Country
Clinical Trials in Ethiopia
Studies with at least one site in Ethiopia. Open a trial for its sites in Ethiopia, who to contact and who can take part.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 55Cutaneous Leishmaniasis
Feasibility of Integrating Thermotherapy for Treatment of Cutaneous Leishmaniasis in Primary Health Care Setup
This study will look at how feasible it is to use thermotherapy (TT) as a treatment for skin(cutaneous) leishmaniasis (CL) in health centers in the Sodo and South Sodo districts, Ethiopia.
- Trial name
- TTCL (NCT06746350)
- Testing
- Thermotherapy
- Where
- Ethiopia
- Volunteers
- 103 people
- Sponsor
- Armauer Hansen Research Institute, Ethiopia
Major Depressive Disorder (MDD)
Prescribing the Right Agent for Depression in Adults
Depression is a common mental health problem affecting almost 300 million people worldwide. Antidepressants are recommended as one of the first line treatments for people with moderate-to-severe symptoms of depression.
- Trial name
- PRADA (NCT07796295)
- Testing
- PRADA Tool, PETRUSHKA Tool
- Where
- 3 sites in Ethiopia, Pakistan and 1 more
- Volunteers
- 2,142 people
- Sponsor
- University of Oxford
Dietary Intake, Sexual and Reproductive Health
Advancing Female University Students' Health Through Mobile Technology in Ethiopia
Background: Female university students in Ethiopia experience a high burden of sexual and reproductive health, nutrition, and psychosocial problems, exacerbated by limited access to essential health services and support.
- Conditions
- Dietary Intake, Sexual and Reproductive Health, Psychosocial Wellbeing
- Trial name
- EMPOWER (NCT07746791)
- Testing
- Behavioural change intervention will be provided through mobile application, Routine care
- Where
- Ethiopia
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- Bahir Dar University
Tuberculosis, Pulmonary
Digital Health Intervention to Improve TPT Uptake
Despite the evidence of the prevention and control measures of tuberculosis (TB), it still has an impact on the health, social, and economic aspects of the population.
- Trial name
- DHiTPT (NCT07313995)
- Testing
- Digital health intervention
- Where
- 14 sites in Ethiopia
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Arba Minch University
Plasmodium Vivax Malaria Without Complication, Plasmodium Falciparum Malaria (Uncomplicated)
Ethiopian Antimalarial Therapeutic Efficacy Study 2026
Background: The WHO recommends monitoring the efficacy of antimalarial drugs at least once every two years after implementation.
- Trial name
- TES2026 (NCT07840898)
- Testing
- Artemether-Lumefantrine + Primaquine and Chloroquine + Primaquine
- Where
- Ethiopia
- Volunteers
- 1,200 people
- Sponsor
- Ethiopian Public Health Institute
Acute Malnutrition, Severe, Malnutrition, Child
Increasing the Coverage of Severe Acute Malnutrition (SAM) Treatment in Ethiopia
The R-SWITCH intervention aims to address the low coverage of treatment for severe wasting (SAM) by leveraging existing community groups to deliver an integrated package focused on prevention, screening, referral, and treatment…
- Conditions
- Acute Malnutrition, Severe, Malnutrition, Child, Wasting
- Trial name
- R-SWITCH (NCT06380504)
- Testing
- R-SWITCH integrated intervention package
- Where
- Ethiopia
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Malaria Vivax, Malaria Falciparum
Serological Testing and Treatment for Plasmodium Vivax Malaria: a Trial in Ethiopia and Madagascar
The resilience of P. vivax to malaria elimination efforts is due to its ability to form dormant liver stages (hypnozoites) that reactivate weeks to months after the initial infection causing recurrent episodes of malaria…
- Conditions
- Malaria Vivax, Malaria Falciparum, Plasmodium Vivax, Plasmodium Falciparum
- Trial name
- PvSTATEM (NCT06923592)
- Testing
- PvSeroTAT, Control
- Where
- 2 sites in Ethiopia, Madagascar
- Volunteers
- 19,200 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Perinatal Depression, Social Support
Midwife-led Cognitive Behavioral Intervention for Perinatal Depression. Multisite RCT
Perinatal depression(PND), or depression during pregnancy and within one year following childbirth, is the most burdensome maternal mental illness. Women in low-income countries like Ethiopia have suffered from the disease.
- Conditions
- Perinatal Depression, Social Support, Perceived Stress
- Trial name
- NCT07800299
- Testing
- Midwife-led Cognitive Behaviroal Intervention
- Where
- 3 sites in Ethiopia
- Volunteers
- 192 people
- Sponsor
- The Hong Kong Polytechnic University
Malaria Fever
Non-invasive Malaria Diagnostic Data Collection in Ethiopia
This project supports the development of a non-invasive diagnostic tool for malaria, focusing on validating the link between VOCs (volatile organic compounds) and malaria infection using thermodynamic sensors.
- Trial name
- NCT07456969
- Where
- Ethiopia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Pregnancy Related, Tuberculosis Infection
Effects of Tuberculosis Infection on Development and Function of the Placenta
The goal of this observational study is to understand how tuberculosis (TB) infection impacts the function and development of the placenta, and whether TB infection can contribute to pregnancy-related disorders through effects on…
- Conditions
- Pregnancy Related, Tuberculosis Infection, Placenta Diseases
- Trial name
- NCT06352970
- Testing
- TB infection
- Where
- Ethiopia
- Volunteers
- 500 people
- Sponsor
- Lund University
Completed, with results posted
All –Trachomatous Trichiasis (TT), Eye Diseases
FLuorometholone as Adjunctive MEdical Therapy for TT Surgery (FLAME) Trial
This study aims : To assess the efficacy of fluorometholone 0.1% one drop twice daily for four weeks in reducing the incidence of post-operative trachomatous trichiasis (TT) when given as adjunctive therapy with TT surgery in the…
- Conditions
- Trachomatous Trichiasis (TT), Eye Diseases, Eyelid Diseases, Trachomatous
- Trial name
- FLAME (NCT04149210)
- Testing
- Fluorometholone 0.1% Oph Susp, Artificial Tears
- Where
- Ethiopia
- Volunteers
- 2,410 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Peer Influence, Medication Adherence
Effect of Peer Support Intervention on Medication Adherence, Self-care and Knowledge Among Patients With Diabetes
The goal of this interventional study is to learn about the effect of a peer support group intervention on adherence, self-care practice, and knowledge among diabetic patients on follow-up care.
- Conditions
- Peer Influence, Medication Adherence, Self Care
- Trial name
- DM (NCT07145983)
- Testing
- Structured Diabetes Education on medication Adherence and self care
- Where
- Ethiopia
- Volunteers
- 120 people
- Sponsor
- Addis Ababa University
Trichiasis, Surgery
Repeat Surgery for Patients With Post-operative Trachomatous Trichiasis Trial
The objective of this study is to determine if there is a significant difference in post-operative trichiasis at 12 months comparing a new procedure, the Bevel/rotate/advance procedure (BRAP), to the Trabut procedure among repeat…
- Trial name
- PTT (NCT03886519)
- Testing
- BRAP (Bevel/rotate/advance procedure), Trabut
- Where
- Ethiopia
- Volunteers
- 886 people
- Sponsor
- University of North Carolina, Chapel Hill
Trichiasis, Surgery
Maximizing Trichiasis Surgery Success
The purpose of this study is to determine whether the rate of post-operative trachomatous trichiasis differs significantly between bilamellar tarsal rotation surgery with an incision height of 3 mm, bilamellar tarsal rotation…
- Trial name
- MTSS (NCT03100747)
- Testing
- Bilamellar 3 mm, Bilamellar 5 mm, Trabut 3 mm
- Where
- Ethiopia
- Volunteers
- 4,914 people
- Sponsor
- University of North Carolina, Chapel Hill
MDR-TB
The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TB
Tuberculosis (TB) is a common, infectious, bacterial disease that is spread when an infected person transmits their saliva through the air by coughing or sneezing.
- Trial name
- STREAM (NCT02409290)
- Testing
- Regimen A locally-used WHO-approved MDR-TB regimen (2011 guideline), Moxifloxacin, Clofazimine
- Where
- 13 sites in Ethiopia, Georgia and 5 more
- Volunteers
- 588 people
- Sponsor
- IUATLD, Inc