Clinical trials: sponsored by Bristol-Myers Squibb
HIV Infections
A Comparative Phase I Clinical Study of HIVAC-1e and Smallpox (Vaccinia) Vaccines in Previously (Vaccinia) Vaccinated and Unvaccinated Volunteers
To determine the physiological and immunological responses in healthy HIV seronegative adult volunteers vaccinated with a) the HIVAC-1e (vaccinia-HIV) vaccine expressing the envelope glycoproteins of HIV and b) the Wyeth smallpox…
- Trial name
- NCT00002261
- Testing
- Smallpox Vaccine, HIVAC-1e, gp160 Vaccine (MicroGeneSys)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Schizophrenia, Schizoaffective Disorder
Abilify Therapy for Reducing Comorbid Substance Abuse
It is hypothesized that the use of aripiprazole (Abilify) in patients with alcohol and/or drug dependence with comorbid psychiatric conditions will lead to: Reduction in the amount of alcohol and/or drugs used as measured by the…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depressive Disorder
- Trial name
- NCT00208169
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Creighton University
HIV Infections
A Treatment IND (Investigational New Drug) Protocol for the Use of Videx (2',3'-Dideoxyinosine, ddI) in Patients With Acquired Immunodeficiency Syndrome (AIDS) or AIDS- Related Complex (ARC) Who Are Intolerant to Zidovudine (Retrovir)
The objective of this treatment IND protocol is to make didanosine (ddI) available to patients with HIV infection (suffering from AIDS related complex (ARC) or AIDS) who have developed documented intolerance to zidovudine (AZT)…
- Trial name
- NCT00002028
- Testing
- Didanosine
- Where
- United States
- Sponsor
- Bristol-Myers Squibb
Coronary Artery Disease, Ischemia
EArly Discharge After Transradial Stenting of CoronarY Arteries: The EASY Study
HYPOTHESES Discharge on the same day after uncomplicated trans-radial coronary artery stenting is safe and effective. Hospitalized patients can be safely returned to the referring center the same day following trans-radial…
- Trial name
- NCT00169819
- Testing
- Abciximab
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- Laval University
Schizophrenia, Schizoaffective Disorder
Aripiprazole for the Treatment of Schizophrenia With Co-Morbid Social Anxiety
This study will determine the efficacy of a medication switch to Aripiprazole for the treatment of schizophrenia or schizoaffective disorder in patients with moderate to high symptoms of social anxiety.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Social Anxiety Disorder
- Trial name
- NCT00177008
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Carcinoma, Non-Small-Cell Lung
Study for Patients With Non Small Cell Lung Cancer (NSCLC)
This is a randomized study to assess the efficacy and safety of chemotherapy with platin compared to chemotherapy without platin.
- Trial name
- NCT00168883
- Testing
- Carboplatin, Paclitaxel, Vinorelbine
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Charite University, Berlin, Germany
Chronic Kidney Disease
Anti-Oxidant Therapy In Chronic Renal Insufficiency (ATIC) Study
The ATIC study is a randomised, double- blind, placebo-controlled trial in which the effects of oxidative stress-lowering treatment on vascular function and structure are studied in patients with chronic non-diabetic renal…
- Trial name
- NCT00384618
- Testing
- pravastatin, vitamin E
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Amsterdam UMC, location VUmc
Puerperal Sepsis
Prophylactic Intrapartum Antibiotics and Immunological Markers for Postpartum Morbidity in HIV Positive Women
Postpartum infections are among the leading causes of maternal mortality world-wide, particularly in under-resourced countries. Available data suggests that HIV infected women are at greater risk of postpartum complications than…
- Trial name
- NCT00343317
- Where
- South Africa
- Volunteers
- 1,372 people, healthy volunteers welcome
- Sponsor
- University of KwaZulu
Burns
Fluid Shifts During Resuscitation: Impacts on Macrocirculation and Microcirculation
Fluid resuscitation in burn patients is associated with major macrocirculatory and microcirculatory disturbances that have been poorly described.
- Trial name
- NCT00326729
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Montreal Burn Centre
Type 2 Diabetes, Microalbuminuria
Irbesartan in Type 2 Diabetes
The aim of this multicenter, doubleblind, randomized study was to investigate the renoprotective effect of irbesartan treatment in patients with type 2 diabetes and microalbuminuria (a precursor of diabetic kidney disease).
- Conditions
- Type 2 Diabetes, Microalbuminuria, Hypertension
- Trial name
- NCT00317915
- Testing
- Irbesartan treatment
- Sponsor
- Steno Diabetes Center Copenhagen
Breast Cancer
Maintenance Chemotherapy in Metastatic Breast Cancer
This is a randomized, prospective and multicenter phase III study. Two-hundred-sixty-two (262) patients on each arm will be recruited in the study.
- Trial name
- NCT00289263
- Testing
- Paclitaxel
- Where
- 7 sites in Italy
- Volunteers
- 524 people
- Sponsor
- MANTA 1 Study Italian Collaborative Group
Breast Cancer
UFT/LV Maintenance Vs Observation in Metastatic Breast Cancer Responsive to Chemotherapy
To compare maintenance therapy to observation in metastatic breast cancer patients responding (or stabilized) after 1st-line chemotherapy. Main endpoint is disease-free survival.
- Trial name
- NCT00189631
- Testing
- UFT/LV, Observation
- Where
- France
- Sponsor
- Association Européenne de Recherche en Oncologie
Atrial Fibrillation, Hypertension
Irbesartan for the Prevention of Atrial Arrhythmias and Cardiac Electrical Remodeling in Patients With Hypertension and Permanent Pacemakers
The purpose of this study is to determine whether irbesartan will reduce the rate of recurrent atrial high rate episodes and the development of clinical sustained atrial fibrillation in patients with hypertension and permanent…
- Trial name
- NCT00225667
- Testing
- Irbesartan
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Connolly, Stuart, M.D.
HIV Infection, AIDS
Once Daily 3TC, Efavirenz and ddI for HIV Infection
Poor compliance is thought to be a major cause of treatment failure. The TEddI study is a randomised, multi-centre, open-label study in well-controlled treatment-experienced HIV-infected patients to assess compliance with a…
- Trial name
- NCT00214435
- Testing
- once daily minimum 3-drug regimen of anti-retroviral medications
- Where
- Australia
- Volunteers
- 120 people
- Sponsor
- 407 Doctors
HIV
Evaluation of Viral Efficacy and Safety of a Reduced Dose of Stavudine (d4T): THE PHOENIX STUDY
Lipodystrophie, peripheral neuropathy and mitochondrial toxicity has been associated to stavudine at standard doses The aim of this study is to evaluate the efficacy of reduced doses of stavudine (30 mg b.i.d.) in HIV patients…
- Trial name
- NCT00235222
- Testing
- stavudine
- Where
- France
- Volunteers
- 57 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Breast Cancer
6 FEC 100 Vs 4 FEC 100 Followed by 4 Taxol in N+ Breast Cancer
The main objective of this randomized trial is to compare 6 FEC100 to 4 FEC100 + 4 Taxol in patients with resected node positive breast cancer. Main endpoint is disease free survival.
- Trial name
- NCT00189644
- Testing
- 6 FEC 100, 4 FEC 100 followed by 4 Taxol
- Sponsor
- Association Européenne de Recherche en Oncologie
Peripheral Arterial Disease, Hypercholesterolemia
Multifactorial Intervention on Cardiovascular Risk Factors in Subjects With Peripheral Arterial Disease
The purpose of this study was to evaluate whether an intensified multifactorial intervention program about cardiovascular risk factors in subjects with peripheral arterial disease (with and without diabetes mellitus), can improve…
- Conditions
- Peripheral Arterial Disease, Hypercholesterolemia, Hypertension, Diabetes Mellitus
- Trial name
- NCT00144937
- Testing
- Stepwise therapy for dyslipidemia, hypertension and diabetes, Dietary recommendations, Increase in physical activity
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Hospital de Sabadell
Esophageal Cancer
Selective Dose Escalation for Esophageal Cancer
This prospective study was designed to assess the outcomes (survival and failure patterns) of therapy for localized esophageal cancer with conventional dose radiation (RT; 50.4 Gy) with concurrent continuous infusion…
- Trial name
- NCT00139633
- Testing
- carboplatin, 5FU, Taxol and radiation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The Oregon Clinic
HIV Infections
Efficacy and Safety of Tenofovir DF/Atazanavir Enhanced With Low Dose of Ritonavir in HIV-Infected Patients
This trial is aimed at studying the antiviral activity, toxicity and pharmacokinetic (PK) interactions of tenofovir DF and atazanavir enhanced with low dose of ritonavir given alone and then concomitantly as part of a salvage…
- Trial name
- NCT00122577
- Testing
- Tenofovir, Atazanavir, Ritonavir
- Where
- France
- Volunteers
- 50 people
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
HIV Infections
Safety and Effectiveness of Giving an Anti-HIV Drug Combination of Adefovir Dipivoxil Plus Didanosine Plus Efavirenz Plus Lamivudine Once Daily to HIV-Infected Patients
The purpose of this study is to see if it is safe and effective to give HIV-infected patients a new combination of anti-HIV drugs taken once daily.
- Trial name
- NCT00002234
- Testing
- Efavirenz, Adefovir dipivoxil, Lamivudine
- Where
- 5 sites in United States
- Volunteers
- 25 people
- Sponsor
- Gilead Sciences