Clinical trials: sponsored by Copenhagen University Hospital, Rigshospitalet
Oxidative Stress
Study of the Ability of Clarithromycin to Induce Oxidative Stress
The purpose of the study is to examine whether Klacid® (Clarithromycin) will induce oxidative stress (stress from oxygen) in healthy subjects.
- Trial name
- CLAROX (NCT00707330)
- Testing
- Clarithromycin
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Postoperative Constipation
Prevention of Constipation: Systematic Nursing Interventions to Reduce Postoperative Constipation After Thoracic Surgery
The purpose of the study is to reduce the incidence of postoperative constipation by systematic nurse assessment, interventions and evaluation, in the first month after thoracic surgery.
- Trial name
- NCT00364169
- Testing
- Degree of constipation
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Malignant Melanoma
Sentinel Node With Ultrasound Contrast in Melanoma
The purpose is to evaluate,in 20 patients, if the sentinel node(s) in melanoma can be detected by lymph contrast ultrasound. In comparing the patients will also get lymph-scintigraphy and sentinel node detection wiht blue dye.
- Trial name
- NCT00370136
- Testing
- ultrasound contrast
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cervical Cancer
New Indications for Ultrasound in the Staging of Cervical Cancer
The purpose is to investigate and evaluate two new diagnostic methods using ultrasound in the staging of cervical cancer. 1. 3-D-ultrasound of the tumour to estimate its volume and local spread 2.
- Trial name
- NCT00451945
- Testing
- biopsy, 3d-ultrasound and fusion of UL and PET/CT
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Autoimmune Hepatitis
Mycophenolate vs Azathioprin in Autoimmune Hepatitis
A study with 20 de novo patients with autoimmune hepatitis, 10 receiving azathioprin and 10 receiving mycophenolat mofetil.
- Trial name
- NCT00687180
- Testing
- Treatment with mycophenolat mofetil, Treatment with azathioprin
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Myocardial Infarction, Cardiac Arrest
Troponin-T for Detection of Perioperative Cardiovascular Events
We will conduct a prospective cohort study evaluating the incidence of and optimal risk estimation model for major perioperative cardiovascular events in consecutive patients undergoing noncardiac surgery at the 'Herlev…
- Trial name
- VISION-pilot (NCT00443989)
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Non-Small Cell Lung Cancer
Neoadjuvant Chemotherapy Plus/Minus Surgery in Non-Small-Cell Lung Cancer (NSCLC) Stage IIIA/N2
Hypothesis is that surgery is of benefit in locally advanced NSCLC with N2 disease. Patients are randomised to surgery or not.
- Trial name
- NCT00273494
- Testing
- Surgery
- Where
- Denmark
- Volunteers
- 406 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Myocardial Infarction
Efficacy and Safety of Prehospital Administration of Bivalirudin in STEMI Patients
The purpose of this study is to describe the efficacy and safety of prehospital administration of bivalirudin, as a substitute for heparin, in patients with acute myocardial infarction redirected for primary angioplasty bypassing…
- Trial name
- NCT00391326
- Where
- 2 sites in Denmark
- Volunteers
- 102 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Allogeneic Stem Cell Transplantation, Leukemia
Multimodal Intervention in Allogeneic Stem Cell Transplantation
Objective: To evaluate the feasibility and safety of a 4-6 weeks exercise - psycho-educational intervention in patients undergoing allogeneic stem cell transplantation (allo-HCST).
- Trial name
- NCT00427115
- Testing
- Multimodal exercise and psychosocial program
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Healthy, Type 2 Diabetes
Study of Gene Activity in Fat and Muscle in Diabetics and Healthy Controls
The aim of the present protocol is to study gene activity in fat and muscle tissue in type 2 diabetics and healthy volunteers after injection of E.
- Conditions
- Healthy, Type 2 Diabetes, Endotoxemia
- Trial name
- NCT00412906
- Testing
- Escherichia Coli Endotoxin
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Neuromuscular Blockade
The Precision and Arm-to-Arm Variation of Mechanomyography and Acceleromyography for Monitoring of Neuromuscular Block
The purpose of the study is the examine the precision of acceleromyography and mechanomyography during recovery from a neuromuscular blocking agent and to examine whether there is any difference in monitoring block at the…
- Trial name
- NCT00472121
- Testing
- TOF-Watch SX (neuromuscular monitor)
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Neuromuscular Blockade
Comparison of Acceleromyography (AMG) and Mechanomyography (MMG) for Establishing Potency of Neuromuscular Blocking Agents
The purpose of this study was to compare two methods for neuromuscular monitoring, acceleromyography and mechanomyography for establishing the dose-response relationship and the potency of a neuromuscular blocking agent using…
- Trial name
- NCT00660413
- Testing
- TOF-Watch SX (Acceleromyography)
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Neuromuscular Blockade
Performance of Acceleromyography With and Without Preload
The purpose of this study is to examine the precision, bias and limits of agreement when monitoring the neuromuscular block with acceleromyography with and without preload and compare the method to the gold standard…
- Trial name
- NCT00226018
- Testing
- Hand Adapter (Organon, Oss, the Netherlands)
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Heart Disease, Cardiovascular Disease
Best Bypass Surgery (BBS) Trial
There is evidence linking cardiopulmonary bypass to negative side effects when used for coronary artery bypass grafting. Coronary artery bypass grafting can be performed without the use of cardiopulmonary bypass.
- Trial name
- NCT00120991
- Testing
- Coronary artery bypass grafting
- Where
- Denmark
- Volunteers
- 341 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Coronary Arteriosclerosis, Ischemic Heart Disease
Copenhagen Arterial Revascularization Randomized Patency and Outcome Trial
There is a remarkable lack of randomized trials concerning the potential benefit of using arterial conduits for coronary bypass surgery. This is the purpose of the present trial.
- Conditions
- Coronary Arteriosclerosis, Ischemic Heart Disease, Angina Pectoris
- Trial name
- CARRPO (NCT00159991)
- Testing
- Total arterial revascularization, Conventional revascularization
- Where
- Denmark
- Volunteers
- 331 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Primary Hyperalgesia
Sensory Function After Wound Instillation of Capsaicin
The use of capsaicin as a potential analgesic drug for postoperative pain relies on the ability of capsaicin to induce membrane lysis of c-nerve fibers.
- Trial name
- NCT00583180
- Testing
- Capsaicin
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Eisenmenger Syndrome
Combination Treatment With Bosentan and Sildenafil to Patients With Eisenmengers Syndrome
The purpose of this study is to investigate if combination treatment with Bosentan and Sildenafil to patients with Eisenmenger syndrome is beneficial.
- Trial name
- NCT00303004
- Testing
- Bosentan and Sildenafil
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Systemic Inflammatory Response Syndrome, Coronary Arteriosclerosis
Cleansing of Suction Blood in Cardiac Surgery for Reduced Inflammatory Response
Cardiac surgery using heart and lung machine produces an inflammatory reaction in the body. This leads in few percent of cases to heart, lung, and kidney disturbances that potentially causes death.
- Trial name
- NCT00159926
- Testing
- Cell saver, No cell saver
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Depression
Comparison of Thiopental and Propofol as Anaesteticum During ECT
Electroconvulsive therapy is the most effective treatment in severe depression and the effect is related to the generalized seizure induced by the treatment. General anesthesia is used during the treatment.
- Trial name
- NCT00379886
- Testing
- Propofol Thiopental
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Infertility, In Vitro Fertilization
Nordic Luveris Study
To study whether addition of human LH hormone (Luveris) during the final days of stimulation with recombinant FSH (Gonal-f) for controlled ovarian stimulation will be of benefit for patients undergoing in vitro fertilisation.
- Trial name
- NCT00553293
- Testing
- recombinant luteinizing hormone (Luveris), recombinant follicle stimulating hormone (Gonal-f)
- Where
- Denmark
- Volunteers
- 526 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
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