AzTrials
AzTrials

StrokeNCT01468701

GLORIA-AF Registry Program - Second and Third Phases

An observational study of Stroke and Atrial Fibrillation, run by Boehringer Ingelheim at 666 sites in 21 countries.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
Search all trials

Trial summary

In this part of the Registry Program patients with non-valvular atrial fibrillation (AF) at risk for stroke are enrolled to characterize the target population and to collect real world data on important outcome events. Read more about this study

Who is it for?
Ages 18 years and older
Conditions the study is for
Stroke, Atrial Fibrillation
How many people
37,235 participants
Where
666 sitesin 21 countries
Study dates
7 Nov 2011to 10 Jan 2020
Phase
Observational
Are there results?
Yes, posted in the registrySummary in the doctors' view

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Study population: patients with non-valvular AF

Who may be able to join

  • Age =>18 years at enrollment
  • Male or female patient (or legally acceptable representative) willing and able to provide written informed consent
  • Patient newly diagnosed (< 3 months prior to baseline visit) with non-valvular AF and at risk for stroke.
  • Other inclusion criteria apply.

Who cannot join

  • Presence of any mechanical heart valve, or valve disease that is expected to require valve replacement intervention;
  • Patients who have received more than 60 days of vitamin K antagonist (VKA) treatment in their lifetime;
  • AF with a generally reversible cause;
  • Patients with a medical condition other than atrial fibrillation for which chronic use of an oral anticoagulant (for example, a VKA) is indicated Other exclusion criteria apply

Trial locations and contacts

666 sites in 21 countries.

642 sites in 21 countries

United States300 sites
  • Abington Medical Specialists

    Abington, Pennsylvania, 19003

  • Albany Medical Center / Albany Medical College

    Albany, New York, 12208

  • Lovelace Scientific Resources, Inc.

    Albuquerque, New Mexico, 87108

  • Cambridge Medical Trials

    Alexandria, Louisiana, 71301

  • Endeavor Medical Research

    Alpena, Michigan, 49707

  • McFarland Clinic PC

    Ames, Iowa, 50010

  • Alaska Heart Institute

    Anchorage, Alaska, 99508

  • AnMed Health Clinical Research

    Anderson, South Carolina, 29621

  • Internal Medicine Associates of Anderson, PA

    Anderson, South Carolina, 29621

  • Cardiac Consultants, LLC

    Annapolis, Maryland, 21401

  • Northwest Heart Clinical Research, LLC

    Arlington Heights, Illinois, 60005

  • Executive Health and Research Associates

    Atlanta, Georgia, 30342

  • Saint Joseph's Research Institute

    Atlanta, Georgia, 30342

  • Aurora Denver Cardiology Associates, PC

    Aurora, Colorado, 80012

  • THV Research, LLC

    Austin, Texas, 78745

  • Aventura Institute for Cardiovascular Wellness, PA

    Aventura, Florida, 33180

  • Primary Care Cardiology Research, Inc

    Ayer, Massachusetts, 01432

  • MedStar Health Research Institute

    Baltimore, Maryland, 21218

  • Cardiovascular Research Foundation of Louisiana

    Baton Rouge, Louisiana, 70808

  • McLaren Bay Region Medical Center

    Bay City, Michigan, 48708

  • Lowcountry Medical Group, LLC

    Beaufort, South Carolina, 29906

  • Southeast Texas Clinical Research Center

    Beaumont, Texas, 77702

  • Southern Maine Health Care

    Biddeford, Maine, 04005

  • The Center for Clinical Trials, Inc.

    Biloxi, Mississippi, 39531

  • Grace Research, LLC

    Bossier City, Louisiana, 71111

  • Bay Area Cardiology

    Brandon, Florida, 33511

  • Connecticut Clinical Research, LLC

    Bridgeport, Connecticut, 06606

  • Connecticut Heart and Vascular Center

    Bridgeport, Connecticut, 06606

  • Bridgeport Hospital

    Bridgeport, Connecticut, 06610

  • Medicor Cardiology

    Bridgewater, New Jersey, 08807

  • Genesys Research Institute, Incorporated

    Brighton, Massachusetts, 02135

  • New York -Presbyterian Brooklyn Methodist Hospital

    Brooklyn, New York, 11215

  • Hendricks Family Medicine

    Brownsburg, Indiana, 46112

  • Burke Internal Medicine and Research

    Burke, Virginia, 22015

  • Kernodle Clinic West

    Burlington, North Carolina, 27215

  • Cooper University Hospital

    Camden, New Jersey, 08014

  • Community Cardiology

    Camillus, New York, 13031

  • Capital Area Research, LLC

    Camp Hill, Pennsylvania, 17011

  • Aultman Hospital

    Canton, Ohio, 44710

  • Prairie Cardiovascular Memorial Hospital

    Carbondale, Illinois, 62901

  • Preferred Primary Care Phys

    Carnegie, Pennsylvania, 15106

  • Chambersburg Hospital

    Chambersburg, Pennsylvania, 17201

  • CAMC Clinical Trials Center

    Charleston, West Virginia, 25304

  • University of Virginia Health System

    Charlottesville, Virginia, 22908

  • Office of Yvonne Chester

    Chattanooga, Tennessee, 37404

  • Cardiovascular Associates, Ltd

    Chesapeake, Virginia, 23320

  • Captain James A. Lovell Federal Health Care Center

    Chicago, Illinois, 60064

  • Medex Healthcare Research

    Chicago, Illinois, 60602

  • John H. Stroger Jr. Hospital of Cook Country

    Chicago, Illinois, 60612

  • University of Illinois at Chicago

    Chicago, Illinois, 60612

  • North Shore Cardiology Consultants

    Chicago, Illinois, 60631

  • University of Chicago

    Chicago, Illinois, 60637

  • University of Cincinnati

    Cincinnati, Ohio, 45267

  • Tampa Bay Medical Research

    Clearwater, Florida, 33761

  • The MetroHealth System

    Cleveland, Ohio, 44109-1998

  • MedStar Southern Maryland Hospital Center

    Clinton, Maryland, 20735

  • Kootenai Heart Clinics, LLC

    Coeur d'Alene, Idaho, 83814

  • Lynn Institute of the Rockies

    Colorado Springs, Colorado, 80909

  • Pikes Peak Cardiology

    Colorado Springs, Colorado, 80909

  • Cardiovascular Specialists of Central Maryland

    Columbia, Maryland, 21044

  • South Carolina Heart Center

    Columbia, South Carolina, 29204

  • Bassett Medical Center

    Cooperstown, New York, 13326

  • Good Samaritan Hospital Corvallis

    Corvallis, Oregon, 97330

  • Atlanta Heart Specialists, LLC

    Cumming, Georgia, 30041

  • Dallas VA Medical Center

    Dallas, Texas, 75216

  • Heartplace

    Dallas, Texas, 75226

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390-8837

  • Cardiology Consultants of Danville, Inc

    Danville, Virginia, 24541

  • William C McGarity, Jr, MD, PC

    Decatur, Georgia, 30035

  • Seidman Clinical Trials

    Delray Beach, Florida, 33484

  • Denver Health Medical Center

    Denver, Colorado, 80204

  • Henry Ford Hospital K-15

    Detroit, Michigan, 48202

  • Universal Clinical Research Associates

    Doral, Florida, 33166

  • Central Bucks Cardiology

    Doylestown, Pennsylvania, 18901

  • Essentia Heart and Vascular Clinic

    Duluth, Minnesota, 55805

  • Monmouth Cardiology Associates

    Eatontown, New Jersey, 07724

  • Central Cardiology Associates

    Elizabethtown, Kentucky, 42701

  • Diagnamics, Inc

    Encinitas, California, 92024

  • Physician Specialist of Northern Lancaster County Medcl Grp

    Ephrata, Pennsylvania, 17522

  • St. Vincent Consultants in Cardiovascular Disease, LLC

    Erie, Michigan, 16502

  • Northwestern University

    Evanston, Illinois, 60208

  • Mercy Health Fairfield Hospital

    Fairfield, Ohio, 45014

  • Advanced Heart Care, LLC, Medicoricum, LLC

    Fairview Heights, Illinois, 62208

  • Cleveland Cardiovascular Research Foundation

    Fairview Park, Ohio, 44126

  • NECCR Internal Med and Cardio

    Fall River, Massachusetts, 02720

  • Inova Research Center

    Falls Church, Virginia, 22042

  • Virginia Heart

    Falls Church, Virginia, 22042

  • Lillestol Research, LLC

    Fargo, North Dakota, 58103

  • Cardiology Consultants of East Michigan

    Flint, Michigan, 48532

  • New York Hospital Queens

    Flushing, New York, 11355

  • Sparks Regional Medical Center

    Fort Smith, Arkansas, 72901

  • Parkview Research Center

    Fort Wayne, Indiana, 46845

  • Amir Malik Research

    Fort Worth, Texas, 76104

  • Allianz Medical and Research Center

    Fountain Valley, California, 92708

  • Mary Washington Hospital Research Department

    Fredericksburg, Virginia, 22401

  • B&K Medical Research Center

    Fresno, California, 93721

  • Cardiovascular Research of North Florida LLC

    Gainesville, Florida, 32605

  • Phoenix Heart PLLC

    Glendale, Arizona, 85306

  • Genesys Heart Institute

    Grand Blanc, Michigan, 48439

  • Regional Cardiology Associates

    Grand Blanc, Michigan, 48439

  • State of the Heart Cardiology

    Grapevine, Texas, 76051

  • Piedmont Cardiology Associates, P.A.

    Greenwood, South Carolina, 29646

  • Electrophysiology Associates of Northern New Jersey

    Hackensack, New Jersey, 07601

  • Advocare Heights Primary Care

    Haddon Heights, New Jersey, 08035

  • Heart Clinic of Hammond

    Hammond, Louisiana, 70403

  • Associated Cardiovascular Consultants Lourdes

    Hammonton, New Jersey, 08037

  • Harleysville Medical Associates

    Harleysville, Pennsylvania, 19438

  • Harrisonburg Medical Associates

    Harrisonburg, Virginia, 22801

  • American Clinical Trials

    Hawaiian Gardens, California, 90716

  • Magi Research Clinic, Inc

    Hialeah, Florida, 33013

  • Clinical Trials of America, Inc

    Hickory, North Carolina, 28601

  • Carolina Cardiology Cornerstone

    High Point, North Carolina, 27262

  • Adventist Health Partners, Inc

    Hinsdale, Illinois, 60521

  • Global Research Solutions Corporation

    Hollywood, Florida, 33021

  • Mercy Cinic Hot Springs Communities

    Hot Springs, Arizona, 71913

  • Dr. Michael A. Frais, Cardiologist, P.A.

    Hot Springs, Arkansas, 71913

  • Angiocardiac Care of Texas

    Houston, Texas, 77025

  • Houston Methodist DeBakey Cardiology Associates

    Houston, Texas, 77030

  • Barry Troyan, M.D, PA

    Houston, Texas, 77043

  • Centex Studies, Inc.

    Houston, Texas, 77062

  • Dairy Ashford Family Pratice

    Houston, Texas, 77077

  • Emil Hayek, M.D., Inc

    Hudson, Ohio, 44236

  • Cardiovascular Associates PLLC

    Humble, Texas, 77338

  • University Cardiovascular Services

    Huntington, West Virginia, 25701

  • St. Mary's Medical Center

    Huntington, West Virginia, 25702

  • St. Vincent Medical Group

    Indianapolis, Indiana, 46260

  • University of Iowa Hospitals and Clinics

    Iowa City, Iowa, 52242

  • University Of Mississippi Medical Center

    Jackson, Mississippi, 39216

  • The Jackson Clinic, PA

    Jackson, Tennessee, 38301

  • St. Vincent's Ambulatory Care

    Jacksonville, Florida, 32216

  • Profen Research Network at East Carolina Medical Associates

    Jacksonville, North Carolina, 28546

  • Lycoming Internal Medicine, Inc

    Jersey Shore, Pennsylvania, 17740

  • UHS Office of Clinical Trials

    Johnson City, New York, 13790

  • Center For Cardiovascular Research

    Johnson City, Tennessee, 37604

  • Tenet Florida Physician Services

    Jupiter, Florida, 33458

  • Kalispell Regional Medical Center

    Kalispell, Montana, 59901

  • Kannapolis Internal Medicine

    Kannapolis, North Carolina, 28083

  • Health Midwest Ventures Group, Inc

    Kansas City, Missouri, 64132

  • Cardiology Center of Houston, PA

    Katy, Texas, 77450

  • Innovation Center, Kettering Medical Center

    Kettering, Ohio, 45429

  • Texas Cardiology Research Center PLLC

    Kingwood, Texas, 77339

  • PMG Research of Knoxville

    Knoxville, Tennessee, 37912

  • Tennova Healthcare-Turkey Creek Medical Center

    Knoxville, Tennessee, 37934

  • PMG Research of Knoxville

    Knoxville, Tennessee, 37938

  • Mayo Clinic-Sparta

    La Crosse, Wisconsin, 54601

  • Scripps Clinic

    La Jolla, California, 92037

  • La Mesa Cardiac Center

    La Mesa, California, 91942

  • Beacon Medical Group Clinical Research

    La Porte, Indiana, 46350

  • Cardiovascular Specialists of Southwest Louisiana, LLC

    Lake Charles, Louisiana, 70601

  • Midwest Internal Medicine, PLLC

    Lake Havasu City, Arizona, 86403

  • Watson Clinic Center for Research, Inc

    Lakeland, Florida, 33805

  • Cardiology Consultants of Philadelphia

    Lansdale, Pennsylvania, 19446-3748

  • Thoracic and Cardiovascular Healthcare Foundation

    Lansing, Michigan, 48910

  • Clinical Trials of America, Inc

    Lenoir, North Carolina, 28645

  • NJ Heart LLC

    Linden, New Jersey, 07036

  • Cardiology and Medicine Clinic

    Little Rock, Arkansas, 72204

  • Donald W. Reynolds Institute on Aging

    Little Rock, Arkansas, 72205-7199

  • Arkansas Cardiology, PA

    Little Rock, Arkansas, 72205

  • South Denver Cardiology Associates, PC

    Littleton, Colorado, 80120

  • Los Alamitos Cardiovascular

    Los Alamitos, California, 90720

  • VA Greater Los Angeles Healthcare System

    Los Angeles, California, 90073

  • Robley Rex VA Medical Center

    Louisville, Kentucky, 40206

  • Caprock Cardiac Center Research Institute

    Lubbock, Texas, 79410

  • Coliseum Medical Center

    Macon, Georgia, 31217

  • Baptist Health Clinical Studies

    Madisonville, Kentucky, 42431

  • Garden State Heart Care, PC

    Manalapan, New Jersey, 07726

  • Manassas Clinical Research Center

    Manassas, Virginia, 20110

  • RAS Health Ltd

    Marion, Ohio, 43302

  • Frederick C Smith Clinic Inc

    Marion, Ohio, 43342

  • Upper Michigan Cardiovascular Associates, PC

    Marquette, Michigan, 49855

  • Consultants in Cardiovascular Medicine

    Melrose Park, Illinois, 60160

  • Medpharmics, LLC

    Metairie, Louisiana, 70006

  • A&L Clinical Research

    Miami, Florida, 33126

  • Miami Center for Cardiovascular Disease

    Miami, Florida, 33136

  • Global Research Solutions Corporation

    Miami, Florida, 33144

  • Cardiovascular Research Center of South Florida

    Miami, Florida, 33173

  • New Horizon Research Center

    Miami, Florida, 33175

  • Mound Family Practice

    Miamisburg, Ohio, 45342

  • Cardiovascular Associates of Virginia

    Midlothian, Virginia, 23114

  • Karim Bakhtiar MD, SC

    Milwaukee, Wisconsin, 53215

  • Family Medical Clinic

    Milwaukee, Wisconsin, 53216

  • Wheaton Franciscan

    Milwaukee, Wisconsin, 53221

  • Milwaukee VA Medical Center

    Milwaukee, Wisconsin, 53295

  • Long Island Heart Associates

    Mineola, New York, 11501

  • Minneapolis Heart Institute Foundation

    Minneapolis, Minnesota, 55407

  • Trinity Health Center Medical Arts

    Minot, North Dakota, 58701

  • Sacred Heart Medical Specialty Group

    Miramar Beach, Florida, 32550

  • University South Alabama Medical Center

    Mobile, Alabama, 38817

  • Koch Family Medicine

    Morton, Illinois, 61550

  • McLaren-Macomb

    Mount Clemens, Michigan, 48043

  • Office of Dr. Paul McLaughlin, M.D.

    Mount Sterling, Kentucky, 40353

  • Cardiology Associates of Northwest Indiana, PC

    Munster, Indiana, 46321

  • Family Medicine of SayeBrook

    Myrtle Beach, South Carolina, 29588

  • Collier HMA Physician Management

    Naples, Florida, 34119

  • Atlantic Cardiology, LLC

    Neptune City, New Jersey, 07753

  • Mission Research Institute, LLC

    New Braunfels, Texas, 78130

  • Rutgers Robert Wood Johnson Medical School

    New Brunswick, New Jersey, 08901

  • LSU Health Sciences Center

    New Orleans, Louisiana, 70112

  • Edgewater Medical Research

    New Smyrna Beach, Florida, 32169

  • Chinatown Cardiology, PC

    New York, New York, 10013

  • Lenox Hill Hospital

    New York, New York, 10021

  • Saint Luke - Roosevelt Hospital Center

    New York, New York, 10025

  • Red Clay Research LLC.

    Newark, Delaware, 19713

  • Newton-Wellesley Hospital

    Newton, Massachusetts, 02462

  • South Western Medical Clinic

    Niles, Michigan, 49120

  • Black Warrior Research

    Northport, Alabama, 35476

  • Mehrdad Kevin Ariani, MD, Incorporated

    Northridge, California, 91325

  • Cardiology Associates of Fairfield County

    Norwalk, Connecticut, 06851

  • Norwalk Medical Group

    Norwalk, Connecticut, 06851

  • Providence Park Hospital

    Novi, Michigan, 48374

  • SouthEast Medical Centre

    Oakland Park, Florida, 33309

  • Oklahoma Foundation for Cardiovascular Research

    Oklahoma City, Oklahoma, 73120

  • MidAmerica Cardiovascular Institute

    Omaha, Nebraska, 68131

  • Meridian Clinical Research, LLC

    Omaha, Nebraska, 68134

  • Board of Regents of the University of Nebraska

    Omaha, Nebraska, 68198-7835

  • Research One

    Orlando, Florida, 32806

  • Midwest Heart and Vascular Specialists

    Overland Park, Kansas, 66211

  • Research Integrity, LLC

    Owensboro, Kentucky, 42303

  • VA Palo Alto Health Care System

    Palo Alto, California, 94304

  • Alegent Health Heart and Vascular Specialists

    Papillion, Nebraska, 68046

  • Saint Joseph's Regional Medical Center

    Paterson, New Jersey, 07503

  • Memorial Hospital of RI

    Pawtucket, Rhode Island, 02860

  • South Florida Research Solutions, LLC

    Pembroke Pines, Florida, 33028

  • Langhorne Cardiology Consultants, Inc

    Pensacola, Florida, 32501

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104-6205

  • Pennsylvania Cardiology Associates

    Philadelphia, Pennsylvania, 19106

  • Einstein Medical Center Philadelphia

    Philadelphia, Pennsylvania, 19141

  • Pinehurst Medical Clinic, Inc

    Pinehurst, North Carolina, 28374

  • Allegheny Neurology Associates

    Pittsburgh, Pennsylvania, 15212

  • VNH Heart Center Research

    Port Charlotte, Florida, 33952

  • Sound Medical Research

    Port Orchard, Washington, 98366

  • Fanno Creek Clinic, LLC

    Portland, Oregon, 97219

  • Wake Heart Research

    Raleigh, North Carolina, 27610

  • Eisenhower Desert Cardiology Center

    Rancho Mirage, California, 92270

  • Black Hills Cardiovascular Research

    Rapid City, South Dakota, 57701

  • Renown Institute for Heart and Vascular Health

    Reno, Nevada, 89502

  • VA Sierra Nevada Health Care System

    Reno, Nevada, 89502

  • CJW Medical Center - Chippenham

    Richmond, Virginia, 23225

  • The Valley Hospital

    Ridgewood, New Jersey, 07450

  • Carilion Clinic

    Roanoke, Virginia, 24014

  • Advanced Cardiovascular Consultants

    Rock Island, Illinois, 61201

  • Brevard Cardiovascular Research Associates, Inc

    Rockledge, Florida, 32955

  • Covenant Medical Center, Inc.

    Saginaw, Michigan, 48602

  • MId-MIchigan Heart and Vascular Center

    Saginaw, Michigan, 48604

  • CentraCare Heart and Vascular Center

    Saint Cloud, Minnesota, 56303

  • Heartland Regional Medical Center

    Saint Joseph, Missouri, 64506

  • United Heart and Vascular Clinic

    Saint Paul, Minnesota, 55102

  • Salem VA Medical Center

    Salem, Virginia, 24153

  • Delmarva Heart Research Foundation, Inc

    Salisbury, Maryland, 21804

  • Peninsula Cardiology Associates

    Salisbury, Maryland, 21804

  • Heart Center at Saint Mark's

    Salt Lake City, Utah, 84124

  • Highland Clinical Research

    Salt Lake City, Utah, 84124

  • Mercury Medical ,LLC

    San Antonio, Texas, 78229

  • Texas Medical Research Associates

    San Antonio, Texas, 78238

  • Ritchken and First MD's

    San Diego, California, 92117

  • Coastal Heart Group Inc

    Santa Ana, California, 92704

  • Velella Research, Inc

    Sarasota, Florida, 34233

  • Cardiovascular Center of Sarasota

    Sarasota, Florida, 34239

  • Saratoga Clinical Research, LLC

    Saratoga Springs, New York, 12866

  • Scottsboro Quick Care Clinic

    Scottsboro, Alabama, 35768

  • Sealy Urgent Care Center and Medical Clinic

    Sealy, Texas, 77474

  • The Polyclinic

    Seattle, Washington, 98133

  • Seguin Institute of Cardiovascular Research

    Seguin, Texas, 78155

  • Grand View - Lehigh Valley Health Services

    Sellersville, Pennsylvania, 18960

  • James C. Neiman, MD

    Seminole, Florida, 33772

  • Heart Specialists, PC of Southern CT

    Shelton, Connecticut, 06484

  • Advanced Cardiovascular Specialists

    Shreveport, Louisiana, 71103

  • Louisiana Heart Center

    Slidell, Louisiana, 70458

  • Heart and Vascular Center of New Brunswick

    Somerset, New Jersey, 08873

  • Beacon Medical Group Clinical Research

    South Bend, Indiana, 46601

  • Central New Jersey Cardiology

    South Plainfield, New Jersey, 07080

  • Heart House Research Foundation, LLC

    Springfield, Ohio, 45504

  • Sacred Heart Medical Center at RiverBend

    Springfield, Oregon, 97477

  • Saint Louis University

    St Louis, Missouri, 63110

  • Consult and Research Associates

    St Louis, Missouri, 63122

  • Gateway Cardiology, PC

    St Louis, Missouri, 63128

  • Suncoast Cardiovascular Research Inc.

    St. Petersburg, Florida, 33701

  • Northside Hospital

    St. Petersburg, Florida, 33709

  • Alternative Solutions Medical Research and Prevention Center

    St. Petersburg, Florida, 33711

  • Pacific Heart and Vascular

    Stockton, California, 95210

  • Stony Brook Cardiology/Electrophysiology

    Stony Brook, New York, 11794-8167

  • Sugarland Cardiology

    Sugar Land, Texas, 77479

  • SUNY Upstate Medical University

    Syracuse, New York, 13202

  • New York Heart Center

    Syracuse, New York, 13210

  • Franciscan Heart and Vascular Associates

    Tacoma, Washington, 98405

  • Tallahassee Research Instutite

    Tallahassee, Florida, 32308

  • University of South Florida

    Tampa, Florida, 33606

  • Southwest Heart Institute

    Temecula, California, 92591

  • Cardiac Care and Vascular Medicine, PLLC

    The Bronx, New York, 10469

  • Cardiovascular Research Center

    Toledo, Ohio, 43608

  • Toledo Clinic Incorporated

    Toledo, Ohio, 43623

  • University of California Los Angeles

    Torrance, California, 90509

  • Chesapeake Cardiovascular Associates

    Towson, Maryland, 21204

  • Cardiovascular Associates of East Texas, PA

    Tyler, Texas, 75701

  • Trinity Clinic

    Tyler, Texas, 75702

  • University of Texas Health Science Center at Tyler

    Tyler, Texas, 75708

  • Cardiology Associates Medical Group Inc

    Ventura, California, 93003

  • Ventura Cardiology Consultants Medical Group, Inc

    Ventura, California, 93003

  • Ventura Clinical Trials

    Ventura, California, 93003

  • Indian River Medical Associates Cardiology

    Vero Beach, Florida, 32960

Other trials in United States

China59 sites
  • Beijing AnZhen Hospital

    Beijing, 100029

  • Peking University First Hospital

    Beijing, 100034

  • Cardiovascular Institute and Fu Wai Hospital

    Beijing, 100037

  • Beijing Shijingshan Hospital

    Beijing, 100043

  • Beijing Tsinghua Changgung Hospital

    Beijing, 100044

  • Peking Union Medical College Hospital

    Beijing, 100730

  • First Hospital of Jilin University

    Changchun, 130021

  • Xiangya Hospital, Central South University

    Changsha, 410008

  • 2nd Xiangya Hospital of Central South University

    Changsha, 410011

  • Chinese Traditional Medicine Hospital of Sichuna Provinc

    Chengdu, 610000

  • Center Hospital of Dalian

    Dalian, 116033

  • Foshan Hospital of Southern Medical University

    Foshan, 528000

  • Fujian Provincal Hospital

    Fuzhou, 350001

  • Guangdong Provincial People's Hospital

    Guangzhou, 510080

  • The First Afiliated Hospital, Sun Yet-sen University

    Guangzhou, 510080

  • Wu Jing Zong Dui Hospital of Guangdong Province

    Guangzhou, 510507

  • The First Affiliated Hospital of Jinan University

    Guangzhou, 510630

  • The Affiliated Hospital of Hangzhou Normal University

    Hangzhou, 310000

  • Hangzhou First People's Hospital

    Hangzhou, 310006

  • Shandong Jiaotong Hospital

    Jinan, 250000

  • Center Hospital of Jinan

    Jinan, 250013

  • Qianfoshan Hospital affiliated to Shandong University

    Jinan, 250014

  • Shandong Provincial Hospital

    Jinan, 250021

  • Jining No.1 people's hospital

    Jining, 272111

  • The Second Affiliated Hospital to Nanchang University

    Nanchang, 330006

  • Zhongda Hospital Southeast University

    Nanjing, 210009

  • The affiliated hospital of medicalcollege qingdao university

    Qingdao, 266003

  • QingDao Municipal Hospital

    Qingdao, 266011

  • Qingdao Fuwai Hospital

    Qingdao, 266034

  • Qingdao Central Hospital

    Qingdao, 266042

  • Chinese People's Liberation Army 401 Hospital

    Qingdao, 266071

  • Huashan Hospital, Fudan University

    Shanghai, 200040

  • Shanghai Huadong Hospital

    Shanghai, 200040

  • Tongji Hospital, Tongji University

    Shanghai, 200065

  • Shanghai East Hospital, Tongji University China

    Shanghai, 200120

  • Renji Hospital Shanghai Jiaotong Univesrity School of Medicine

    Shanghai, 200127

  • Minhang District Central Hospital

    Shanghai, 201199

  • Songjiang Hospital

    Shanghai, 201600

  • Jiading Hospital

    Shanghai, 201800

  • Shengjing Hospital of China Medical University

    Shenyang, 110004

  • General Hospital of Shenyang Military Region

    Shenyang, 110015

  • People's Hospital of Liaoning Province

    Shenyang, 110016

  • The Forth People's Hospital of Shenzhen

    Shenzhen, 518033

  • The Second Hospital of Hebei Medical University

    Shijiazhuang, 050000

  • Hebei Provincial Tumor Hospital

    Shijiazhuang, 050011

  • SuZhou Kowloon Hospital

    Suzhou, 215021

  • The Central Hospital of Tai'an

    Tai’an, 250001

  • Shanxi Cardiovascular Hospital

    Taiyuan, 030024

  • Wu Jing Yi Xue Yuan Fu Shu Yi Yuan

    Tianjin, 300162

  • Wuhan Asia Heart Hospital

    Wuhan, 430022

  • Hubei Province Zhongshan Hospital

    Wuhan, 430032

  • First Affiliated Hospital of Xiamen University

    Xiamen, 361003

  • Xiamen Cardiovascular Hospital Xiamen University

    Xiamen, 361004

  • Xuzhou Central Hospital

    Xuzhou, 221009

  • Subei People's Hospital

    Yangzhou, 225001

  • zhengzhou No.7 people's Hospital

    Zhengzhou, 450006

  • Zhengzhou Central Hospital

    Zhengzhou, 450007

  • Zhengzhou People'S Hospital

    Zhengzhou, 450012

  • Yankuang Group General Hospital

    Zoucheng, 273500

Other trials in China

Japan44 sites
  • Asahi General Hospital

    Chiba, Asahi, 289-2511

  • Seikeikai New Tokyo Heart Clinic

    Chiba, Matsudo, 271-0077

  • Saiseikai Matsuyama Hospital

    Ehime, Matsuyama, 791-8026

  • Fukuiken Saiseikai Hospital

    Fukui, Fukui, 918-8503

  • Japanese Red Cross Fukuoka Hospital

    Fukuoka, Fukuoka, 815-8555

  • Aso Co.,Ltd Iizuka Hospital

    Fukuoka, Iizuka, 820-8505

  • Nakamura Cardiovascular Clinic

    Fukuoka, Itoshima, 819-1104

  • Fukuoka Tokushukai Medical Center

    Fukuoka, Kasuga, 816-0864

  • Shin Komonji Hospital

    Fukuoka, Kitakyushu, 800-0057

  • Fukuoka Shin Mizumaki Hospital

    Fukuoka, Onga, 807-0051

  • Matsuda Cardiovascular Clinic

    Hokkaido, Sapporo, 003-0026

  • Kobe City Medical Center General Hospital

    Hyogo, Kobe, 650-0047

  • Higashi Takarazuka Satoh Hospital

    Hyogo, Takarazuka, 665-0873

  • Houju Memorial Hospital

    Isikawa, Nomi, 923-1226

  • KKR Takamatsu Hospital

    Kagawa , Takamatsu, 760-0018

  • Kagawa Prefectural Shirotori Hospital

    Kagawa, Higashikagawa, 769-2788

  • Kokan Clinic

    Kanagawa, Kawasaki, 210-0852

  • Sekishinkai Kawasaki Saiwai Clinic

    Kanagawa, Kawasaki, 212-0016

  • Sagamihara Kyodo Hospital

    Kanagawa, Sagamihara, 252-5188

  • Social Medical Corporation Chikamorikai Chikamori Hospital

    Kochi, Kochi, 780-8522

  • Nakayama Clinic of I.M. and Cardiology, Kochi, Cardiology

    Kochi, Kochi, 781-5106

  • Sugimurakai Medical Association Sugimura Hospital

    Kumamoto, Kumamoto, 860-0811

  • Japan Community Health care Organization Kumamoto General Hospital

    Kumamoto, Yatsushiro, 866-8660

  • Uji-Tokushukai Medical Center

    Kyoto, Uji, 611-0041

  • Iida Municipal Hospital

    Nagano, Iida, 395-8502

  • Suwa Red Cross Hospital

    Nagano, Suwa, 392-8510

  • Tachikawa General Hospital

    Niigata, Nagaoka, 940-8621

  • Nozaki Tokushukai Hospital

    Osaka, Daito, 574-0074

  • Teramoto Memorial Hospital

    Osaka, Kawachinagano, 586-0017

  • Matsubara Tokushukai Hospital

    Osaka, Matsubara, 580-0032

  • Osaka Saiseikai Nakatsu Hospital

    Osaka, Osaka, 530-0012

  • Kitano Hospital

    Osaka, Osaka, 530-8480

  • Osaka Kaisei Hospital

    Osaka, Osaka, 532-0003

  • Ishinkai General Clinics

    Osaka, Yao, 581-0036

  • Medical corporation Chisei-kai Watanabe clinic

    Saitama, Okegawa, 363-0022

  • SAINO Clinic

    Saitama, Tokorozawa, 359-1141

  • Kusatsu Heart Center

    Shiga, Kusatsu, 525-0014

  • Shizuoka Tokushukai Hospital

    Shizuoka, Shizuoka, 421-0193

  • The Institute for Adult Deseases, Asahi Life Foundation

    Tokyo, Chuo-ku, 103-0002

  • Minamino Heart Clinic

    Tokyo, Hachioji, 192-0918

  • Shimizu Clinic

    Tokyo, Kodaira, 187-0003

  • The Cardiovascular Institute Hospital

    Tokyo, Minato-ku, 106-0031

  • YOGA Urban Clinic

    Tokyo, Setagaya, 158-0097

  • The University of Toyama Hospital

    Toyama, Toyama, 930-0194

Other trials in Japan

Canada37 sites
  • Antigonish Medical Associates Inc.

    Antigonish Nova Scotia, Nova Scotia, B2G 2C7

  • Foothills Medical Centre

    Calgary, Alberta, T2N 2T9

  • Cambridge Cardiac Care Inc.

    Cambridge, Ontario, N1R 6V6

  • Q & T Research Chicoutimi Inc

    Chicoutimi, Migration Data, G7H 7Y8

  • North Road Clinical Research

    Coquitlam, British Columbia, V3K 3V9

  • University of Alberta Hospital (University of Alberta)

    Edmonton, Alberta, T6G 2B7

  • West Lincoln Memorial Hospital

    Grimsby, Ontario, L3M 1P3

  • QEII Health Sciences Centre

    Halifax, Nova Scotia, B3H 3A7

  • Winterberry Family Medicine

    Hamilton, Ontario, L8J 0B6

  • Hamilton Medical Research Group

    Hamilton, Ontario, L8M 1K7

  • Hamilton General Hospital

    Hamilton, Ontario, L8S 4T1

  • Kelowna General Hospital

    Kelowna, British Columbia, V1Y 1E4

  • Clinique de Cardiologie de Levis

    Lévis, Quebec, G6V 4Z5

  • Victoria Hospital (LHSC)

    London, Ontario, N6A 5A5

  • Mississauga Clinical Research Centre

    Mississauga, Ontario, L5B 2P7

  • CHUM Hotel Dieu

    Montreal, Quebec, H2W 1T8

  • SKDS Research Incorporated

    Newmarket, Ontario, L3Y 5G8

  • M Heffernan Medicine Professional Corp.

    Oakville, Ontario, L6K 3W7

  • Oshawa Clinic Cardiology Department, Oshawa, Courtice

    Oshawa, Ontario, L1H 1B9

  • Ottawa Hospital - Civic Campus

    Ottawa, Ontario, K1Y 4E9

  • University of Ottawa Heart Institute Cardiology Research

    Ottawa, Ontario, K1Y 4W7

  • Recherche Clinique Sigma Inc.

    Québec, Quebec, G1G 3Y8

  • Crestwood Med & Dental Bldg

    Richmond, British Columbia, V7C 3V3

  • Saint John Regional Hospital

    Saint John, New Brunswick, E2L 4L2

  • IUCPQ (Laval University)

    Sainte-Foy, Quebec, G1V 4G5

  • Baycole Research

    Saskatoon, Saskatchewan, S7L 2W1

  • CHUS Fleurimont

    Sherbrooke, Quebec, J1H 5N4

  • CardioVasc HR Inc.

    St-Jean-sur-Richel, Migration Data, J3A 1C3

  • Eastern Health (MUN)

    St. John's, Newfoundland and Labrador, A1B 3V6

  • Aviva Clinical Trial Group Inc.

    Stoney Creek, Ontario, L8J 2V8

  • Ocean West Research Clinic Inc.

    Surrey, British Columbia, V3S 2N6

  • SGH Medical Mall

    Toronto, Ontario, M1P 2T7

  • Keele Medical Place

    Toronto, Ontario, M3M 3E5

  • Toronto General Hospital

    Toronto, Ontario, M4G 2C4

  • St. Michael's Hospital

    Toronto, Ontario, M5B 1W8

  • Toronto Western Hospital

    Toronto, Ontario, M5T 2S8

  • Victoria Cardiac Arrhythmia Trials Inc.

    Victoria, British Columbia, V8T 1Z4

Other trials in Canada

South Korea31 sites
  • Sejong General Hospital

    Bucheon-si, 14754

  • Dong-A University Hospital

    Busan, 49201

  • Kosin University Gospel Hospital

    Busan, 602-702

  • Pusan National Univ. Hosp

    Busan, 602-739

  • Inje University Haeundae Paik Hospital

    Busan, 612-896

  • Inje University Busan Paik Hospital

    Busan, 614-735

  • Keimyung University Dongsan Medical Center

    Daegu, 41931

  • Kyungpook National Univ. Hosp

    Daegu, 700-721

  • Daegu Fatima Hospital

    Daegu, 701-724

  • Yeungnam University Medical Center

    Daegu, 705-703

  • The Catholic University of Korea, Daejeon St.Mary's Hospital

    Daejeon, 301-723

  • Eulji University Hospital

    Daejeon, 302-799

  • Chonnam National University Hospital

    Gwangju, 501-757

  • Wonkwang University Hospital

    Iksan, 54538

  • Jeju National University Hospital

    Jeju City, 63241

  • Chonbuk National University Hospital

    Jeonju, 54907

  • Gyeongsang National University Hospital

    Jinju, 52727

  • Seoul National University Bundang Hospital

    Seongnam, 13620

  • Kyung Hee University Medical Center

    Seoul, 02447

  • Korea University Anam Hospital

    Seoul, 02841

  • Kangdong Sacred Heart Hospital

    Seoul, 05355

  • VHS Medical Center

    Seoul, 05368

  • The Catholic University of Korea, Seoul St.Mary's Hospital

    Seoul, 06591

  • Seoul National University Hospital

    Seoul, 110-744

  • Severance Hospital

    Seoul, 120-752

  • The Catholic University of Korea, Eunpyeong St. Mary's Hospital

    Seoul, 130-709

  • Samsung Medical Center

    Seoul, 135-710

  • Asan Medical Center

    Seoul, 138-736

  • Ajou University Hospital

    Suwon, 16499

  • Ulsan University Hospital

    Ulsan, 682-714

  • Pusan National University Yangsan Hospital

    Yangsan, 626-770

Other trials in South Korea

Brazil30 sites
  • Hospital Vera Cruz

    Belo Horizonte, 30140-092

  • Clinica Procardio Ltda

    Blumenau, 89010-500

  • Hospital do Coracao do Brasil

    Brasília, 70390-903

  • Instituto de Cardiologia do Distrito Federal

    Brasília, 70658-700

  • Hospital Angelina Caron

    Campina Grande do Sul, 83430-000

  • Centro Especializado em Cardiol Loema Instituto de Pesq Clin

    Campinas, 13010-001

  • HMCP - Hospital e Maternidade Celso Pierro - PUC-Campinas

    Campinas, 13060-904

  • Hospital Nossa Senhora de Pompeia

    Caxias do Sul, 95084-900

  • Irmandade da Santa Casa de Misericordia de Curitiba

    Curitiba, 80010-030

  • Barroso e Sebba Ltda

    Goiânia, 74223-130

  • CLINICOR-Clinica de Exames Cardiolog e Ecografias S S LTDA

    Maceió, 57051-500

  • Hospital São Vicente de Paulo

    Passo Fundo, 99010-080

  • Hospital de Clínicas de Porto Alegre

    Porto Alegre, 90035-903

  • Fundacao Universitaria de Cardiologia - Inst de Cardiologia

    Porto Alegre, 90620-001

  • Pronto Socorro Cardiológico de Pernambuco Prof. Luiz Tavares

    Recife, 50100-130

  • Hospital Copa D'or

    Rio de Janeiro, 22031-011

  • Fundacao Pro-Coracao FUNDACOR

    Rio de Janeiro, 22240-004

  • Instituto Cardiopulmonar da Bahia LTDA

    Salvador, 40170-130

  • Fundacao Bahiana de Cardiologia

    Salvador, 41810-010

  • Instituto de Ensino E Pesquisa Do Hospital Da Bahia

    Salvador, 41810-011

  • Instituto de Molestias Cardiovasculares - IMC

    São José do Rio Preto, 15015-210

  • H.S.J. Beneficência Portuguesa - São Paulo

    São Paulo, 01323-001

  • FGM - Clínica Paulista de Doenças Cardiovasculares

    São Paulo, 01327-010

  • Hcor - Hospital do Coracao

    São Paulo, 04004-030

  • Instituto Dante Pazzanese de Cardiologia

    São Paulo, 04012-180

  • Hospital das Clinicas da Faculdade de Medicina - FMUSP

    São Paulo, 05403-000

  • Hospital Santa Marcelina

    São Paulo, 08270-070

  • Hospital Sao Paulo UNIFESP

    São Paulo, 4038-031

  • Instituto de Molestias Cardiovasculares Tatui SP

    Tatuí, 18270-170

  • Santa Casa de Votuporanga

    Votuporanga, 15500-003

Other trials in Brazil

Russia25 sites
  • Altaiskyi Reg.Cardiologic Dispensary,Cardiology Dept,Barnaul

    Barnaul, 656055

  • Chelyabinsk State Med.Acad, Dept. of Clinical Pharmacology

    Chelyabinsk, 454092

  • Chita State Med.Acad, Consultative-Diagnostic-Polyclinic

    Chita, 672090

  • OJSC Municipal Instit.Dzerjinskiy City Hospital

    Dzerjinskiy, 140 091

  • Road Clin.Hosp.Irkutsk-Russian Railways,Cardio.&Therapy Dept

    Irkutsk, 664005

  • City Clin.Hosp.#9,Intern.Diseases&Fam.Practice Dept, Izhevsk

    Izhevsk, 426063

  • Res.Inst.-Compl.Iss.Cardi.Dis.

    Kemerovo, 650002

  • Municipal Instit. City Hosp. No.2, Policlinic Dept,Krasnodar

    Krasnodar, 350 012

  • GOU VPO MUZ City Clinical Hospital No. 20, Krasnoyarsk

    Krasnoyarsk, 660014

  • Moscow 1st State Med.Univ.n.a.I.M.Sechenov

    Moscow, 119992

  • Research Center n.a.A.N.Bakulev,Clin.-Diagnostic Dept,Moscow

    Moscow, 121552

  • Russian Cardiology Research and Production Complex, Moscow

    Moscow, 121552

  • Reg.Clin.Cardiological Dispen,Arrhythmology Dept,Novosibirsk

    Novosibirsk, 630047

  • Omsk State Medical Acad.,Internal Diseases&Fam.Practice Dept

    Omsk, 644043

  • Orenburg State Medical Academy of MoH, Therapy Department

    Orenburg, 460 000

  • Instit.Healthcare,MedicalSanitary Unit 9,n.a.M.A.Tverie,Perm

    Perm, 614990

  • Rostov Regional Clinical Hospital

    Rostov-on-Don, 344015

  • Ryazan Reg.Clin.Hosp.Internal Diseases&Policlin.Therapy Dept

    Ryazan, 390039

  • Fed.Centre of Heart, Blood & Endocrinology n.a. V.A. Almazov

    Saint Petersburg, 197341

  • Pokrovskaya City Hospital, St.Petersburg

    Saint Petersburg, 199106

  • Samara Regional Clinical Cardiology Clinic, Day Hosp. Dept.

    Samara, 443070

  • Samara State Medical University, Chair of Faculty Therapy

    Samara, 443099

  • Municipal Instit.Healthcare,City Policlinic #6,Therapy Dept.

    Saratov, 410015

  • Primorskiy Regional Clinical Hospital No. 1

    Vladivostok, 690091

  • GBUZ SO Ural Institute of Cardiology, Ekaterinburg

    Yekaterinburg, 620 144

Other trials in Russia

Mexico23 sites
  • Hospital General de Acapulco

    Acapulco de Juárez, Guerrero, 39570

  • Hospital Cardiologica Aguascalientes

    Aguascalientes, 20230

  • Christius Muguerza Hospital del Parque

    Chihuahua City, 31020

  • Centro Especializado de Investigación Medical Group Culiacan

    Culiacán, 80200

  • Centro para el Desarrollo de la Medicina y de Asist Med Espe

    Culiacán, 80230

  • Instituto Nacional de Cardiologia Ignacio Chavez

    Distrito Federal, 14080

  • Unidad Coronariana del Hospital General de Durango

    Durango, 34000

  • Centro de Investigación Especializada de Occidente S.C.

    Guadalajara, 44160

  • Clínica de Estudios Médicos S.C.

    Guadalajara, 44600

  • ICLE SC

    Guadalajara, 44600

  • Private Practice

    Guadalajara, 44670

  • Centro Medico de las Americas

    Mérida, Yucatán, 97000

  • Paracelsus S. A. de C.V.

    México, 03800

  • Hospital Metropolitano "Dr Bernardo Sepulveda"

    Monterrey, 66480

  • Clinica Miravalle

    Monterrey, Nuevo Leon, 64000

  • Unidad de Investigacion Clinica en Medicina, S.C.

    Monterrrey, 64718

  • Consultorio Privado J Arturo Maldonado Villalon

    Morelia, Michoacan, 58260

  • Clinical Medical Research S.C

    Orizaba, 94300

  • Instituto de Corazón de Querétaro

    Querétaro, 76000

  • Cardioarritmias e Investigación S.C

    San Luis Potosí City, 78200

  • Plaza Medical

    Tijuana, 22320

  • Servicios Diagnosticos en Medicina SC

    Toluca, Estado de Mexico, 52140

  • iBiomed

    Zapopan, 45030

Other trials in Mexico

Argentina16 sites
  • Consultorios Hematologicos SRL

    Buenos Aires, 1188

  • Clinica Coronel Suárez

    Buenos Aires, B7540GHD

  • Hospital Italiano de Buenos Aires

    Buenos Aires, C1181ACH

  • Instituto Cardiovascular de Buenos Aires

    Buenos Aires, C1428

  • Instituto Cardiovascular de Corrientes Juana Francisca Cabra

    Corrientes, C3400

  • Hospital Espanol de Mendonza

    Godoy Cruz, 5501

  • Hospital Privado de Comunidad

    Mar del Plata, 7602

  • DIM Clinica Privada

    Ramos Mejía, B1704ETD

  • Hospital Privado de Rosario

    Rosario, S2000GAP

  • Consultorio del Dr. Aiub

    San Isidro, 1642

  • Sanatorio San Lucas

    San Isidro, B1642DJG

  • Sanatorio 9 de Julio S.A.

    San Miguel de Tucumán, 4000

  • Centro Privado de Cardiología

    San Miguel de Tucumán, T4000NIL

  • Unidad Coronaria San Geronimo S.R.L.

    Santa Fe, 3000

  • Clinical Juncal

    Temperley, 1834

  • CEMEDIC - Centro de Especialidades Medicas

    Villa Luro, 1407

Other trials in Argentina

Colombia12 sites
  • Fundacion Hospital Infantil Universitario de San José

    Bogotá, 111221

  • Fundacion Clinica Shaio

    Bogotá

  • Simedics Ips

    Bogotá

  • Hospital Santa Clara E.S.E.

    Bogota DC

  • Fundacion Valle de Lilly

    Cali

  • Centro Médico Julián Coronel

    Cali -Valle Del Cauca

  • Centro de Diagnostico Cardilogico

    Cartagena

  • Fundacion Cardiovascular de Colombia

    Floridablanca, 68004

  • Asociacion IPS Medicos Internistas de Caldas

    Manizales

  • Ciclam Sas

    Medellín, 5001000

  • Ces Cardiología

    Medellín

  • Fundacion Cardiomet Centro de Investigaciones CEQUIN

    Quindío

Other trials in Colombia

Peru11 sites
  • Centro Medico Monte Carmelo

    Arequipa, 054

  • Hospital Nacional Daniel Alcides Carrion

    Bellavista, Callao 2

  • EsSalud - Hospital Nacional IV Alberto Sabogal Sologuren

    Callao, C2

  • Hospital Nacional Guillermo Almenara Irigoyen

    La Victoria, Lima-13

  • Hospital Nacional Edgardo Rebaglini Martins

    Lima, Lima-11

  • Clinica San Pablo

    Lima, Lima-33

  • Centro de Investigación en Diabetes, Obesidad y Nutrición

    Lince, Lima-14

  • Clinica Internacional

    San Borja, LIMA 41

  • Clinica Vesalio

    San Borja, lima-41

  • Clinica El Golf

    San Isidro, Lima-27

  • Clinica Medica Cayetano Heredia

    San Martín de Porres, Lima-31

Other trials in Peru

Lebanon10 sites
  • St.Charles Hospital

    Baabda, 50 Baabda

  • Makassed General Hospital

    Beirut, 11-6301

  • St. Georges Hospital

    Beirut, 166 378

  • Hotel Dieu de France Hospital

    Beirut, 166830

  • Rafik Hariri University Hospital

    Beirut, 5244

  • Al Rassoul Hospital, Beirut Cardiac Institute

    Beirut

  • American University of Beirut Medical Center

    Beirut

  • Bellvue Medical Center, Beirut

    Beirut

  • Notre Dame de Secours Hospital

    Byblos, 3

  • Hammoud Hospital University Medical Center

    Saida, 652

Other trials in Lebanon

Taiwan10 sites
  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    Kaohsiung City, 80756

  • Kaohsiung Chang Gung Memorial Hospital

    Kaohsiung City, 83301

  • Taichung Veterans General Hospital

    Taichung, 407

  • NCKUH

    Tainan, 704

  • National Taiwan University Hospital

    Taipei, 10002

  • Mackay Memorial Hospital

    Taipei, 10449

  • Cathay General Hospital

    Taipei, 106

  • Taipei Veterans General Hospital

    Taipei, 11217

  • Cheng Hsin General Hospital

    Taipei, 11220

  • Chang Gung Memorial Hospital(Linkou)

    Taoyuan, 330

Other trials in Taiwan

Saudi Arabia8 sites
  • King Fahad Military Hospital

    Dammam, 9862

  • King Fahad Hufuf Hospital

    Hofuf, 36441

  • Khamis Military Hospital

    Jeddah, 21424

  • King Abdul Aziz University Hospital

    Jeddah, 22254

  • Prince Salman Heart Center

    Riyadh, 11525

  • King Salman Hospital

    Riyadh, 11536

  • King Faisal Hospital

    Ta'if, 21944

  • Tabuk Military Hospital

    Tabuk, 71411

Other trials in Saudi Arabia

Chile6 sites
  • Hospital Clínico Fuerza Aérea de Chile

    Santiago, 7560171

  • Centro de Estudios Clinicos Barros Luco

    Santiago, 8910131

  • Hospital y CRS El Pino

    Santiago

  • CECMI Ltda

    Temuco, 4813299

  • CINVEC - Centro de Investigacion Clinica V Reg.,Vina del Mar

    Viña del Mar, 2520997

  • Clinica Tabancura

    Vitacura, 7650018

Other trials in Chile

South Africa5 sites
  • Dr. N. Ranjith

    Durban, 4052

  • Dr Mahesh Duki Research and Trial Site

    Durban, 4339

  • LCS Clinical Research Unit

    Johannesburg, 2021

  • Helderberg Research Institute

    Somerset West, Cape Town, 7130

  • Dr. Moodley and Dr. Sarvan

    Tongaat, 4400

Other trials in South Africa

Singapore4 sites
  • National University Hospital

    Singapore, 119074

  • National Heart Center

    Singapore, 169609

  • Novena Heart Centre

    Singapore, 307506

  • National Neuroscience Institute

    Singapore, 308433

Other trials in Singapore

United Arab Emirates4 sites
  • Al Ain Hospital

    Abu Dhabi, 1006

  • Sheikh Khalifa Medical City

    Abu Dhabi, 51900

  • Dubai Hospital

    Dubai, 7272

  • Al Qassimi Hospital

    Sharjah city, PO BOX 2804

Other trials in United Arab Emirates

Ecuador3 sites
  • Hospital Teodoro Maldonado Carbo

    Guayaquil, 190150

  • Unicormed SA

    Guayaquil

  • Hospital INTERVASCU

    Quito, 170122

Other trials in Ecuador

Hong Kong3 sites
  • Princess Margaret Hospital

    Hong Kong, 0

  • Queen Mary Hospital

    Hong Kong, 0

  • Prince of Wales Hospital

    Hong Kong, 999077

Other trials in Hong Kong

Venezuela1 site
  • Instituto de Clinicas y Urologia Tamanaco

    San Roman Caracas, 1060

Other trials in Venezuela

About this study

Official title: GLORIA - AF: Global Registry on Long-Term Oral Anti-thrombotic Treatment In Patients With Atrial Fibrillation (Phase II/III)

In this part of the Registry Program patients with non-valvular atrial fibrillation (AF) at risk for stroke are enrolled to characterize the target population and to collect real world data on important outcome events. For administrative purposes the study is divided into two protocol numbers: 1160.129 for all non-EU (European Union) and non-EEA (European Economic Area) countries, and 1160.136 for EU and EEA countries. The total number of patients enrolled in both protocols is estimated to be 48,000 patients, and all these patients will be included in the data analysis for study 1160.129.

Medical subject headings
Stroke, Atrial Fibrillation

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Incidence Rate of Composite Outcome (Stroke, Systemic Embolism, Myocardial Infarction, Life-threatening Bleeding Events and Vascular Death) - Phase II

    Incidence rate of composite outcome which includes events of Stroke, systemic embolism, myocardial infarction, life-threatening bleeding events and vascular death on all eligible patients excluding prescribed but not taken set that included Dabigatran etexilate (DE) of phase II only. In case of multiple events for a patient, the first event was considered.

    Measured: From baseline visit of Phase II until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 2 years.

  2. Incidence Rate of Composite Outcome (Stroke, Systemic Embolism, Myocardial Infarction, Life-threatening Bleeding Events and Vascular Death) - Phase III

    Incidence rate of composite outcome which includes events of Stroke, systemic embolism, myocardial infarction, life-threatening bleeding events and vascular death on restricted set that included Dabigatran etexilate (DE) of phase III and Vitamin K Antagonist (VKA) of phase III only. In case of multiple events for a patient, the first event was considered. Unknown cause of death was imputed by multiple imputation. Counts were based on the average of the 20 restricted data sets. The average of the 20 incidence rates from the 20 imputed datasets were used to obtain the point estimate of the incidence rate that is reported here. The bootstrapping approach was used to obtain the 95% confidence interval of the incidence rate.

    Measured: From baseline visit of phase III until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days/ VKA+ 6 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 3 years.

  3. Incidence Rate of Vascular Composite Outcome (Stroke, Systemic Embolism, Myocardial Infarction and Vascular Death) - Phase II

    Incidence rate of vascular composite outcome including events of stroke, systemic embolism, myocardial infarction and vascular death on all eligible patients excluding prescribed but not taken set that included Dabigatran etexilate (DE) of phase II only. In case of multiple events for a patient, the first event was considered.

    Measured: From baseline visit of Phase II until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 2 years.

  4. Incidence Rate of Vascular Composite Outcome (Stroke, Systemic Embolism, Myocardial Infarction and Vascular Death) - Phase III

    Incidence rate of vascular composite outcome including events of stroke, systemic embolism, myocardial infarction and vascular death on restricted set that included Dabigatran etexilate (DE) of phase III and Vitamin K Antagonist (VKA) of phase III only. In case of multiple events for a patient, the first event was considered. Unknown death was imputed by multiple imputation. Counts were based on the average of the 20 restricted data sets. The average of the 20 incidence rates from the 20 imputed datasets were used to obtain the point estimate of the incidence rate that is reported here. The bootstrapping approach was used to obtain the 95% confidence interval of the incidence rate.

    Measured: From baseline visit of phase III until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days/ VKA+ 6 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 3 years.

  5. Incidence Rate of Stroke or Systemic Embolism - Phase III

    Incidence rate of stroke or systemic embolism on restricted set that included Dabigatran etexilate (DE) of phase III and Vitamin K Antagonist (VKA) of phase III only.

    Measured: From baseline visit of phase III until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days/ VKA+ 6 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 3 years.

  6. Incidence Rate of Stroke - Phase II

    Incidence rate of stroke on all eligible patients excluding prescribed but not taken set for Dabigatran etexilate (DE) of phase II only is presented. Stroke is an acute onset of a focal neurological deficit of presumed vascular origin lasting for 24 hours or more or resulting in death. The stroke included ischemic or hemorrhagic or uncertain classification.

    Measured: From baseline visit of Phase II until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 2 years.

  7. Incidence Rate of Stroke - Phase III

    Incidence rate of stroke on restricted set that included Dabigatran etexilate (DE) of phase III and Vitamin K Antagonist (VKA) of phase III only. Stroke is an acute onset of a focal neurological deficit of presumed vascular origin lasting for 24 hours or more or resulting in death. The stroke included ischemic or hemorrhagic or uncertain classification.

    Measured: From baseline visit of phase III until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days/ VKA+ 6 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 3 years.

  8. Incidence Rate of Transient Ischaemic Attack (TIA) - Phase II

    Incidence rate of transient ischaemic attack (TIA) on on all eligible patients excluding prescribed but not taken set that included Dabigatran etexilate (DE) of phase II only is presented.

    Measured: From baseline visit of Phase II until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 2 years.

  9. Incidence Rate of Transient Ischaemic Attack (TIA) - Phase III

    Incidence rate of transient ischaemic attack (TIA) on restricted set that included Dabigatran etexilate (DE) of phase III and Vitamin K Antagonist (VKA) of phase III only.

    Measured: From baseline visit of phase III until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days/ VKA+ 6 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 3 years.

  10. Incidence Rate of Systemic Embolism (SE) - Phase II

    Incidence rate of systemic embolism (SE) on all eligible patients excluding prescribed but not taken set that included Dabigatran etexilate (DE) of phase II only is presented.

    Measured: From baseline visit of Phase II until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 2 years.

  11. Incidence Rate of Systemic Embolism (SE) - Phase III

    Incidence rate of systemic embolism (SE) on restricted set that included Dabigatran etexilate (DE) of phase III and Vitamin K Antagonist (VKA) of phase III only.

    Measured: From baseline visit of phase III until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days/ VKA+ 6 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 3 years.

  12. Incidence Rate of Pulmonary Embolism (PE) - Phase II

    Incidence rate of pulmonary embolism (PE) on all eligible patients excluding prescribed but not taken set that included Dabigatran etexilate (DE) of phase II only is presented.

    Measured: From baseline visit of Phase II until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 2 years.

  13. Incidence Rate of Pulmonary Embolism (PE) - Phase III

    Incidence rate of pulmonary embolism (PE) on restricted set that included Dabigatran etexilate (DE) of phase III and Vitamin K Antagonist (VKA) of phase III only.

    Measured: From baseline visit of phase III until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days/ VKA+ 6 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 3 years.

  14. Incidence Rate of Major Bleeding Events (MBE) - Phase II

    Incidence rate of major bleeding events (MBE) on all eligible patients excluding prescribed but not taken set that included Dabigatran etexilate (DE) of phase II only is presented. Major bleeding was defined as meeting one or more of the following criteria: Overt bleeding associated with a reduction in haemoglobin of at least 20 grams per liter or leading to a transfusion of at least 2 units of blood or packed cells; Symptomatic bleeding in a critical area or organ: Intraocular, intracranial, intraspinal or intramuscular with compartment syndrome, retroperitoneal bleeding, intra-articular bleeding or pericardial bleeding; Life-threatening bleeding.

    Measured: From baseline visit of Phase II until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 2 years.

  15. Incidence Rate of Major Bleeding Events (MBE) - Phase III

    Incidence rate of major bleeding events on restricted set that included Dabigatran etexilate (DE) of phase III and Vitamin K Antagonist (VKA) of phase III only. Major bleeding was defined as meeting one or more of the following criteria: Overt bleeding associated with a reduction in haemoglobin of at least 20 grams per liter or leading to a transfusion of at least 2 units of blood or packed cells; Symptomatic bleeding in a critical area or organ: Intraocular, intracranial, intraspinal or intramuscular with compartment syndrome, retroperitoneal bleeding, intra-articular bleeding or pericardial bleeding; Life-threatening bleeding.

    Measured: From baseline visit of phase III until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days/ VKA+ 6 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 3 years.

  16. Incidence Rate of Life-threatening Bleeding Events - Phase II

    Incidence rate of life-threatening bleeding events on all eligible patients excluding prescribed but not taken set that included Dabigatran etexilate (DE) of phase II only is presented. Life-threatening bleeding was defined as meeting one or more of the following criteria: Symptomatic intracranial bleed; Reduction in haemoglobin of at least 50 grams per liter; Transfusion of at least 4 units of blood or packed cells, associated with hypotension requiring the use of intravenous inotropic agents; Necessitated surgical intervention; Fatal bleeding.

    Measured: From baseline visit of Phase II until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 2 years.

  17. Incidence Rate of Life-threatening Bleeding Events - Phase III

    Incidence rate of life-threatening bleeding events on restricted set that included Dabigatran etexilate (DE) of phase III and Vitamin K Antagonist (VKA) of phase III only. Life-threatening bleeding was defined as meeting one or more of the following criteria: Symptomatic intracranial bleed; Reduction in haemoglobin of at least 50 grams per liter; Transfusion of at least 4 units of blood or packed cells, associated with hypotension requiring the use of intravenous inotropic agents; Necessitated surgical intervention; Fatal bleeding.

    Measured: From baseline visit of phase III until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days/ VKA+ 6 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 3 years.

  18. Incidence Rate of Myocardial Infarction (MI) - Phase II

    Incidence rate of myocardial infarction (MI) on all eligible patients excluding prescribed but not taken set that included Dabigatran etexilate (DE) of phase II only is presented.

    Measured: From baseline visit of Phase II until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 2 years.

  19. Incidence Rate of Myocardial Infarction (MI) - Phase III

    Incidence rate of myocardial infarction on restricted set that included Dabigatran etexilate (DE) of phase III and Vitamin K Antagonist (VKA) of phase III only.

    Measured: From baseline visit of phase III until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days/ VKA+ 6 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 3 years.

  20. Incidence Rate of All-cause Death - Phase II

    Incidence rate of all-cause death on all eligible patients excluding prescribed but not taken set that included Dabigatran etexilate (DE) of phase II only is presented.

    Measured: From baseline visit of Phase II until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 2 years.

  21. Incidence Rate of All-cause Death - Phase III

    Incidence rate of all-cause death on restricted set that included Dabigatran etexilate (DE) of phase III and Vitamin K Antagonist (VKA) of phase III only.

    Measured: From baseline visit of phase III until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days/ VKA+ 6 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 3 years.

  22. Incidence Rate of Vascular Death - Phase II

    Incidence rate of vascular death on all eligible patients excluding prescribed but not taken set that included Dabigatran etexilate (DE) of phase II only is presented.

    Measured: From baseline visit of Phase II until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 2 years.

  23. Incidence Rate of Vascular Death - Phase III

    Incidence rate of vascular death on restricted set that included Dabigatran etexilate (DE) of phase III and Vitamin K Antagonist (VKA) of phase III only.

    Measured: From baseline visit of phase III until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days/ VKA+ 6 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 3 years.

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted9 Nov 2011 (estimated)
  2. Study start7 Nov 2011
  3. Primary completion10 Jan 2020
  4. Study completion10 Jan 2020

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Prospective
Enrolment
37,235 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT01468701
Sponsor's protocol ID
1160.129
Status last verified
Mar 2021
First submitted
28 Oct 2011
Last updated
29 Mar 2021

Publications

  • Joddrell M, El-Bouri W, Harrison SL, Huisman MV, Lip GYH, Zheng Y; GLORIA-AFinvestigators. Machine learning for outcome prediction in patients with non-valvular atrial fibrillation from the GLORIA-AF registry. Sci Rep. 2024 Nov 7;14(1):27088. doi: 10.1038/s41598-024-78120-z.

    PubMed 39511367
  • Bergler-Klein J, Gotcheva N, Kalejs O, Kalarus Z, Kovacic D, Persic V, Shlyakhto E, Uuetoa T, Huisman MV, Lip GYH, Vinereanu D; GLORIA-AF Investigators. Antithrombotic Usage, Including Three-Year Outcomes With Dabigatran and Vitamin K Antagonists for Atrial Fibrillation, in Eastern Europe: A Descriptive Analysis From Phase 3 of the GLORIA-AF Registry. Am J Ther. 2024 Jan-Feb 01;31(1):e1-e12. doi: 10.1097/MJT.0000000000001655. Epub 2023 Jan 10.

    PubMed 38231576
  • Romiti GF, Corica B, Proietti M, Mei DA, Frydenlund J, Bisson A, Boriani G, Olshansky B, Chan YH, Huisman MV, Chao TF, Lip GYH; GLORIA-AF Investigators. Patterns of oral anticoagulant use and outcomes in Asian patients with atrial fibrillation: a post-hoc analysis from the GLORIA-AF Registry. EClinicalMedicine. 2023 Aug 25;63:102039. doi: 10.1016/j.eclinm.2023.102039. eCollection 2023 Sep.

    PubMed 37753446
  • Ding WY, Fawzy AM, Romiti GF, Proietti M, Pastori D, Huisman MV, Lip GYH; GLORIA-AF Investigators. Validating the predictive ability of the 2MACE score for major adverse cardiovascular events in patients with atrial fibrillation: results from phase II/III of the GLORIA-AF registry. J Thromb Thrombolysis. 2024 Jan;57(1):39-49. doi: 10.1007/s11239-023-02866-y. Epub 2023 Aug 11.

    PubMed 37566295
  • Liu X, Feng G, Marler SV, Huisman MV, Lip GYH, Ma C. Real world time trends in antithrombotic treatment for newly diagnosed atrial fibrillation in China: reports from the GLORIA-AF Phase III registry : Trends in antithrombotic therapy use in China. Thromb J. 2023 Aug 1;21(1):83. doi: 10.1186/s12959-023-00527-x.

    PubMed 37528405
  • Ding WY, Lane DA, Gupta D, Huisman MV, Lip GYH; GLORIA-AF Investigators. Incidence and Risk Factors for Residual Adverse Events Despite Anticoagulation in Atrial Fibrillation: Results From Phase II/III of the GLORIA-AF Registry. J Am Heart Assoc. 2022 Aug 2;11(15):e026410. doi: 10.1161/JAHA.122.026410. Epub 2022 Jul 25.

    PubMed 35876418
  • Ding WY, Calvert P, Gupta D, Huisman MV, Lip GYH; GLORIA-AF Investigators. Impact of early ablation of atrial fibrillation on long-term outcomes: results from phase II/III of the GLORIA-AF registry. Clin Res Cardiol. 2022 Sep;111(9):1057-1068. doi: 10.1007/s00392-022-02022-1. Epub 2022 Apr 29.

    PubMed 35488127
  • Lip GYH, Kotalczyk A, Teutsch C, Diener HC, Dubner SJ, Halperin JL, Ma CS, Rothman KJ, Marler S, Gurusamy VK, Huisman MV; GLORIA-AF Investigators. Comparative effectiveness and safety of non-vitamin K antagonists for atrial fibrillation in clinical practice: GLORIA-AF Registry. Clin Res Cardiol. 2022 May;111(5):560-573. doi: 10.1007/s00392-022-01996-2. Epub 2022 Mar 16.

    PubMed 35294625
  • Huisman MV, Teutsch C, Lu S, Diener HC, Dubner SJ, Halperin JL, Ma CS, Rothman KJ, Lohmann R, Gurusamy VK, Bartels DB, Lip GYH; GLORIA-AF Investigators. Dabigatran versus vitamin K antagonists for atrial fibrillation in clinical practice: final outcomes from Phase III of the GLORIA-AF registry. Clin Res Cardiol. 2022 May;111(5):548-559. doi: 10.1007/s00392-021-01957-1. Epub 2022 Mar 16.

    PubMed 35294623
  • Bayer V, Kotalczyk A, Kea B, Teutsch C, Larsen P, Button D, Huisman MV, Lip GYH, Olshansky B. Global Oral Anticoagulation Use Varies by Region in Patients With Recent Diagnosis of Atrial Fibrillation: The GLORIA-AF Phase III Registry. J Am Heart Assoc. 2022 Mar 15;11(6):e023907. doi: 10.1161/JAHA.121.023907. Epub 2022 Mar 4.

    PubMed 35243870
  • Lopez-Sendon JL, Alonso-Rodriguez D, Baron-Esquivias G, Cosin-Sales J, Marin F, Galera-Llorca J, Jimenez N, Marler S, Huisman MV, Lip GYH; Spanish GLORIA-AF investigators. Gender differences in antithrombotic treatment in patients with atrial fibrillation from Spain versus the rest of Western Europe. GLORIA-AF Program. Med Clin (Barc). 2022 Aug 26;159(4):177-182. doi: 10.1016/j.medcli.2021.09.016. Epub 2021 Dec 8. English, Spanish.

    PubMed 34895750
  • Ntaios G, Huisman MV, Diener HC, Halperin JL, Teutsch C, Marler S, Gurusamy VK, Thompson M, Lip GYH, Olshansky B; GLORIA-AF Investigators. Anticoagulant selection in relation to the SAMe-TT2R2 score in patients with atrial fibrillation: The GLORIA-AF registry. Hellenic J Cardiol. 2021 Mar-Apr;62(2):152-157. doi: 10.1016/j.hjc.2020.11.009. Epub 2020 Dec 15.

    PubMed 33338644
  • Mazurek M, Halperin JL, Huisman MV, Diener HC, Dubner SJ, Ma CS, Rothman KJ, Healey JS, Teutsch C, Paquette M, Franca LR, Lu S, Bartels DB, Lip GYH. Antithrombotic treatment for newly diagnosed atrial fibrillation in relation to patient age: the GLORIA-AF registry programme. Europace. 2020 Jan 1;22(1):47-57. doi: 10.1093/europace/euz278.

    PubMed 31651951
  • Mazurek M, Huisman MV, Rothman KJ, Paquette M, Teutsch C, Diener HC, Dubner SJ, Halperin JL, Zint K, Franca LR, Lu S, Lip GYH; GLORIA-AF Investigators. Gender Differences in Antithrombotic Treatment for Newly Diagnosed Atrial Fibrillation: The GLORIA-AF Registry Program. Am J Med. 2018 Aug;131(8):945-955.e3. doi: 10.1016/j.amjmed.2018.03.024. Epub 2018 Apr 11.

    PubMed 29654720
  • Huisman MV, Rothman KJ, Paquette M, Teutsch C, Diener HC, Dubner SJ, Halperin JL, Ma CS, Zint K, Elsaesser A, Lu S, Bartels DB, Lip GYH; GLORIA-AF Investigators. Two-year follow-up of patients treated with dabigatran for stroke prevention in atrial fibrillation: Global Registry on Long-Term Antithrombotic Treatment in Patients with Atrial Fibrillation (GLORIA-AF) registry. Am Heart J. 2018 Apr;198:55-63. doi: 10.1016/j.ahj.2017.08.018. Epub 2017 Aug 31.

    PubMed 29653649

Questions about this trial

What is this clinical trial studying?

An observational study of Stroke and Atrial Fibrillation, run by Boehringer Ingelheim at 666 sites in 21 countries.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 29 Mar 2021. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 666 sites in United States, China, Japan, Canada, South Korea and 16 more countries. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

Yes. Results are posted in the registry (first posted 29 Mar 2021). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Incidence Rate of Composite Outcome (Stroke, Systemic Embolism, Myocardial Infarction, Life-threatening Bleeding Events and Vascular Death) - Phase II (time frame: From baseline visit of Phase II until end of initial treatment regimen episode (minimum date of permanent stop of DE + 3 days, start date of other treatments - 1 day, and date of study completion/discontinuation), up to 2 years.). The study lists 23 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT01468701, which also lists 17 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Mar 2021.

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GLORIA-AF Registry Program - Second and Third Phases | AzTrials