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Heart FailureAMERICCAASSNCT05295641

American Registry of Ambulatory or Acutely Decompensated Heart Failure

An observational study of Heart Failure and Acute Heart Failure (AHF), run by Fundacion Clinica Valle del Lili at 119 sites in 21 countries.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
Search all trials

Trial summary

The purpose of this study is to better characterize and understand the population of patients with ambulatory or acutely decompensated heart failure in the American continent, getting to know their sociodemographic, clinical and paraclinical characteristics Read more about this study

Who is it for?
Ages 18 years and older
How many people
6,732 participants
Where
119 sitesin 21 countries
Study dates
1 Apr 2022to 31 Jan 2025
How long will I take part?
12 Months
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Study population: Heart failure patients with either ambulatory diagnosis or an acute decompensation

Who may be able to join

  • Patient aged 18 years or older and one of the following:
  • Hospitalized patient with admission diagnosis of acutely decompensated heart failure or
  • Outpatient with confirmed diagnosis (main or complementary) of heart failure

Who cannot join

  • Hospitalized patient with principal diagnosis of another cardiovascular / non-cardiovascular pathology and who develops an acute decompensation of heart failure during hospitalization.
  • Patient on heart transplant waiting list
  • Patient who has implanted or is in process of implanting a long-term ventricular assist device (eg, Heart Mate II, Heart Mate III) as a target therapy or bridge therapy to other therapies
  • Patient in whom palliative management has been previously defined for his/her cardiac condition (i.e. Heart failure) or for another associated medical condition (cancer, chronic obstructive pulmonary disease (COPD), etc.)
  • Patient who is discharged or referred to another institution within 48 hours of hospital stay
  • Inability to comply with programmed follow-ups (telephone or in person) due to social, personal or other conditions considered by the principal investigator
  • Life expectancy less than 6 months given a condition other than heart failure (Cancer, COPD, etc.)

Trial locations and contacts

119 sites in 21 countries.

119 sites in 21 countries

Colombia17 sites

  • Sociedad Clínica Iberoamericana

    Barranquilla, Atlántico, 08000

  • Clínica General del Norte

    Barranquilla

  • Clínica del Occidente

    Bogotá, Cundinamarca, 110851

  • Fundación Cardioinfantil

    Bogotá, Cundinamarca, 110911

  • Fundación Santa Fé de Bogotá

    Bogotá, Cundinamarca, 110911

  • Hospital Santa Clara

    Bogotá

  • Fundación Valle del Lili

    Cali, Valle del Cauca Department, 760032

  • Clínica Medilaser Florencia

    Florencia, Departamento del Caquetá, 180001-180009

  • Fundación Cardiovascular de Colombia

    Floridablanca, Santander Department

  • Clinica Avidanti S.A.S

    Ibague, Tolima Department, 730001

  • Instituto Todo Por El Corazón

    Manizales, Caldas Department, 170002

  • Clinica Cardio VID

    Medellín, Antioquia, 050001

  • Hospicardio

    Montería, Departamento de Córdoba

  • Unimedic Ips

    Pasto, Departamento de Nariño

  • Clínica los Rosales S.A. - Centro Médico para el Corazón

    Pereira, Risaralda Department, 660003

  • Instituto Grupsalud

    Santa Marta, Magdalena Department, 470001

  • Sociedad Cardiológica Colombiana S.A.S.

    Villavicencio

Other trials in Colombia

Cuba17 sites

  • Hospital Provincial Clínico Quirúrgico Docente Carlos Manuel De Céspedes

    Bayamo

  • Hospital Provincial Clínico Quirúrgico Docente Manuel Ascunce Domenech

    Camagüey

  • Hospital Provincial Dr. Antonio Luaces Iraola

    Ciego de Ávila

  • Hospital General Orlando Pantoja Tamayo

    Contramaestre

  • Instituto de Cardiología y Cirugía Cardiovascular

    La Habana, Departamento Occidental, 10000-19999

  • Hospital Clínico Quirúrgico Docente Calixto García Íñiguez

    La Habana

  • Hospital Clínico Quirúrgico Docente Dr. Enrique Cabrera

    La Habana

  • Hospital Provincial Camilo Cienfuegos

    La Habana

  • Hospital General Docente Dr. Ernesto Guevara De La Serna

    Las Tunas

  • Hospital Provincial Clínico Quirúrgico Docente Cmte. Faustino Pérez

    Matanzas

  • Hospital Clínico Quirúrgico Docente Héroes Del Baire

    Nueva Gerona

  • Hospital Provincial Docente Marting Chang Puga

    Nuevitas

  • Hospital Provincial Clinico Quirurgico Docente Leon Cuervo Rubio

    Pinar del Río, Provincia de Pinar del Río, 20100

  • Hospital Provincial Clínico Quirúrgico Docente Abel Santamaría

    Pinar del Río

  • Hospital Clinico Quirurgico Docente Ivan Portuondo

    San Antonio de los Baños, Artemisa, 32700

  • Cardiocentro Santiago de Cuba

    Santiago de Cuba

  • Hospital Provincial Saturnino Lora

    Santiago de Cuba

Other trials in Cuba

Argentina16 sites

  • Sanatorio Santa Clara Talar

    Buenos Aires, 1617

  • Hospital General de Agudos Carlos G. Durand

    Buenos Aires

  • Hospital Italiano de Córdoba

    Córdoba, Córdoba Province

  • Hospital Privado Universitario de Córdoba

    Córdoba, 5000

  • Instituto Modelo de Cardiología Privado SRL

    Córdoba

  • Instituto de Cardiología Juana Francisca Cabral Bolívar

    Corrientes, 3400

  • Clinica Vrsalovic / Clinica del Angelo

    Formosa, Formosa Province, 3600

  • Sanatorio Modelo Quilmes

    Quilmes, Buenos Aires, 1878

  • Sanatorio de la Trinidad Quilmes y Centro Gallego

    Quilmes, Buenos Aires

  • Instituto Cardiovascular del Rosario

    Rosario, Santa Fe Province, 2000

  • Hospital San Bernardo

    Salta, Salta Province, 4400

  • Clínica El Castaño - CIMAC

    San Juan, San Juan Province, 5400

  • Hospital Descentralizado Dr. Guillermo Rawson

    San Juan

  • Hospital Público Dr. Marcial V. Quiroga

    San Juan

  • Clínica CERHU / Hospital Central Ramón Carrillo

    San Luis, San Luis Province

  • Establecimiento Asistencial Gobernador Centeno

    Santa Rosa, La Pampa Province, 6300

Other trials in Argentina

Ecuador10 sites

  • Hospital José Carrasco Arteaga / Instituto ecuatoriano de seguridad social

    Cuenca

  • Hospital Luis Vernaza

    Guayaquil, Guayas, 090101 - 090158

  • Hospital Clínica Kennedy

    Guayaquil, Guayas, 090512

  • Clinica Jesús De Nazareth / Hospital San Marcos

    Machala

  • Centro Médico de Especialidades Ameds

    Manta, Manabí, EC130850

  • HOSPICOR

    Manta, Manabí, EC130850

  • Centro Cardiológico A.C.I

    Portoviejo, Manabí, EC130150

  • Hospital General EISS Portoviejo

    Portoviejo

  • Hospital Metropolitano

    Quito, Pichincha, 170521

  • Centro De Diagnóstico Y Tratamiento De Enfermedades (Cdt) Cardiovasculares Cardioheredia

    Samborondón

Other trials in Ecuador

Venezuela10 sites

  • Cardiología Tropical Azoátegui

    Anzoátegui

  • ASCARDIO

    Barquisimeto, Lara, 3001

  • Centro Clinico Santa Rosa

    Cumaná, Sucre, 6101

  • Atimed C.A

    Cumaná

  • Instituto Autónomo Hospital Universitario de Los Andes

    Mérida, Mérida, 5101

  • Unidad Cardiovascular Ferrer

    Puerto Cabello, Carabobo

  • Clínica Chilemex

    Puerto Ordaz and San Felix, Bolívar, 8050

  • IVSS Hospital Dr. Rafael Calles Sierra

    Punto Fijo

  • Centro Policlínico Valencia

    Valencia, Carabobo, 2001

  • Unicor/Funvic

    Valencia

Other trials in Venezuela

Paraguay8 sites

  • Hospital Central - Instituto de Previsión Social

    Asunción, 1001-1925

  • Instituto Nacional de Cardiología "Prof. Dr. Juan A. Catonni"

    Asunción, 1001-1925

  • Instituto Cardiovascular del Sanatorio Migone

    Asunción

  • Sanatorio Adventista de Asunción

    Asunción

  • Sanatorio Italiano

    Asunción

  • Clinicor Estudios Cardiológicos

    Concepción

  • Hospital Nacional de Itaugua

    Itauguá, Central Department, 2740

  • Hospital de Clínicas - Facultad de ciencias médicas

    San Lorenzo

Other trials in Paraguay

Mexico7 sites

  • Centenario Hospital Miguel Hidalgo

    Aguascalientes, Aguascalientes, 20000 - 20999

  • Hospital Español. Sociedad de Beneficencia Española I.A.P

    Mexico City, 01000-16999

  • Instituto Nacional de Cardiología Ignacio Chávez

    Mexico City, 14080

  • Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran

    Mexico City, 14080

  • Servicios Profesionales Del Sagrado Corazón De Jesús S.C.

    Mexico City

  • Christus Muguerza Hospital Alta Especialidad

    Monterrey, Nuevo León, 64000

  • TecSalud, Escuela de Medicina y Ciencias de la Salud del ITESM

    Monterrey

Other trials in Mexico

Peru6 sites

  • Luis Heysen Inchaustegui - ESSALUD

    Chiclayo

  • Hospital III EsSalud Chimbote

    Chimbote, Ancash

  • Hospital María Auxiliadora

    Lima, 15056

  • Hospital Nacional Arzobispo Loayza

    Lima

  • Hospital Nacional Daniel Alcides Carrión

    Lima

  • Instituto Cardiovascular Clinicor Norte

    Lima

Other trials in Peru

Guatemala5 sites

  • Cardiocentro Chimaltenango

    Chimaltenango, 04001

  • Hospital General San Juan de Dios

    Guatemala City, Departamento de Guatemala, 1001 - 1073

  • Hospital Roosevelt

    Guatemala City, Departamento de Guatemala, 1001 - 1073

  • Clínicas HART y Hospital Regional de Occidente

    Quetzaltenango, Departamento de Quetzaltenango, 09001

  • Hospital Regional de Zacapa

    Zacapa, 19001

Other trials in Guatemala

Dominican Republic4 sites

  • Centro Médico Siglo 21

    San Francisco de Macorís

  • Clínica Universitaria Unión Médica del Norte

    Santiago de los Caballeros, Santiago Province, 51000

  • Hospital Regional Presidente Estrella Ureña

    Santiago de los Caballeros, Santiago Province, 51000

  • Hospital Metropolitano de Santiago Homs

    Santiago de los Caballeros

Other trials in Dominican Republic

Costa Rica3 sites

  • Hospital San Vicente de Paúl

    Heredia, 40103

  • Hospital Clínica Bíblica

    San José, 10102

  • Hospital México, CCSS

    San José, 10102

Other trials in Costa Rica

El Salvador3 sites

  • Clínica de Cardiología y Ortopedia CCO

    San Salvador, San Salvador Department

  • Instituto Salvadoreño del Seguro Social

    San Salvador, San Salvador Department

  • Clínica del Corazón Sinusal

    San Salvador

Other trials in El Salvador

United States2 sites

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390

  • North Shore University Hospital, Nothwell Health

    Manhasset, New York, 11030

Other trials in United States

Bolivia2 sites

  • Hospital Universitario Japonés

    Santa Cruz de la Sierra, Santa Cruz Department

  • Caja Petrolera de Salud

    Santa Cruz de la Sierra

Other trials in Bolivia

Honduras2 sites

  • Cardio Medical Center

    Tegucigalpa, Francisco Morazán Department, 11101

  • Instituto Nacional Cardiopulmonar

    Tegucigalpa, Francisco Morazán Department, 11101

Other trials in Honduras

Uruguay2 sites

  • Hospital de Clínicas Doctor Manuel Quintela

    Montevideo, 11000

  • Médica Uruguaya

    Montevideo

Other trials in Uruguay

Chile1 site

  • Instituto Nacional del Tórax

    Santiago

Other trials in Chile

Jamaica1 site

  • Heart institute of the caribbean

    Kingston

Other trials in Jamaica

Nicaragua1 site

  • Hospital Carlos R Huembes/Clinica Plaza España/Clinica Centro Medico Juigalpa

    Managua

Panama1 site

  • Hospital Santo Tomás

    Panama City

Other trials in Panama

Suriname1 site

  • Thorax Centrum Paramaribo /Academic Hospital Paramaribo

    Paramaribo

About this study

The purpose of this study is to better characterize and understand the population of patients with ambulatory or acutely decompensated heart failure in the American continent, getting to know their sociodemographic, clinical and paraclinical characteristics

Read the detailed description

An observational, prospective and multicenter study in which ambulatory patients with a confirmed diagnosis of heart failure and those admitted to the hospitalization service due to an episode of acutely decompensated heart failure will be invited to participate in order to better characterize this population

Participants who meet the eligibility criteria will be evaluated at the moment of recruitment. Follow-ups will be performed at 1, 6 and 12 months after the initial registry for hospitalized patients. For ambulatory patients follow-up will only be performed at 12 months. These initial evaluations and subsequents follow-ups will be carried out using a standardized form for the collection of hospital and outpatient data through an electronic platform

The purpose of this study is to know sociodemographic, clinical (clinical presentation, hemodynamic profiles, in-hospital and outpatient management, re-hospitalization rate, proportion of mortality, cumulative survival and heart failure readmission-free survival) and paraclinical characteristics of this population

Keywords
Decompensated, Outpatient, Treatment, Hospitalization, Mortality, Heart Failure, Americas, Registry, Inpatient
Medical subject headings
Heart Failure

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Characteristics of population with diagnosis of heart failure in America

    Sociodemographic characteristics of patients with heart failure

    Measured: Baseline

  2. Characteristics of population with diagnosis of heart failure in America

    Clinical and paraclinical characteristics of patients with heart failure

    Measured: Baseline, at Month 1, Month 6 and Month 12

Secondary outcomes (16)

  1. Outpatient management of heart failure

    Describe the ambulatory/outpatient management of patients with heart failure

    Measured: Baseline and at Month 12

  2. Relation between outpatient treatment of heart failure with proportion of hospitalization and mortality

    Relate outpatient pharmacological treatment with the proportion of hospitalization and mortality

    Measured: Baseline and at Month 12

  3. Clinical and hemodynamic presentation of acutely decompensated heart failure

    Describe the clinical and hemodynamic presentation of patients with acute decompensated heart failure

    Measured: Baseline

  4. In-hospital management of acutely decompensated heart failure

    Describe the in-hospital management of patients with acutely decompensated heart failure

    Measured: Baseline

  5. Proportion of in-hospital mortality related with acute decompensation of heart failure

    Determine the proportion of in-hospital mortality related with acute decompensation of heart failure

    Measured: Baseline

  6. Proportion of rehospitalization at 1, 6, 12 months after hospital discharge

    Determine the proportion of rehospitalization at 1, 6 and 12 months after hospital discharge

    Measured: Month 1, Month 6 and Month 12

  7. Proportion of mortality at 1, 6, 12 months after hospital discharge

    Determine the proportion of mortality at 1, 6 and 12 months after hospital discharge

    Measured: Month 1, Month 6 and Month 12

  8. Relation between hemodynamic profile of decompensation with proportion of mortality at 1, 6, 12 months after hospital discharge

    Relate the hemodynamic profile of decompensation with the proportion of in-hospital and ambulatory mortality at 1, 6 and 12 months after hospital discharge.

    Measured: Baseline, Month 1, Month 6 and Month 12

  9. Relation between in-hospital pharmacological treatment with mortality at 1, 6, 12 months after hospital discharge

    Relate hospital pharmacological treatment with inpatient and outpatient mortality at 1, 6 and 12 months after hospital discharge.

    Measured: Month 1, Month 6 and Month 12

  10. Relation between in-hospital pharmacological treatment with proportion of readmissions at 1, 6, 12 months after hospital discharge

    Relate hospital pharmacological treatment with the proportion of readmissions at 1, 6 and 12 months after hospital discharge.

    Measured: Month 1, Month 6 and Month 12

  11. Relation between outpatient pharmacological treatment with proportion of hospitalization and mortality at 1, 6, 12 months after hospital discharge

    Relate outpatient pharmacological treatment with the proportion of hospitalization and mortality at 1, 6 and 12 months after hospital discharge.

    Measured: Month 1, Month 6 and Month 12

  12. Differences among heart failure treatment considering sociodemographic characteristics

    Describe the differences among inpatient and outpatient treatment taking into account different demographic characteristics such as: gender, age, comorbidities, among others

    Measured: Baseline

  13. Differences among proportion of rehospitalization and heart failure mortality considering sociodemographic characteristics

    Describe the differences in the proportion of rehospitalization, hospital and outpatient mortality, taking into account different demographic characteristics: gender, age, comorbidities, among others

    Measured: Baseline

  14. Differences among proportion of rehospitalization and heart failure mortality considering implementation of optimal medical treatment

    Describe the differences in the proportion of rehospitalization, hospital and outpatient mortality, taking into account the implementation of optimal or recommended medical treatment in national and international guidelines

    Measured: Baseline, Month 1, Month 6 and Month 12

  15. Differences among hospitalization and heart failure mortality considering the use of cardiac devices

    Describe the differences between hospitalization and outpatient mortality taking into account the use of cardiac devices (cardiac resynchronization and/or implantable cardiac defibrillator) recommended in international guidelines

    Measured: Baseline, Month 1, Month 6 and Month 12

  16. Cumulative heart failure survival and readmission-free survival

    Evaluate cumulative survival and heart failure readmission-free survival

    Measured: Baseline, Month 1, Month 6 and Month 12

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted25 Mar 2022
  2. Study start1 Apr 2022
  3. Primary completion31 Jan 2025
  4. Study completion31 Jan 2025

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Prospective
Enrolment
6,732 participants (actual)
Target duration
12 Months
IDs, dates and publications
ClinicalTrials.gov ID
NCT05295641
Sponsor's protocol ID
FVL-1310
Acronym
AMERICCAASS
Status last verified
Apr 2025
First submitted
15 Mar 2022
Last updated
13 Apr 2025
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No: We do not plan to share IPD, since we are not allowed to share information concerning medical history of our patients

Publications

  • Adams KF Jr, Fonarow GC, Emerman CL, LeJemtel TH, Costanzo MR, Abraham WT, Berkowitz RL, Galvao M, Horton DP; ADHERE Scientific Advisory Committee and Investigators. Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE). Am Heart J. 2005 Feb;149(2):209-16. doi: 10.1016/j.ahj.2004.08.005.

    PubMed 15846257

  • Jonsson A, Edner M, Alehagen U, Dahlstrom U. Heart failure registry: a valuable tool for improving the management of patients with heart failure. Eur J Heart Fail. 2010 Jan;12(1):25-31. doi: 10.1093/eurjhf/hfp175.

    PubMed 20023041

  • McMurray JJ, Stewart S. Epidemiology, aetiology, and prognosis of heart failure. Heart. 2000 May;83(5):596-602. doi: 10.1136/heart.83.5.596. No abstract available.

    PubMed 10768918

  • Mosterd A, Hoes AW. Clinical epidemiology of heart failure. Heart. 2007 Sep;93(9):1137-46. doi: 10.1136/hrt.2003.025270.

    PubMed 17699180

  • Hernandez-Leiva E. [Epidemiology of acute coronary syndrome and heart failure in Latin America]. Rev Esp Cardiol. 2011 Jul;64 Suppl 2:34-43. doi: 10.1016/j.recesp.2011.01.022. Spanish.

    PubMed 21807285

  • Bocchi EA, Arias A, Verdejo H, Diez M, Gomez E, Castro P; Interamerican Society of Cardiology. The reality of heart failure in Latin America. J Am Coll Cardiol. 2013 Sep 10;62(11):949-58. doi: 10.1016/j.jacc.2013.06.013. Epub 2013 Jul 10.

    PubMed 23850910

  • Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JGF, Coats AJS, Falk V, Gonzalez-Juanatey JR, Harjola VP, Jankowska EA, Jessup M, Linde C, Nihoyannopoulos P, Parissis JT, Pieske B, Riley JP, Rosano GMC, Ruilope LM, Ruschitzka F, Rutten FH, van der Meer P. 2016 ESC Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure. Rev Esp Cardiol (Engl Ed). 2016 Dec;69(12):1167. doi: 10.1016/j.rec.2016.11.005. No abstract available. English, Spanish.

    PubMed 27894487

  • O'Gara PT, Kushner FG, Ascheim DD, Casey DE Jr, Chung MK, de Lemos JA, Ettinger SM, Fang JC, Fesmire FM, Franklin BA, Granger CB, Krumholz HM, Linderbaum JA, Morrow DA, Newby LK, Ornato JP, Ou N, Radford MJ, Tamis-Holland JE, Tommaso CL, Tracy CM, Woo YJ, Zhao DX. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2013 Jan 29;61(4):e78-e140. doi: 10.1016/j.jacc.2012.11.019. Epub 2012 Dec 17. No abstract available.

    PubMed 23256914

  • Brouwers FP, de Boer RA, van der Harst P, Voors AA, Gansevoort RT, Bakker SJ, Hillege HL, van Veldhuisen DJ, van Gilst WH. Incidence and epidemiology of new onset heart failure with preserved vs. reduced ejection fraction in a community-based cohort: 11-year follow-up of PREVEND. Eur Heart J. 2013 May;34(19):1424-31. doi: 10.1093/eurheartj/eht066. Epub 2013 Mar 6.

    PubMed 23470495

  • Lam CS, Donal E, Kraigher-Krainer E, Vasan RS. Epidemiology and clinical course of heart failure with preserved ejection fraction. Eur J Heart Fail. 2011 Jan;13(1):18-28. doi: 10.1093/eurjhf/hfq121. Epub 2010 Aug 3.

    PubMed 20685685

  • Levy D, Kenchaiah S, Larson MG, Benjamin EJ, Kupka MJ, Ho KK, Murabito JM, Vasan RS. Long-term trends in the incidence of and survival with heart failure. N Engl J Med. 2002 Oct 31;347(18):1397-402. doi: 10.1056/NEJMoa020265.

    PubMed 12409541

  • Roger VL, Weston SA, Redfield MM, Hellermann-Homan JP, Killian J, Yawn BP, Jacobsen SJ. Trends in heart failure incidence and survival in a community-based population. JAMA. 2004 Jul 21;292(3):344-50. doi: 10.1001/jama.292.3.344.

    PubMed 15265849

  • Barker WH, Mullooly JP, Getchell W. Changing incidence and survival for heart failure in a well-defined older population, 1970-1974 and 1990-1994. Circulation. 2006 Feb 14;113(6):799-805. doi: 10.1161/CIRCULATIONAHA.104.492033. Epub 2006 Feb 6.

    PubMed 16461823

  • Jhund PS, Macintyre K, Simpson CR, Lewsey JD, Stewart S, Redpath A, Chalmers JW, Capewell S, McMurray JJ. Long-term trends in first hospitalization for heart failure and subsequent survival between 1986 and 2003: a population study of 5.1 million people. Circulation. 2009 Feb 3;119(4):515-23. doi: 10.1161/CIRCULATIONAHA.108.812172. Epub 2009 Jan 19.

    PubMed 19153268

  • Levy D, Larson MG, Vasan RS, Kannel WB, Ho KK. The progression from hypertension to congestive heart failure. JAMA. 1996 May 22-29;275(20):1557-62.

    PubMed 8622246

Questions about this trial

What is this clinical trial studying?

An observational study of Heart Failure and Acute Heart Failure (AHF), run by Fundacion Clinica Valle del Lili at 119 sites in 21 countries.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 3 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 13 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 119 sites in Colombia, Cuba, Argentina, Ecuador, Venezuela and 16 more countries. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Characteristics of population with diagnosis of heart failure in America (time frame: Baseline). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT05295641, which also lists 25 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Apr 2025.

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AMERICCAASS Clinical Trial NCT05295641 | AzTrials