Clinical trials: enrolling by invitation
Angiocardiography, Heart Failure
Identification and Functional Study of Novel Biomarkers for Cardiovascular Diseases
Cardiovascular diseases, mainly represented by ischemic heart disease and heart failure, are the number one killers of human health today.
- Conditions
- Angiocardiography, Heart Failure, Ischemic Heart Disease, Acute Myocardial Infarction (AMI)
- Trial name
- NCT06690684
- Testing
- Hematological indicators, Serological indicators in patients with myocardial infarction, Levels of biomarkers in blood of patients with acute myocardial infarction
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Ya-Wei Xu
Smoking Behavior, Special Needs Child
Evaluation of the Effects of Passive Smoking and Parental Stress on Challenging Behaviors in Mentally Retarded Children With Urine Cotinine Levels
This research was planned to determine the effect of environmental cigarette smoke exposure and parenting stress level on the severity of challenging behaviors in mentally disabled children
- Trial name
- smoking (NCT06691022)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Tokat Gaziosmanpasa University
Exercise Training, Genetic Polymorphism
Effects of Exercise Training and Genetic Factors in Hypertensive Patients with Obstructive Sleep Apnea Sleep
The objective is to investigate the effects of exercise training in hypertensive individuals with obstructive sleep apnea (OSA) in neurovascular control taking into account genetic factors.
- Trial name
- NCT06687863
- Testing
- Exercise training
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- University of Sao Paulo General Hospital
Cancer, Social Support (Formal and Informal)
Social Needs App for Oncology Patients Phase II
SNAP ON II is a two-arm, parallel-group, multi-center, randomized trial for patients diagnosed with cancer who are planning to undergo expected uncomplicated surgical intervention for their cancer.
- Conditions
- Cancer, Social Support (Formal and Informal), Mobile Application
- Trial name
- SNAP-On II (NCT06688513)
- Testing
- Carealth Phone App, Let's Talk: Sharing information about Family Cancer Risk
- Where
- 3 sites in United States
- Volunteers
- 722 people
- Sponsor
- JHSPH Center for Clinical Trials
Addiction, Opioid
Role of High Frequency RTMS in Management of Opioid Use Disorder
This study aims to evaluate the role of repetitive Transcranial Magnetic Stimulation (rTMS) applied to the left dorsolateral prefrontal cortex (DLPFC) in reducing pain, decreasing craving, alleviating withdrawal symptoms…
- Conditions
- Addiction, Opioid, RTMS
- Trial name
- NCT06689072
- Testing
- rTMS, Psychotherapy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Haemodialysis
The Effect of Education Based on Orem's Self-Care Deficit Theory and Tele-Monitoring on Rational Drug Use in Haemodialysis Patients
Patients with chronic kidney disease may show altered pharmacokinetic and pharmacodynamic response to many drugs compared to patients with normal renal function.
- Trial name
- Haemodialysis (NCT06689228)
- Testing
- Rational Drug Use Training
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Akdeniz University
Conjunctivitis, EBV Infection
Investigating Epstein-Barr Virus Associated Conjunctivitis
Conjunctivitis means inflammation of the conjunctiva, the thin transparent layer over the white of the eye and under the eyelids.
- Trial name
- EBV Conj (NCT06689397)
- Where
- United Kingdom
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Collagen Supplementation
Influence of Specific Collagen Peptides on Training-Induced Metabolic and Biomechanical Adaptations of Skeletal Muscle
This study investigates whether taking daily collagen peptides, combined with long-term endurance or concurrent training can enhance running economy through muscle and/or tendon adaptations.
- Trial name
- NCT06689761
- Testing
- ColCT, ColET, PlaCT
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Vienna
NSCLC
Perioperative Treatment Outcomes of Early NSCLC
This is an observational study evaluating the clinical characteristics, treatment patterns, and clinical outcomes of perioperative NSCLC patients receiving different treatment strategies.
- Trial name
- Peri-R (NCT06610240)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shanghai Chest Hospital
Gastrointestinal Diseases
Evaluation of Early Mobilization Protocol in Patients Undergoing Gastrointestinal Surgery
In this study, the investigators aimed to evaluate the early mobilization protocol created in accordance with the accelerated recovery guide after surgery in patients undergoing gastrointestinal surgery.
- Trial name
- NCT06679478
- Testing
- Enhanced Recovery After Surgery (ERAS) Early Mobilization Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Uludag University
Pancreatic Neoplasms
The Differences of Complications Between LPD(Laparoscopic Pancreaticoduodenectomy) and OPD(Open Pancreaticoduodenectomy)
Main objective: This project intends to design a simulated RCT project and clinically relevant RCT study to target, selecting the study titled "Short-Term outcomes Following Laparoscopic vs Open Pancreaticoduodenectomy in…
- Trial name
- TDCBLAP (NCT06685939)
- Testing
- LPD
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Zhijun Bao
Mild Cognitive Impairment
WAVE: AudioVisual Stimulation Enhances Cognitive, Mental and Physical Health in Elderly
The goal of this randomized controlled trial is to 1) carry out a screening of cognitive function, depressive symptoms, agility and functional balance and chronic inflammatory conditions in older adults; 2) analyze the influence…
- Trial name
- NCT06686563
- Testing
- Intervention Group: Gamma stimulation, Control Group: Theta stimulation
- Where
- Portugal
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Maria Paço
Gestational Diabetes, Hypertension in Pregnancy
Sleep Improvement Therapy Affects Pregnancy Outcomes in Chinese Singletons and Twins by Improving Sleep Quality
During pregnancy, the physical and psychological changes of pregnant women, hyperemesis gravidarum, uterine compression, frequent urination, hip or pelvic pain, back pain, leg cramps, gastroesophageal reflux, changes in mental…
- Conditions
- Gestational Diabetes, Hypertension in Pregnancy, Preterm Labor, NICU Infants
- Trial name
- NCT06687044
- Testing
- Sleep restriction, Stimulation control, Cognitive therapy
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Jun Wei
Age-Related Macular Degeneration
Deciphering AMD by Deep Phenotyping and Machine Learning- Prospective Study - SUMMIT (Part 2)
We will conduct a prospective, non-interventional roll-over extension of the PINNACLE study (Deciphering AMD by deep phenotyping and machine learning).
- Trial name
- NCT06682455
- Where
- 8 sites in Austria, United Kingdom
- Volunteers
- 300 people
- Sponsor
- University of Southampton
Mild Cognitive Impairment (MCI)
Comparison of Different Training Programs on Cognitive Function
The goal of the project is to identify the most effective exercise modalities in terms of neuroprotective effects and FP improvement.
- Trial name
- NCT06682741
- Testing
- Exercise
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
DIABETES Mellitus Type 2 Not Well Controlled
Effect of Flaxseed as a Treatment for Adults With Type 2 Diabetes Mellitus in Mexico
Type 2 Diabetes Mellitus represents one of the most important health emergencies of this century Although it is known that insulin resistance is reversible and that type 2 diabetes mellitus is controllable with a change towards a…
- Trial name
- NCT06683235
- Testing
- flaxseed
- Where
- Mexico
- Volunteers
- 160 people
- Sponsor
- Universidad Autónoma Benito Juárez de Oaxaca
Hypertrophic Cardiomyopathy (HCM)
Evaluation of Clinical Efficacy and Prognosis in Patients With Hypertrophic Obstructive Cardiomyopathy Through Hemodynamic Modeling Reconstructed by CT
Hypertrophic cardiomyopathy (HCM) is a common autosomal dominant inherited heart disease, with previous data suggesting a prevalence of approximately 1 in 500 in the population.
- Trial name
- NCT06683872
- Testing
- surgical myectomy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Zhejiang Provincial People's Hospital
Macular Hole, Macular Hole Surgery
Minimal Vitrectomy and ILM Flap with Sodium Hyaluronate Gel for MH
The purpose of this clinical trial is to compare the prognostic validity of two different surgical approaches: minimal posterior pole vitrectomy combined with a sodium hyaluronate gel-covered internal limiting membrane(ILM) flap…
- Conditions
- Macular Hole, Macular Hole Surgery, Idiopathic Macular Hole, Macular Hole of Left Eye (Disorder)
- Trial name
- ILM MH (NCT06685328)
- Testing
- minimal posterior pole vitrectomy combined with a sodium hyaluronate gel-covered internal limiting membrane(ILM) flap with balanced saline filling and postoperative supine position, Conventional vitrectomy combined with inner limiting membrane flap flip coverage with sterile air filling and postoperative prone position
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Jie Zhong
Parkinson's Disease (PD), Deep Brain Stimulation
The Relation Between the Prognosis of Subthalamic Nucleus Deep Brain Stimulation Surgery by Microlesion Effect and Electrode Position
BACKGROUND: Parkinson's disease (PD) is a common movement disorder whose main symptoms include resting tremor, rigidity and bradykinesia.
- Trial name
- Microlesion Ef (NCT06685510)
- Testing
- the score of UPDRS item
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Muscle Hypertrophy, Muscular Strength
The Effect of Peak Force At Long and Short Muscle Lengths and the Impact on Muscle Growth and Strength
The goal of this clinical trial is to learn the effect of applying peak force/resistance to skeletal muscles during resistance exercise training in young and healthy adults.
- Trial name
- SLML (NCT06666127)
- Testing
- LONG and SHORT Resistance Training, Maximal Isotonic Strength Testing (1RM), Isokinetic Strength Testing
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
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