Mesenteric PanniculitisMP - CancerNCT03316001
Mesenteric Panniculitis : Review of Consecutive Abdominal MDCT Examinations With a Matched-pair Analysis
An observational study of Mesenteric Panniculitis, run by CHU de Reims.
Trial summary
Mesenteric panniculitis is a benign inflammatory condition that involves the adipose tissue of the intestinal mesentery. Clinical manifestations are uncommon, non specific and atypical. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Mesenteric Panniculitis
- What is being tested?
- Review of multidetector row computed tomography scans
- How many people
- 288 participants
- Where
- No sites listed yet
- Study dates
- Nov 2014to Jul 2015
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients with a CT scan from January to August 2008 for which mesenteric panniculitis was diagnosed
Who may be able to join
- Patients with a CT scan from January to August 2008
- Patients with diagnosis of mesenteric panniculitis on CT scan
Who cannot join
- Patients with disease that may cause mesenteric infiltration
About this study
Mesenteric panniculitis is a benign inflammatory condition that involves the adipose tissue of the intestinal mesentery. Clinical manifestations are uncommon, non specific and atypical. Mesenteric panniculitis is thus most often an incidental finding during an investigation for other reason, mostly on computed tomography scans. The rate of malignancy in patients with mesenteric panniculitis, especially urogenital and gastrointestinal adenocarcinomas or lymphomas, has been reported to be as high, thus suggesting that there may be a relationship between mesenteric panniculitis and progression of an underlying malignancy or the risk of a future malignancy.
Read the detailed description
The aim was:
to estimate the prevalence of mesenteric panniculitis. to study relationship between mesenteric panniculitis and malignancy. to investigate the 5-year outcome of patients with mesenteric panniculitis for the development of malignancy.
- Conditions
- Mesenteric Panniculitis
- Being tested
- Review of multidetector row computed tomography scans
- Medical subject headings
- Panniculitis, Peritoneal
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Review of multidetector row computed tomography scansOther
multidetector row computed tomography scans
| Study group | Role | What they receive |
|---|---|---|
| cases | patients with a CT scan from January to August 2008 for which mesenteric panniculitis was diagnosed Receives: Other: Review of multidetector row computed tomography scans | |
| controls | patients with a CT scan from January to August 2008 for which mesenteric panniculitis wasn't diagnosed and matched by gender and age with "cases" patients Receives: Other: Review of multidetector row computed tomography scans |
What is being measured
The primary outcome is the main question the study is designed to answer.
mesenteric panniculitis
mesenteric panniculitis is identified on the basis on the presence of three of the following 5 signs on CT scan:
- higher attenuation of the fat of the root of the small bowel mesentery,
- a pseudo mass smoothly displacing neighboring structures with a hyperdense pseudocapsule surrounding the mesenteric fat,
- lymph nodes within the fatty pseudo mass and
- a hypodense halo around the nodes and the blood vessels
Measured: Day 0
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Oct 2017
- Study startNov 2014
- Primary completionMar 2015
- Study completionJul 2015
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Mesenteric PanniculitisStudies of the same condition, open and under way.
- More trials run by CHU de ReimsThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Retrospective
- Enrolment
- 288 participants (actual)
Sponsor and investigators
- Lead sponsor
- CHU de Reims
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03316001
- Sponsor's protocol ID
- 2016Ao002
- Acronym
- MP - Cancer
- Status last verified
- Oct 2017
- First submitted
- 17 Oct 2017
- Last updated
- 20 Oct 2017
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Protin-Catteau L, Thiefin G, Barbe C, Jolly D, Soyer P, Hoeffel C. Mesenteric panniculitis: review of consecutive abdominal MDCT examinations with a matched-pair analysis. Acta Radiol. 2016 Dec;57(12):1438-1444. doi: 10.1177/0284185116629829. Epub 2016 Jul 19.
PubMed 26868171
Study at a glance
From the registry record, last updated by the sponsor on 20 Oct 2017. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Mesenteric Panniculitis : Review of Consecutive Abdominal MDCT Examinations With a Matched-pair Analysis
- ClinicalTrials.gov ID
- NCT03316001
- Acronym / sponsor ID
- MP - Cancer / 2016Ao002
- Conditions
- Mesenteric Panniculitis
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 288 participants (actual)
- Lead sponsor
- CHU de ReimsUniversity, hospital or other
- Study start
- Nov 2014 (actual)
- Primary completion
- Mar 2015 (actual)
- Study completion
- Jul 2015 (actual)
- First posted
- 20 Oct 2017 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Mesenteric panniculitis is a benign inflammatory condition that involves the adipose tissue of the intestinal mesentery. Clinical manifestations are uncommon, non specific and atypical. Mesenteric panniculitis is thus most often an incidental finding during an investigation for other reason, mostly on computed tomography scans. The rate of malignancy in patients with mesenteric panniculitis, especially urogenital and gastrointestinal adenocarcinomas or lymphomas, has been reported to be as high, thus suggesting that there may be a relationship between mesenteric panniculitis and progression of an underlying malignancy or the risk of a future malignancy.
Detailed description
The aim was:
to estimate the prevalence of mesenteric panniculitis. to study relationship between mesenteric panniculitis and malignancy. to investigate the 5-year outcome of patients with mesenteric panniculitis for the development of malignancy.
Study design
- Observational model
- Case-control
- Time perspective
- Retrospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| cases | – | Other: Review of multidetector row computed tomography scanspatients with a CT scan from January to August 2008 for which mesenteric panniculitis was diagnosed |
| controls | – | Other: Review of multidetector row computed tomography scanspatients with a CT scan from January to August 2008 for which mesenteric panniculitis wasn't diagnosed and matched by gender and age with "cases" patients |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients with a CT scan from January to August 2008 for which mesenteric panniculitis was diagnosed
Key inclusion criteria (2 listed)
- Patients with a CT scan from January to August 2008
- Patients with diagnosis of mesenteric panniculitis on CT scan
Key exclusion criteria (1 listed)
- Patients with disease that may cause mesenteric infiltration
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Review of multidetector row computed tomography scansmultidetector row computed tomography scans | Other | cases, controls |
Primary outcome
mesenteric panniculitis
Time frame: Day 0
mesenteric panniculitis is identified on the basis on the presence of three of the following 5 signs on CT scan: * higher attenuation of the fat of the root of the small bowel mesentery, * a pseudo mass smoothly displacing neighboring structures with a hyperdense pseudocapsule surrounding the mesenteric fat, * lymph nodes within the fatty pseudo mass and * a hypodense halo around the nodes and the blood vessels
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Oct 2017.
- Background: PubMed 26868171Protin-Catteau L, Thiefin G, Barbe C, Jolly D, Soyer P, Hoeffel C. Mesenteric panniculitis: review of consecutive abdominal MDCT examinations with a matched-pair analysis. Acta Radiol. 2016 Dec;57(12):1438-1444. doi: 10.1177/0284185116629829. Epub 2016 Jul 19.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
An observational study of Mesenteric Panniculitis, run by CHU de Reims.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 20 Oct 2017. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
mesenteric panniculitis (time frame: Day 0). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT03316001, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Oct 2017.