Hematopoietic/Lymphoid CancerNCT01866969
Quality of Life in Caregivers of Hospitalized Older Patients With Cancer
A study testing questionnaire administration and quality-of-life assessment in people with Hematopoietic/Lymphoid Cancer and Unspecified Adult Solid Tumor, Protocol Specific, run by City of Hope Medical Center at 1 site in United States.
Trial summary
This clinical trial studies quality of life in caregivers of hospitalized older patients with cancer. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Hematopoietic/Lymphoid Cancer, Unspecified Adult Solid Tumor, Protocol Specific
- What is being tested?
- questionnaire administration and quality-of-life assessment
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 211 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Jul 2013to 1 May 2014
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- PATIENT: Age >= 65 years old
- PATIENT: Diagnosis of cancer (solid or hematologic malignancy)
- PATIENT: Be able to provide informed consent
- PATIENT: Unplanned admission to hospital
- CAREGIVER: Primary caregiver (person who provides all of the majority of the unpaid care for the care recipient)
- CAREGIVER: Be able to provide informed consent
Who cannot join
- PATIENT: Planned admission to hospital for treatment (chemotherapy, transplant)
- CAREGIVER: Not fluent in English (because not all questionnaires have been validated in other languages)
- CAREGIVER: Paid and trained to care for the patient
Trial locations and contacts
1 site in 1 country.
United States1 site
City of Hope Medical Center
Duarte, California, 91010
About this study
Official title: Physical, Emotional and Social Stressors and Their Impact on Quality of Life of Caregivers of Hospitalized Older Adults With Cancer
This clinical trial studies quality of life in caregivers of hospitalized older patients with cancer.
Read the detailed description
PRIMARY OBJECTIVES:
- Identify patient and caregiver factors associated with increased caregiver burden and decreased quality of life in caregivers of older adults with cancer.
SECONDARY OBJECTIVES:
- Determine characteristics of informal caregivers of older adults with cancer admitted to hospital.
II. Determine type and amount of care informal caregivers provide for older adults with cancer admitted to hospital.
III. Determine quality of life in informal caregivers of older adults with cancer admitted to hospital.
IV. Identify caregiver needs, both informational and resource related. V. Explore the association between re-admission to the hospital within 30 days and caregiver burden.
VI. Explore whether feedback of information attained from the assessment of the caregiver influences services implemented by the health care team.
VII. Determine reasons for non-participation.
OUTLINE:
Caregivers complete a questionnaire about their sociodemographics, physical health, social supports, social activity, mental health and caregiver burden. They will also provide an assessment of the person they care for.
- Being tested
- questionnaire administration, quality-of-life assessment
- Medical subject headings
- Hematologic Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
questionnaire administrationOther
Ancillary studies
quality-of-life assessmentProcedure or surgery
Also called quality of life assessment
Ancillary studies
| Study group | Role | What they receive |
|---|---|---|
| Supportive care (quality of life questionnaire) | Experimental | Caregivers complete a self-administered questionnaire about factors associated with increased caregiver burden and decreased quality of life. Receives: Other: questionnaire administration; Procedure: quality-of-life assessment |
What is being measured
The primary outcome is the main question the study is designed to answer.
Caregiver burden and caregiver quality of life as measured by the Caregiver Quality of Life-Cancer Index
Univariate analyses will be performed to test differences in the Caregiver Quality of Life-Cancer Index (CQOLC) total score and score of each domain (burden, distinctiveness, positive adaption, and financial concern) across categorical variables (analysis of variance [ANOVA]), and simple linear regression will be used to test association of CQOLC total score with continuous and categorical variables.
Measured: Up to 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Jun 2013 (estimated)
- Study start1 Jul 2013
- Primary completion1 May 2014
- Study completion1 May 2014
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hematopoietic/Lymphoid CancerStudies of the same condition, open and under way.
- More trials run by City of Hope Medical CenterThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 211 participants (actual)
Sponsor and investigators
- Lead sponsor
- City of Hope Medical Center
- Sponsor type
- University, hospital or other
- Collaborators
- National Cancer Institute (NCI)
- Responsible party
- Sponsor
- Investigators
- Arti Hurria, MD, Principal investigator, City of Hope Medical Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01866969
- Sponsor's protocol ID
- 13158
- Other IDs
- NCI-2013-01068, 13158
- Status last verified
- Oct 2026
- First submitted
- 29 May 2013
- Last updated
- 19 Oct 2026
- Results posted
- No
- Data monitoring committee
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 19 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Physical, Emotional and Social Stressors and Their Impact on Quality of Life of Caregivers of Hospitalized Older Adults With Cancer
- ClinicalTrials.gov ID
- NCT01866969
- Acronym / sponsor ID
- 13158
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 211 participants (actual)
- Lead sponsor
- City of Hope Medical CenterUniversity, hospital or other
- Collaborators
- National Cancer Institute (NCI)
- Study start
- 1 Jul 2013 (actual)
- Primary completion
- 1 May 2014 (actual)
- Study completion
- 1 May 2014 (actual)
- First posted
- 3 Jun 2013 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This clinical trial studies quality of life in caregivers of hospitalized older patients with cancer.
Detailed description
PRIMARY OBJECTIVES:
- Identify patient and caregiver factors associated with increased caregiver burden and decreased quality of life in caregivers of older adults with cancer.
SECONDARY OBJECTIVES:
- Determine characteristics of informal caregivers of older adults with cancer admitted to hospital.
II. Determine type and amount of care informal caregivers provide for older adults with cancer admitted to hospital.
III. Determine quality of life in informal caregivers of older adults with cancer admitted to hospital.
IV. Identify caregiver needs, both informational and resource related. V. Explore the association between re-admission to the hospital within 30 days and caregiver burden.
VI. Explore whether feedback of information attained from the assessment of the caregiver influences services implemented by the health care team.
VII. Determine reasons for non-participation.
OUTLINE:
Caregivers complete a questionnaire about their sociodemographics, physical health, social supports, social activity, mental health and caregiver burden. They will also provide an assessment of the person they care for.
Study design
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Supportive care (quality of life questionnaire) | Experimental | Other: questionnaire administration, Procedure: quality-of-life assessmentCaregivers complete a self-administered questionnaire about factors associated with increased caregiver burden and decreased quality of life. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- PATIENT: Age >= 65 years old
- PATIENT: Diagnosis of cancer (solid or hematologic malignancy)
- PATIENT: Be able to provide informed consent
- PATIENT: Unplanned admission to hospital
- CAREGIVER: Primary caregiver (person who provides all of the majority of the unpaid care for the care recipient)
Key exclusion criteria (3 listed)
- PATIENT: Planned admission to hospital for treatment (chemotherapy, transplant)
- CAREGIVER: Not fluent in English (because not all questionnaires have been validated in other languages)
- CAREGIVER: Paid and trained to care for the patient
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| questionnaire administrationAncillary studies | Other | Supportive care (quality of life questionnaire) |
| quality-of-life assessmentAlso: quality of life assessmentAncillary studies | Procedure or surgery | Supportive care (quality of life questionnaire) |
Primary outcome
Caregiver burden and caregiver quality of life as measured by the Caregiver Quality of Life-Cancer Index
Time frame: Up to 1 year
Univariate analyses will be performed to test differences in the Caregiver Quality of Life-Cancer Index (CQOLC) total score and score of each domain (burden, distinctiveness, positive adaption, and financial concern) across categorical variables (analysis of variance [ANOVA]), and simple linear regression will be used to test association of CQOLC total score with continuous and categorical variables.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Oct 2026.
Related trials for Hematopoietic/Lymphoid Cancer
Active, not recruitingPhase 2
Testing AZD5363 as a Potential Targeted Treatment in Cancers With AKT Genetic Changes (MATCH-Subprotocol Y)
Advanced Lymphoma, Advanced Malignant Solid Neoplasm
Active, not recruitingPhase 1
Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers
Bladder Carcinoma, Cervical Carcinoma
Active, not recruitingPhase 2
Testing GDC-0032 (Taselisib) as a Potential Targeted Treatment in Cancers With PIK3CA Genetic Changes (MATCH-Subprotocol I)
Advanced Lymphoma, Advanced Malignant Solid Neoplasm
RecruitingPhase 2
At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
Advanced Anal Carcinoma, Advanced Biliary Tract Carcinoma
RecruitingObservational study
Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers, CHANCES Study
Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Arti Hurria, MD principal investigator
City of Hope Medical Center
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing questionnaire administration and quality-of-life assessment in people with Hematopoietic/Lymphoid Cancer and Unspecified Adult Solid Tumor, Protocol Specific, run by City of Hope Medical Center at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Caregiver burden and caregiver quality of life as measured by the Caregiver Quality of Life-Cancer Index (time frame: Up to 1 year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Oct 2026.