Clinical trials: completed, sponsored by University of British Columbia
Hip Osteoarthritis
Feasibility of the Hip Instructional Prehabilitation Program for Enhanced Recovery (HIPPER)
Osteoarthritis (OA), leading to hip replacement, is a leading contributor to global mobility impairment. Given the boom in the older demographic it is not surprising that there is an 11% increased demand for replacement every 5…
- Trial name
- HIPPER (NCT02969512)
- Testing
- HIPPER, OASIS Online Educational Webinars
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- University of British Columbia
Joint Disease, Rheumatoid Arthritis
an On-demand Program to EmpoweR Active Self-management (OPERAS)
Self-management is a key component of successful chronic disease management and patients can benefit from learning about how daily activities and treatments relate to their symptoms and health status on an ongoing basis.
- Trial name
- OPERAS (NCT03404245)
- Testing
- Education, Fitbit/self-management app, physiotherapist counselling., Same intervention with a 6 month delay
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- University of British Columbia
Joint Diseases, Knee Osteoarthritis
SuPRA: Using Wearable Activity Trackers With a New Application to Improve Physical Activity in Knee Osteoarthritis
Physical activity is an essential first-line treatment for patients with knee osteoarthritis (OA). However, only 13% of patients meet the activity recommendation of 150 minutes or more per week.
- Trial name
- NCT02585323
- Testing
- Education session, Fitbit/FitViz, PT counselling, Same intervention with a 3 month delay
- Where
- 2 sites in Canada
- Volunteers
- 51 people
- Sponsor
- University of British Columbia
Ketosis, Type 2 Diabetes
Exogenous Ketones in Type 2 Diabetes
Exogenous ketone supplements are proposed to have glucose-lowering potential, provide an alternative fuel for the brain and to enhance cognitive function.
- Trial name
- NCT04194450
- Testing
- Ketone monoester
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- University of British Columbia
Sepsis, Infection
Paediatric Rapid Sepsis Trigger (PRST) Tool
Sepsis is the leading cause of death and disability in children, every hour of delay in treatment is associated with greater organ damage and ultimately death.
- Trial name
- PRST (NCT04304235)
- Testing
- Pediatric Rapid Sepsis Trigger (PRST) tool, Emergency Triage and Treatment (ETAT) guidelines
- Where
- 3 sites in Kenya, Uganda
- Volunteers
- 18,693 people
- Sponsor
- University of British Columbia
Elevated Blood Sugar
Power of Choice on Autonomy, Motivation, Exercise Adherence, and Cardiorespiratory Fitness
People with elevated blood sugar levels are at increased risk of developing chronic medical conditions such as obesity, type 2 diabetes, and cardiovascular disease.
- Trial name
- NCT03576924
- Testing
- MICT, HIIT, CHOICE
- Where
- Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Ozone Exposure During Rest and Exercise
Susceptibility of Cardiorespiratory Responses to Ozone During Cycling Exercise
Ground level ozone (O3) is a common airborne pollutant that is well recognized to cause negative respiratory symptoms and impair pulmonary function.
- Trial name
- NCT05473000
- Testing
- Exercise, Ozone, Room air
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Maternal Sepsis, Neonatal Sepsis
Smart Discharges for Mom & Baby
This study aims to build a predictive algorithm that identifies mother-newborn dyads most at risk of death or complications in the 6 weeks after birth.
- Trial name
- NCT05730387
- Testing
- Observational only
- Where
- Canada
- Volunteers
- 7,182 people
- Sponsor
- University of British Columbia
Sacroiliac Strain, Low Back Pain
Correction of Low Back Pain From Sacroiliac Malrotation With a Simple in Home Exercise
60 participants with low back pain will be examined to determine the direction and extent of sacroiliac malrotation. If malrotation exists, they will be randomized to 3 treatment groups: 1 will be taught how to use their thigh to…
- Trial name
- SIbackpain (NCT03888235)
- Testing
- Immediate corrective exercises, Immediate use of pelvic support belt, Delayed treatment
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy
Efficacy of Movement Breaks in Real-World Settings
The purpose of this study is to determine the efficacy of performing "exercise snacks" (short movement breaks throughout the day) on various measures of cardiometabolic health.
- Trial name
- NCT05574426
- Testing
- Movement Breaks
- Where
- 2 sites in Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Asthma and/or Exercise Induced Bronchoconstriction, Ozone Air Pollution
Salbutamol Use in Ozone Air Pollution by People With Asthma and/or Exercise Induced Bronchoconstriction (EIB)
Salbutamol use is increased in areas with high levels of ozone pollution and the potential consequences of this are not well known.
- Trial name
- NCT05087693
- Testing
- Salbutamol, Ozone, Filtered Air
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University of British Columbia
Chronic Pain, Cancer
Immersive Multimedia as an Adjunctive Measure for Pain Control in Cancer Patients
This study seeks to explore the efficacy of immersive multimedia experiences as a practical adjunctive therapeutic intervention in the self-management of the chronic pain associated with cancer patients.
- Trial name
- NCT02995434
- Testing
- Virtual Reality Headset, 2D PC
- Where
- 3 sites in Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Type 2 Diabetes, Type 1 Diabetes
Dark Chocolate and Glucose Levels in Diabetes
Diabetes is a growing concern in the world with an estimated 9.3% of adults, ages 20-79, with it in 2019, type 2 diabetes accounting for 90% of this total.
- Trial name
- NCT04847999
- Testing
- Dark chocolate
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of British Columbia
Dietary Habits
Low-carbohydrate Versus Low-fat Breakfast in Type 2 Diabetes
The prevalence of type 2 diabetes (T2D) is increasing worldwide, with ~380 M currently suffering from this chronic, debilitating disease. T2D is characterized by high blood glucose levels in the mornings and after meals.
- Trial name
- NCT04550468
- Testing
- Low-Carb High-Fat breakfast, Low fat "standard care" control breakfast
- Where
- Canada
- Volunteers
- 127 people
- Sponsor
- University of British Columbia
Acute Graft Rejection, Diabetes
A Pilot Study Comparing the Use of Low-target Versus Conventional Target Advagraf
While the incidence of acute rejection and early graft loss have improved dramatically with the advent of newer immunosuppressant medications, improvements in long-term patient and allograft survival after kidney transplantation…
- Trial name
- Astellas (NCT01265537)
- Testing
- Tacrolimus
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Low Female Sexual Desire
Randomized Comparison of Mindfulness Versus Group Support for Treatment of Low Sexual Desire in Women
The purpose of this study is to determine whether an 8-session mindfulness-based intervention (MBCT group) is effective for women with low sexual interest/desire in reducing sexual distress, improving their sexual response, and…
- Trial name
- DESIRE (NCT01690897)
- Testing
- Mindfulness-based treatment, Sex therapy, education, and support treatment
- Where
- Canada
- Volunteers
- 149 people
- Sponsor
- University of British Columbia
Spinal Cord Injuries
ProACTIVE SCI Physical Activity Intervention
This study will employ a randomized, wait-list controlled trial. A total of 30 participants (15 experimental, 15 wait-list control) between 18-65 years of age who have chronic SCI ≥ 1 year prior will be recruited.
- Trial name
- NCT03111030
- Testing
- ProacTive SCI
- Where
- 2 sites in Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Osteoarthritis, Knee
Telerehabilitation Gait Modification
Excessive knee joint loads during walking can contribute to knee osteoarthritis progression. Changing the rotation of the foot (in-toeing or out-toeing) while walking can lower knee joint loads and improve pain and function.
- Trial name
- TELEMOD (NCT04683913)
- Testing
- Foot rotation modification, Waiting Period - Delayed Group
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Ketosis, Blood Glucose
The Effect of Different Ketone Supplements on β-OHB and Blood Glucose in Healthy Individuals
Ketone bodies are a fuel source and signaling molecule that are produced by your body during prolonged fasting or if you consistently eat at low-carbohydrate diet.
- Trial name
- NCT05273411
- Testing
- (R)-3-hydroxybutyl (R)-3-hydroxybutyrate ketone monoester, Beta-hydroxybutyric acid, 1,3-Butanediol
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Sickle Cell Disease, Sickle Cell Trait
Evaluation of Low-cost Techniques for Detecting Sickle Cell Disease and β-thalassemia in Nepal and Canada
Sickle cell disease (SCD) is an inherited blood disorder associated with acute illness and organ damage. In high resource settings, early screening and treatment greatly improve quality of life.
- Conditions
- Sickle Cell Disease, Sickle Cell Trait, Beta-Thalassemia, Sickle Cell-Beta Thalassemia
- Trial name
- NCT05506358
- Testing
- High performance liquid chromatography, Automated sickling test, HbS solubility test
- Where
- 3 sites in Canada, Nepal
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of British Columbia