Clinical trials: enrolling by invitation
Right Heart Insufficiency, Tricuspid Regurgitation
Application of FAPI Visualization in the Assessment of Right Ventricular Dysfunction Due to Volume Overload
\"Bicuspid aortic stenosis represents the most prevalent form of cardiac valve disease, primarily resulting from degenerative alterations and rheumatic conditions that disrupt mitral valve function.
- Trial name
- NCT06663566
- Testing
- Diagnose the patients right heart function as well as right heart fibrosis, Diagnose the patient's right heart function as well as right heart fibrosis
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Beijing Anzhen Hospital
Transfusion Dependent Beta Thalassemia, Sickle Cell Disease
Decision-Making and Quality of Life Surrounding Hematologic Disease and Gene Therapy
Determine knowledge, attitudes, and beliefs among adult patients, and parents of pediatric patients, with transfusion dependent beta-thalassemia and sickle cell disease toward gene therapy to treat their or their child's illness…
- Trial name
- NCT06664541
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Georgetown University
Mitochondrial Diseases
Establishment of Reproductive Cohort and Prediction Model of Genetic Counseling for Mitochondrial Genetic Diseases
The goal of this observational study is to provide a reference for clinicians to conduct genetic counseling and carry out preimplantation genetic testing of mitochondrial patients.
- Trial name
- NCT06450964
- Testing
- Biological samples such as blood, urine, oral epithelial cells and nails of carriers were collected, and the mitochondrial DNA mutation heterogeneity level was determined.
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Anhui Medical University
Coronary Artery Bypass Graft CABG
Comparitive Effects of Elliptical Training vs Resistance Training on Cardiopulmonary Parameters in Post CABG Patients
COMPARATIVE EFFECTS OF ELLIPTICAL TRAINING VS RESISTANCE TRAINING ON CARDIOPULMONARY PARAMETERS IN POST CABG PATIENTS
- Trial name
- NCT06656117
- Testing
- Elliptical training, Resistance training
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Tooth Extraction
IMMEDIATE IMPLANT With Different Types of Membranes
forty patients will be selected from the outpatient's clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University for replacement of non-restorable tooth in posterior mandibular area.
- Trial name
- NCT06657651
- Testing
- immediate implant placement with dentin-derived membrane, immediate implant with extended platelet rich fibrin membrane
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Blau Syndrome
Efficacy and Safety of Tofacitinib in Refractory Blau Syndrome
This is a prospective cohort study to observe the efficacy and safety of Tofacitinib in children with Blau syndrome (BS). The investigators would analyze the rate of remission or low disease activity after treatment as well as…
- Trial name
- NCT06660329
- Testing
- Janus Kinase Inhibitor
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Mixed Hemorrhoids
The Effect of Methylene Blue Infiltrating Injection on Anal Pain After Milligan-Morgan Surgery: A Randomized Controlled Clinical Study
A variety of analgesic strategies are available following mixed hemorrhoids surgery, including pharmacological interventions (7), acupuncture, moxibustion, and electroacupuncture .
- Trial name
- MBI (NCT06660680)
- Testing
- Methylene Blue
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine
Osteoarthritis, Hand Osteoarthritis
Balneotherapy and Peloid Therapy Impact Small Joint Diseases
This clinical trial investigates the effects of natural healing factors (mineral water and mud procedures) in combination with regular rehabilitation of patients with degenerative small joint disease.
- Conditions
- Osteoarthritis, Hand Osteoarthritis, Foot Osteoarthritis
- Trial name
- NCT06477393
- Testing
- Regular rehababilitation, Heat procedures, Healing mud application
- Where
- 2 sites in Lithuania
- Volunteers
- 130 people
- Sponsor
- Lithuanian University of Health Sciences
Fibromyalgia (FM)
Effects of Immersive Virtual Reality in Fibromyalgia
Fibromyalgia is considered a disease of unknown etiology, which It affects between 2 to 5% of the population in developed countries, mostly women, diagnosed mainly between 40 and 50 years of age, and whose main characteristic is…
- Trial name
- NCT06658223
- Testing
- Exercise with virtual reality
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Universidad San Sebastián
Liver Transplant; Complications
Intraoperative "p50" Measurement in Liver Transplant Surgeries
The aim of this study is to compare the p50 value in routine blood gas measurements taken during liver transplant surgery follow-up with other follow-up parameters and clinical findings on the monitors, and to investigate whether…
- Trial name
- p50 (NCT06660095)
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Inonu University
Stroke, Stroke, Acute
Looking Glass: Bimanual Balanced Reaching With Visual Biofeedback
The goal of this research study is to increase understanding of error augmentation by applying it to visual feedback during motion tracking with a Leap Motion device - a recently developed optical hand tracking tool - and the…
- Conditions
- Stroke, Stroke, Acute, Healthy
- Trial name
- NCT03300141
- Testing
- Veridical Visual Feedback, Augmented Visual Feedback, Healthy Comparative Reaching Task
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Prehypertension
Pranayama and Jacobson's Progressive Muscle Relaxation Technique in Pre-hypertensive Patients
Objective of our study is to determine the comparative effects of Pranayama and Jacobson's Relaxation Technique on cardiovascular parameters, stress and quality of life in Pre-hypertensive patients.
- Trial name
- PRANvsJPMR (NCT06656130)
- Testing
- Pranayama, Jacobson's progressive muscle relaxation technique
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Bradyarrhythmias
Outcome of Patients Undergoing Leadless Pacemaker Implantaton
Observational study aimed to evaluate the rate and of complications related to lealdless pacemaker implantation.
- Trial name
- OPUPI (NCT06656468)
- Testing
- Pacemaker and defibrillator
- Where
- Italy
- Volunteers
- 900 people
- Sponsor
- Azienda Ospedaliera Cardinale G. Panico
Obesity
Development of Obesity and Bariatric Surgery
This study focus on the cause of obesity and impacts of bariatric surgery on it.
- Trial name
- NCT03296605
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Ventilation Therapy; Complications, Ventilator-Induced Lung Injury
Evaluation of Respiratory Mechanics in Supine and PARK-bench Positions (SPARK)
The primary objective of this prospective observational physiological study is to evaluate the variation in regional distribution of intrapulmonary volume in the dependent and non-dependent lung regions in patients undergoing…
- Trial name
- SPARK (NCT06448988)
- Testing
- Park Bench position
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Smoking, Adolescent Behavior
ADHAirE : a Randomized Controlled Trial to Improve the Implementation of Tobacco-free School Policies
The goal of this cluster randomized controlled trial is to learn if the set up of an advocacy coalition in secondary schools can improve the implementation of tobacco-free school policies (TFSP) to prevent adolescent smoking.
- Trial name
- NCT06655038
- Testing
- Advocacy coalition, Feedback
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Diabetes Mellitus, Diabetic Foot Disease
Diabetic Foot Education
To determine the effect of foot care training given according to Interpersonal Relationship Theory on foot care behaviour and diabetic foot self-efficacy.
- Trial name
- NCT06655116
- Testing
- Diabetic Foot Education
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- TC Erciyes University
Cardiovascular Disease With Mention of Arteriosclerosis, Elevated Cholesterol
Long-term Efficacy and Safety of OLE LIB003 in HoFH, HeFH, and High-risk CVD Patients Requiring Further LDL-C Reduction
The study is to assess the long-term safety, tolerability, and efficacy after 48 and 72 weeks with monthly (Q4W [<31 days]) dosing of subcutaneous (SC) LIB003 300 mg administered in patients with CVD or at high risk for CVD…
- Conditions
- Cardiovascular Disease With Mention of Arteriosclerosis, Elevated Cholesterol, Familial Hypercholesterolemia
- Trial name
- LIBerate-OLE (NCT04798430)
- Testing
- lerodalcibep
- Where
- 12 sites in United States, India and 4 more
- Volunteers
- 2,000 people
- Sponsor
- LIB Therapeutics LLC
Myocarditis
Cardiovascular Imaging in Pediatric Myocarditis
This study aims to utilize cardiac magnetic resonance (CMR) to assist in the clinical diagnosis, conduct consecutive assessments for myocardial tissue in pediatrics with myocarditis, and explore effective predictive factors for…
- Trial name
- NCT06652399
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- West China Second University Hospital
Mpox (Monkeypox)
Mpox Biology, Outcome, Transmission and Epidemiology
The MBOTE-Kamituga clinical and virological characterization protocol is a prospective observational cohort study with clinical and virological description of suspected mpox cases and longitudinal follow-up of confirmed mpox…
- Trial name
- NCT06652646
- Where
- Democratic Republic of the Congo
- Volunteers
- 1,000 people
- Sponsor
- Institute of Tropical Medicine, Belgium
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