Clinical trials: adjuvant therapy
Melanoma (Skin)
Vaccine Therapy in Treating Patients With Primary Stage II Melanoma
RATIONALE: Vaccines may make the body build an immune response to kill tumor cells. It is not yet known whether vaccine therapy is more effective than observation alone for melanoma.
- Trial name
- NCT00005052
- Testing
- GM2-KLH vaccine, QS21, adjuvant therapy
- Where
- 80 sites in Australia, Belgium and 16 more
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Breast Cancer
Combination Chemotherapy in Treating Women With Resected Breast Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and giving them after surgery may kill any tumor cells remaining after surgery.
- Trial name
- NCT00033683
- Testing
- CMF regimen, cyclophosphamide, docetaxel
- Where
- 69 sites in Belgium, United Kingdom
- Sponsor
- Institute of Cancer Research, United Kingdom
Brain and Central Nervous System Tumors
Brachytherapy in Treating Patients With Recurrent Malignant Glioma
RATIONALE: Brachytherapy uses radioactive material to kill cancer cells remaining after surgery. PURPOSE: Phase I trial to study the effectiveness of brachytherapy in treating patients who have recurrent malignant glioma.
- Trial name
- NCT00045474
- Testing
- adjuvant therapy, iodine I 125
- Where
- 9 sites in United States
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer
Celecoxib, Leucovorin, Fluorouracil, and Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer
RATIONALE: Drugs used in chemotherapy, such as leucovorin, fluorouracil, and oxaliplatin, use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00072553
- Testing
- celecoxib, fluorouracil, leucovorin calcium
- Where
- France
- Sponsor
- GERCOR - Multidisciplinary Oncology Cooperative Group
Breast Cancer
Adjuvant Radiation Therapy Compared With Observation After Surgery in Treating Women With Estrogen Receptor Positive or Progesterone Receptor Positive Ductal Carcinoma In Situ of the Breast Who Are Receiving Tamoxifen or Anastrozole
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known whether radiation therapy after surgery is effective in preventing a recurrence of ductal carcinoma in situ.
- Trial name
- NCT00077168
- Testing
- anastrozole, tamoxifen citrate, adjuvant therapy
- Where
- 29 sites in United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Lung Cancer
Paclitaxel, Carboplatin, and Radiation Therapy With or Without Adjuvant Paclitaxel and Carboplatin in Treating Patients With Stage II or Stage III Unresectable Non-Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00077220
- Testing
- carboplatin, paclitaxel, adjuvant therapy
- Where
- 68 sites in France
- Sponsor
- GERCOR - Multidisciplinary Oncology Cooperative Group
Colorectal Cancer
Fluorouracil and Irinotecan With or Without Leucovorin Compared With Observation in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer
RATIONALE: Drugs used in chemotherapy, such as irinotecan, leucovorin, and fluorouracil, work in different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00091312
- Testing
- FOLFIRI regimen, fluorouracil, irinotecan hydrochloride
- Where
- 9 sites in Egypt, France and 4 more
- Volunteers
- 1,976 people
- Sponsor
- Federation Francophone de Cancerologie Digestive
Lung Cancer
Celecoxib or Observation After Radiation Therapy and Chemotherapy in Treating Patients With Stage II or Stage III Non-Small Cell Lung Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them…
- Trial name
- NCT00274898
- Testing
- celecoxib, docetaxel, adjuvant therapy
- Where
- 15 sites in France
- Volunteers
- 80 people
- Sponsor
- GERCOR - Multidisciplinary Oncology Cooperative Group
Schizophrenia
Shiatsu Adjuvant Therapy And Placebo For Schizophrenia
In the current study we will study the effect of adding acupressure (shiatsu) to conventional therapy in treating individuals with schizophrenia.
- Trial name
- NCT00788970
- Testing
- Acupressure adjuvant therapy
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Herzog Hospital
Lung Cancer
Vaccine Therapy in Treating Patients Who Are Undergoing Surgery for Stage IB, Stage II, or Stage IIIA Non-Small Cell Lung Cancer
RATIONALE: Vaccines made from a person's tumor cells and white blood cells may make the body build an effective immune response to kill tumor cells.
- Trial name
- NCT00098917
- Testing
- autologous tumor cell vaccine, therapeutic autologous dendritic cells, adjuvant therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Schizophrenia
Reboxetine Adjuvant Therapy for the Treatment of Schizophrenia
30 patients will randomly be selected and will be administered either reboxetine or a placebo. changes in cognition and behavior will be assessed by computer tests and scales during a six week study period.
- Trial name
- NCT00409201
- Testing
- reboxetine adjuvant therapy
- Where
- 2 sites in Israel
- Volunteers
- 30 people
- Sponsor
- Abarbanel Mental Health Center