Pulmonary Artery StenosisSEGPULNCT03628326
Evaluation of Visceral Pleural Lumbar Lymphatic Drainage
An observational study of Pulmonary Artery Stenosis, run by Centre Hospitalier Universitaire, Amiens at 1 site in France.
Trial summary
Anatomic variations of the pulmonary arterial tree can cause technical difficulties during pulmonary lobectomy in general and video-assisted thoracic surgery (VATS). Using CT angiography and 3D reconstruction, the investigators sought to identify anatomic variations of the pulmonary arterial tree and assess their… Read more about this study
- Who is it for?
- Ages 50 to 75 years
- Conditions the study is for
- Pulmonary Artery Stenosis
- What is being tested?
- Pulmonary arterial tree
- How many people
- 44 participants
- Where
- 1 siteFrance
- Study dates
- 1 Apr 2016to 1 Aug 2017
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 to 75 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: The investigators studied patients having undergone VATS lobectomy for stage I-II lung cancer at the Amiens University Hospital's Department of Thoracic Surgery between October 2012 and March 2014. We performed 3D reconstruction of the pulmonary arterial tree on the CT angiography data set acquired during preoperative work-up.
Who may be able to join
- Any major patient aged 18 years and over who has undergone oncological lung lobectomy for non-small-cell lung cancer located in the thoracic surgery department of the University Hospital of Amiens.
- Nosologic criteria and related to acts: The pathology has already been diagnosed or suspected, and the surgical indication has been validated in the Multidisciplinary Thoracic Oncology Concertation Meeting according to national recommendations.
- These patients will be collected in a database already referenced in the register of the establishment of the University Hospital of Amiens under the reference DRCI T38
Who cannot join
- Criteria relating to the population:
- Patient under guardianship or curatorship
- Pathology Criteria: Patient with no pulmonary neoplastic disease, patient with locally advanced or metastatic bronchopulmonary cancer
- Criteria relating to the acts: the criteria altering the surgical specimen and thus its anatomical study: patient having had an extemporaneous examination, patient with the antecedents of ipsilateral pulmonary surgery and / or need of decortication
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Is Pulmonary Segmentectomy an Anatomical Resection? Evaluation of Visceral Pleural Lumbar Lymphatic Drainage - Anatomo-clinical Correlation.
Anatomic variations of the pulmonary arterial tree can cause technical difficulties during pulmonary lobectomy in general and video-assisted thoracic surgery (VATS). Using CT angiography and 3D reconstruction, the investigators sought to identify anatomic variations of the pulmonary arterial tree and assess their respective frequencies.
Read the detailed description
Purpose Anatomic variations of the pulmonary arterial tree can cause technical difficulties during pulmonary lobectomy in general and video-assisted thoracic surgery (VATS). Using CT angiography and 3D reconstruction, the investigators sought to identify anatomic variations of the pulmonary arterial tree and assess their respective frequencies. Methods the investigators retrospectively studied 88 pulmonary arterial trees in 44 patients having undergone VATS lobectomy for lung cancer over an 18-month period in Amiens University Hospital's Department of Thoracic Surgery. Each CT angiography with 3D reconstruction of the pulmonary arterial tree was performed by two experienced operators, according to a standardized procedure.
- Conditions
- Pulmonary Artery Stenosis
- Being tested
- Pulmonary arterial tree
- Keywords
- Pulmonary artery, 3D reconstruction, Video-assisted thoracic surgery lobectomy, CT angiography, Anatomic variation
- Medical subject headings
- Stenosis, Pulmonary Artery
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Pulmonary arterial treeOther
The investigators performed 3D reconstruction of the pulmonary arterial tree on the CT angiography data set acquired during preoperative work-up.
| Study group | Role | What they receive |
|---|---|---|
| right lung resection | The investigators sought to identify anatomic variations of the pulmonary arterial tree and assess their respective frequencies. Receives: Other: Pulmonary arterial tree | |
| left lung resection | The investigators sought to identify anatomic variations of the pulmonary arterial tree and assess their respective frequencies. Receives: Other: Pulmonary arterial tree |
What is being measured
The primary outcome is the main question the study is designed to answer.
Use CT angiography and 3D reconstruction
The primary objective of the present study was to use CT angiography and 3D reconstruction to assess the pulmonary arterial tree and its anatomic variations in patients having undergone VATS lobectomy for stage I-II lung cancer. The investigators studied patients having undergone VATS lobectomy for stage I-II lung cancer at the Amiens University Hospital's Department of Thoracic Surgery between October 2012 and March 2014. The investigators performed 3D reconstruction of the pulmonary arterial tree on the CT angiography data set acquired during preoperative work-up. Patients having undergone CT angiography in another hospital, those not having undergone CT angiography of the arterial tree, and those having been operated on more than once for lung cancer were excluded from the study.
Measured: 18-month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Aug 2018
- Study start1 Apr 2016
- Primary completion1 Aug 2017
- Study completion1 Aug 2017
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Pulmonary Artery StenosisStudies of the same condition, open and under way.
- More trials run by Centre Hospitalier Universitaire, AmiensThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Retrospective
- Enrolment
- 44 participants (actual)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Universitaire, Amiens
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Frederic Marçon, MD, Principal investigator, CHU AMIENS
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03628326
- Sponsor's protocol ID
- RNI2016-01
- Acronym
- SEGPUL
- Status last verified
- Jun 2026
- First submitted
- 31 Jul 2018
- Last updated
- 24 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Is Pulmonary Segmentectomy an Anatomical Resection? Evaluation of Visceral Pleural Lumbar Lymphatic Drainage - Anatomo-clinical Correlation.
- ClinicalTrials.gov ID
- NCT03628326
- Acronym / sponsor ID
- SEGPUL / RNI2016-01
- Conditions
- Pulmonary Artery Stenosis
- Keywords
- Pulmonary artery, 3D reconstruction, Video-assisted thoracic surgery lobectomy, CT angiography, Anatomic variation
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 44 participants (actual)
- Lead sponsor
- Centre Hospitalier Universitaire, AmiensUniversity, hospital or other
- Study start
- 1 Apr 2016 (actual)
- Primary completion
- 1 Aug 2017 (actual)
- Study completion
- 1 Aug 2017 (actual)
- First posted
- 14 Aug 2018 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Anatomic variations of the pulmonary arterial tree can cause technical difficulties during pulmonary lobectomy in general and video-assisted thoracic surgery (VATS). Using CT angiography and 3D reconstruction, the investigators sought to identify anatomic variations of the pulmonary arterial tree and assess their respective frequencies.
Detailed description
Purpose Anatomic variations of the pulmonary arterial tree can cause technical difficulties during pulmonary lobectomy in general and video-assisted thoracic surgery (VATS). Using CT angiography and 3D reconstruction, the investigators sought to identify anatomic variations of the pulmonary arterial tree and assess their respective frequencies. Methods the investigators retrospectively studied 88 pulmonary arterial trees in 44 patients having undergone VATS lobectomy for lung cancer over an 18-month period in Amiens University Hospital's Department of Thoracic Surgery. Each CT angiography with 3D reconstruction of the pulmonary arterial tree was performed by two experienced operators, according to a standardized procedure.
Study design
- Observational model
- Case only
- Time perspective
- Retrospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| right lung resection | – | Other: Pulmonary arterial treeThe investigators sought to identify anatomic variations of the pulmonary arterial tree and assess their respective frequencies. |
| left lung resection | – | Other: Pulmonary arterial treeThe investigators sought to identify anatomic variations of the pulmonary arterial tree and assess their respective frequencies. |
Who may qualify
- Ages
- 50 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- The investigators studied patients having undergone VATS lobectomy for stage I-II lung cancer at the Amiens University Hospital's Department of Thoracic Surgery between October 2012 and March 2014. We performed 3D reconstruction of the pulmonary arterial tree on the CT angiography data set acquired during preoperative work-up.
Key inclusion criteria (3 listed)
- Any major patient aged 18 years and over who has undergone oncological lung lobectomy for non-small-cell lung cancer located in the thoracic surgery department of the University Hospital of Amiens.
- Nosologic criteria and related to acts: The pathology has already been diagnosed or suspected, and the surgical indication has been validated in the Multidisciplinary Thoracic Oncology Concertation Meeting according to national recommendations.
- These patients will be collected in a database already referenced in the register of the establishment of the University Hospital of Amiens under the reference DRCI T38
Key exclusion criteria (4 listed)
- Criteria relating to the population:
- Patient under guardianship or curatorship
- Pathology Criteria: Patient with no pulmonary neoplastic disease, patient with locally advanced or metastatic bronchopulmonary cancer
- Criteria relating to the acts: the criteria altering the surgical specimen and thus its anatomical study: patient having had an extemporaneous examination, patient with the antecedents of ipsilateral pulmonary surgery and / or need of decortication
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Pulmonary arterial treeThe investigators performed 3D reconstruction of the pulmonary arterial tree on the CT angiography data set acquired during preoperative work-up. | Other | left lung resection, right lung resection |
Primary outcome
Use CT angiography and 3D reconstruction
Time frame: 18-month
The primary objective of the present study was to use CT angiography and 3D reconstruction to assess the pulmonary arterial tree and its anatomic variations in patients having undergone VATS lobectomy for stage I-II lung cancer. The investigators studied patients having undergone VATS lobectomy for stage I-II lung cancer at the Amiens University Hospital's Department of Thoracic Surgery between October 2012 and March 2014. The investigators performed 3D reconstruction of the pulmonary arterial tree on the CT angiography data set acquired during preoperative work-up. Patients having undergone CT angiography in another hospital, those not having undergone CT angiography of the arterial tree, and those having been operated on more than once for lung cancer were excluded from the study.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Jun 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Frederic Marçon, MD principal investigator
CHU AMIENS
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Pulmonary Artery Stenosis, run by Centre Hospitalier Universitaire, Amiens at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 24 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Use CT angiography and 3D reconstruction (time frame: 18-month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Jun 2026.