Research institution
University of Kansas Medical Center Clinical Trials
Studies where University of Kansas Medical Center is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 101Smoking Cessation
Contingency Management to Promote Smoking Cessation Study
Adherence to medication and counseling are strong predictors of smoking cessation success. To provide these two components of care, healthcare providers typically provide people who smoke with prescriptions for cessation…
- Trial name
- NCT07685899
- Testing
- Health Rewards, Control
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Kansas Medical Center
Breast Cancer
De-Escalation of Axillary Management in Advanced Nodal Disease
This is a prospective, phase 2, single arm trial to evaluate whether Axillary Lymph Node Dissection (ALND) can be safely omitted for patients with cN2 and cN3 breast cancer who achieve a complete clinical response on exam with a…
- Trial name
- DEMAND (NCT07643584)
- Testing
- Axillary Surgery
- Volunteers
- 120 people
- Sponsor
- University of Kansas Medical Center
Smoking Reduction
Switching to E-cigarettes in Smokers Not Interested in Quitting
The objectives of this application are to 1) compare short- and long-term harm reduction and abuse liability potential of a nicotine salt pod-based electronic cigarettes (EC) in adult (AA) exclusive EC, dual cig-EC, and exclusive…
- Trial name
- NCT05703672
- Testing
- Varenicline Tartrate, Electronic cigarette
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Motoric Cognitive Risk Syndrome
Motor-Cognitive Training for Motoric Cognitive Risk Syndrome
The goal of this clinical trial is to investigate if combined motor-cognitive training can improve motor and cognitive symptoms in older adults with motoric cognitive risk syndrome.
- Trial name
- VRTT for MCR (NCT07223905)
- Testing
- Virtual Reality Treadmill Training, Treadmill Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Kansas Medical Center
Multiple Sclerosis, Insomnia
Comparing Telehealth-Delivered CBT-I to Web-Based CBT-I to Enhance Sleep, Reduce Fatigue, and Promote Neuroprotection
The objective of this RCT is to assess the efficacy of one-on-one telehealth CBT-I (tCBT-I) compared to web-based CBT-I (wCBT-I) and treatment as usual (TAU) to improve sleep outcomes (Aim 1), fatigue and quality of life (Aim 2)…
- Trial name
- CLEAR (NCT06434571)
- Testing
- Telehealth cognitive behavioral therapy for insomnia (tCBT-I), Web-based cognitive behavioral therapy for insomnia (wCBT-I), Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Kansas Medical Center
Osteoarthritis, Knee, Diabetes Mellitus, Type 2
Knee Osteoarthritis Treatment With Zilretta vs. Kenalog in the Context of Type II Diabetes
A Phase 2 Randomized Study to Evaluate the Effects of triamcinolone acetonide extended-release (TA-ER; Zilretta) vs. triamcinolone acetonide immediate-release (TA-IR; Kenalog) on Blood Glucose Levels in Diabetic Subjects with…
- Trial name
- NCT06478186
- Testing
- triamcinolone acetonide extended-release injectable suspension; TCA-ER, Triamcinolone Acetonide- Immediate Release;TCA-IR
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Kansas Medical Center
Cancer, Cancer Survivorship
AYA Cancer Transitions Program
This is a single-arm, minimal-risk, interventional behavioral clinical trial embedding structured transition support for adolescent and young adult (AYA) survivors of pediatric cancer transitioning into adult-focused survivorship…
- Conditions
- Cancer, Cancer Survivorship, Adolescent and Young Adult Cancer Survivors, Transitions of Care
- Trial name
- NCT07865013
- Testing
- Transitions Program
- Volunteers
- 100 people
- Sponsor
- University of Kansas Medical Center
Knee Osteoarthritis, Patellofemoral Pain (PFPS)
Assessing the Association Between WBCT PFJ Morphological Metrics and Knee Symptoms
Patellofemoral joint (PFJ) pain is a common, often chronic, aching pain behind or around the kneecap, frequently called "runner's knee".
- Trial name
- NCT07472088
- Testing
- WBCT
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Kansas Medical Center
Chronic Low-back Pain
Evaluation of Multi-Tined Expandable Electrode (MEE) Efficacy and Safety in Treatment of Lumbar Facet Arthropathy by Radiofrequency Neurotomies Compared to Conservative Medical Management.
The purpose of this study is to better understand how people feel after a radiofrequency ablation standard of care surgery using a different type of needle (multi-tined expandable electrode/MEE) in comparison to receiving…
- Trial name
- MEE (NCT04730700)
- Testing
- Radiofrequency Ablation with MEE, Conventional Medical Management
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Kansas Medical Center
Stone, Kidney
FANS-Optimization of Irrigation and Suction Parameters in RIRS
Kidney stones are commonly treated with flexible ureteroscopy, a minimally invasive procedure in which a small scope is passed through the urinary tract to reach and treat stones in the kidney.
- Trial name
- NCT07840482
- Testing
- ClearPetra™ FANS - High-Flow Setting, ClearPetra™ FANS - Moderate-Flow Setting
- Volunteers
- 100 people
- Sponsor
- University of Kansas Medical Center
Completed, with results posted
All 97Type 2 Diabetes
Intermittent Fasting for the Treatment of Type 2 Diabetes Mellitus
To test whether a lifestyle program featuring one of two forms of intermittent fasting (IER or TRE) can feasibly and effectively improve glycemia in patients with type 2 diabetes, and potentially induce diabetes remission.
- Trial name
- NCT05860413
- Testing
- Intermittent energy restriction (IER), Time Restricted Eating (TRE)
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Kansas Medical Center
Alzheimer Disease
Therapeutic Diets in Alzheimer's Disease
By doing this study, researchers hope to learn how the ketogenic and Therapeutic Lifestyles Changes diets affect cognition in patients with Alzheimer's disease.
- Trial name
- TDAD (NCT03860792)
- Testing
- Ketogenic Diet, Therapeutic Lifestyles Changes Diet
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Kansas Medical Center
Diet Quality
Nutricity: An mHealth Nutrition Intervention to Improve Diet Quality Among Latino Children
The overall objective of this application is to pilot test an mHealth nutrition intervention within pediatric clinics serving Latino families and evaluate its potential for implementation.
- Trial name
- NCT06266468
- Testing
- Nutricity
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Autism
Testing Swim Instruction for Autistic Children
The goal of this clinical trial is to compare the effects of a specialized swimming and water-safety program (Sensory Enhanced Aquatics) and standard swimming lessons for autistic children.
- Trial name
- NCT06216613
- Testing
- Sensory Enhanced Aquatics, Standard Swim Lessons
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Kansas Medical Center
Brain Health, Gestational Hypertension
Brain Health in Midlife
The purpose of this study is to learn if hypertensive disorders during pregnancy affects brain health in midlife.
- Conditions
- Brain Health, Gestational Hypertension, Alzheimer Disease, Dementia
- Trial name
- ADORE BRAIN (NCT06640842)
- Testing
- A combination of various tests and biomarkers will be completed to understand the effect of hypertensive disorders of pregnancy on brain health in midlife.
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center