Acronym
ARTEMIS
Status last verified
Sep 2026
First submitted
31 Oct 2023
Last updated
9 Sep 2026
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
Yes
FDA-regulated device
No
Individual data sharing
Yes: According to the Novo Nordisk disclosure commitment on novonordisk-trials.com

Questions about this trial

What is this clinical trial studying?

A Phase 3 study testing Ziltivekimab in people with Cardiovascular Risk and Acute Myocardial Infarction (AMI), run by Novo Nordisk A/S at 836 sites in 24 countries.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 8 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: under way, not looking for participants, as of the sponsor's last update on 9 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 836 sites in United States, India, Poland, China, Italy and 19 more countries. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

What does this phase mean?

Phase 3 studies compare the treatment with the current standard treatment or a placebo in a large group, to confirm how well it works and watch for side effects.

Not every study follows the same path, and some studies (observational studies, device studies) have no phase.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Time to first occurrence of a 3-component major adverse cardiovascular event (MACE) endpoint comprising: Cardiovascular (CV) death, Non-fatal myocardial infarction (MI), Non-fatal stroke (time frame: From randomisation (month 0) to end-of-study (up to 25 months)). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT06118281.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Sep 2026.

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