Research institution
Peking Union Medical College Hospital Clinical Trials
Studies where Peking Union Medical College Hospital is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 303Cervical Cancer Screening
Use of cfDNA in Monitoring and Guiding Treatment for Cervical Cancer
This is a prospective, single-center, observational cohort study that plans to enroll 100 women aged 18 years or older with histologically confirmed cervical cancer who are scheduled to receive radical surgery, radiotherapy, or…
- Trial name
- NCT07919431
- Testing
- Low-depth cfDNA fragmentomics testing
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Colorectal Cancer
A Patient-Derived 3D Bioprinted Colorectal Cancer-Stroma-Immune Triad Model Uncovers Microenvironmental Mechanisms of Chemoresistance and Immune Evasion
Colorectal cancer (CRC) has shifted toward a patient-personalized precision medicine paradigm; however, the high heterogeneity and complex tumor microenvironment (TME) of CRC restrict the development of individualized therapy…
- Trial name
- NCT07919418
- Testing
- Surgical resection and adjuvant chemotherapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Atrial Fibrillation, Atrial Fibrillation Recurrent
Atrial Fibrillation Patients Treated With Catheter Ablation
This is a single-center prospective observational cohort study of atrial fibrillation patients treated with radiofrequency ablation.
- Trial name
- NCT05266144
- Testing
- radiofrequency ablation
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking Union Medical College Hospital
Gestational Trophoblastic Neoplasia
Camrelizumab Plus Apatinib in Patients With High-risk Gestational Trophoblastic Neoplasia
The purpose of this study is to evaluate the efficacy and safety of camrelizumab and apatinib as combination therapy in patients with ultra high-risk (Cohort A) and high-risk chemo-refractory or relapsed (Cohort B) gestational…
- Trial name
- NCT05139095
- Testing
- Camrelizumab plus apatinib CohortA, Camrelizumab plus apatinib Cohort B
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking Union Medical College Hospital
Cervical Cancer, Adaptive Radiotherapy
Moderated Hypofractionated Online Adaptive Radiotherapy in Cervical Cancer
The most common external beam radiotherapy fractionation scheme for cervical cancer is 45-50.4 Gy delivered in 25-28 fractions. However, prolonged treatment duration can lead to insufficient availability of medical resources.
- Trial name
- NCT06641635
- Testing
- Moderated hypofractionated online adaptive radiotherapy, Conventional radiotherapy
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Peking Union Medical College Hospital
Cushing s Syndrome
Diagnostic Value of CXCR4-targeted PET/CT in ACTH-dependent and Independent Cushing's Syndrome
In previous clinical practice, 68Ga-Pentixafor PET/CT has demonstrated promising diagnostic utility in various neuroendocrine tumors by targeting CXCR4, a chemokine receptor overexpressed in several ACTH-secreting neoplasms.
- Trial name
- NCT07350707
- Testing
- 68Ga-Pentixafor
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Peking Union Medical College Hospital
Glycogen Storage Disease
Neurocognitive Function and Neuroimaging Features in Patients With Glycogen Storage Diseases
The goal of this observational study is to learn about cognitive function and brain imaging findings in people with glycogen storage disease (GSD).
- Trial name
- NEURO-GSD (NCT07908212)
- Where
- China
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Cervical Neuroendocrine Carcinoma
Immunotherapy in Neuroendocrine Carcinoma of the Cervix
This retrospective study reviews existing medical records. No new treatments or tests are given. The study asks how well immunotherapy worked for people with a rare cancer called neuroendocrine carcinoma of the cervix.
- Trial name
- NCT07911423
- Testing
- No study intervention; observational study.
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking Union Medical College Hospital
Cerebral Small Vessel Disease, Ischemic Stroke
Treatment of Acute Ischemic Stroke With Edaravone Dexborneol Sublingual Tablets in Small Vessel Disease
This study is a multicenter, randomized, double-blind, placebo-controlled trial designed to evaluate the efficacy and safety of Edaravone Dexborneol Sublingual Tablets in patients with acute ischemic stroke due to small vessel…
- Trial name
- TASTE-SVD (NCT06674460)
- Testing
- Edaravone Dexborneol Sublingual Tablets
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking Union Medical College Hospital
Gastrointestinal Neuroendocrine Carcinoma, Adjuvant Treatment
Oxaliplatin-Based Adjuvant Therapy for Gastrointestinal Neuroendocrine Carcinoma**
Patients with pathologically-confirmed gastrointestinal neuroendocrine carcinoma will be enrolled, to explore the efficacy and safety of oxaliplatin-based doublet chemotherapy in the adjuvant treatment of gastrointestinal…
- Conditions
- Gastrointestinal Neuroendocrine Carcinoma, Adjuvant Treatment, Resection
- Trial name
- NCT07891572
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Peking Union Medical College Hospital
Completed, with results posted
All 7Interstitial Lung Disease, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Anti-neutrophil Cytoplasmic Antibody in Interstitial Lung Disease.
The purpose of this study is to investigate the clinical features and long-term outcome of anti-neutrophil cytoplasmic antibody (ANCA)-positive interstitial lung disease (ILD) and assess the difference between microscopic…
- Trial name
- NCT04413149
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking Union Medical College Hospital
Major Surgery Under General Anesthesia
Perioperative Accuracy of the Raiing Wireless Axillary Thermometer
A new wireless axillary thermometer from Raiing Medical uses a proprietary system, iThermonitor (WT701), to provide better estimates of core temperature than a conventional axillary probe.
- Trial name
- NCT02756910
- Testing
- iThermonitor (WT701)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking Union Medical College Hospital
Major Surgery Under General Anesthesia
The Effects of Ambient Temperature and Forced-air Warming on Intraoperative Core Temperature
The purpose of this study is to determine: 1. the effect of ambient temperature on the rate of core temperature change from 1 to 3 hours after induction of anesthesia (linear phase of the hypothermia curve) in major operations…
- Trial name
- NCT02715076
- Testing
- Ambient Temperature 19°C, Ambient Temperature 21°C, Ambient Temperature 23°C
- Where
- China
- Volunteers
- 292 people
- Sponsor
- Peking Union Medical College Hospital
Stroke
Cerebral Reorganization of Stroke Patients After Repetitive Transcranial Magnetic Stimulation by Neuroimaging Analysis
The study aimed to figure out brain structural and functional reorganization evidence after repetitive transcranial magnetic stimulation through the method of neuroimaging brain network analysis, such as resting-state functional…
- Trial name
- NCT03163758
- Testing
- real Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Peking Union Medical College Hospital
Hypotension, Shock
Transcutaneous pO2, Transcutaneous pCO2 and Central Venous SO2 Variations to Define Fluid Responsiveness
Fluid challenge is often carried out in critical ill patients. Its responsiveness usually requires invasive monitoring. To use non-invasive methods is very tempting.
- Conditions
- Hypotension, Shock, Fluid Challenge, Fluid Responsiveness
- Trial name
- NCT01941472
- Testing
- fluid challenge
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking Union Medical College Hospital