Clinical trials: sponsored by University of British Columbia
Knee Osteoarthritis
Pain Informed Movement for People With Knee Osteoarthritis
The goal of this clinical trial is to compare a pain informed movement program to standard neuromuscular exercise in people with knee osteoarthritis. The main question it aims to answer are: 1.
- Trial name
- NCT05730829
- Testing
- pain informed movement, standard neuromuscular exercise, Pain Neuroscience Education (PNE)
- Where
- Canada
- Volunteers
- 69 people
- Sponsor
- McMaster University
Hip Osteoarthritis
Feasibility of the Hip Instructional Prehabilitation Program for Enhanced Recovery (HIPPER)
Osteoarthritis (OA), leading to hip replacement, is a leading contributor to global mobility impairment. Given the boom in the older demographic it is not surprising that there is an 11% increased demand for replacement every 5…
- Trial name
- HIPPER (NCT02969512)
- Testing
- HIPPER, OASIS Online Educational Webinars
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- University of British Columbia
Atopic Dermatitis, Skin Diseases
BROadband vs Narrowband photoTherapy for Eczema Trial Nested in the CACTI Cohort
Atopic dermatitis (eczema) is a complicated skin condition. In fact, it represents many different underlying problems. These include abnormalities in the skin barrier, the immune system and the ability to handle different…
- Conditions
- Atopic Dermatitis, Skin Diseases, Eczema
- Trial name
- BRONTE (NCT04818138)
- Testing
- Narrowband UVB phototherapy, Broadband UVB phototherapy
- Where
- Canada
- Volunteers
- 69 people
- Sponsor
- Women's College Hospital
Joint Disease, Rheumatoid Arthritis
an On-demand Program to EmpoweR Active Self-management (OPERAS)
Self-management is a key component of successful chronic disease management and patients can benefit from learning about how daily activities and treatments relate to their symptoms and health status on an ongoing basis.
- Trial name
- OPERAS (NCT03404245)
- Testing
- Education, Fitbit/self-management app, physiotherapist counselling., Same intervention with a 6 month delay
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- University of British Columbia
Melanoma
Measuring Real Time Decision-Making About Ultraviolet Radiation (UVR) Protection
The purpose of this study is to understand how people make decisions about sun protection. This study is important in helping to protect against sun exposure, since it is a main risk factor for melanoma.
- Trial name
- NCT01004952
- Testing
- screening questionnaire
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Joint Diseases, Knee Osteoarthritis
SuPRA: Using Wearable Activity Trackers With a New Application to Improve Physical Activity in Knee Osteoarthritis
Physical activity is an essential first-line treatment for patients with knee osteoarthritis (OA). However, only 13% of patients meet the activity recommendation of 150 minutes or more per week.
- Trial name
- NCT02585323
- Testing
- Education session, Fitbit/FitViz, PT counselling, Same intervention with a 3 month delay
- Where
- 2 sites in Canada
- Volunteers
- 51 people
- Sponsor
- University of British Columbia
Ketosis, Type 2 Diabetes
Exogenous Ketones in Type 2 Diabetes
Exogenous ketone supplements are proposed to have glucose-lowering potential, provide an alternative fuel for the brain and to enhance cognitive function.
- Trial name
- NCT04194450
- Testing
- Ketone monoester
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- University of British Columbia
Hypertrophic Cardiomyopathy, Sudden Cardiac Death
PRecIsion Medicine in CardiomyopathY
This is a retrospective cohort study of pediatric hypertrophic cardiomyopathy (HCM) patients using chart and registry review methodology.
- Trial name
- PRIMaCY (NCT04036799)
- Volunteers
- 572 people
- Sponsor
- The Hospital for Sick Children
Bipolar I Disorder
Mood Stabilizer (MS)+ Antidepressant vs MS + Placebo in Maintenance of Bipolar Disorder.
Patients with bipolar I disorder (BD) experience depression 3 times more frequently than mania, and antidepressants are prescribed as adjuncts to mood stabilizers in up to 70% of patients.
- Trial name
- NCT00958633
- Testing
- Escitalopram, Bupropion XL
- Where
- Canada
- Volunteers
- 237 people
- Sponsor
- University of British Columbia
Sepsis, Infection
Paediatric Rapid Sepsis Trigger (PRST) Tool
Sepsis is the leading cause of death and disability in children, every hour of delay in treatment is associated with greater organ damage and ultimately death.
- Trial name
- PRST (NCT04304235)
- Testing
- Pediatric Rapid Sepsis Trigger (PRST) tool, Emergency Triage and Treatment (ETAT) guidelines
- Where
- 3 sites in Kenya, Uganda
- Volunteers
- 18,693 people
- Sponsor
- University of British Columbia
Diabetes, Lipohypertrophy
Ultrasound Detection and Characterization of Subclinical Hypertrophy in Diabetes
This is a pilot study to enroll 100 people to assess the incidence of lipohypertrophy as detected with ultrasound and its impact on glycemic variability.
- Trial name
- NCT02348099
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Elevated Blood Sugar
Power of Choice on Autonomy, Motivation, Exercise Adherence, and Cardiorespiratory Fitness
People with elevated blood sugar levels are at increased risk of developing chronic medical conditions such as obesity, type 2 diabetes, and cardiovascular disease.
- Trial name
- NCT03576924
- Testing
- MICT, HIIT, CHOICE
- Where
- Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Ozone Exposure During Rest and Exercise
Susceptibility of Cardiorespiratory Responses to Ozone During Cycling Exercise
Ground level ozone (O3) is a common airborne pollutant that is well recognized to cause negative respiratory symptoms and impair pulmonary function.
- Trial name
- NCT05473000
- Testing
- Exercise, Ozone, Room air
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Maternal Sepsis, Neonatal Sepsis
Smart Discharges for Mom & Baby
This study aims to build a predictive algorithm that identifies mother-newborn dyads most at risk of death or complications in the 6 weeks after birth.
- Trial name
- NCT05730387
- Testing
- Observational only
- Where
- Canada
- Volunteers
- 7,182 people
- Sponsor
- University of British Columbia
Sacroiliac Strain, Low Back Pain
Correction of Low Back Pain From Sacroiliac Malrotation With a Simple in Home Exercise
60 participants with low back pain will be examined to determine the direction and extent of sacroiliac malrotation. If malrotation exists, they will be randomized to 3 treatment groups: 1 will be taught how to use their thigh to…
- Trial name
- SIbackpain (NCT03888235)
- Testing
- Immediate corrective exercises, Immediate use of pelvic support belt, Delayed treatment
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy
Efficacy of Movement Breaks in Real-World Settings
The purpose of this study is to determine the efficacy of performing "exercise snacks" (short movement breaks throughout the day) on various measures of cardiometabolic health.
- Trial name
- NCT05574426
- Testing
- Movement Breaks
- Where
- 2 sites in Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Chronic Pain, Cancer
Immersive Multimedia as an Adjunctive Measure for Pain Control in Cancer Patients
This study seeks to explore the efficacy of immersive multimedia experiences as a practical adjunctive therapeutic intervention in the self-management of the chronic pain associated with cancer patients.
- Trial name
- NCT02995434
- Testing
- Virtual Reality Headset, 2D PC
- Where
- 3 sites in Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Asthma and/or Exercise Induced Bronchoconstriction, Ozone Air Pollution
Salbutamol Use in Ozone Air Pollution by People With Asthma and/or Exercise Induced Bronchoconstriction (EIB)
Salbutamol use is increased in areas with high levels of ozone pollution and the potential consequences of this are not well known.
- Trial name
- NCT05087693
- Testing
- Salbutamol, Ozone, Filtered Air
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University of British Columbia
Type 2 Diabetes, Type 1 Diabetes
Dark Chocolate and Glucose Levels in Diabetes
Diabetes is a growing concern in the world with an estimated 9.3% of adults, ages 20-79, with it in 2019, type 2 diabetes accounting for 90% of this total.
- Trial name
- NCT04847999
- Testing
- Dark chocolate
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of British Columbia
Bipolar Depression
Efficacy of rTMS in Bipolar Depression
Bipolar Disorder is a common condition that is characterized by periods of mood elevation however periods of chronic and recurring depressive episodes are more common and can be severely disabling.
- Trial name
- rTMS-BD (NCT02749006)
- Testing
- iTBS repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- 2 sites in Canada
- Volunteers
- 37 people
- Sponsor
- University of British Columbia