Fractures ReductionMEMOPROPONCT02200744
Incidence of Recall After Procedural Sedation With Propofol in the Emergency Department
An observational study of Fractures Reduction and Joint Dislocation Reduction, run by Centre Hospitalier Universitaire de la Réunion at 4 sites in France.
Trial summary
The purpose of this study is to determine the incidence of recall in patients managed in emergency department with a procedural sedation protocol using propofol in a population of 250 . Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Fractures Reduction, Joint Dislocation Reduction
- How many people
- 248 participants
- Where
- 4 sitesFrance
- Study dates
- 30 Jul 2014to 20 Sep 2018
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Adults patients managed in emergency department with a procedural sedation protocol using propofol
Who may be able to join
- Adults patients (> 18 years old) who had a procedural sedation in emergency department using propofol for fracture or joint dislocation reduction
- Patients who received an initial injection of Propofol by slow intravenous injection of 1 mg/kg in 20 seconds
- Inclusion less than 2 hours from the injection of Propofol
- Patients who have signed a consent to participate in the study
- Patients covered by social security.
Who cannot join
- Patients under 18 years old
- Patients who cannot signed the informed consent
- Patients who had procedural sedation using other drugs that propofol
- Participation in another study type biomedical research
Trial locations and contacts
4 sites in 1 country.
France4 sites
Groupe Hospitalier Est Réunion
Saint-Benoît, La Réunion, 97470
CHU de la Réunion
Saint-Denis, La Réunion, 97400
Centre Hospitalier Gabriel Martin
Saint-Paul, La Réunion, 97460
CHU de La Réunion
Saint-Pierre, La Réunion, 97448
About this study
The purpose of this study is to determine the incidence of recall in patients managed in emergency department with a procedural sedation protocol using propofol in a population of 250 .
Read the detailed description
After procedural sedation for fracture or joint dislocation reduction using propofol, adult patients recall will be assessed with a standardised form. This recall assessment will be realised 2 hours (+/- 15 minutes) after the procedural sedation and the day after.
The primary outcome measure will be the recall incidence 2 hours (+/- 15 minutes) after a procedural sedation. A secondary outcome will be the recall incidence one day after the procedural sedation.
The recall will be defined by a positive answer to the third question of the Sandin form (Lancet. 2000;355(9205):707-11).
- Conditions
- Fractures Reduction, Joint Dislocation Reduction
- Keywords
- Procedural sedation, emergency department, adults, propofol, recall assessment
- Medical subject headings
- Emergencies
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Dislocation reduction using propofol | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Recall incidence
questionnaire of Brice amended by Sandin
Measured: At 2 hours (+/- 15 minutes) after procedural sedation with propofol
Secondary outcomes (2)
Recall incidence
The patient will be contacted by phone the next day after procedural sedation with propofol. They will answer the questionnaire of Brice amended by Sandin
Measured: About 24 hours after procedural sedation with propofol
Patient's satisfaction assessment
numerical verbal scale
Measured: At 2 hours (+/- 15 minutes) after procedural sedation with propofol
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Jul 2014 (estimated)
- Study start30 Jul 2014
- Primary completion20 Sep 2018
- Study completion20 Sep 2018
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Fractures ReductionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 248 participants (actual)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Universitaire de la Réunion
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Pierre-Jean Marianne, MD, Principal investigator, CHU de La RéunionMarc Weber, MD, Principal investigator, Groupe Hospitalier Est RéunionKatia Mougin, MD, Principal investigator, Centre Hospitalier Gabriel Martin
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02200744
- Sponsor's protocol ID
- 2013/CHU/08
- Other IDs
- 2013-003669-32
- Acronym
- MEMOPROPO
- Status last verified
- Aug 2026
- First submitted
- 24 Jul 2014
- Last updated
- 6 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
Publications
Muller B, Mougin K, Weber M, Beti E, Guihard B, Tounkara BS, Combes X. Recall Incidence After Procedural Sedation With Propofol in Emergency Departments. J Emerg Med. 2025 Dec;79:457-462. doi: 10.1016/j.jemermed.2025.09.013. Epub 2025 Sep 9.
PubMed 41205307
Study at a glance
From the registry record, last updated by the sponsor on 6 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Incidence of Recall After Procedural Sedation With Propofol in the Emergency Department
- ClinicalTrials.gov ID
- NCT02200744
- Acronym / sponsor ID
- MEMOPROPO / 2013/CHU/08
- Conditions
- Fractures Reduction, Joint Dislocation Reduction
- Keywords
- Procedural sedation, emergency department, adults, propofol, recall assessment
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 248 participants (actual)
- Lead sponsor
- Centre Hospitalier Universitaire de la RéunionUniversity, hospital or other
- Study start
- 30 Jul 2014 (actual)
- Primary completion
- 20 Sep 2018 (actual)
- Study completion
- 20 Sep 2018 (actual)
- First posted
- 25 Jul 2014 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to determine the incidence of recall in patients managed in emergency department with a procedural sedation protocol using propofol in a population of 250 .
Detailed description
After procedural sedation for fracture or joint dislocation reduction using propofol, adult patients recall will be assessed with a standardised form. This recall assessment will be realised 2 hours (+/- 15 minutes) after the procedural sedation and the day after.
The primary outcome measure will be the recall incidence 2 hours (+/- 15 minutes) after a procedural sedation. A secondary outcome will be the recall incidence one day after the procedural sedation.
The recall will be defined by a positive answer to the third question of the Sandin form (Lancet. 2000;355(9205):707-11).
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Dislocation reduction using propofol | – | – |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Adults patients managed in emergency department with a procedural sedation protocol using propofol
Key inclusion criteria (5 listed)
- Adults patients (> 18 years old) who had a procedural sedation in emergency department using propofol for fracture or joint dislocation reduction
- Patients who received an initial injection of Propofol by slow intravenous injection of 1 mg/kg in 20 seconds
- Inclusion less than 2 hours from the injection of Propofol
- Patients who have signed a consent to participate in the study
- Patients covered by social security.
Key exclusion criteria (4 listed)
- Patients under 18 years old
- Patients who cannot signed the informed consent
- Patients who had procedural sedation using other drugs that propofol
- Participation in another study type biomedical research
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Recall incidence
Time frame: At 2 hours (+/- 15 minutes) after procedural sedation with propofol
questionnaire of Brice amended by Sandin
2 secondary outcomes
Recall incidence
Time frame: About 24 hours after procedural sedation with propofol
Patient's satisfaction assessment
Time frame: At 2 hours (+/- 15 minutes) after procedural sedation with propofol
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Aug 2026.
- Derived from this study: PubMed 41205307Muller B, Mougin K, Weber M, Beti E, Guihard B, Tounkara BS, Combes X. Recall Incidence After Procedural Sedation With Propofol in Emergency Departments. J Emerg Med. 2025 Dec;79:457-462. doi: 10.1016/j.jemermed.2025.09.013. Epub 2025 Sep 9.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Pierre-Jean Marianne, MD principal investigator
CHU de La Réunion
Marc Weber, MD principal investigator
Groupe Hospitalier Est Réunion
Katia Mougin, MD principal investigator
Centre Hospitalier Gabriel Martin
4 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Fractures Reduction and Joint Dislocation Reduction, run by Centre Hospitalier Universitaire de la Réunion at 4 sites in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 4 sites in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Recall incidence (time frame: At 2 hours (+/- 15 minutes) after procedural sedation with propofol). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT02200744, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Aug 2026.