DeathPOAFNCT02349269
Postoperative Atrial Fibrillation and Long-term Survival
An observational study of Death and Stroke, run by Kuopio University Hospital.
Trial summary
The aim of the investigators trial was to evaluate association between new onset postoperative atrial fibrillation (POAF) and late cardiovascular morbidity and mortality. Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Death, Stroke, Myocardial Infarction
- How many people
- 519 participants
- Where
- No sites listed yet
- Study dates
- Jan 2012to Sep 2014
- How long will I take part?
- 105 Months
- Phase
- Observational
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: patients without preoperative history of atrial fibrillation, participated in three different randomized controlled trials previously
Who may be able to join
- previously cardiac operation, CABG or AVR
Who cannot join
- Previous Atrial fibrillation
About this study
Official title: Postoperative Atrial Fibrillation After Cardiac Surgery is Not an Independent Risk Factor for Long-term Cardiovascular Morbidity and Mortality in Anticoagulated Patients
The aim of the investigators trial was to evaluate association between new onset postoperative atrial fibrillation (POAF) and late cardiovascular morbidity and mortality.
Read the detailed description
The material of this retrospective study consist patients without preoperative history of atrial fibrillation, participated in three different randomized controlled trials previously . A total of 519 consecutive patients underwent coronary artery bypass surgery, aortic valve replacement or combined aortic valve with coronary bypass surgery in Kuopio University Hospital from 2004 to 2008. Patients with previous episodes of atrial fibrillation (AF) or flutter and also patients with mitral valve surgery were excluded. All patients had continuous postoperative ECG monitoring for at least 48 hours. AF episodes lasting longer than 5 minutes were registered. Thereafter 12 lead ECG was recorded daily and in case of symptoms of rhythm disturbances.
Medical records were reviewed during 2012 using standardized data collection protocol. Statistics Finland database was used for mortality data.
- Conditions
- Death, Stroke, Myocardial Infarction
- Keywords
- Atrial fibrillation, CABG, Stroke
- Medical subject headings
- Death, Stroke, Myocardial Infarction, Atrial Fibrillation
What is being measured
The primary outcome is the main question the study is designed to answer.
cardiovascular and all-cause death
Measured: 1-105 month
stroke
Measured: 1-105 month
late atrial fibrillation
Measured: 1-105 month
myocardial infarction
Measured: 1-105 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Jan 2015 (estimated)
- Study startJan 2012
- Primary completionDec 2012
- Study completionSep 2014
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for DeathStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Enrolment
- 519 participants (actual)
- Target duration
- 105 Months
Sponsor and investigators
- Lead sponsor
- Kuopio University Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- University of Eastern Finland
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02349269
- Sponsor's protocol ID
- samuelm1
- Acronym
- POAF
- Status last verified
- Nov 2014
- First submitted
- 1 Dec 2014
- Last updated
- 28 Jan 2015
- Results posted
- No
- Data monitoring committee
- No