Clinical trials: completed, sponsored by University of Florida
Intraocular Pressure, Oncology
Effect of Position and Anesthetic Choice in Intraocular Pressure in Robotic GYN (Gynecologic) Oncology Patients
Steep Trendelenburg positioning and insufflation of the abdominal cavity have shown to increase intra ocular pressure. Different anesthetic techniques can alter intra ocular pressure and a small pilot study showed decrease in…
- Trial name
- NCT04281017
- Testing
- TIVA, Balanced anesthesia
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Florida
Chronic Kidney Disease 5D
High-protein Oral Supplement With Liposomal Curcumin in Adults Undergoing Hemodialysis.
A 12-week double-blind randomized control trial will be conducted among adults on hemodialysis (n=15) to determine the impact of liposomal curcumin in a high-protein product on inflammation markers and oxidative stress.
- Trial name
- NCT06381076
- Testing
- Liposomal curcumin, Food colorant
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Florida
Healthy
Fermented Papaya and Driving Simulator Older Adult Study
Yes, this additional detail will refine the original template content to emphasize the study's specific aims and hypotheses. Here's an updated version: The goal of this clinical trial is to assess if Fermented Papaya Preparation…
- Trial name
- FPP (NCT06672874)
- Testing
- Fermented Papaya Preparation (FPP)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Musculoskeletal Pain
Mechanisms and Modulation of Pain Modulatory Capacity
This project proposes to understand the sources of pain variability, and demonstrate that pain variability represents fluctuation in natural pain management.
- Trial name
- NCT04441619
- Testing
- Delayed onset muscle soreness.
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Florida
Overweight and Obesity, Time Restricted Feeding
Fasting ENHANCE Pilot Study
Grounded in the principles of geroscience, the proposed Fasting ENHANCE study will test whether a time restricted eating (TRE) regimen can improve cognitive function and other aspects of successful aging in a safe and sustainable…
- Conditions
- Overweight and Obesity, Time Restricted Feeding, Alzheimer Disease
- Trial name
- NCT05732935
- Testing
- Time Restricted Eating intervention, Successful Aging Comparison Group (LEARN)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Florida
Weight Gain Prevention, Physical Inactivity
Family Fit Iterative App Development
The overall aim of this study is to test the acceptability and usability of a mobile application (app) for family-based physical activity and weight gain prevention among parent/guardian and child (ages 9-12 years) dyads.
- Trial name
- NCT06148246
- Testing
- Family Fit Condition
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida
Chronic Musculoskeletal Pain
Krill Oil for Pain in Elders
Chronic musculoskeletal pain contributes to mobility disability among older adults. Nutritional interventions, like omega-3 fatty acids, may help manage pain and improve physical function.
- Trial name
- KOPE (NCT06580912)
- Testing
- Krill oil, Mixed vegetable oil
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Florida
Obesity, Uric Acid Stones
Phentermine/Topiramate for Uric Acid Stones
The investigator proposes an 18 month, feasibility pilot study, randomizing obese and diabetic individuals with pure uric acid nephrolithiasis (UAN) or mixed calcium oxalate (CO) UAN to either phentermine/topiramate or a…
- Conditions
- Obesity, Uric Acid Stones, Type 2 Diabetes Mellitus in Obese, Pre-Diabetes
- Trial name
- NCT04621929
- Testing
- Phentermine / Topiramate Oral Product, Citrate Salts, Allopurinol, Diet
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Florida
Hypertension
Improving Blood Pressure Control Among Food Insecure Hypertensive Adults
The overall objective of this project is to assess the feasibility, acceptability, and appropriateness of adapted community health worker (CHW)-led implementation strategies designed to improve intake of fruits and vegetables and…
- Trial name
- NCT05877898
- Testing
- CHW Education, CHW Education and Navigation
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Florida
Chronic Low Back Pain (CLBP)
A Mediation Analysis Investigating Dry Needling Treatment Mechanisms in a Chronic Low Back Pain Population
Low back pain is a common problem that many adults experience at some point in their lives. One treatment being studied is dry needling, a technique where a small needle is inserted into a specific area of muscle to help relieve…
- Trial name
- NCT06940492
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Florida
Type 1 Diabetes (T1D)
Lactobacillus Johnsonii Supplementation in Adults With T1D
While genetics demonstrated a major risk factor for the development of type 1 diabetes (T1D), microbiota dysbiosis has been suggested as an elicitor in immunological tolerance and of beta cell autoimmunity.
- Trial name
- NCT03961347
- Testing
- L. johnsonii Probiotic
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Florida
Musculoskeletal Injury
Fluoxetine Mitigation Mental Health Study for Patients With Musculoskeletal Trauma
Musculoskeletal trauma is one of the leading causes of disability in the United States and its negative quality of life impact extends beyond that of physical recovery.
- Trial name
- NCT04850222
- Testing
- Fluoxetine, Calcium
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Florida
Coronary Artery Disease
Effect of Beet Juice Supplementation on Vascular and Inspiratory Muscle Function
Older adults with coronary artery disease (CAD) have impaired vascular and inspiratory muscle function. The overarching goal of this double-blind, randomized, crossover, placebo-controlled pilot trial was to inform the…
- Trial name
- NCT04920799
- Testing
- Nitrate rich beetroot juice, Nitrate depleted beetroot juice
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Florida
Educational Problems
The Efficacy of Biplane Versus Single Plane Ultrasound in Facilitating Caudal Epidural Anesthesia in Pediatric Patients.
Ultrasound guidance plays a pivotal role in caudal epidural block in pediatric patients. In comparison to conventional single-plane ultrasound, biplane ultrasound offers the advantage of providing simultaneous transverse and…
- Trial name
- NCT06319989
- Testing
- Biplane Ultrasound, Single plane ultrasound
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Florida
Orthodontic Tooth Movement
Clinical Trial to Assess the Efficacy of Reducing the Aligners' Wear Protocol
The hypothesis of this project is that replacing the current 7-day wear protocol with a 3-day wear protocol, while integrating less tooth movement per aligner (reduce the amount of activation per aligner) may produce more…
- Trial name
- NCT05905224
- Testing
- Invisalign 7-day wear protocol, Invisalign 3-day wear protocol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Florida
Type 1 Diabetes (T1D)
Lactobacillus Johnsonii in Children and Adolescents With T1D
While genetics demonstrated a major risk factor for the development of type 1 diabetes (T1D), microbiota dysbiosis has been suggested as an elicitor in immunological tolerance and of beta cell autoimmunity.
- Trial name
- NCT03961854
- Testing
- L. johnsonii Probiotic
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Deviated Nasal Septum
Septorhinoplasty Post-operative Pain Control With SPG Nerve Block
Maxillary nerve blocks have been shown to significantly reduce post-operative pain and analgesic intake during the 24-hour period following sinus surgery.
- Trial name
- NCT05667324
- Testing
- Ropivacaine, Dexamethasone
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Florida
Sepsis
Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and Induced Frailty
The purpose of this study is to define the natural history and causes of chronic critical illness (CCI) in surgical intensive care patients who have had sepsis.
- Trial name
- NCT02711709
- Testing
- Frailty Measurements, Modified Minnesota Leisure Time Activities, Computed tomography morphometrics
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Florida
Chronic Low-back Pain
Integrative Breathwork Intervention for Chronic Pain
The proposed research is to develop and refine a multicomponent breathwork intervention, Guided Respiration Mindfulness Therapy, and to iteratively evaluate its feasibility, acceptability, and plausibility for clinically…
- Trial name
- NCT06546956
- Testing
- Integrative Breathwork Intervention
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Florida
Diarrhea, Cholera
Next Generation ORS: Comparing ORS With Calcium vs Standard ORS in Reducing Severity of Acute Watery Diarrhea
Diarrhea remains a leading killer of children in need of better treatments.
- Trial name
- ORS (NCT05814042)
- Testing
- Current standard control ORS (oral rehydration solution)
- Where
- Bangladesh
- Volunteers
- 396 people
- Sponsor
- University of Florida