Clinical trials: completed, sponsored by University of California, San Francisco
Autism Spectrum Disorder
Building Resilience and Appropriate Independence in Young Adults With Autism
This study evaluates the effects of a 12-week life-skills resilience curriculum for young adults with autism. The project utilizes a cohort single arm design.
- Trial name
- NCT03842332
- Testing
- Life Skills and Resilience Program
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Post Traumatic Stress Disorder
Remotely Resolving Psychological Stress (Remote RePS)
The investigators have developed a mobile app called Resolving Psychological Stress (REPS) for people with posttraumatic stress disorder (PTSD).
- Trial name
- NCT03196999
- Testing
- Personalized Attention Bias Training, Neutral Attention Training Condition, Non-Personalized Attention Bias Training
- Where
- United States
- Volunteers
- 689 people
- Sponsor
- University of California, San Francisco
Dementia, Alzheimer Disease
The Brain Health Study: A Pragmatic, Patient-Centered Trial
The eRADAR Brain Health Study is an embedded, pragmatic clinical trial to determine whether targeted screening for dementia using the eRADAR algorithm increases dementia detection within primary care compared to usual care.
- Trial name
- eRADAR (NCT05905796)
- Testing
- Brain Health Assessment
- Where
- 3 sites in United States
- Volunteers
- 1,261 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Type 2 Diabetes, Food Insecurity
Changing Health Through Food Support for Diabetes
This is a pragmatic randomized controlled trial (RCT) of Changing Health through Food Support for Diabetes (CHEFS-DM). This pragmatic RCT will leverage Project Open Hand's (POH) real-world programs to test the impact of a six…
- Trial name
- CHEFS-DM (NCT04959487)
- Testing
- Food support, Nutritional Counseling and education
- Where
- United States
- Volunteers
- 281 people
- Sponsor
- University of California, San Francisco
Atypical Anorexia Nervosa
Individualized Study of Refeeding to Optimize iNpatient Gains
The primary purpose of the trial is to compare the efficacy and safety of Individualized Caloric Refeeding (ICR) to the new standard of care, Higher Calorie Refeeding (HCR), in hospitalized patients with atypical anorexia nervosa…
- Trial name
- i-STRONG (NCT04966858)
- Testing
- Individualized Caloric Refeeding (ICR), Higher Calorie Refeeding (HCR)
- Where
- 2 sites in United States
- Volunteers
- 77 people
- Sponsor
- University of California, San Francisco
Drug Use
Using Technology to Reduce Youth Substance Use
The research project will focus on conducting a trial of whether a tailored SMS text-messaging intervention is efficacious in improving justice-involved youths' substance use or dual diagnosis treatment attendance and engagement.
- Trial name
- TEXT2 (NCT04446910)
- Testing
- SMS Text Messaging Plus, SMS Text Messaging
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
HIV
SEARCH CAB LA Dynamic Choice HIV Prevention Study Extension
The overall purpose of this SEARCH CAB-LA (Cabotegravir Injectable Suspension) randomized extension study is to determine if adding the option of CAB-LA as a prevention choice using a person-centered dynamic choice HIV (human…
- Trial name
- NCT05549726
- Testing
- Cabotegravir Injectable Suspension, Dynamic Choice Delivery Model, Standard of Care
- Where
- 2 sites in Kenya, Uganda
- Volunteers
- 984 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dilation, Pupil Reaction Absent
Efficacy of the MydCombi on Pupillary Dilation in Pediatric and Adult Patients
To raise the standard of care, improve the overall patient experience and streamline practice flow, Eyenovia has developed an innovative mydriatic to be delivered as a microdose by a specialized dispenser.
- Trial name
- NCT06366217
- Testing
- MydCombi Device, MydCombi Drug
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Francisco
Premature Birth, Pregnancy Preterm
Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) Study
This is a randomized comparative effectiveness study of two forms of enhanced prenatal care among 674 Medi-Cal eligible pregnant individuals in Fresno, California.
- Conditions
- Premature Birth, Pregnancy Preterm, Prenatal Stress, Depression, Anxiety
- Trial name
- EMBRACE (NCT04154423)
- Testing
- Glow! Group Prenatal Care, Individual Prenatal Care with CPSP
- Where
- 2 sites in United States
- Volunteers
- 678 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Acanthamoeba Keratitis, Fungal Keratitis
Rose Bengal Electromagnetic Activation With Green Light for Infection Reduction
Rose Bengal Electromagnetic Activation with Green light for Infection Reduction (REAGIR ) is an international, randomized, doubled masked, clinical trial.
- Trial name
- REAGIR (NCT05110001)
- Testing
- Moxifloxacin Ophthalmic, Chlorhexidine Gluconate, Natamycin
- Where
- 2 sites in Brazil, India
- Volunteers
- 330 people
- Sponsor
- University of California, San Francisco
Anesthesia, Surgery
Norepinephrine vs Phenylephrine During General Anesthesia
50 million patients undergo surgery each year in the United States. Postoperative mortality is considered the third leading cause of death worldwide.
- Conditions
- Anesthesia, Surgery, Hypotension
- Trial name
- VEGA-1 (NCT04789330)
- Testing
- Norepinephrine, Phenylephrine
- Where
- 5 sites in United States
- Volunteers
- 3,626 people
- Sponsor
- University of California, San Francisco
HIV/AIDS
Combinatorial Therapy to Induce an HIV Remission
Combination approaches will almost certainly be required to generate durable control of HIV in the absence of antiretroviral therapy (a "remission").
- Trial name
- NCT04357821
- Testing
- Combination Intervention
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, San Francisco
Motility Function
Esophageal Manometry During Recovery From Anesthesia: Pilot Study
1. An intact pharyngoesophageal reflex is essential to protect the upper airway from aspiration of either mouth contents or regurgitated gastric refluxate. This reflex is essential at protecting the airway in all patients. 2.
- Trial name
- EMAP (NCT02661386)
- Testing
- Motility Procedure
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Mortality, Resistance Bacterial
Azithromycin for Child Survival in Niger: Mortality and Resistance Trial
The MORDOR trial found that biannual distribution of azithromycin to children 1-59 months old reduced child mortality. The World Health Organization (WHO) released conditional guidelines for this intervention, which include…
- Conditions
- Mortality, Resistance Bacterial, Child, Only
- Trial name
- AVENIR (NCT04224987)
- Testing
- Azithromycin
- Where
- Niger
- Volunteers
- 864,493 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
HIV Infections, Stigma, Social
HIV Prevention Peer Navigation for Justice Involved Women
Women involved in the criminal justice system have complex and highly stigmatized sexual and substance use risk profiles and are particularly vulnerable to, and experience, high rates of HIV.
- Trial name
- kINSHIP (NCT04680390)
- Testing
- Standard of care engagement practices, Peer Navigators Addressing INtersectional Stigma to Improve HIV Prevention Among Criminal-Justice Involved Women
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Human Immunodeficiency Virus Transmission, Sexually Transmitted Diseases
The OPENS Trial: Offering Women PrEP (Aim 1)
To address the significant barriers to PrEP implementation for those who were assigned female at birth and self-identify as a woman and address racial inequities in HIV prevention in the United States (US), a novel approach that…
- Trial name
- NCT04621760
- Testing
- HIV Prevention Decision Support Tool (DST), Standard Counseling
- Where
- United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Progressive Multiple Sclerosis, Fatigue
A Study of Oxidative Pathways in MS Fatigue
This is a 4-week randomized, placebo-controlled, parallel group, double-blind, single center trial on effect of N-acetyl cysteine versus placebo on fatigue in patients with progressive MS defined by McDonald criteria.
- Trial name
- NCT02804594
- Testing
- N-acetyl cysteine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Smoking Cessation, Smoking, Tobacco
PARQuit Smoking Cessation Intervention for Adults With Serious Mental Illness
This is a research study investigating a smoking cessation program tailored for adults with serious mental illness (SMI). The program uses a Videogame-based Physical (VIP) activity, smoking cessation counseling, and medication…
- Conditions
- Smoking Cessation, Smoking, Tobacco, Mental Illness, Tobacco Use Disorder
- Trial name
- PARQuit (NCT03950427)
- Testing
- Videogame-based physical activity, Sedentary videogame, Bupropion
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of California, San Francisco
Severe Acute Malnutrition
Mother Screening for Relapse Using Mid-upper Arm Circumference Among Children Recovered From Severe Acute Malnutrition
The investigators propose a pilot randomized controlled trial to train mothers to screen their children post-discharge for relapse based on MUAC criteria to facilitate timely identification and referral to care for children who…
- Trial name
- NCT05932992
- Testing
- Mother education on how to perform MUAC assessment
- Where
- Burkina Faso
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Chronic Low-back Pain
Development and Feasibility of Mindfulness Based Pain Reduction
This is a development study with clinical outcomes. The investigators aim to develop and test an 8-week MBPR (Mindfulness-Based Pain Reduction) program, which draws on intervention work and clinical experience in the…
- Trial name
- MBPR (NCT04980612)
- Testing
- Mindfulness Based Pain Reduction, Mindfulness Based Stress Reduction
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of California, San Francisco