Clinical trials: app or software or digital or wearable or device or sensor, open to volunteers
- Drug or intervention app OR software OR digital OR wearable OR device OR sensor
- Status Open to volunteers
Chronic Neck Pain With Mobility Deficits, Chronic Neck Pain With Mobility Deficits (> 3 Months)
EFFECT OF MULLIGAN CERVICAL SUSTAINED NATURAL APOPHYSEAL GLIDE ON POSTURAL STABILITY IN PATIENTS WITH CHRONIC NECK PAIN
This study seeks to address the identified research gap by objectively investigating the effect of Mulligan Cervical SNAGs on postural stability in individuals with chronic neck pain and mobility impairments.
- Trial name
- SNAG Mulligan (NCT07673575)
- Testing
- 1- The Biodex Balance System (BBS), 2-The Numerical Pain Rating Scale (NPRS), 3- The Neck Disability Index (Arabic version) for functional disability
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Menna Allah Ahmed Marei Elnaggar
Impingement Syndrome, Impingement Shoulder
PMT Versus IASTM in Subacromial Impingement Syndrome
This assessor-blinded, three-arm, parallel-group randomized controlled trial will investigate the additional effects of percussion massage therapy and instrument-assisted soft tissue mobilization in individuals with subacromial…
- Conditions
- Impingement Syndrome, Impingement Shoulder, Shoulder Pain
- Trial name
- NCT07756203
- Testing
- Percussion massage therapy device, Instrument-assisted soft tissue mobilization device, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Emre DANSUK
Hypertension
Effectiveness and Cost-Effectiveness of a Digital Care Pathway and Asynchronous Communication for Patients With Hypertension
The goal of this clinical trial is to learn if digital care pathway (DCP) and digital non-real-time messaging, in other words, asynchronous communication (AC) with nurse works to treat high blood pressure in adults in primary…
- Trial name
- DEPTH (NCT07812350)
- Testing
- Digital care pathway for hypertension, Asynchronous communication with nurse
- Where
- 6 sites in Finland
- Volunteers
- 600 people
- Sponsor
- Wellbeing Services County of Pirkanmaa
Depressive Disorder, Major Depressive Disorder, Suicidal Ideation
Evaluation of a Multi-Layered Digital Phenotyping, Digital Safety Plan, and Pharmacogenomic Intervention for Suicide Prevention in Adults With Depression
The goal of this clinical trial is to learn if a multi-layered digital and pharmacogenomic intervention works to prevent suicide re-attempts in adults with depression.
- Conditions
- Depressive Disorder, Major Depressive Disorder, Suicidal Ideation, Suicide, Attempted, Suicide Prevention
- Trial name
- SMARTomicS (NCT07885722)
- Testing
- Digital Monitoring (Active/Passive EMA), Ecological Momentary Intervention (EMI) via Digital Safety Plan, Pharmacogenetic-Guided Care and Therapeutic Drug Monitoring
- Where
- Spain
- Volunteers
- 525 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Aortic Aneurysm, Aortic Dissection
A Novel Wire-Reinforced Fenestration of a Hybrid Frozen Elephant Trunk Device for Supra-Aortic Branch Vessel Stenting During Aortic Arch Replacement
The goal of this prospective, non-randomized trial is to determine the safety and technical success of a novel modification to a U.S.
- Conditions
- Aortic Aneurysm, Aortic Dissection, Penetrating Aortic Ulcer (PAU), Aortic Pseudoaneurysm
- Trial name
- SA-FET (NCT07885865)
- Testing
- Modified Supra-Aortic Frozen Elephant Trunk (SA-FET) Device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Maryland, Baltimore
Medical Rehabilitation
Impact of Functional Rehabilitation on Digital Independence: Validation of a Novel Smartphone Use Score as an Indicator of Discharge Readiness in Medical Care and Rehabilitation.
Patients' independence in Medical Care and Rehabilitation (SMR) settings is typically assessed using functional scales such as the Barthel Index.
- Trial name
- ICARE (NCT07886021)
- Testing
- TSHN-SMR (Test Standardisé d'Habileté Numérique sur Dispositif Dédié), Barthel scale
- Volunteers
- 150 people
- Sponsor
- Artois Private Hospital
Stroke
Inpatient Stroke Recovery Using Sensors
This observational trial seeks to assess the feasibility of using non-invasive, portable, real-time body-worn sensors to continuously monitor, quantify, and interpret recovery during inpatient treatment of stroke
- Trial name
- NCT04219670
- Testing
- Wearable sensors
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Early-Onset Alzheimer Disease
A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD
The purpose of this study is to evaluate the safety, tolerability, pharmacodynamics (PD) and pharmacokinetics (PK) of a single dose and multiple doses of ALN-APP administered by intrathecal (IT) injection in adult patients with…
- Trial name
- NCT05231785
- Testing
- ALN-APP
- Where
- 8 sites in United States, Canada and 2 more
- Volunteers
- 60 people
- Sponsor
- Alnylam Pharmaceuticals
Benign Prostate Obstruction (BPO)
SteamOne - Prospective Database for Rezum Water Vapor Therapy of the Prostate
This study is to assess the clinical data of Rezum (water vapor therapy) in patients with BPO (benign prostate obstruction) and male LUTS (lower urinary tract symptoms) in terms of efficacy, durability and safety in a large…
- Trial name
- SteamOne (NCT05495633)
- Testing
- Collection and evaluation of clinical (CROMs) and patient-reported outcomes (PROMs), Analysis of uroflowmetry data by EmanoFlow Mobile Application (App) and Emano Clinic Portal
- Where
- 19 sites in Austria, Germany and 1 more
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Genital Diseases, Female, Ectopic Pregnancy
Randomized Study of a Dematerialized Management for Post-Emergency Gynecological Follow-Up
The GYNAB study aims to compare patient satisfaction and clinical outcomes between dematerialized post-emergency gynecological follow-up using a connected health app and traditional in-person follow-up. Conducted by Drs.
- Conditions
- Genital Diseases, Female, Ectopic Pregnancy, Uncertain Viability of Pregnancy, Abortion, Missed
- Trial name
- GYNAB (NCT06615843)
- Testing
- Participants will receive post-emergency gynecological follow-up at home using a connected health app
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intracerebral Hemorrhage, Mesenchymal Stem Cell
Stem Cell Therapy for Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) is a common condition with high morbidity, mortality, and disability. The current treatments for ICH primarily include surgical and pharmacological interventions.
- Trial name
- NCT06862388
- Testing
- Device: Phase Ⅰ Dose Level 1, Device: Phase Ⅰ Dose Level 2, Device: Phase Ⅰ Dose Level 3
- Where
- China
- Volunteers
- 39 people
- Sponsor
- Tang Zhouping
Prolonged Grief Disorder (PGD)
Technology-supported Interventions for Prolonged Grief Disorder (PGD)
The main aim of this project is to test the efficacy of two formats of delivering an internet- based treatment(GROw) for Prolonged Grief Disorder (PGD) in order to enhance treatment adherence: in a blended format (that combines…
- Trial name
- NCT06932120
- Testing
- Internet-based treatment (GROw) combined with face-to-face videoconferencing sessions with a therapist in BF-GROw group, Internet-based treatment (GROw) supported by the App developed which contains the EMA and EMI tools in iGROw group.
- Where
- 2 sites in Spain
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Universitat Jaume I
End-Stage Renal Disease, Chronic Kidney Diseases
Technology-enabled Social Network Intervention to Increase Live Donor Kidney Transplantation
The study is a 2-arm randomized controlled trial among patients referred for kidney transplant evaluation at a single transplant center to compare the effects of a digital-analog intervention to increase living-donor kidney…
- Conditions
- End-Stage Renal Disease, Chronic Kidney Diseases, Kidney Transplant, Living Kidney Donor
- Trial name
- KT-CONNECT (NCT07072767)
- Testing
- Digital education outreach intervention for kidney transplant access and human guide, Digital education outreach intervention for kidney transplant access only (unguided)
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- State University of New York at Buffalo
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Induction and Consolidation With Fludarabine, Cytarabine, Idarubicin, and Venetoclax for the Treatment of Acute Myeloid Leukemia
This phase II trial compares induction and consolidation therapy with fludarabine, cytarabine, idarubicin, and venetoclax to cytarabine and daunorubicin induction and cytarabine consolidation for the treatment of acute myeloid…
- Trial name
- NCT07228273
- Testing
- Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- OHSU Knight Cancer Institute
Autism Spectrum Disorder (ASD
Monitoring Daily Mobility in Children With Autism
Children with autism spectrum disorder (ASD) often show motor abnormalities and sleep disturbances that affect behavior, learning, and family quality of life.
- Trial name
- SIMBA (NCT07519369)
- Testing
- placement of a wearable wrist sensor
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Benign Prostatic Hyperplasia (BPH)
To Establish the Safety and Effectiveness of the ALPFA GRAIL PFA System for Treating Symptomatic Benign Prostate Hyperplasia (BPH) Also Known as an Enlarged Prostate.
The main goal of this study is to evaluate the ALPFA GRAIL™ Pulsed Field Ablation (PFA) System for treatment of enlarged prostate (BPH) symptoms.
- Trial name
- REBOUND (NCT07592299)
- Testing
- Treatment Device: The ALPFA Medical (ALPFA) GRAIL™ Pulsed Field Ablation (PFA) System
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- ALPFA Medical
Cardiovascular Health Status, Smoking Status
Effectiveness and Implementation Evaluation of NeoMayor for Improving Cardiovascular Health in Chilean Older Adults
This study aims to evaluate the effectiveness and implementation of NeoMayor, a mobile health (mHealth) intervention designed to improve cardiovascular health among older adults at elevated cardiovascular risk in Chile.
- Conditions
- Cardiovascular Health Status, Smoking Status, Physical Activity, Diet Quality
- Trial name
- NEOMAYOR (NCT07633392)
- Testing
- NeoMayor App, Wearable Device Support, Human Health Coach Support
- Where
- 2 sites in Chile
- Volunteers
- 240 people
- Sponsor
- University of Chile
Pancreatic Fluid Collections, Biliary Obstruction
EUS Procedures Using RIVOS™ EUS Access Device
This is a prospective study of patients undergoing EUS procedures using the RIVOS™ EUS access device.
- Conditions
- Pancreatic Fluid Collections, Biliary Obstruction, Pancreatic Duct Obstruction, Chronic Pancreatitis
- Trial name
- NCT07696572
- Testing
- EUS-guided intervention using the RIVOS™ EUS access device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Orlando Health, Inc.
Breast Cancer, Alcohol Drinking
Implementing a Digital Alcohol Intervention to Raise Women's Awareness of Alcohol-related Breast Cancer Risk During Routine Screening Visits
This study is a single-arm feasibility trial evaluating a digital behavioral intervention designed to increase women's awareness of the relationship between alcohol use and breast cancer risk during routine breast cancer…
- Trial name
- NCT07799467
- Testing
- Sobriety Digital Intervention
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Miami
Acute Myocardial Infarction (AMI), Asystole
SPIKE FLOW Endocardial Lead Safety and Performance Study
The objective of this study is to assess the safety and performance of the SPIKE FLOW endocardial lead. Primary objectives are to assess: safety in terms of freedom from Serious Adverse Events(SADEs); performance in terms of Mean…
- Conditions
- Acute Myocardial Infarction (AMI), Asystole, Bradycardia, AV Block
- Trial name
- SPIKE FLOW (NCT07820072)
- Testing
- Lead insertion, lead removal
- Where
- 3 sites in Italy
- Volunteers
- 131 people
- Sponsor
- FIAB SpA