Anterior Cruciate Ligament InjuriesNCT04961736
Ultrasound Evaluation of Hamstring Tendon Regeneration After ACL Reconstruction and Its Influence
An observational study of Anterior Cruciate Ligament Injuries, run by Peking University Third Hospital at 1 site in China.
Trial summary
High incidence rate of knee osteoarthritis and gait analysis are important for early assessment of biomechanics. ACL injury is an ideal clinical model for studying knee osteoarthritis. Read more about this study
- Who is it for?
- Ages 18 to 35 yearsHealthy volunteers can take part
- Conditions the study is for
- Anterior Cruciate Ligament Injuries
- How many people
- 110 participants
- Where
- 1 siteChina
- Study dates
- 2 Feb 2018to 31 Dec 2022
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: Inclusion criteria: Age: 18-35 years old. Patients who have isolated ACL injury and receive ACL reconstruction surgery at Peking University Third Hospital. With isolated ACL injury (an ACL injury with no need for surgical repairs to other knee structures). All participants have no known disorders or diseases other than ACL rupture. Exclusion criteria: Female patients who are pregnant, or suspected pregnant, or in breastfeeding will be excluded from this study.
Who may be able to join
- 18-35 years old
- Patients who have isolated ACL injury and receive ACL reconstruction surgery at Peking University Third Hospital.
- With isolated ACL injury (an ACL injury with no need for surgical repairs to other knee structures).
- All participants have no known disorders or diseases other than ACL rupture.
Who cannot join
- Female patients who are pregnant, or suspected pregnant, or in breastfeeding will be excluded from this study.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Ultrasound Evaluation of Hamstring Tendon Regeneration After Anterior Cruciate Ligament Reconstruction and Its Influence on Gait Touch Information
High incidence rate of knee osteoarthritis and gait analysis are important for early assessment of biomechanics. ACL injury is an ideal clinical model for studying knee osteoarthritis.
To clarify the mechanism between the biomechanical status of knee joint and the change of gait touch information, and to provide scientific basis for quantifying and evaluating the biomechanical status of knee joint in dynamic load-bearing state.
Read the detailed description
Objective: to analyze the shape and function of the regenerated hamstring tendon within 2 years after the removal of the hamstring tendon in ACL reconstruction, reveal the change rule of the characteristics of hamstring tendon regeneration and its biomechanical changes, and guide the selection of operation and postoperative rehabilitation.
Methods: 55 healthy people and 55 male patients with ACL reconstruction were recruited. All completed the basic rehabilitation training under the guidance of the postoperative rehabilitation program. Using infrared motion capture system, three-dimensional force measuring platform, isokinetic muscle force testing system and ultrasound, the anterior cruciate ligament reconstruction patients were tested before operation, 2 weeks, 3 months, 6 months, 12 months after operation and 24 months after operation.
Outcome evaluation indicators and statistical methods: evaluation indicators: (1) three dimensional motion capture and analysis results: 1) peak ground reaction force; 2) three-dimensional angle and torque of hip, knee and ankle joints in different stages; (2) isokinetic muscle strength results: bilateral knee extension torque and knee flexion torque at different angles and angular velocities. (3)Ultrasound evaluation: the thickness, cross-sectional area and shear wave velocity of the semitendinosus were measured.
Statistical methods: ① repeated measurement analysis of variance (ANOVA) was used to test the effects of different time after operation on the three-dimensional gait characteristics, muscle strength and tendon regeneration characteristics. ② Independent sample t-test was used to test the three-dimensional characteristics, muscle strength and tendon condition of patients at different time points after operation. ③ The difference of three-dimensional gait characteristics, muscle strength and tendon between the healthy side and the affected side at different time points after operation were examined by paired sample t-test. ④ Bivariate correlation analysis was used to analyze whether the thickness, cross-sectional area, shear wave propagation velocity and postoperative time were related.
- Conditions
- Anterior Cruciate Ligament Injuries
- Being tested
- no intervention
- Keywords
- anterior cruciate ligament, gait analysis, plantar pressure, Ultrasound evaluation
- Medical subject headings
- Anterior Cruciate Ligament Injuries
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
no interventionOther
This is an observation study, with no intervention
| Study group | Role | What they receive |
|---|---|---|
| Anterior Cruciate Ligament injury and reconstruction group | According to the previous clinical diagnosis, volunteers who has never suffered the Anterior Cruciate Ligament injury. Receives: Other: no intervention | |
| normal control group | According to the previous clinical diagnosis, volunteers who has never suffered the lower extremity sports injuries. Receives: Other: no intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
peak ground reaction force
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: On the day of enrollment.
peak ground reaction force
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 3 months after Anterior Cruciate Ligament reconstruction.
peak ground reaction force
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 6 months after Anterior Cruciate Ligament reconstruction.
peak ground reaction force
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 12 months after Anterior Cruciate Ligament reconstruction.
peak ground reaction force
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 24 months after Anterior Cruciate Ligament reconstruction.
angle of hip in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 24 months after Anterior Cruciate Ligament reconstruction.
angle of hip in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: On the day of enrollment.
angle of hip in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 3 months after Anterior Cruciate Ligament reconstruction.
angle of hip in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 6 months after Anterior Cruciate Ligament reconstruction.
angle of hip in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 12 months after Anterior Cruciate Ligament reconstruction.
bilateral knee extension torque
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: On the day of enrollment.
bilateral knee extension torque
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 3 months after Anterior Cruciate Ligament reconstruction.
bilateral knee extension torque
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 6 months after Anterior Cruciate Ligament reconstruction.
bilateral knee extension torque
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 12 months after Anterior Cruciate Ligament reconstruction.
bilateral knee extension torque
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 24 months after Anterior Cruciate Ligament reconstruction.
knee flexion torque at different angles
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: On the day of enrollment.
knee flexion torque at different angles
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 3 months after Anterior Cruciate Ligament reconstruction.
knee flexion torque at different angles
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 6 months after Anterior Cruciate Ligament reconstruction.
knee flexion torque at different angles
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 12 months after Anterior Cruciate Ligament reconstruction.
knee flexion torque at different angles
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 24 months after Anterior Cruciate Ligament reconstruction.
angular velocities
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: On the day of enrollment.
angular velocities
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 3 months after Anterior Cruciate Ligament reconstruction.
angular velocities
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 6 months after Anterior Cruciate Ligament reconstruction.
angular velocities
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 12 months after Anterior Cruciate Ligament reconstruction.
angular velocities
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 24 months after Anterior Cruciate Ligament reconstruction.
the thickness of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: On the day of enrollment.
the cross-sectional area of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: On the day of enrollment.
the thickness of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: At 2 weeks after Anterior Cruciate Ligament reconstruction.
the cross-sectional area of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: At 2 weeks after Anterior Cruciate Ligament reconstruction.
the thickness of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: At 3 months after Anterior Cruciate Ligament reconstruction.
the cross-sectional area of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: At 3 months after Anterior Cruciate Ligament reconstruction.
the thickness of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: At 6 months after Anterior Cruciate Ligament reconstruction.
the cross-sectional area of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: At 6 months after Anterior Cruciate Ligament reconstruction.
the thickness of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: At 12 months after Anterior Cruciate Ligament reconstruction.
the cross-sectional area of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: At 12 months after Anterior Cruciate Ligament reconstruction.
the thickness of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: At 24 months after Anterior Cruciate Ligament reconstruction.
the cross-sectional area of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: At 24 months after Anterior Cruciate Ligament reconstruction.
shear wave velocity of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: On the day of enrollment.
shear wave velocity of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: At 3 months after Anterior Cruciate Ligament reconstruction.
shear wave velocity of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: At 6 months after Anterior Cruciate Ligament reconstruction.
shear wave velocity of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: At 12 months after Anterior Cruciate Ligament reconstruction.
shear wave velocity of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
Measured: At 24 months after Anterior Cruciate Ligament reconstruction.
torque of hip, knee and ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 24 months after Anterior Cruciate Ligament reconstruction.
torque of hip, knee and ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: On the day of enrollment.
torque of hip, knee and ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 3 months after Anterior Cruciate Ligament reconstruction.
torque of hip, knee and ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 6 months after Anterior Cruciate Ligament reconstruction.
torque of hip, knee and ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 12 months after Anterior Cruciate Ligament reconstruction.
angle of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: On the day of enrollment.
angle of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 3 months after Anterior Cruciate Ligament reconstruction.
angle of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 6 months after Anterior Cruciate Ligament reconstruction.
angle of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 12 months after Anterior Cruciate Ligament reconstruction.
angle of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 24 months after Anterior Cruciate Ligament reconstruction.
angle of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: On the day of enrollment.
angle of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 3 months after Anterior Cruciate Ligament reconstruction.
angle of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 6 months after Anterior Cruciate Ligament reconstruction.
angle of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 12 months after Anterior Cruciate Ligament reconstruction.
angle of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 24 months after Anterior Cruciate Ligament reconstruction.
torque of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: On the day of enrollment.
torque of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 3 months after Anterior Cruciate Ligament reconstruction.
torque of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 6 months after Anterior Cruciate Ligament reconstruction.
torque of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 12 months after Anterior Cruciate Ligament reconstruction.
torque of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 24 months after Anterior Cruciate Ligament reconstruction.
torque of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: On the day of enrollment.
torque of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 3 months after Anterior Cruciate Ligament reconstruction.
torque of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 6 months after Anterior Cruciate Ligament reconstruction.
torque of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 12 months after Anterior Cruciate Ligament reconstruction.
torque of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
Measured: At 24 months after Anterior Cruciate Ligament reconstruction.
Secondary outcomes (1)
The International Knee Documentation Committee (IKDC) score
The International Knee Documentation Committee (IKDC) score was used to evaluate the knee health.The patients completed score by themselves. The lowest score is 0 and the highest score is 100.
Measured: On the day of enrollment, at 3 months, 6 months, 12 months after operation and 24 months after Anterior Cruciate Ligament reconstruction.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Jul 2021
- Study start2 Feb 2018
- Primary completion8 Jan 2020
- Study completion31 Dec 2022 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Anterior Cruciate Ligament InjuriesStudies of the same condition, open and under way.
- More trials run by Peking University Third HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 110 participants (actual)
Sponsor and investigators
- Lead sponsor
- Peking University Third Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Hongshi Huang, Doctor, Study chair, Peking University Third Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04961736
- Sponsor's protocol ID
- OR005
- Status last verified
- Jul 2020
- First submitted
- 29 Jun 2020
- Last updated
- 14 Jul 2021
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 14 Jul 2021. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Ultrasound Evaluation of Hamstring Tendon Regeneration After Anterior Cruciate Ligament Reconstruction and Its Influence on Gait Touch Information
- ClinicalTrials.gov ID
- NCT04961736
- Acronym / sponsor ID
- OR005
- Conditions
- Anterior Cruciate Ligament Injuries
- Keywords
- anterior cruciate ligament, gait analysis, plantar pressure, Ultrasound evaluation
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 110 participants (actual)
- Lead sponsor
- Peking University Third HospitalUniversity, hospital or other
- Study start
- 2 Feb 2018 (actual)
- Primary completion
- 8 Jan 2020 (actual)
- Study completion
- 31 Dec 2022 (estimated)
- First posted
- 14 Jul 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
High incidence rate of knee osteoarthritis and gait analysis are important for early assessment of biomechanics. ACL injury is an ideal clinical model for studying knee osteoarthritis.
To clarify the mechanism between the biomechanical status of knee joint and the change of gait touch information, and to provide scientific basis for quantifying and evaluating the biomechanical status of knee joint in dynamic load-bearing state.
Detailed description
Objective: to analyze the shape and function of the regenerated hamstring tendon within 2 years after the removal of the hamstring tendon in ACL reconstruction, reveal the change rule of the characteristics of hamstring tendon regeneration and its biomechanical changes, and guide the selection of operation and postoperative rehabilitation.
Methods: 55 healthy people and 55 male patients with ACL reconstruction were recruited. All completed the basic rehabilitation training under the guidance of the postoperative rehabilitation program. Using infrared motion capture system, three-dimensional force measuring platform, isokinetic muscle force testing system and ultrasound, the anterior cruciate ligament reconstruction patients were tested before operation, 2 weeks, 3 months, 6 months, 12 months after operation and 24 months after operation.
Outcome evaluation indicators and statistical methods: evaluation indicators: (1) three dimensional motion capture and analysis results: 1) peak ground reaction force; 2) three-dimensional angle and torque of hip, knee and ankle joints in different stages; (2) isokinetic muscle strength results: bilateral knee extension torque and knee flexion torque at different angles and angular velocities. (3)Ultrasound evaluation: the thickness, cross-sectional area and shear wave velocity of the semitendinosus were measured.
Statistical methods: ① repeated measurement analysis of variance (ANOVA) was used to test the effects of different time after operation on the three-dimensional gait characteristics, muscle strength and tendon regeneration characteristics. ② Independent sample t-test was used to test the three-dimensional characteristics, muscle strength and tendon condition of patients at different time points after operation. ③ The difference of three-dimensional gait characteristics, muscle strength and tendon between the healthy side and the affected side at different time points after operation were examined by paired sample t-test. ④ Bivariate correlation analysis was used to analyze whether the thickness, cross-sectional area, shear wave propagation velocity and postoperative time were related.
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Anterior Cruciate Ligament injury and reconstruction group | – | Other: no interventionAccording to the previous clinical diagnosis, volunteers who has never suffered the Anterior Cruciate Ligament injury. |
| normal control group | – | Other: no interventionAccording to the previous clinical diagnosis, volunteers who has never suffered the lower extremity sports injuries. |
Who may qualify
- Ages
- 18 to 35 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- Inclusion criteria: Age: 18-35 years old. Patients who have isolated ACL injury and receive ACL reconstruction surgery at Peking University Third Hospital. With isolated ACL injury (an ACL injury with no need for surgical repairs to other knee structures). All participants have no known disorders or diseases other than ACL rupture. Exclusion criteria: Female patients who are pregnant, or suspected pregnant, or in breastfeeding will be excluded from this study.
Key inclusion criteria (4 listed)
- 18-35 years old
- Patients who have isolated ACL injury and receive ACL reconstruction surgery at Peking University Third Hospital.
- With isolated ACL injury (an ACL injury with no need for surgical repairs to other knee structures).
- All participants have no known disorders or diseases other than ACL rupture.
Key exclusion criteria (1 listed)
- Female patients who are pregnant, or suspected pregnant, or in breastfeeding will be excluded from this study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| no interventionThis is an observation study, with no intervention | Other | Anterior Cruciate Ligament injury and reconstruction group, normal control group |
Primary outcome
peak ground reaction force
Time frame: On the day of enrollment.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
peak ground reaction force
Time frame: At 3 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
peak ground reaction force
Time frame: At 6 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
peak ground reaction force
Time frame: At 12 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
peak ground reaction force
Time frame: At 24 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angle of hip in different stages
Time frame: At 24 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angle of hip in different stages
Time frame: On the day of enrollment.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angle of hip in different stages
Time frame: At 3 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angle of hip in different stages
Time frame: At 6 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angle of hip in different stages
Time frame: At 12 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
bilateral knee extension torque
Time frame: On the day of enrollment.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
bilateral knee extension torque
Time frame: At 3 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
bilateral knee extension torque
Time frame: At 6 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
bilateral knee extension torque
Time frame: At 12 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
bilateral knee extension torque
Time frame: At 24 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
knee flexion torque at different angles
Time frame: On the day of enrollment.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
knee flexion torque at different angles
Time frame: At 3 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
knee flexion torque at different angles
Time frame: At 6 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
knee flexion torque at different angles
Time frame: At 12 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
knee flexion torque at different angles
Time frame: At 24 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angular velocities
Time frame: On the day of enrollment.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angular velocities
Time frame: At 3 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angular velocities
Time frame: At 6 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angular velocities
Time frame: At 12 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angular velocities
Time frame: At 24 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
the thickness of the semitendinosus
Time frame: On the day of enrollment.
Ultrasound evaluation was made by Ultrasonic detector.
the cross-sectional area of the semitendinosus
Time frame: On the day of enrollment.
Ultrasound evaluation was made by Ultrasonic detector.
the thickness of the semitendinosus
Time frame: At 2 weeks after Anterior Cruciate Ligament reconstruction.
Ultrasound evaluation was made by Ultrasonic detector.
the cross-sectional area of the semitendinosus
Time frame: At 2 weeks after Anterior Cruciate Ligament reconstruction.
Ultrasound evaluation was made by Ultrasonic detector.
the thickness of the semitendinosus
Time frame: At 3 months after Anterior Cruciate Ligament reconstruction.
Ultrasound evaluation was made by Ultrasonic detector.
the cross-sectional area of the semitendinosus
Time frame: At 3 months after Anterior Cruciate Ligament reconstruction.
Ultrasound evaluation was made by Ultrasonic detector.
the thickness of the semitendinosus
Time frame: At 6 months after Anterior Cruciate Ligament reconstruction.
Ultrasound evaluation was made by Ultrasonic detector.
the cross-sectional area of the semitendinosus
Time frame: At 6 months after Anterior Cruciate Ligament reconstruction.
Ultrasound evaluation was made by Ultrasonic detector.
the thickness of the semitendinosus
Time frame: At 12 months after Anterior Cruciate Ligament reconstruction.
Ultrasound evaluation was made by Ultrasonic detector.
the cross-sectional area of the semitendinosus
Time frame: At 12 months after Anterior Cruciate Ligament reconstruction.
Ultrasound evaluation was made by Ultrasonic detector.
the thickness of the semitendinosus
Time frame: At 24 months after Anterior Cruciate Ligament reconstruction.
Ultrasound evaluation was made by Ultrasonic detector.
the cross-sectional area of the semitendinosus
Time frame: At 24 months after Anterior Cruciate Ligament reconstruction.
Ultrasound evaluation was made by Ultrasonic detector.
shear wave velocity of the semitendinosus
Time frame: On the day of enrollment.
Ultrasound evaluation was made by Ultrasonic detector.
shear wave velocity of the semitendinosus
Time frame: At 3 months after Anterior Cruciate Ligament reconstruction.
Ultrasound evaluation was made by Ultrasonic detector.
shear wave velocity of the semitendinosus
Time frame: At 6 months after Anterior Cruciate Ligament reconstruction.
Ultrasound evaluation was made by Ultrasonic detector.
shear wave velocity of the semitendinosus
Time frame: At 12 months after Anterior Cruciate Ligament reconstruction.
Ultrasound evaluation was made by Ultrasonic detector.
shear wave velocity of the semitendinosus
Time frame: At 24 months after Anterior Cruciate Ligament reconstruction.
Ultrasound evaluation was made by Ultrasonic detector.
torque of hip, knee and ankle joints in different stages
Time frame: At 24 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
torque of hip, knee and ankle joints in different stages
Time frame: On the day of enrollment.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
torque of hip, knee and ankle joints in different stages
Time frame: At 3 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
torque of hip, knee and ankle joints in different stages
Time frame: At 6 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
torque of hip, knee and ankle joints in different stages
Time frame: At 12 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angle of knee joints in different stages
Time frame: On the day of enrollment.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angle of knee joints in different stages
Time frame: At 3 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angle of knee joints in different stages
Time frame: At 6 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angle of knee joints in different stages
Time frame: At 12 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angle of knee joints in different stages
Time frame: At 24 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angle of ankle joints in different stages
Time frame: On the day of enrollment.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angle of ankle joints in different stages
Time frame: At 3 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angle of ankle joints in different stages
Time frame: At 6 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angle of ankle joints in different stages
Time frame: At 12 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
angle of ankle joints in different stages
Time frame: At 24 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
torque of knee joints in different stages
Time frame: On the day of enrollment.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
torque of knee joints in different stages
Time frame: At 3 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
torque of knee joints in different stages
Time frame: At 6 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
torque of knee joints in different stages
Time frame: At 12 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
torque of knee joints in different stages
Time frame: At 24 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
torque of ankle joints in different stages
Time frame: On the day of enrollment.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
torque of ankle joints in different stages
Time frame: At 3 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
torque of ankle joints in different stages
Time frame: At 6 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
torque of ankle joints in different stages
Time frame: At 12 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
torque of ankle joints in different stages
Time frame: At 24 months after Anterior Cruciate Ligament reconstruction.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
1 secondary outcome
The International Knee Documentation Committee (IKDC) score
Time frame: On the day of enrollment, at 3 months, 6 months, 12 months after operation and 24 months after Anterior Cruciate Ligament reconstruction.
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Jul 2021.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Hongshi Huang, Doctor study chair
Peking University Third Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Anterior Cruciate Ligament Injuries, run by Peking University Third Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 14 Jul 2021. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
peak ground reaction force (time frame: On the day of enrollment.). The study lists 67 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Jul 2021.