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Clinical Trials in Cameroon

Studies with at least one site in Cameroon. Open a trial for its sites in Cameroon, who to contact and who can take part.

167 registered studies

In numbers

Open to volunteers
14
Active
18
With results posted
13
All registered
167

Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.

Open to volunteers

All 14
  • Bleeding Post-mechanical Valve Replacement, Thromboembolism Post-mechanical Valve Replacement

    Low INR to Minimize Bleeding With Mechanical Valves Trial

    • Recruiting
    • Age: 18 years and older
    • Phase 3

    This study evaluates the use of a lower INR target (1.5 to 2.5) in patients with a mechanical bileaflet heart valve in the aortic position.

    Trial name
    LIMIT (NCT03636295)
    Testing
    Warfarin
    Where
    45 sites in Belgium, Botswana and 16 more
    Volunteers
    2,625 people
    Sponsor
    Population Health Research Institute
    Can I take part? LIMIT
  • Cervical Cancers

    Use Misoprostol to Optimize Prevention of Cervical Cancer

    • Recruiting
    • Age: 25 years and older
    • Pill or oral medicine

    This is a double-blind randomized controlled trial of 420 non-pregnant women undergoing cancer screening by visual inspection with acetic acid (VIA) who have Type 3 transformation zone (TZ) and randomized to receive either…

    Trial name
    MISOPCx (NCT06669533)
    Testing
    Misoprostol
    Where
    Cameroon
    Volunteers
    420 people, healthy volunteers welcome
    Sponsor
    University of Alabama at Birmingham
    Can I take part? MISOPCx
  • HIV-1-infection

    DORAvirine Versus DOlutegravir Based Antiretroviral Regimens in Treatment-naïve People Living With HIV-1 Infection

    • Recruiting
    • Age: 18 years and older
    • Phase 3
    • Pill or oral medicine

    Phase III trial evaluating doravirine as an alternative to dolutegravir in treatment naïve people living with HIV-1 infection.

    Trial name
    ELDORADO (NCT06203132)
    Testing
    Doravirine + tenofovir DF + lamivudine, Dolutegravir + tenofovir DF + lamivudine or emtricitabine
    Where
    19 sites in Brazil, Cameroon and 4 more
    Volunteers
    610 people
    Sponsor
    ANRS, Emerging Infectious Diseases
    Can I take part? ELDORADO
  • Alcohol Use Disorder, Alcohol-Related Injury

    Preventing Harmful Alcohol Use Among Trauma Patients in Cameroon

    • Not yet recruiting
    • Age: 18 years and older
    • Lifestyle or therapy programme

    Brief Summary Alcohol use is a major contributor to injury burden in Cameroon, particularly among trauma patients presenting to emergency departments.

    Conditions
    Alcohol Use Disorder, Alcohol-Related Injury, Trauma
    Trial name
    NCT07677449
    Testing
    Cameroon-Adapted SBIRT, Usual Care
    Where
    Cameroon
    Volunteers
    690 people
    Sponsor
    University of Buea
    Can I take part? NCT07677449
  • Chronic Respiratory Conditions

    Pulmonary Rehabilitation in African Countries

    • Not yet recruiting
    • Age: 18 years and older

    Chronic Respiratory Diseases (CRDs) are common disabling conditions worldwide with high prevalence, morbidity and mortality. More than half of the CRD patients live in low- and middle-income countries (LMICs) where resources for…

    Trial name
    NCT07602673
    Testing
    Centre-based Pulmonary Rehabilitation, Community-based Pulmonary Rehabilitation
    Where
    3 sites in Cameroon, Nigeria and 1 more
    Volunteers
    150 people
    Sponsor
    University of Edinburgh
    Can I take part? NCT07602673
  • Trauma, Injury

    Data-Driven Lay First Responder Program in Cameroon

    • Not yet recruiting
    • Age: All ages
    • Lifestyle or therapy programme

    Cameroon experiences a high burden of injury-related morbidity and mortality and currently lacks a formal pre-hospital care system.

    Trial name
    K-LFR Project (NCT07581327)
    Testing
    Lay First Responder (LFR) training
    Where
    Cameroon
    Volunteers
    1,812 people
    Sponsor
    Sabrinah Christie
  • Human Papillomavirus Infection, Cervical Intraepithelial Neoplasia Grade 2 (CIN2)

    Digital Telecytology for Triage of HPV-Positive Women in Cameroon

    • Recruiting
    • Age: 25 to 50 years
    • Surgery or procedure

    This study evaluates the diagnostic accuracy and feasibility of a same-day cervical cancer screening strategy using HPV self-sampling followed by digital telecytology triage among HPV-positive women in Cameroon.

    Conditions
    Human Papillomavirus Infection, Cervical Intraepithelial Neoplasia Grade 2 (CIN2), Cervical Cancer Screening Methods
    Trial name
    NCT07550010
    Testing
    HPV testing (self-sampling), Digital telecytology, AI-assisted telecytology
    Where
    2 sites in Cameroon
    Volunteers
    1,800 people, healthy volunteers welcome
    Sponsor
    University Hospital, Geneva
    Can I take part? NCT07550010
  • Effects of Menstrual Products on the Vaginal Microbiome

    Improving Menstrual and VAginal Health for All

    • Recruiting
    • Age: 18 to 35 years

    A three-period crossover trial will study the effects of short-term use of 3 menstrual products (menstrual pad, tampon, menstrual cup) on the bacterial composition of the vaginal microbiome in three countries (Peru, Cameroon, and…

    Trial name
    IMVAHA (NCT06646185)
    Testing
    Menstrual Pads, Menstrual Cups, Tampons
    Where
    3 sites in Cameroon, Peru and 1 more
    Volunteers
    100 people, healthy volunteers welcome
    Sponsor
    Swiss Tropical & Public Health Institute
    Can I take part? IMVAHA
  • Cervical Cancer Screening, HIV

    Optimization of Cervical Cancer Screening Strategies Among Women Living With HIV: Effectiveness and Implementation of Decentralized Approach Using a Mobile Team With HPV Testing in the Western Region of Cameroon

    • Recruiting
    • Age: 25 to 49 years

    Context. Cervical cancer (CC) is a leading cause of death among women living with HIV (WLHIV) in resource-limited settings. Yet, effective methods for screening and preventing CC are available.

    Trial name
    OptiTri_MT (NCT07181278)
    Testing
    Mobile unit with quasi point of care HPV testing and immediate triage + treatment, Centralized screening
    Where
    6 sites in Cameroon
    Volunteers
    1,180 people
    Sponsor
    Institut de Recherche pour le Developpement
    Can I take part? OptiTri_MT
  • Cardiac Disease, Metabolic Disease

    Cardiometabolic Disease Risk Factors in Cameroon

    • Enrolling by invitation
    • Age: 18 years and older
    • Observational study

    Cardiometabolic diseases (CMDs) are a major public health concern in sub-Saharan Africa, including Cameroon. Studies have shown a significant increase in the prevalence of hypertension, diabetes, and obesity in recent years.

    Trial name
    URBACAM-D (NCT06957548)
    Testing
    Cardiometabolic disease
    Where
    Cameroon
    Volunteers
    200 people, healthy volunteers welcome
    Sponsor
    Johns Hopkins University
    Can I take part? URBACAM-D

Completed, with results posted

All –
  • Trauma/Injury Problem

    Pre and Post-Implementation of Injury/Trauma First Aid Training Among Early Secondary School Students in Fako, Cameroon

    • Completed
    • Age: 10 to 65 years
    • Results posted

    To save lives, alleviate pain, and prevent injuries from worsening before medical assistance can be summoned, first aid is essential. These fundamental skills are accessible to everyone, including young people.

    Trial name
    NCT07110077
    Testing
    Young First Aiders Traing of Early Secondry School children
    Where
    Cameroon
    Volunteers
    166 people, healthy volunteers welcome
    Sponsor
    University of Buea
    Can I take part? NCT07110077
  • Yaws

    Evaluation of a LAMP Assay for T. Pallidum. Pertenue

    • Completed
    • Age: All ages
    • Observational study
    • Results posted

    This is a diagnostic evaluation comparing the performance of real-time PCR performed at a national reference laboratory and a LAMP assay performed at a regional hospital for the diagnosis of yaws

    Trial name
    LAMP4YAWS (NCT04753788)
    Testing
    PCR, LAMP
    Where
    3 sites in Cameroon, Côte d’Ivoire and 1 more
    Volunteers
    563 people
    Sponsor
    London School of Hygiene and Tropical Medicine
    Can I take part? LAMP4YAWS
  • Wounds and Injury

    Mobile Phone-administered Triage Tool to Followup on Discharged Trauma Patients

    • Completed
    • Age: All ages
    • Results posted

    After being admitted to and then discharged from a hospital in Cameroon for having experienced an injury, there is no established way for the health system to check in on how the discharged person is doing.

    Trial name
    NCT03805646
    Testing
    Mobile Phone-based Triage Tool
    Where
    4 sites in Cameroon
    Volunteers
    3,990 people, healthy volunteers welcome
    Sponsor
    University of California, Los Angeles
    Can I take part? NCT03805646
  • Tuberculosis, Pediatric

    TB Innovation Project: A Pre- and Post- Implementation Assessment (TIPPI)

    • Completed
    • Age: Up to 14 years
    • Observational study
    • Results posted

    This evaluation will be conducted in ten countries involved in the Catalyzing Pediatric TB Innovation (CaP-TB) project: Cameroon, Cote D'Ivoire, Democratic Republic of Congo, Kenya, Lesotho, Malawi, Tanzania, Uganda, Zimbabwe and…

    Trial name
    TIPPI (NCT03948698)
    Testing
    Innovative approached to pediatric TB care
    Where
    10 sites in Cameroon, Côte d’Ivoire and 8 more
    Volunteers
    4,159,533 people
    Sponsor
    Elizabeth Glaser Pediatric AIDS Foundation
    Can I take part? TIPPI
  • Loiasis

    Loiasis Cross-reactive Antigenemia and Treatment-related Adverse Events

    • Completed
    • Age: 18 years and older
    • Phase 4
    • Pill or oral medicine
    • Results posted

    This study seeks to determine which Loa loa antigens are released into circulation when infected individuals are treated with ivermectin.

    Trial name
    NCT05085665
    Testing
    Ivermectin
    Where
    Cameroon
    Volunteers
    41 people, healthy volunteers welcome
    Sponsor
    Washington University School of Medicine
    Can I take part? NCT05085665

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