Clinical trials: suspended
Stroke
Crossmodal Learning in Therapeutic Processes (Task 2-1)
Interventional study of the effects of vibro-tactile feedback on behavioral deficits and learning during motor training in patients with stroke.
- Trial name
- NCT05262699
- Testing
- Vibro-tactile stimulation
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Pregnancy Complications
The ADRB3 Receptor in Pregnancy
The primary overall objective of this study is to characterize the levels of and compare levels of the ADRB3 receptor in human non-pregnant myometrium, pregnant myometrium at different time points in pregnancy, in normal and…
- Trial name
- NCT02381106
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Glioblastoma
Early Stereotactic Gamma Knife Radiosurgery to Residual Tumor After Surgery of Newly Diagnosed Glioblastoma
Gamma GBM is a single-arm phase II trial that prospectively measures the progression-free survival time after addition of an early gamma knife boost to areas of residual tumor to standard-of-care (surgery, chemo-radiotherapy…
- Trial name
- Gamma-GBM (NCT03055208)
- Testing
- gamma knife radiosurgery (15 Gy to 50% isodose)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Universitätsmedizin Mannheim
Chronic Pain
Intraoperative Ketamine on Chronic Pain After Mastectomy
Preventive analgesia is when an administered analgesic drug provides reduction in pain beyond its duration of action. This can be used to reduce acute postoperative pain and prevent occurrence of chronic post-surgical pain.
- Trial name
- NCT02729805
- Testing
- Saline, Ketamine 0.5mg/kg, Ketamine 0.75mg/kg
- Where
- Hong Kong
- Volunteers
- 135 people
- Sponsor
- The University of Hong Kong
Neuropathic Pain
Evaluation of the Safety and Efficacy of N-desmethylclobazam in Patients With Peripheral Neuropathic Pain
Neuropathic pain (NP) affects up to 8% of the general population and its successful management is an unmet medical need. Half of the patients report inadequate response to therapy and unwanted side effects such as sedation and…
- Trial name
- NDMC-201 (NCT04480164)
- Testing
- NDMC
- Where
- Switzerland
- Volunteers
- 76 people
- Sponsor
- Besson Marie
Stroke
Noninvasive Brain Stimulation for Stroke
Noninvasive brain stimulations will be used in acute and chronic stroke patients to improve a variety of functions.
- Trial name
- NIBSstroke (NCT01503073)
- Testing
- tdcs (ELDITH, Neuroconn, Ilmenau, Germany)
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Stroke, Hemiparesis
Post Stroke Motor Learning
Noninvasive brain stimulations (NIBS) will be used in chronic stroke patients to improve motor learning. Functional magnetic resonance imaging will be used to evaluate the mechanisms underlying motor learning in healthy…
- Trial name
- NCT01519843
- Testing
- transcranial direct current stimulation tDCS, transcranial magnetic stimulation TMS
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Dental Caries
Efficacy of Two Protocols for Applying Fluorine Varnish to Deciduous Teeth
Evidence that the data flow analysis tests, there are still no studies that show the clarity of the protocols of its application, including the interval and execution factors of applications, concentration of fluoridation and…
- Trial name
- CEPECO3 (NCT03827889)
- Testing
- WMP of fluoride varnish, TWLP of fluoride varnish, DHP (educational intervention)
- Where
- Brazil
- Volunteers
- 168 people
- Sponsor
- Universidade Ibirapuera
Ptsd
PTSD Interview Regarding Future Study Design and Equipment.
To gain insight and perspective unique to individuals with a diagnosis of PTSD, this study will utilize an experiential one-to-one interview format.
- Trial name
- NCT05276115
- Testing
- Interview
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Life University
Hypertension
Autonomic Nervous System Function - Hypertension
The Life University Center for Chiropractic Research is conducting a research study to better understand the physiological differences, in terms of Autonomic nervous system function, between individuals with Hypertension and…
- Trial name
- NCT05312996
- Testing
- Heart Rate Variability, Galvanic Skin Response (Biopac)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Life University
Stress
Upper Cervical and Thoracic Chiropractic Adjustment
The proposed study examines the differences in how the ANS responds to cervical adjustments in comparison to thoracic adjustments.
- Trial name
- NCT05465395
- Testing
- Upper Cervical Adjustemnt, Thoracic Adjustemnt
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Life University
Hypertension
Telehealth Referral to Improve Outcomes
Emergency patients often have uncontrolled asymptomatic hypertension upon discharge from the emergency department. This 3-arm randomized controlled trial will evaluate the impact of nurse telehealth encounters and remote patient…
- Trial name
- TRIO (NCT05000970)
- Testing
- blood pressure cuff PLUS tablet, Telehealth Consult
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Triple-Negative Breast Cancer
A Trial Evaluating the Efficacy and Safety of EndoTAG®-1 in Combination With Paclitaxel and Gemcitabine Compared With Paclitaxel and Gemcitabine as First-line Therapy in Patients With Visceral Metastatic Triple-negative Breast Cancer
This is a prospective, multicenter, open-label, randomized, and controlled trial to test the superiority of EndoTAG®-1 in combination with paclitaxel and gemcitabine versus paclitaxel in combination with gemcitabine.
- Trial name
- NCT03002103
- Testing
- EndoTAG-1, Paclitaxel, Gemcitabine Hydrochloride
- Where
- 6 sites in Taiwan
- Volunteers
- 420 people
- Sponsor
- SynCore Biotechnology Co., Ltd.
REM Sleep Behavior Disorder
Effects of Tablet Computer-based Cognitive Training in Patients With Idiopathic REM Sleep Behavior Disorder
To evaluate the effectiveness of tablet computer-based cognitive training in patients with idiopathic REM sleep behavior disorder.
- Trial name
- NCT05256836
- Testing
- Tablet computer-based cognitive training program
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
HER-2 Gene Amplification, HER2-positive Gastric Cancer
Safety and Activity Study of HER2-Targeted Dual Switch CAR-T Cells (BPX-603) in Subjects With HER2-Positive Solid Tumors
This is a Phase 1/2, open-label, multicenter, non-randomized study to investigate the safety, tolerability, and clinical activity of HER2-specific dual-switch CAR-T cells, BPX-603, administered with rimiducid to subjects with…
- Conditions
- HER-2 Gene Amplification, HER2-positive Gastric Cancer, HER2-positive Breast Cancer, HER-2 Protein Overexpression
- Trial name
- NCT04650451
- Testing
- chimeric antigen receptor (CAR) T cell therapy
- Where
- 7 sites in United States
- Volunteers
- 220 people
- Sponsor
- Bellicum Pharmaceuticals
Septic Shock
Extracorporal Cytokin Removal in Septic Shock: a Prospective, Randomized, Multicenter Clinical Trial
Sepsis and septic shock have mortality rates between 20-50%. When standard therapeutic measures fail to improve patients' condition, additional therapeutic alternatives are applied to reduce morbidity and mortality.
- Trial name
- DECRISS (NCT04742764)
- Testing
- Standard medical therapy, Standard medical therapy plus cytokine removal treatment using Cytosorb, with the adsorber changed in every 12 hours, Standard medical therapy plus cytokine removal treatment using Cytosorb, with the adsorber changed in every 24 hours
- Where
- Hungary
- Volunteers
- 135 people
- Sponsor
- University of Pecs
Gastrointestinal Cancer
Patient Reported Scale vs CTCAE Grading: A Prospective Comparator Study
Over a million new cancer cases are diagnosed in India each year. This huge burden coupled with inadequate infrastructural facilities is adversely affecting the quality of patient care.
- Trial name
- PROSE (NCT05158907)
- Testing
- Patient reported Adverse event scale
- Where
- India
- Volunteers
- 220 people
- Sponsor
- Tata Medical Center
Diabetes, Diabetic Foot
Foot Assessment in People With Diabetes: A Quantitative Diagnostic Approach
This observational cohort study aims to develop a novel risk stratification system implementing biomechanics to aid in the prevention of diabetic foot ulcers.
- Conditions
- Diabetes, Diabetic Foot, Diabetes Complications, Diabetes; Neuropathic (Manifestation)
- Trial name
- NCT03089463
- Testing
- Observation
- Where
- United Kingdom
- Volunteers
- 153 people
- Sponsor
- Staffordshire University
Schizophrenia
Clinical Intervention on Cognitive Impairment of Schizophrenia With Metabolic Syndrome
This is a single-center, randomized, parallel-control study conducted in schizophrenic inpatients with metabolic syndrome who have been conducted with olanzapine.
- Trial name
- NCT04518319
- Testing
- Omega-3 polyunsaturated fatty acids, Xbox aerobic exercise, transcranial direct current stimulation,tDCS
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Mental Health Center
Glaucoma
Impact of an Educational Video on Satisfaction After Glaucoma Surgery
Overall Objective: This study will assess whether an educational video is effective in increasing patient satisfaction with glaucoma surgery. 1.
- Trial name
- NCT03958929
- Testing
- Educational Video
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Sun Yat-sen University