Clinical trials: open to volunteers, sponsored by Stanford University
Schizophrenia Disorder, Schizoaffective Disorder
Incentives and Long-Acting Injectable Adherence After Involuntary Hospitalization
This study is a randomized controlled trial evaluating the impact of financial incentives on medication adherence among individuals with schizophrenia, schizoaffective disorder, or bipolar disorder and/or co-occurring substance…
- Conditions
- Schizophrenia Disorder, Schizoaffective Disorder, Bipolar Disorder (BD), Substance Use Disorder (SUD)
- Trial name
- NCT07130500
- Testing
- Financial incentives for adherence to long-acting injectable medication, Standard of care with monthly surveys
- Where
- 6 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Stanford University
Glaucoma
Topical Insulin for Glaucoma
The purpose of this Phase 1 trial is to determine the safety over 1-2 months of topic sterile human recombinant insulin on subjects with optic neuropathies (glaucoma, ischecmic optic neuropathy, and optic disc drusen).
- Trial name
- TING1 (NCT05206877)
- Testing
- Insulin, 4 units, Insulin, 20 units, insulin, 4 units twice daily
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Stanford University
Alcohol Abuse, Alcohol Use Disorder
A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners
The purpose of this study is to evaluate the efficacy of an adaptive web intervention (Partners Connect) on military spouse drinking behaviors (CPs) and service member help-seeking (SMs).
- Conditions
- Alcohol Abuse, Alcohol Use Disorder, Alcohol Drinking, Relations, Interpersonal
- Trial name
- NCT05619185
- Testing
- CRAFT Web-Based Intervention, Phone-Based CRAFT, CRAFT Workbook
- Where
- United States
- Volunteers
- 744 people, healthy volunteers welcome
- Sponsor
- Stanford University
Chronic Pain, Cesarean Section Complications
Reducing Chronic Pain Following Cesarean Delivery
This pilot study will evaluate the feasibility and acceptability of delivering Empowered Relief (ER), a single-session pain relief skills class, to postpartum women with ongoing pain and/or pain interference following cesarean…
- Conditions
- Chronic Pain, Cesarean Section Complications, Postpartum
- Trial name
- NCT07799883
- Testing
- Empowered Relief
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Major Depressive Disorder (MDD)
Sedation and Guided Education for Depression Study
The goal of this clinical trial is to understand how patient education surrounding a one-time, consciousness-altering medical intervention impacts the antidepressant response to the intervention in adults with major depressive…
- Trial name
- SAGE (NCT06705270)
- Testing
- Response-focused education, Diagnosis-focused education, IV naloxone
- Volunteers
- 40 people
- Sponsor
- Stanford University
Post-Bariatric Hypoglycemia
Dietary, Medication, and Endoscopic Interventions for Post-Bariatric Hypoglycemia
Post-bariatric hypoglycemia (PBH) is a complication of upper gastrointestinal surgery that causes recurrent episodes of low blood sugar after eating and can substantially impair quality of life.
- Trial name
- NCT07878494
- Testing
- Dietary Intervention, GLP-1 receptor agonist or Dual GIP/GLP-1 receptor agonist, Transoral Outlet Reduction (TORe)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
ACL Tear
Quadriceps Strengthening ACL Reconstruction
The purpose of this study is to characterize quadriceps function and squat biomechanics during the early strengthening phase in adolescent patients undergoing a standardized combined neuromuscular electrical stimulation (NMES)…
- Trial name
- ACL (NCT07015541)
- Testing
- NMES and BFR, Standard physical therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stanford University
Stroke Recurrence, Myocardial Infarction
Cilostazol for Prevention of Recurrent Stroke Trial
The goal of this clinical study is to learn if adding a medicine called cilostazol to usual treatment can help prevent another stroke, a heart attack, or death in patients who had a stroke caused by a blocked blood vessel, or a…
- Conditions
- Stroke Recurrence, Myocardial Infarction, Vascular Death, Ischemic Stroke
- Trial name
- Clarity (NCT07174414)
- Testing
- Cilostazol 100 mg Tablets
- Where
- 46 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- Stanford University
Alcohol Misuse
Advancing Scalable Alcohol Brief Interventions in the ED: A Trial of Conversational AI With Digital Reinforcements
The goal of this clinical trial is to learn if a novel digital strategy combining a generative AI counseling agent (MICA) and weekly SMS boosters works to reduce risky drinking among Emergency Department patients.
- Trial name
- MICA-ED (NCT07661563)
- Testing
- MICA, TRAC
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- Stanford University
Acute Myeloid Leukemia (AML)
Niclosamide in Pediatric Patients With Relapsed and Refractory AML
Protocol is designed to evaluate a niclosamide dose escalation scale in combination with cytarabine as a therapeutic modality for pediatric subjects with relapsed/refractory acute myeloid leukemia.
- Trial name
- NCT05188170
- Testing
- Niclosamide
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Stanford University
Open Angle Glaucoma, Primary Open Angle Glaucoma
Topical Insulin for Glaucoma (TING2)
This study evaluates the safety and preliminary efficacy of topical sterile human insulin eye drops (EYED-002) in patients with open-angle glaucoma.
- Conditions
- Open Angle Glaucoma, Primary Open Angle Glaucoma, Low Tension Glaucoma, Pigmentary Glaucoma
- Trial name
- NCT07619482
- Testing
- EYED-002 Low Dose (721 U/mL topical insulin), EYED-002 High Dose (1442 U/mL topical insulin), EYED-002 (highest tolerated dose, 12-month)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Stanford University
Pregnancy - Labor Monitoring, Labor and Childbirth
Wearable Ultrasound Patch in Parturients
This study will assess an investigational ultrasound patch placed on the maternal abdomen to noninvasively monitor uterine activity, obtain fetal images and physiologic measurements in labor.
- Conditions
- Pregnancy - Labor Monitoring, Labor and Childbirth, Fetal Heart Rate Tracing
- Trial name
- NCT07871903
- Testing
- wearable ultrasound patch
- Volunteers
- 40 people
- Sponsor
- Stanford University
Optic Neuropathy, Glaucoma
Hyperbaric Oxygen Therapy for Optic Neuropathies
The purpose of the study is to evaluate the neuroprotective efficacy of hyperbaric oxygen for the treatment in patients with optic neuropathy.
- Trial name
- HBOT (NCT06128720)
- Testing
- Hyperbaric Oxygen
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Glaucoma, Glaucoma Open-Angle
Electrical Stimulation for Vision Neuroenhancement in Glaucoma
The purpose of the study is to evaluate the efficacy, transorbital alternating current stimulation (rtACS) using the EYETRONIC for the treatment in patients with glaucoma.
- Trial name
- NCT06685211
- Testing
- Eyetronic rtACS
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Medulloblastoma, Central Nervous System Embryonal Tumor
GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults
This is a single-site, open-label Phase I treatment study evaluating the manufacturing feasibility and safety of chimeric antigen receptor (CAR) T cells targeting the oncofetal protein Glypican-2 (GPC2) in pediatric and young…
- Conditions
- Medulloblastoma, Central Nervous System Embryonal Tumor, Refractory Medulloblastoma, Recurrent Medulloblastoma
- Trial name
- NCT07087002
- Testing
- GPC2-CAR T cells, Fludarabine, Cyclophosphamide
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Stanford University
Air Pollution Exposure
Voices Illuminating Solutions for Outdoor Workers' Needs and Safety
The goal for this multidisciplinary randomized controlled trial (RCT) is to actively and meaningfully engage outdoor workers (can include agricultural workers, construction workers, landscaping, wildland firefighters, fire…
- Trial name
- VISIONS (NCT07713264)
- Testing
- Receive education on heat and air quality health risks, Participate in Photovoice and climate health risk education
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stanford University
Ductal Breast Carcinoma in Situ
Surgical Excision vs Neoadjuvant Radiotherapy+Delayed Surgical Excision of Ductal Carcinoma
The purpose of this pilot study is to compare by pathological findings surgical excision versus neoadjuvant radiotherapy followed by delayed surgical excision of ductal carcinoma in situ (DCIS)
- Trial name
- NORDIS (NCT03909282)
- Testing
- Lumpectomy, Partial breast irradiation prior to surgery
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Lung Cancer
Personalized Accelerated ChEmoRadiation (PACER) for Lung Cancer
The purpose of this study is to examine the use of hypofractionated accelerated radiation therapy (HART) to treat locally advanced lung cancer. Depending on the location and size of the tumor.
- Trial name
- NCT06080061
- Testing
- Hypofractionated accelerated radiation therapy
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Liver Failure
TLI- and ATG-Enabled Minimization Protocol in Liver Transplantation
The unmet medical need in solid organ transplantation is to eliminate the lifelong requirement of powerful immune suppression drug combinations with their attendant side effects, and to prevent immune mediated rejection of the…
- Trial name
- TEMPO-LT (NCT07634562)
- Testing
- Anti-Thymocyte Globulin, ATG (Rabbit), Total lymphoid irradiation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Colorectal Cancer
Advocacy, Partnership, Outreach, and Yielding Optimized Care for Oncology Patients
This study is a pilot feasibility randomized trial involving newly diagnosed colorectal cancer (CRC) patients who identify as Latinx.
- Trial name
- NCT07403981
- Testing
- CHW/P Navigator Support, Social Services Resource List
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University