Clinical trials: Phase not applicable
Prostate Cancer
Rectal Spacer for Prostate Cancer Radiation Image Guidance
The purpose of the study is to determine if a radiopaque hydrogel rectal spacer, SpaceOAR Vue®, can be used in place of fiducial markers when aligning patients for radiotherapy.
- Trial name
- NCT05650021
- Testing
- SpaceOAR Vue
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Milton S. Hershey Medical Center
Chronic Pain, Musculoskeletal Pain
Multicomponent Exercise and Pain Science Education for Fall Prevention in Older Adults With Chronic Musculoskeletal Pain (MovePainFall)
Chronic musculoskeletal pain is common in older adults and is associated with reduced mobility, loss of function, poorer quality of life, fear of movement, fear of falling and a higher risk of falls.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Accidental Falls, Fear of Falling
- Trial name
- MovePainFall (NCT07889024)
- Testing
- MovePainFall multicomponent exercise programme, Pain science and fall-prevention education
- Where
- Portugal
- Volunteers
- 40 people
- Sponsor
- Instituto Politécnico de Bragança
Cystic Fibrosis (CF), Cystic Fibrosis - Complete
OnTrackCF: Engagement, Feasibility, and Acceptability Study
This is a multi-site, nonrandomized study using mixed methods approach to evaluate the feasibility, acceptability, and user engagement of OnTrackCF for adults with Cystic Fibrosis (AWCF).
- Trial name
- OnTrackCF (NCT07031323)
- Testing
- OnTrackCF
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Boston Children's Hospital
Obsessive-Compulsive Disorder (OCD), Transcranial Magnetic Stimulation
Continuous Theta-Burst Stimulation for Obsessive-Compulsive Disorder: An Open-Label Study
This single-arm, open-label study evaluates short-term symptom improvement and tolerability of continuous theta-burst stimulation (cTBS), a non-invasive brain stimulation technique, in adults with obsessive-compulsive disorder…
- Conditions
- Obsessive-Compulsive Disorder (OCD), Transcranial Magnetic Stimulation, Electroencephalography
- Trial name
- NCT07896837
- Testing
- Continuous Theta-Burst Stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
End Stage Renal Disease
Post Market Study for VasQ, an External Support Implant for Arteriovenous Fistula
VasQ is an external support implant for arteriovenous fistulas created for dialysis access. This is a postmarket surveillance, prospective, multi-center, randomized, controlled, open label trial enrolling 300 patients randomized…
- Trial name
- NCT06516653
- Testing
- VasQ, Arteriovenous fistula creation for dialysis vascular access
- Where
- 13 sites in United States
- Volunteers
- 300 people
- Sponsor
- Laminate Medical Technologies
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8
Improving Patient-Centered Communication in Breast Cancer Through Patient and Provider Interventions
This trial studies the effectiveness of two interventions on patient reported outcomes of patient centered communication and decision making about breast cancer treatment.
- Conditions
- Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8
- Trial name
- SHARES (NCT04549571)
- Testing
- Decision Aid iCanDecide - ESE website, Decision Aid iCanDecide - S website, Therapeutic Conventional Surgery
- Where
- 27 sites in United States
- Volunteers
- 614 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Coronary Artery Disease (CAD)
TRADENT Scoring Balloon Versus Non-scoring Balloon for Lesion Preparation in DCB-Based Coronary Intervention
This study will compare the effectiveness of the TRADENT™ coronary scoring balloon with a conventional non-scoring balloon for lesion preparation in patients undergoing a drug-coated balloon (DCB)-first percutaneous coronary…
- Trial name
- TRAD-PREP (NCT07899021)
- Testing
- TRADENT Scoring Balloon, Conventional Non-Scoring Coronary Balloon
- Volunteers
- 580 people
- Sponsor
- Ulsan University Hospital
Acute Respiratory Failure (ARF), Nitric Oxide
Modified Inhaled Nitric Oxide in Ventilated Patients With Acute Respiratory Failure
Pneumonia is the main cause of ICU admission in patients with acute respiratory failure (ARF). Severe pneumonia is a serious lung infection caused by bacteria, fungi, viruses, and other pathogens.
- Conditions
- Acute Respiratory Failure (ARF), Nitric Oxide, Pneumonia
- Trial name
- NCT07892001
- Testing
- Modified iNO
- Where
- China
- Volunteers
- 424 people
- Sponsor
- Southeast University, China
Duodenal Bleeding
Haemostatic Gel Prophylaxis for Post Duodenal Endoscopic Resection Bleeding
The purpose of this study is to test whether prophylactic application of haemostatic gel will reduce the rate of clinically significant bleeding requiring intervention (such as blood transfusion, admission to hospital, other…
- Trial name
- PURASTAT (NCT05746884)
- Testing
- duodenal mucosectomy, ampullectomy
- Where
- France
- Volunteers
- 67 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Leadless Pacemaker, Transthoracic Echocardiography
Ultrasound Guided Leadless Pacemaker Implantation
The leadless pacemaker is a novel pacing technology that has emerged in recent years. Compared with conventional lead pacemakers, its design avoids many complications associated with leads and pacemaker pockets, including lead…
- Trial name
- NCT07857330
- Testing
- Transthoracic echocardiography-guided, Conventional fluoroscopy-guided, Leadless pacemaker
- Volunteers
- 288 people
- Sponsor
- China National Center for Cardiovascular Diseases
Older Adults (50-90 Years), Depression
Integrating Depression Care Into HIV Services for Older People With HIV Using a Stepped Care, Task-Sharing Approach.
Depression levels will be compared using PHQ-9 in the Treatment as Usual arm(TAU) VS intervention arm to see if the stepped care intervention is effective in treating depression.
- Trial name
- NCT06894680
- Testing
- Stepped care, Treatment as usual
- Where
- Nigeria
- Volunteers
- 100 people
- Sponsor
- Royal Society of Tropical Medicine and Hygiene
Autism Spectrum Disorder
Effects of Mounted vs Unmounted Human-Equine Interaction on Autistic Youth
The goal of this clinical trial is to learn how interacting with horses affects autistic children and youth. The main questions it aims to answer are: How does interacting with horses affect cortisol, heart-rate variability, and…
- Trial name
- NCT07897123
- Testing
- Mounted Human-equine Interaction, Unmounted Human-equine Interaction, No-Horse Control
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Colorado State University
Acute Kidney Injury
Metabolic Complications Using a Low- Versus High Concentration Citrate Solution for Regional Anticoagulation in Continuous Kidney Replacement Therapy: A Pragmatic Randomized Trial.
This study is a pragmatic, randomized trial comparing two commercially available citrate solutions to determine their impact on metabolic complications in critically ill patients with acute kidney injury receiving continuous…
- Trial name
- LEON1 (NCT07751861)
- Testing
- low concentrated citrate solution (18 mmol/L), high concentrated citrate solution (136 mmol/L)
- Where
- Belgium
- Volunteers
- 176 people
- Sponsor
- University Hospital, Antwerp
Venous Ulcer of Leg
Dose-Response Structured Calf Muscle Pump Activation Strategies Versus Unsupervised Home Walks
investigates the comparative effectiveness of two interventions aimed at promoting the healing of venous leg ulcers-a common chronic condition characterized by impaired venous return and poor wound healing in the lower…
- Trial name
- Ulcer (NCT07763782)
- Testing
- Dose-Response Structured CMP Activation, Active Control
- Where
- Jordan
- Volunteers
- 80 people
- Sponsor
- MTI University
Lung Cancer, Exosomes
Molecular Profiling of Exosomes in Tumor-draining Vein of Early-staged Lung Cancer
This is an observational prospective single-center study of 30 patients operated for early-staged non-small cell lung cancer. The main aim is the analysis of molecular profiling of exosome with a sample in tumor-draining vein in…
- Conditions
- Lung Cancer, Exosomes, Non Small Cell Lung Cancer
- Trial name
- ExOnSite-Pro (NCT04939324)
- Testing
- Blood samples at 2 sites: peripheral vein and tumor-draining vein
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Limoges
Concussion (Diagnosis), Gait Abnormality
Supplementary Neuromuscular Rehabilitation During Acute Concussion Recovery
Approximately 1.6 to 3.8 million mild traumatic brain injuries, or concussions, occur yearly in the United States. Although most individuals progress through return-to-activity (RTA) using symptom-guided aerobic and functional…
- Trial name
- NCT07801482
- Testing
- Exercise, Return to Activity Progression
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northern Illinois University
Healthy Subjects
Functional Regulation of Autoreactive Lymphocytes: Phenotypic and Transcriptomic Investigations in Healthy Subjects
The goal of this study is to study the autoreactive lymphocytes in healthy volunteers. More specifically, this research aims to identify what distinguishes the autoreactive lymphocytes found in healthy individuals from those…
- Trial name
- REFLEX (NCT07898826)
- Testing
- Blood sampling at D0, Blood sampling at D0, M12 and M24
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Obesity & Overweight, Breast Cancer
Testing Health-Related Interventions: Voices of Equity Needed to Overcome Weight-bias in Obesity-Cancer Care
This study is testing an 8-week behavioral weight loss and wellness program adapted to the needs of Black/African American breast cancer survivors.
- Trial name
- THRIVE NOW (NCT07897890)
- Testing
- THRIVE NOW
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Indiana University
Esophageal Cancer, Colorectal (Colon or Rectal) Cancer
Quantitative Fluorescence Angiography With ICG for Perfusion Assessment During Surgery
The accurate assessment of intraoperative tissue perfusion is essential in any branch of surgery. Anastomotic leakage (AL) is one of the most feared complications following gastrointestinal surgery, with potentially threatening…
- Trial name
- SPY Q-ICG PAS (NCT05489757)
- Testing
- SPY Portable Handheld Imaging (SPY-PHI) System with SPY-QP Software
- Where
- Italy
- Volunteers
- 196 people
- Sponsor
- IRCCS San Raffaele
Lipodystrophy, Diabetes
Low Energy Diet and Familial Partial Lipodystrophy
To evaluate the therapeutic efficacy and metabolic impact of a low energy diet (LED) in people with familial partial lipodystrophy and diabetes.
- Conditions
- Lipodystrophy, Diabetes, Diet Modification
- Trial name
- NCT03900286
- Testing
- Total Dietary Replacement
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust