Clinical trials: suspended
Chronic Widespread Pain
Fecal Microbiota Transplantation for Patients With Chronic Widespread Pain
This study aims to explore the effect of Fecal Microbiota Transplantation (FMT) on the clinical symptomatology in Chronic Widespread Pain (CWP), to assess the acceptability, tolerability, and safety of FMT in patients with CWP…
- Trial name
- NCT05700331
- Testing
- Fecal Microbiota Transplantation, Sigmoidoscopy
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Pollution; Exposure, Smoke Inhalation
Controlled Exposure of Healthy Nonsmokers to Secondhand and Thirdhand Cigarette Smoke
This study compares the health effects of dermal and inhalational exposure to thirdhand cigarette smoke to those of inhalational exposure to secondhand cigarette smoke in healthy, adult nonsmokers.
- Conditions
- Pollution; Exposure, Smoke Inhalation, Exposure to Pollution
- Trial name
- THS04 (NCT04013256)
- Testing
- Cigarette Smoke
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Influenza
Clinical Trial of Efficacy and Safety of ММН-407 in the Treatment of Influenza in Outpatient Adults
The main purpose of this study is: to evaluate the efficacy and safety of MMH-407 in the treatment of influenza in outpatient adults.
- Trial name
- NCT04250311
- Testing
- MMH-407
- Where
- 20 sites in Russia
- Volunteers
- 314 people
- Sponsor
- Materia Medica Holding
Dystonia
Effect of Increasing Motor Cortex Inhibition on Task Specific Dystonia
Dystonia is a disease where muscles in the affected body part are abnormally active. This may result in abnormal postures. The underlying mechanisms are not known.
- Trial name
- NCT01823237
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Emory University
Aortic Valve Regurgitation Acquired
Aortic Valve Regurgitation Acquired After Left Ventricular Assist Device Implantation: an Outstanding in Vivo Model of Valvular Heart Diseases
To investigate histological structure and molecular changes involved on the onset of AVD after left ventricular assist device (LVAD) implantation and to compare them with those of patients operated on for severe aortic…
- Trial name
- NCT03279029
- Testing
- blood samples, biopsy
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Chronic Pain, Anxiety
Phase II Trial of Nu-V3 Non-Invasive Nerve Stimulation Device for Chronic Pain, Anxiety, Depression, Sleeplessness
This Nu-V3 clinical study is a randomized, phase II, open-label study evaluating the Nu-V3 cranial nerve stimulation treatment device in patients with chronic pain, anxiety, depression, and/or sleeplessness.
- Conditions
- Chronic Pain, Anxiety, Depression, Sleeplessness
- Trial name
- Nu-V3P2RCT (NCT05394545)
- Testing
- Nu-V3
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nu-Life Solutions
Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
Evaluation of IBI302 Injection in nAMD or DME
The purpose of this study is to determine the efficacy and safety of intravitreal IBI302 in the treatment of subjects with neovascular age-related macular degeneration (only in Phase I) or diabetic macular edema.
- Trial name
- NCT05961007
- Testing
- Intravitreal injection of IBI302(dose 1), Intravitreal injection of IBI302(dose 2), Intravitreal injection of IBI302(dose 3)
- Where
- China
- Volunteers
- 234 people
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Self Confidence
Pandemic and Gynecological Surgery Education
SarsCov2/COVID19 virus emerged in Wuhan, China in December 2019, and cases were seen in our country about 3 months later, causing a worldwide pandemic.
- Trial name
- NCT05143749
- Testing
- video tutorial
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Osteoarthritis
Effect of Natural Senolytic Agents & NLRP3 Inhibitors on Osteoarthritis
Objective: To determine the efficacy of natural senolytic agents and NLRP3 Inflammasome inhibitors for reducing knee symptoms and effusion-synovitis in patients with symptomatic knee osteoarthritis and knee effusion-synovitis.
- Trial name
- NCT05276895
- Testing
- Quercetin and Fisetin tab., Quercetin Cap/Tab,Fisetin Cap/tab and Glycyrrhizin capsules
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Acute Lymphoblastic Leukemia (ALL), Non Hodgkin Lymphoma (NHL)
Safety and Efficacy Evaluation of CD19-UCART
The purpose of this study is to evaluate the safety and efficacy of ascending doses of CD19-UCART in patients with relapsed or refractory B-cell hematological malignancies.
- Trial name
- NCT03229876
- Testing
- CD19-UCART
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- Bioray Laboratories
Coronary Artery Disease, Percutaneous Coronary Intervention
Thrombus Aspiration in Heavy Thrombus Burden Acute ST-elevation Myocardial Infarction
Recent guidelines for the management of ST-elevation myocardial infarction (STEMI) recommend against the routine use of thrombus aspiration (TA) during primary percutaneous coronary intervention (PPCI) (Class III indication).
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, ST Elevation Myocardial Infarction
- Trial name
- TSUNAMI (NCT04912570)
- Testing
- Manual Thrombus Aspiration, Standard PCI
- Where
- 4 sites in Egypt
- Volunteers
- 124 people
- Sponsor
- The Young Investigator Group of Cardiovascular Research
Physical Inactivity
Parent-Based Physical Activity Intervention for Black Families
This study is an 8-week parent-based physical activity intervention focusing on increasing physical activity in preschool-aged children. The participants will be randomized into two groups: control and intervention.
- Trial name
- NCT05910671
- Testing
- Physical Activity Phone Calls and Notebook
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Colorectal Neoplasms
Biomarkers for Apatinib and Bevacizumab in Second-line Therapy for Colorectal Cancer(BABST-C)
Bevacizumab, an antibody against vascular endothelial generated factor (VEGF), combined with the fluorouracil-based chemotherapy regimens has been approved in the 1st and 2nd line treatments for metastatic colorectal…
- Trial name
- BABST-C (NCT03743428)
- Testing
- Apatinib Mesylate Tablets, Bevacizumab Injection
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shenzhen People's Hospital
Critical Limb Ischemia
Stellarex DCB Versus Standard Balloon Angioplasty for Treatment of Below-The-Knee (BTK) Arteries
The purpose is to demonstrate the safety and effectiveness of the Stellarex DCB for the treatment of stenosis or occlusions of below-the-knee arteries.
- Trial name
- ILLUMENATE-BTK (NCT03175744)
- Testing
- Stellarex DCB, PTA Catheter
- Where
- 21 sites in United States, Australia and 3 more
- Volunteers
- 82 people
- Sponsor
- Spectranetics Corporation
Fertility Preservation
Ovarian Tissue Cryopreservation for Fertility Preservation in Girls and Women
This study will compare efficacy of ovarian tissue freezing using slow-freeze versus vitrification methods.
- Trial name
- NCT05434936
- Testing
- Oophorectomy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Baylor College of Medicine
Physical Inactivity, Obesity, Childhood
Effectiveness of a Telehealth-based Physical Activity Intervention
This study is a 11 week telehealth intervention focusing on increasing physical activity in adolescents who are receiving medical care for obesity. The participants will be randomized into two groups: control and intervention.
- Trial name
- NCT05123235
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Perineal Tear
Low Power Laser for Spontaneous Perineal Laceration
Scenario: spontaneous perineal laceration is an injury to the tissue in the perineum region, which can occur during vaginal delivery.
- Trial name
- LASER (NCT04914182)
- Testing
- LASER, CONTROL
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Electrical Stimulation
Neuromuscular Adaptations After Training in the Muscle Belly of Triceps Surae
This study aims to evaluate on an acute session of the central and peripheral contributions of electrical stimulation on the muscle belly of the triceps surae, electrical stimulation of the tibial nerve and voluntary exercise of…
- Trial name
- NCT03905772
- Testing
- Voluntary exercise, Wide pulse responder group, Wide pulse non responder group
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Hip Osteoarthritis, Chronic Pain
Comparative Study Between Steroid Plus Anesthetic Block and CRF in Participants With Hip Osteoarthritis
This will be a prospective, multi-center, double-blinded, randomized study designed to compare the efficacy of Conventional Radiofrequency (CRF) and the anesthetic block of the anterior sensory branches to the hip to control pain…
- Trial name
- NCT04876859
- Testing
- CRF of anterior sensitive branches to the hip, Anesthetic block with steroid injection of anterior sensitive branches to the hip
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- University of Brasilia
Head and Neck Cancer
MRG FU With Radiotherapy for Palliation of H&N Cancer
Head and neck cancer is the sixth most common form of malignancy world-wide. Surgery, chemotherapy and radiation are associated with a high burden of side effects; tumour recurrence within the neck continues to be a major cause…
- Trial name
- NCT03218475
- Testing
- MR Guided Focused Ultrasound
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre