UveitisATACNCT01746537
Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography
An observational study of Uveitis, run by The Cleveland Clinic at 1 site in United States.
Trial summary
A prospective, observational, case series investigating the feasibility of utilizing OCT scans of the anterior chamber of eyes with uveitis. Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Uveitis
- How many people
- 1,500 participants
- Where
- 1 siteUnited States
- Study dates
- Jun 2012to Jun 2029
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: Patients with inactive and active uveitis.
Who may be able to join
- All patients presenting to Cole Eye Institute with uveitis.
Who cannot join
- Inability to provide informed consent, including non-English speaking and cognitively/mentally impaired.
- Severe corneal opacities preventing imaging of anterior chamber
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Sunil K Srivastava, M.D. contact
Kimberly M Baynes, BSN, RN contact
United States1 site, 1 recruiting
- Recruiting
Cole Eye Institute
Cleveland, Ohio, 44195
Sunil K Srivastava, M.D., 216-636-2286
Kimberly M Baynes, BSN,RN, 216-444-2566
About this study
Official title: Automated Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography
A prospective, observational, case series investigating the feasibility of utilizing OCT scans of the anterior chamber of eyes with uveitis.
- Conditions
- Uveitis
- Medical subject headings
- Uveitis
What is being measured
The primary outcome is the main question the study is designed to answer.
Use the OCT to objectively image and grade the degree of anterior chamber inflammation in eyes with inactive and active uveitis.
Measured: one year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Dec 2012 (estimated)
- Study startJun 2012
- Primary completionJun 2028 (estimated)
- Study completionJun 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for UveitisStudies of the same condition, open and under way.
- More trials run by The Cleveland ClinicThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 1,500 participants (estimated)
Sponsor and investigators
- Lead sponsor
- The Cleveland Clinic
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Sunil Srivastava, The Cleveland Clinic
- Investigators
- Sunil K Srivastva, MD, Principal investigator, The Cleveland Clinic
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01746537
- Sponsor's protocol ID
- 12-612
- Acronym
- ATAC
- Status last verified
- Mar 2026
- First submitted
- 7 Dec 2012
- Last updated
- 4 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
Study at a glance
From the registry record, last updated by the sponsor on 4 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Automated Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography
- ClinicalTrials.gov ID
- NCT01746537
- Acronym / sponsor ID
- ATAC / 12-612
- Conditions
- Uveitis
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 1,500 participants (estimated)
- Lead sponsor
- The Cleveland ClinicUniversity, hospital or other
- Study start
- Jun 2012
- Primary completion
- Jun 2028 (estimated)
- Study completion
- Jun 2029 (estimated)
- First posted
- 11 Dec 2012 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
A prospective, observational, case series investigating the feasibility of utilizing OCT scans of the anterior chamber of eyes with uveitis.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Patients with inactive and active uveitis.
Key inclusion criteria (1 listed)
- All patients presenting to Cole Eye Institute with uveitis.
Key exclusion criteria (2 listed)
- Inability to provide informed consent, including non-English speaking and cognitively/mentally impaired.
- Severe corneal opacities preventing imaging of anterior chamber
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Use the OCT to objectively image and grade the degree of anterior chamber inflammation in eyes with inactive and active uveitis.
Time frame: one year
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Mar 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Sunil K Srivastava, M.D. contact
Kimberly M Baynes, BSN, RN contact
Sunil K Srivastva, MD principal investigator
The Cleveland Clinic
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Uveitis, run by The Cleveland Clinic at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 4 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Sunil K Srivastava, M.D. (216-636-2286), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Use the OCT to objectively image and grade the degree of anterior chamber inflammation in eyes with inactive and active uveitis. (time frame: one year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Mar 2026.