Clinical trials: open to volunteers, sponsored by M.D. Anderson Cancer Center
DIGEST, Evidence Based Measurement
Dissemination and Implementation of DIGEST™ as an Evidence-based Measurement Tool for Dysphagia: A Randomized Implementation Trial
To improve swallowing outcomes in cancer through clinical implementation of the Dynamic Imaging Grade of Swallowing Toxicity (DIGEST™) as an evidence-based practice (EBP) tool to grade pharyngeal dysphagia (difficulty swallowing)…
- Conditions
- DIGEST, Evidence Based Measurement, Dysphagia, Randomized Implementation
- Trial name
- NCT07283653
- Testing
- No intervention, DIGEST Training Program, DIGEST Training + Practice Facilitation
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- M.D. Anderson Cancer Center
Brain Metastases
Phase II Trial of the PARP Inhibitor Niraparib and PD-1 Inhibitor Dostarlimab in Patients With Advanced Cancers With Active Progressing Brain Metastases (STARLET)
To learn if the combination of niraparib and dostarlimab can help to control advanced cancer that has spread to the brain.
- Trial name
- NCT05700721
- Testing
- Niraparib, Dostarlimab
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- M.D. Anderson Cancer Center
Lung Cancer
Adaptation and Pilot Testing of a Lung Cancer Screening Decision Aid for Patients From a Safety-Net Healthcare System
The goal of the study is to adapt and test a participant decision aid about lung cancer screening for use with patients in theHarris Health System (HHS).
- Trial name
- NCT07382557
- Testing
- Surveys, Focus groups, Cognitive Interviews
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Bone Metastases
A Phase III Randomized Trial Comparing Stereotactic Body Radiation Therapy (SBRT) vs Conventional Palliative Radiation Therapy for Painful Bone Metastases
To compare increasing doses and different treatment schedules of stereotactic body radiation therapy (SBRT) against standard treatment scheduling.
- Trial name
- NCT06065449
- Testing
- Radiation Therapy
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Delirium, Epileptics
Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy
To examine the effects of haloperidol, chlorpromazine, valproic acid and placebo, in conjunction with standardized non-pharmacologic interventions, in the first line treatment of agitated delirium in hospitalized patients with…
- Conditions
- Delirium, Epileptics, Neuroleptics
- Trial name
- NCT05431595
- Testing
- Haloperidol, Chlorpromazine, Valproate
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Pancreatitis
Prospective Evaluation of Chronic Pancreatitis for Epidemiologic and Translational Studies
The Coordinating and Data Management Center (CDMC) at MD Anderson Cancer will be responsible for the coordination and data management for the Prospective Evaluation of Chronic Pancreatitis for Epidemiologic and Translational…
- Trial name
- NCT03099850
- Testing
- Data Management and Monitoring
- Where
- United States
- Volunteers
- 2,345 people
- Sponsor
- M.D. Anderson Cancer Center
Lung Cancer, Cancer of Thorax
PROSPECT - Profiling of Resistance Patterns & Oncogenic Signaling Pathways in Evaluation of Cancers of the Thorax and Therapeutic Target Identification
In this Project, we will use therapeutic target -focused (TTF) profiling, genome-wide mRNA profiling and assessments of tumor phosphopeptides and DNA that are shed into the blood stream to define how various molecular factors…
- Trial name
- NCT05049837
- Testing
- Group Specific Aim 1, Group Specific Aim 2, Group Specific Aim 3
- Where
- United States
- Volunteers
- 7,200 people
- Sponsor
- M.D. Anderson Cancer Center
Lung Cancer Screening
CPRIT: Patient Adherence to Lung Cancer Screening
To understand participants' barriers to lung cancer screening and their experience with scheduling lung cancer screening.
- Trial name
- NCT06872723
- Testing
- Lung Cancer Screening
- Where
- United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer
Older Men's Decision Making About Active Surveillance for Prostate Cancer - Aim 3: Decision Aid Efficacy Testing
This protocol describes pilot testing of an educational shared decision-making intervention to help men with localized prostate cancer make decisions with their health care providers about if and when to de-escalate surveillance…
- Trial name
- NCT06785441
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- M.D. Anderson Cancer Center
Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Adenocarcinoma
Modifying Metabolic Syndrome and Cardiovascular Risk for Prostate Cancer Patients on ADT Using a Risk Factor Modification Program and Continuous Fitbit Monitoring
This phase II trial studies how well an exercise program and continuous Fitbit monitoring work for managing metabolic syndrome and cardiovascular disease risk in patients with prostate cancer that has spread to other places in…
- Conditions
- Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8
- Trial name
- NCT05054296
- Testing
- Educational Intervention, Exercise Intervention, FitBit
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- M.D. Anderson Cancer Center
Endocrine Disease
Comprehensive Data Collection and Follow-Up for Patients With Thyroid, Parathyroid and Adrenal Disease
The goal of this data review study is to collect data to learn more about thyroid, parathyroid, and adrenal disease.
- Trial name
- NCT03050762
- Testing
- Data Collection, Follow Up
- Where
- United States
- Volunteers
- 15,000 people
- Sponsor
- M.D. Anderson Cancer Center
Multiple Endocrine Neoplasia
Metabolomics and Genetic Diagnosing Pancreatic Neuroendocrine Tumors in MEN1 Patients
Objectives: The aim of the present study is to assess the significance of metabolomics and genetics in diagnosing and survival evaluation for pNET in the periodic follow-up of MEN1 patients.
- Trial name
- NCT03048266
- Where
- United States
- Volunteers
- 629 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Colon Polyps
Prospective Study of Colon Serrated Polyps
With this study, the investigators plan to review the clinical, epidemiology, pathology, and endoscopic features of colon serrated lesions as well as outcome of endoscopic resection of these lesions.
- Trial name
- NCT02332785
- Testing
- Data Collection
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- M.D. Anderson Cancer Center
Cord Blood Stem Cell Transplantation, Cord Blood Transplantation
The Collection and Storage of Umbilical Cord Blood for Transplantation
The goal of this study is to collect blood samples from the umbilical cords of newborn babies, as soon as they are delivered, and to place these samples in the MD Anderson Cord Blood Bank.
- Conditions
- Cord Blood Stem Cell Transplantation, Cord Blood Transplantation, Hematopoietic Stem Cell Transplantation
- Trial name
- NCT01728545
- Where
- United States
- Volunteers
- 250,000 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center