Opioid Use, UnspecifiedNCT04252443
Nurses' Knowledge and Attitude About Opioids
A study testing Evaluation of nurses' knowledge and attitudes about opioid analgesics working in a university hospital in people with Opioid Use, Unspecified and Nurse's Role, run by European University of Lefke at 1 site in Turkey (Türkiye).
Trial summary
Opioid analgesics used in moderate or severe pain have potential side effects and addiction. Therefore, nurses have hesitations about opioid administration.This descriptive study aimed to evaluate the attitude and knowledge of nurses working in a university hospital about opioids. Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Opioid Use, Unspecified, Nurse's Role, Knowledge, Attitudes, Practice
- What is being tested?
- Evaluation of nurses' knowledge and attitudes about opioid analgesics working in a university hospital
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 127 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jun 2018to 5 Jun 2018
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
None listed.
Who cannot join
- Other health care personnel, did not accept to join to study, long term leaving from job
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Nurses' Knowledge and Attitudes Towards Opioids in Pain Management in North Cyprus
Opioid analgesics used in moderate or severe pain have potential side effects and addiction. Therefore, nurses have hesitations about opioid administration.This descriptive study aimed to evaluate the attitude and knowledge of nurses working in a university hospital about opioids. One hundred twenty-seven nurses were interviewed in the research population. The research data were obtained from the questionnaire, prepared by the researchers, between 01-05 June 2018. It consisted of three parts: descriptive characteristics, attitudes, and knowledge on opioid administration, and evaluation of basic nursing skills and pharmacology about opioids. Statistical Package for Social Sciences (SPSS) 24.0 package program was used for statistical analysis.
Read the detailed description
Analgesics do not eliminate the cause of pain but reduce or eliminate that feeling. Non-steroid analgesics are preferred in mild and moderate, and opioids are used to moderate or severe pain that does not respond to anti-inflammatory agents. However, nurses avoid the administration of opioids because of side effects and addiction risk.The first step in the effectiveness of pain management in the emergency department is evaluation and control. Pain control should be included in the emergency management system from the stage of triage assessment of the patient and should be concluded with the correct analgesic use, if necessary. In emergency departments, waiting for analgesia can be prolonged unnecessarily, and mostly insufficient doses of analgesics administered.Mainly the use of opioids in the emergency department is not preferred much because it reduces the symptoms and masks the examination findings. However, against this conventional idea, recent studies have shown that opioids use reduces pain-related anxiety.Also, it increases the patients' participation in the examination, thus making it more effective. While patients feel better, symptoms such as tenderness and defense were generally not affected by analgesia.This descriptive study was conducted to evaluate the attitude and knowledge of nurses working in a university hospital about opioid analgesic administration, after the ethical committee approved.
- Being tested
- Evaluation of nurses' knowledge and attitudes about opioid analgesics working in a university hospital
- Keywords
- Opioid, Knowledge, Attitude, Nursing
- Medical subject headings
- Behavior
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Evaluation of nurses' knowledge and attitudes about opioid analgesics working in a university hospitalOther
Also called Knowledge about opioid and adjuvant analgesics, Opinions and attitudes on opioid administration
Interventions involving nurses' pharmacological level
| Study group | Role | What they receive |
|---|---|---|
| Nurse | Other | The research population consisted of 190 nurses working in a university hospital. Because all of the nurses in the research population could not be reached, a sample was selected using a simple random sampling method. One hundred twenty-seven nurses were interviewed in the research population, with a 95% confidence interval and a 5% sampling error. Receives: Other: Evaluation of nurses' knowledge and attitudes about opioid analgesics working in a university hospital |
What is being measured
The primary outcome is the main question the study is designed to answer.
Nurses' Knowledge and Attitudes towards Opioids in Pain Management in North Cyprus
Questionnaire, Knowledge scores of the participants were calculated over 100. 4 points were given for each correct answer, and 0 for each wrong or "don't know. " The range of scores was 0-100. A high score was a mean high level of knowledge.
Measured: Through study completion, an average of 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Feb 2020
- Study start1 Jun 2018
- Primary completion5 Jun 2018
- Study completion5 Jun 2018
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (23)Papers the sponsor has linked to this study.
- Other trials for Opioid Use, UnspecifiedStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- The research population consisted of 190 nurses working in a university hospital. Because all of the nurses in the research population could not be reached, a sample was selected using a simple random sampling method. One hundred twenty-seven nurses were interviewed in the research population, with a 95% confidence interval and a 5% sampling error.
- Masking
- None (open label)
- Enrolment
- 127 participants (actual)
Sponsor and investigators
- Lead sponsor
- European University of Lefke
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Semra Aslay, European University of Lefke
- Investigators
- Semra Aslay, MD, Study director, European University of Lefke
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04252443
- Sponsor's protocol ID
- opioid
- Status last verified
- Jan 2020
- First submitted
- 29 Jan 2020
- Last updated
- 5 Feb 2020
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: All collected individual participating data
Publications
Abdolrazaghnejad A, Banaie M, Tavakoli N, Safdari M, Rajabpour-Sanati A. Pain Management in the Emergency Department: a Review Article on Options and Methods. Adv J Emerg Med. 2018 Jun 24;2(4):e45. doi: 10.22114/AJEM.v0i0.93. eCollection 2018 Fall.
PubMed 31172108Reagan KML, O'Sullivan DM, Gannon R, Steinberg AC. Decreasing postoperative narcotics in reconstructive pelvic surgery: a randomized controlled trial. Am J Obstet Gynecol. 2017 Sep;217(3):325.e1-325.e10. doi: 10.1016/j.ajog.2017.05.041. Epub 2017 May 25.
PubMed 28551445Janati M, Kariman H, Memary E, Davarinezhad-Moghadam E, Arhami-Dolatabadi A. Educational Intervention Effect on Pain Management Quality in Emergency Department; a Clinical Audit. Adv J Emerg Med. 2018 Jan 16;2(2):e16. doi: 10.22114/AJEM.v0i0.45. eCollection 2018 Spring.
PubMed 31172079Fein JA, Zempsky WT, Cravero JP; Committee on Pediatric Emergency Medicine and Section on Anesthesiology and Pain Medicine; American Academy of Pediatrics. Relief of pain and anxiety in pediatric patients in emergency medical systems. Pediatrics. 2012 Nov;130(5):e1391-405. doi: 10.1542/peds.2012-2536. Epub 2012 Oct 29.
PubMed 23109683Chou R, Gordon DB, de Leon-Casasola OA, Rosenberg JM, Bickler S, Brennan T, Carter T, Cassidy CL, Chittenden EH, Degenhardt E, Griffith S, Manworren R, McCarberg B, Montgomery R, Murphy J, Perkal MF, Suresh S, Sluka K, Strassels S, Thirlby R, Viscusi E, Walco GA, Warner L, Weisman SJ, Wu CL. Management of Postoperative Pain: A Clinical Practice Guideline From the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists' Committee on Regional Anesthesia, Executive Committee, and Administrative Council. J Pain. 2016 Feb;17(2):131-57. doi: 10.1016/j.jpain.2015.12.008.
PubMed 26827847Costello M, Thompson S. Preventing Opioid Misuse and Potential Abuse: The Nurse's Role in Patient Education. Pain Manag Nurs. 2015 Aug;16(4):515-9. doi: 10.1016/j.pmn.2014.09.008. Epub 2014 Dec 8.
PubMed 25497402Hunold KM, Esserman DA, Isaacs CG, Dickey RM, Pereira GF, Fillingim RB, Sloane PD, McLean SA, Platts-Mills TF. Side effects from oral opioids in older adults during the first week of treatment for acute musculoskeletal pain. Acad Emerg Med. 2013 Sep;20(9):872-9. doi: 10.1111/acem.12212. Epub 2013 Aug 27.
PubMed 24033733Trescot AM, Helm S, Hansen H, Benyamin R, Glaser SE, Adlaka R, Patel S, Manchikanti L. Opioids in the management of chronic non-cancer pain: an update of American Society of the Interventional Pain Physicians' (ASIPP) Guidelines. Pain Physician. 2008 Mar;11(2 Suppl):S5-S62.
PubMed 18443640Chapman CR, Lipschitz DL, Angst MS, Chou R, Denisco RC, Donaldson GW, Fine PG, Foley KM, Gallagher RM, Gilson AM, Haddox JD, Horn SD, Inturrisi CE, Jick SS, Lipman AG, Loeser JD, Noble M, Porter L, Rowbotham MC, Schoelles KM, Turk DC, Volinn E, Von Korff MR, Webster LR, Weisner CM. Opioid pharmacotherapy for chronic non-cancer pain in the United States: a research guideline for developing an evidence-base. J Pain. 2010 Sep;11(9):807-29. doi: 10.1016/j.jpain.2010.02.019. Epub 2010 Apr 28.
PubMed 20430701Gomes T, Tadrous M, Mamdani MM, Paterson JM, Juurlink DN. The Burden of Opioid-Related Mortality in the United States. JAMA Netw Open. 2018 Jun 1;1(2):e180217. doi: 10.1001/jamanetworkopen.2018.0217.
PubMed 30646062Hsaio GY, Chen IJ, Yu S, Wei IL, Fang YY, Tang FI. Nurses' knowledge of high-alert medications: instrument development and validation. J Adv Nurs. 2010 Jan;66(1):177-90. doi: 10.1111/j.1365-2648.2009.05164.x.
PubMed 20423443Samarkandi OA. Knowledge and attitudes of nurses toward pain management. Saudi J Anaesth. 2018 Apr-Jun;12(2):220-226. doi: 10.4103/sja.SJA_587_17.
PubMed 29628831de Freitas GR, de Castro CG Jr, Castro SM, Heineck I. Degree of knowledge of health care professionals about pain management and use of opioids in pediatrics. Pain Med. 2014 May;15(5):807-19. doi: 10.1111/pme.12332. Epub 2014 Jan 8.
PubMed 24401078Gorawara-Bhat R, Wong A, Dale W, Hogan T. Nurses' perceptions of pain management for older-patients in the Emergency Department: A qualitative study. Patient Educ Couns. 2017 Feb;100(2):231-241. doi: 10.1016/j.pec.2016.08.019. Epub 2016 Aug 29.
PubMed 27591825Charalambous A, Zorpas M, Cloconi C, Kading Y. Healthcare professionals' perceptions on the use of opioid analgesics for the treatment of cancer-related pain in Cyprus: A mixed-method study. SAGE Open Med. 2019 Apr 4;7:2050312119841823. doi: 10.1177/2050312119841823. eCollection 2019.
PubMed 31057793
Study at a glance
From the registry record, last updated by the sponsor on 5 Feb 2020. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Nurses' Knowledge and Attitudes Towards Opioids in Pain Management in North Cyprus
- ClinicalTrials.gov ID
- NCT04252443
- Acronym / sponsor ID
- opioid
- Keywords
- Opioid, Knowledge, Attitude, Nursing
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 127 participants (actual)
- Lead sponsor
- European University of LefkeUniversity, hospital or other
- Study start
- 1 Jun 2018 (actual)
- Primary completion
- 5 Jun 2018 (actual)
- Study completion
- 5 Jun 2018 (actual)
- First posted
- 5 Feb 2020 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Opioid analgesics used in moderate or severe pain have potential side effects and addiction. Therefore, nurses have hesitations about opioid administration.This descriptive study aimed to evaluate the attitude and knowledge of nurses working in a university hospital about opioids. One hundred twenty-seven nurses were interviewed in the research population. The research data were obtained from the questionnaire, prepared by the researchers, between 01-05 June 2018. It consisted of three parts: descriptive characteristics, attitudes, and knowledge on opioid administration, and evaluation of basic nursing skills and pharmacology about opioids. Statistical Package for Social Sciences (SPSS) 24.0 package program was used for statistical analysis.
Detailed description
Analgesics do not eliminate the cause of pain but reduce or eliminate that feeling. Non-steroid analgesics are preferred in mild and moderate, and opioids are used to moderate or severe pain that does not respond to anti-inflammatory agents. However, nurses avoid the administration of opioids because of side effects and addiction risk.The first step in the effectiveness of pain management in the emergency department is evaluation and control. Pain control should be included in the emergency management system from the stage of triage assessment of the patient and should be concluded with the correct analgesic use, if necessary. In emergency departments, waiting for analgesia can be prolonged unnecessarily, and mostly insufficient doses of analgesics administered.Mainly the use of opioids in the emergency department is not preferred much because it reduces the symptoms and masks the examination findings. However, against this conventional idea, recent studies have shown that opioids use reduces pain-related anxiety.Also, it increases the patients' participation in the examination, thus making it more effective. While patients feel better, symptoms such as tenderness and defense were generally not affected by analgesia.This descriptive study was conducted to evaluate the attitude and knowledge of nurses working in a university hospital about opioid analgesic administration, after the ethical committee approved.
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- The research population consisted of 190 nurses working in a university hospital. Because all of the nurses in the research population could not be reached, a sample was selected using a simple random sampling method. One hundred twenty-seven nurses were interviewed in the research population, with a 95% confidence interval and a 5% sampling error.
| Arm | Type | Receives |
|---|---|---|
| Nurse | Other | Other: Evaluation of nurses' knowledge and attitudes about opioid analgesics working in a university hospitalThe research population consisted of 190 nurses working in a university hospital. Because all of the nurses in the research population could not be reached, a sample was selected using a simple random sampling method. One hundred twenty-seven nurses were interviewed in the research population, with a 95% confidence interval and a 5% sampling error. |
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (0 listed)
Key exclusion criteria (1 listed)
- Other health care personnel, did not accept to join to study, long term leaving from job
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Evaluation of nurses' knowledge and attitudes about opioid analgesics working in a university hospitalAlso: Knowledge about opioid and adjuvant analgesics, Opinions and attitudes on opioid administrationInterventions involving nurses' pharmacological level | Other | Nurse |
Primary outcome
Nurses' Knowledge and Attitudes towards Opioids in Pain Management in North Cyprus
Time frame: Through study completion, an average of 6 months
Questionnaire, Knowledge scores of the participants were calculated over 100. 4 points were given for each correct answer, and 0 for each wrong or "don't know. " The range of scores was 0-100. A high score was a mean high level of knowledge.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Feb 2020.
- Background: PubMed 31172108Abdolrazaghnejad A, Banaie M, Tavakoli N, Safdari M, Rajabpour-Sanati A. Pain Management in the Emergency Department: a Review Article on Options and Methods. Adv J Emerg Med. 2018 Jun 24;2(4):e45. doi: 10.22114/AJEM.v0i0.93. eCollection 2018 Fall.
- Background: PubMed 28551445Reagan KML, O'Sullivan DM, Gannon R, Steinberg AC. Decreasing postoperative narcotics in reconstructive pelvic surgery: a randomized controlled trial. Am J Obstet Gynecol. 2017 Sep;217(3):325.e1-325.e10. doi: 10.1016/j.ajog.2017.05.041. Epub 2017 May 25.
- Background: PubMed 31172079Janati M, Kariman H, Memary E, Davarinezhad-Moghadam E, Arhami-Dolatabadi A. Educational Intervention Effect on Pain Management Quality in Emergency Department; a Clinical Audit. Adv J Emerg Med. 2018 Jan 16;2(2):e16. doi: 10.22114/AJEM.v0i0.45. eCollection 2018 Spring.
- Background: PubMed 23109683Fein JA, Zempsky WT, Cravero JP; Committee on Pediatric Emergency Medicine and Section on Anesthesiology and Pain Medicine; American Academy of Pediatrics. Relief of pain and anxiety in pediatric patients in emergency medical systems. Pediatrics. 2012 Nov;130(5):e1391-405. doi: 10.1542/peds.2012-2536. Epub 2012 Oct 29.
- Background: PubMed 26827847Chou R, Gordon DB, de Leon-Casasola OA, Rosenberg JM, Bickler S, Brennan T, Carter T, Cassidy CL, Chittenden EH, Degenhardt E, Griffith S, Manworren R, McCarberg B, Montgomery R, Murphy J, Perkal MF, Suresh S, Sluka K, Strassels S, Thirlby R, Viscusi E, Walco GA, Warner L, Weisman SJ, Wu CL. Management of Postoperative Pain: A Clinical Practice Guideline From the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists' Committee on Regional Anesthesia, Executive Committee, and Administrative Council. J Pain. 2016 Feb;17(2):131-57. doi: 10.1016/j.jpain.2015.12.008.
- Background: PubMed 25497402Costello M, Thompson S. Preventing Opioid Misuse and Potential Abuse: The Nurse's Role in Patient Education. Pain Manag Nurs. 2015 Aug;16(4):515-9. doi: 10.1016/j.pmn.2014.09.008. Epub 2014 Dec 8.
- Background: PubMed 24033733Hunold KM, Esserman DA, Isaacs CG, Dickey RM, Pereira GF, Fillingim RB, Sloane PD, McLean SA, Platts-Mills TF. Side effects from oral opioids in older adults during the first week of treatment for acute musculoskeletal pain. Acad Emerg Med. 2013 Sep;20(9):872-9. doi: 10.1111/acem.12212. Epub 2013 Aug 27.
- Background: PubMed 18443640Trescot AM, Helm S, Hansen H, Benyamin R, Glaser SE, Adlaka R, Patel S, Manchikanti L. Opioids in the management of chronic non-cancer pain: an update of American Society of the Interventional Pain Physicians' (ASIPP) Guidelines. Pain Physician. 2008 Mar;11(2 Suppl):S5-S62.
- Background: PubMed 20430701Chapman CR, Lipschitz DL, Angst MS, Chou R, Denisco RC, Donaldson GW, Fine PG, Foley KM, Gallagher RM, Gilson AM, Haddox JD, Horn SD, Inturrisi CE, Jick SS, Lipman AG, Loeser JD, Noble M, Porter L, Rowbotham MC, Schoelles KM, Turk DC, Volinn E, Von Korff MR, Webster LR, Weisner CM. Opioid pharmacotherapy for chronic non-cancer pain in the United States: a research guideline for developing an evidence-base. J Pain. 2010 Sep;11(9):807-29. doi: 10.1016/j.jpain.2010.02.019. Epub 2010 Apr 28.
- Background: PubMed 30646062Gomes T, Tadrous M, Mamdani MM, Paterson JM, Juurlink DN. The Burden of Opioid-Related Mortality in the United States. JAMA Netw Open. 2018 Jun 1;1(2):e180217. doi: 10.1001/jamanetworkopen.2018.0217.
- Background: PubMed 20423443Hsaio GY, Chen IJ, Yu S, Wei IL, Fang YY, Tang FI. Nurses' knowledge of high-alert medications: instrument development and validation. J Adv Nurs. 2010 Jan;66(1):177-90. doi: 10.1111/j.1365-2648.2009.05164.x.
- Background: PubMed 29628831Samarkandi OA. Knowledge and attitudes of nurses toward pain management. Saudi J Anaesth. 2018 Apr-Jun;12(2):220-226. doi: 10.4103/sja.SJA_587_17.
- World Health Organization Analgesic Ladder SchemeLink provided by the sponsor.
- Individual participant dataSharing planned: Yes. All collected individual participating data
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Semra Aslay, MD study director
European University of Lefke
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Evaluation of nurses' knowledge and attitudes about opioid analgesics working in a university hospital in people with Opioid Use, Unspecified and Nurse's Role, run by European University of Lefke at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 0 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 Feb 2020. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Nurses' Knowledge and Attitudes towards Opioids in Pain Management in North Cyprus (time frame: Through study completion, an average of 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04252443, which also lists 23 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Feb 2020.