Clinical trials: open to volunteers, sponsored by China-Japan Friendship Hospital
Heart Failure With Reduced Ejection Fraction, Iron Deficiency
The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life(COREVIVE-HFrEF)
This study will address whether the additional use of Ferric Derisomaltose on top of standard care will improve exercise capacity and quality of life in patients with acute heart failure and iron deficiency.
- Conditions
- Heart Failure With Reduced Ejection Fraction, Iron Deficiency, Acute Heart Failure
- Trial name
- COREVIVE-HFrEF (NCT05971732)
- Testing
- Ferric derisomaltose
- Where
- China
- Volunteers
- 146 people
- Sponsor
- China-Japan Friendship Hospital
Heart Failure With Preserved Ejection Fraction, Iron Deficiencies
The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life
This study will address whether the additional use of Ferric Derisomaltose on top of standard care will improve exercise capacity and quality of life in patients with acute heart failure and iron deficiency.
- Conditions
- Heart Failure With Preserved Ejection Fraction, Iron Deficiencies, Acute Heart Failure
- Trial name
- COREVIVE-HFpEF (NCT05991128)
- Testing
- Ferric derisomaltose
- Where
- China
- Volunteers
- 170 people
- Sponsor
- China-Japan Friendship Hospital
Immune Checkpoint Inhibitors Related Myocarditis
Baduanjin Rehabilitation for Functional Restoration in ICI-Associated Myocarditis
Immunotherapy has become a cornerstone in oncology; however, managing its associated adverse events poses a significant clinical challenge.
- Trial name
- NCT07280429
- Testing
- rehabilitation protocol
- Where
- China
- Volunteers
- 60 people
- Sponsor
- China-Japan Friendship Hospital
Heart Failure, Iron Deficiency
The Effects of Low-Dose Versus High-Dose Intravenous IRON Therapy With Ferric DerisomaltOSE in Patients With Chronic Heart Failure and Iron Deficiency
This study will address whether intravenous (IV) iron repletion with a more intensive target will provide greater benefits in improving exercise capacity for patients with chronic heart failure and iron deficiency.
- Trial name
- IRONDOSE (NCT06427343)
- Testing
- High-dose ferric derisomaltose, Low-dose ferric derisomaltose
- Where
- China
- Volunteers
- 114 people
- Sponsor
- China-Japan Friendship Hospital
Immune Checkpoint Inhibitor-Related Myocarditis
Monitoring and Rehabilitation for ICIACI Rehabilitation：A Cohort Study
Immune checkpoint inhibitor-associated cardiac injury (ICIACI) is a low-incidence but highly fatal adverse event. A significant knowledge gap exists regarding the disease characteristics and recovery status of patients during the…
- Trial name
- NCT07278817
- Volunteers
- 340 people
- Sponsor
- China-Japan Friendship Hospital
Sedentary Lifestyle, Behavioral Intervention
Effects of Baduanjin Exercise on Improving Health in Sedentary Young and Middle-Aged Adults
The goal of this clinical trial is to learn if a 12-week Baduanjin exercise program can improve health in sedentary young and middle-aged adults. The main questions it aims to answer are: 1.
- Trial name
- NCT07482995
- Testing
- Baduanjin exercise, General Health Education
- Where
- China
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- China-Japan Friendship Hospital
Heart Failure
Novel Wearable Device for Heart Failure Management
Heart failure (HF) is a major cardiovascular disease with high readmission and mortality rate. A wearable device that could remotely monitor and detect the worsening HF early before the symptoms appear will help reduce HF…
- Trial name
- NCT05642650
- Testing
- novel wearable device
- Volunteers
- 108 people
- Sponsor
- China-Japan Friendship Hospital
Heart Failure
SHengXIaN-QuYu DEcoction in Heart Failure With Reduced and Mildly Reduced Ejection Fraction
The purpose of this study is to conduct a multicenter, randomized clinical trial to evaluate the effect of "ShengXian-QuYu Decoction" on quality of life , symptoms, and biomarkers in heart failure patients with reduced and mildly…
- Trial name
- SHINE-HF (NCT05583773)
- Testing
- ShengXian-QuYu Decoction
- Where
- 26 sites in China
- Volunteers
- 336 people
- Sponsor
- China-Japan Friendship Hospital
Chronic Thromboembolic Pulmonary Hypertension (CTEPH), Acute Pulmonary Embolism (PE)
CTEPH Differential Diagnosis Assisted by Enhanced Large Language Model Support
This randomized controlled trial aims to evaluate whether a locked large language model (LLM)-based clinical decision support system improves the differential diagnosis of pulmonary artery filling defects among physicians who do…
- Conditions
- Chronic Thromboembolic Pulmonary Hypertension (CTEPH), Acute Pulmonary Embolism (PE), Pulmonary Artery Sarcoma
- Trial name
- NCT07902011
- Testing
- Locked CTEPH-LLM Diagnostic Decision Support
- Where
- China
- Volunteers
- 60 people
- Sponsor
- China-Japan Friendship Hospital
Knee Osteoarthritis, Replacement, Knee
Exploration of Appropriate BIS Range and Propofol Effect-site Concentration During Total Intravenous Anesthesia With Concomitant Adjuvants.
The goal of this clinical trial is to determine the appropriate Bispectral Index (BIS) range and propofol effect-site concentration required to maintain adequate anesthesia depth during total intravenous anesthesia (TIVA)…
- Conditions
- Knee Osteoarthritis, Replacement, Knee, Elective Surgical Patients, ASA Class I/II Patients
- Trial name
- NCT07736352
- Testing
- Propofol + Remifentanil +Midazolam, Propofol + Remifentanil + Dexmedetomidine, Propofol + Remifentanil + Esketamine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China-Japan Friendship Hospital
Depth of Anesthesia Monitoring, BIS-EEG
The Effects of Midazolam, Dexmedetomidine, and Esketamine on Bispectral Index and Raw Electroencephalogram in Patients Under Propofol-Remifentanil Baseline Anesthesia
This prospective, single-center, randomized interventional study aims to investigate the effects of commonly used adjunct anesthetic drugs on the Bispectral Index (BIS) and electroencephalographic (EEG) activity during total…
- Trial name
- NCT07699523
- Testing
- Midazolam, Dexmedetomidine, Esketamine
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- China-Japan Friendship Hospital
Omentopexy, Sleeve Gastrectomy
De Novo Gastroesophageal Reflux Disease After Sleeve Gastrectomy With and Without Omentopexy
The goal of this clinical trial is to compare the effects of sleeve gastrectomy with and without omentopexy on gastroesophageal reflux disease (GERD) in patients with obesity.
- Conditions
- Omentopexy, Sleeve Gastrectomy, Gastroesophageal Reflux Disease
- Trial name
- NCT07854613
- Testing
- Sleeve Gastrectomy With Omentopexy, Sleeve Gastrectomy Without Omentopexy
- Where
- China
- Volunteers
- 140 people
- Sponsor
- China-Japan Friendship Hospital
Ankylosing Spondylitis
A Randomized Trial of Ultrasound-Guided Acupotomy for Ankylosing Spondylitis
This study employs a randomized controlled trial methodology to systematically evaluate the efficacy and safety of a modified acupotomy technique in the treatment of ankylosing spondylitis.
- Trial name
- UGA-AS RCT (NCT07578220)
- Testing
- Ultrasound-guided acupotomy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- China-Japan Friendship Hospital
Chronic Obstructive Pulmonary Disease
Long-term Effects of Endobronchial Valve Implantation on Cardiac Function and Skeletal Muscle Function
The goal of this type of study: clinical trial is to evaluate the effect of bronchial valve implantation on cardiac function and skeletal muscle function in Chronic Obstructive Pulmonary Disease.
- Trial name
- NCT05775588
- Testing
- Lung volume reduction surgery with endobronchial valve implantation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China-Japan Friendship Hospital
Obesity, Robot Surgery
Study on the Safety and Efficacy of Domestic Single-Port Robot-Assisted Metabolic Bariatric Surgery.
This study aims to obtain short-term clinical results on the safety and efficacy of single-port robot-assisted metabolic weight loss surgery, and to provide further evidence for the clinical promotion of single-port robot systems.
- Trial name
- NCT07335731
- Testing
- Robot-assisted single-port bariatric surgery
- Where
- China
- Volunteers
- 50 people
- Sponsor
- China-Japan Friendship Hospital
Obesity
Bariatric Surgery Combined With GLP-1RA: A Multicenter Study.
Obese patients exhibit considerable heterogeneity and complex comorbidities, making long-term effective management challenging with single therapies.
- Trial name
- BS-GLP (NCT07732738)
- Testing
- BS-GLP1RA group, BS group
- Where
- 7 sites in China
- Volunteers
- 400 people
- Sponsor
- China-Japan Friendship Hospital
Intestinal Flora, Anorectal Diseases
Research on the Efficacy and Mechanism of Shouhui Tongbian Capsules in Treating Postoperative Constipation of Benign Anal and Rectal Diseases Based on Gut Microbiota Analysis
The goal of this clinical trial is to evaluate whether Shouhui Tongbian Capsule can improve postoperative constipation in adults aged 18 to 75 years after surgery for benign anorectal diseases, including hemorrhoids and anal…
- Conditions
- Intestinal Flora, Anorectal Diseases, Surgery, Constipation
- Trial name
- NCT07648394
- Testing
- Shouhui Tongbian Capsules, Lactulose Oral Solution Control Group
- Where
- China
- Volunteers
- 120 people
- Sponsor
- China-Japan Friendship Hospital
Emphysema
Endobronchial Silicone Valve for Patients With Emphysema
The purpose of this research is to evaluate the efficacy and safety of endobronchial silicone valve in patients with severe emphysema.
- Trial name
- NCT07097896
- Testing
- ESV, Optimal Medical Management (OMM)
- Where
- China
- Volunteers
- 147 people
- Sponsor
- China-Japan Friendship Hospital
COPD
Effect of Oral Astaxanthin Formula on Pulmonary Rehabilitation in Patients With COPD
The goal of this clinical trial is to investigate whether an astaxanthin-based dietary supplement combined with a pulmonary rehabilitation training program could improve exercise capacity in patients with COPD.
- Trial name
- NCT07684391
- Testing
- Astaxanthin, Pulmonary rehabilitation training
- Volunteers
- 140 people
- Sponsor
- China-Japan Friendship Hospital
ESRD (End-Stage Renal Disease), Maintenance Hemodialysis
Efficacy of pHA130 Hemoadsorption on Protein-Bound Uremic Toxins and Quality of Life in Kidney Failure
Patients on maintenance hemodialysis (MHD) face a high risk of cardiovascular mortality and reduced quality of life. Conventional high-flux hemodialysis (HD) is the standard of care but has limited efficacy in clearing…
- Trial name
- PHOENIX (NCT07656168)
- Testing
- pHA130 Hemoadsorption Cartridge, High-flux Hemodialyzer
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China-Japan Friendship Hospital