Research institution
CHU de Reims Clinical Trials
Studies where CHU de Reims is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 43Neuromuscular Disease in Post-Intensive Care Syndrome
Feasibility Study on the Use of a Walking Exoskeleton in the Intensive Care Unit
The purpose of this study is to evaluate the feasibility of using a lower-limb exoskeleton in the intensive care unit for early mobilization of participants with intensive care neuromyopathy.
- Trial name
- ExoRea (NCT07907237)
- Testing
- rehabilitation session assisted by an exoskeleton
- Volunteers
- 30 people
- Sponsor
- CHU de Reims
Chronic Obstructive Pulmonary Disease (COPD)
Effect of Exercise Order During Pulmonary Rehabilitation on Muscle Strength in Patients With COPD
Chronic Obstructive Pulmonary Disease (COPD) is a chronic multisystem disease frequently associated with peripheral muscle dysfunction, which is strongly linked to prognosis and survival.
- Trial name
- ISTOR-COPD (NCT07655011)
- Testing
- Pulmonary Rehabilitation - Strength First, Pulmonary Rehabilitation - Endurance First
- Where
- France
- Volunteers
- 138 people
- Sponsor
- CHU de Reims
Ventilator Associated Pneumonia
Ventilator Associated Pneumonia Multiplex PCR for Anti-Infective Regimens
Ventilator-associated pneumonia (VAP) remains one of the main nosocomial infections acquired in the intensive care unit (ICU). VAP is pneumonia occurring 48 hours after intubation.
- Trial name
- VAMPAIR (NCT06554327)
- Testing
- Multiplex PCR
- Where
- France
- Volunteers
- 265 people
- Sponsor
- CHU de Reims
Unruptured Intracranial Aneurysm
MRI Analysis in the Growth of Cerebral Aneurysms
An intracranial aneurysm is defined as a localized dilatation of the cerebral arteries, which can potentially lead to rupture and subsequent hemorrhagic stroke. The mechanisms by which aneurysms develop and grow remain unknown.
- Trial name
- EPICAVC (NCT06705452)
- Testing
- Additional 4D Flow MRI or additional 4D Flow sequence
- Where
- France
- Volunteers
- 281 people
- Sponsor
- CHU de Reims
Alcohol Use Disorder
Self-Concept and Autobiographical Memory in Alcohol Use Disorder
This study has two objectives. First, to evaluate the effectiveness of psychotherapy sessions based on self-concept and autobiographical memory in patients suffering from alcohol use disorders (AUD).
- Trial name
- CoSMA (NCT06985927)
- Testing
- psychotherapeutic sessions
- Where
- France
- Volunteers
- 100 people
- Sponsor
- CHU de Reims
Periodontitis, Gingivitis
Intraoral Scanners as Periodontal and Dental Pathologies Diagnosis Tools
Periodontal diseases and dental pathologies are highly prevalent oral diseases. Thirty-three to fifty percent of adult population presented at least one untreated caries and more than 50% of French population are affected by…
- Conditions
- Periodontitis, Gingivitis, Dental Caries, Diagnosis
- Trial name
- Odonto3D (NCT06006429)
- Testing
- Numerical dental impression by intraoral scanner
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Shock, Right Ventricular Dysfunction
Right Ventriculo-Arterial Coupling During Fluid Loading in ICU Patients
Preload responsiveness and venous congestion have largely been investigated independently in recent literature. However, recent data report a similar incidence of venous congestion regardless of fluid responsiveness status…
- Conditions
- Shock, Right Ventricular Dysfunction, Venous Congestion
- Trial name
- RVPA-FLICU (NCT07537621)
- Testing
- Echography
- Where
- France
- Volunteers
- 100 people
- Sponsor
- CHU de Reims
Juvenile Idiopathic Arthritis
Sarcopenia and Juvenile Idiopathic Arthritis
Juvenile idiopathic arthritis (JIA) is a rare chronic inflammatory rheumatic disease that begins during childhood and may persist into adulthood in many patients.
- Trial name
- SAJI (NCT07634354)
- Testing
- Sarcopenia screening assessment
- Where
- France
- Volunteers
- 200 people
- Sponsor
- CHU de Reims
Alcohol Use Disorder
Social Cognition in Severe Alcohol Use Disorder
With 41,000 deaths per year, alcohol consumption is the second leading cause of preventable mortality in France. Nearly 3.4% of adults engage in excessive and chronic alcohol use, meeting criteria for Severe Alcohol Use Disorder…
- Trial name
- COSMO (NCT07464613)
- Testing
- Analysis of social functioning and social cognition processes
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Diabetic Retinopathy, Retinal Vein Occlusion
Soluble Cluster of Differentiation 160 (sCD160) in Sera and Intra-ocular Fluids: Association With Ischaemic Retinopathies
CD160 represents a new angiogenic factor as its specific engagement by an agonist monoclonal antibody directed against human CD160 reduced angiogenesis of endothelial cells with a distinct mechanism from current angiogenic…
- Trial name
- NCT03680794
- Testing
- sampling of ophthalmic liquid
- Where
- France
- Volunteers
- 120 people
- Sponsor
- CHU de Reims