Clinical trials: Virtual Reality
Positive Affect, Depression
Training Reward Responsiveness Through Virtual Reality
The purpose of this study is to compare the effects of Virtual Reality-Reward Training (VR-RT) with an active control condition, Virtual Reality-Memory Training (VR-MT), on positive affect and other clinical symptoms.
- Trial name
- NCT07219875
- Testing
- Virtual Reality-Reward Training (VR-RT), Virtual Reality-Memory Training (VR-MT)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Wrist Injury, Hand and Upper Limb Trauma
Virtual Reality-based Rehabilitation for Traumatic Hand and Wrist Injuries
This randomized controlled trial aims to evaluate the effectiveness of immersive virtual reality (VR)-based Action Observation Therapy (AOT) as an adjunct to conventional rehabilitation in patients with traumatic wrist and hand…
- Conditions
- Wrist Injury, Hand and Upper Limb Trauma, Hand and Forearm Trauma, Muskuloskeletal Diseases
- Trial name
- AOT-VR-HAND (NCT07633769)
- Testing
- Immersive Virtual Reality Action Observation Therapy, Conventional Rehabilitation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Malaga
Sickle Cell Disease
Virtual Reality for SCD VOC
This randomized pilot study will evaluate the feasibility, tolerability, and preliminary analgesic effect of headset-based virtual reality (VR) interventions for adults with sickle cell disease (SCD) experiencing vaso-occlusive…
- Trial name
- RELIEVE-SCD (NCT07674277)
- Testing
- Passive Immersive 3D Virtual Reality, Active Immersive Interactive 3D Virtual Reality
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Maryland, Baltimore
Type 1 Diabetes
Can Mindfulness and Virtual Reality Reduce Stress in Young Adults With Type 1 Diabetes?
The goal of this study is to learn if Mindfulness-Based Stress Reduction (MBSR) can be delivered using virtual reality (VR) technology to emerging adults (youth 16-20 years old) with type 1 diabetes and high levels of stress…
- Trial name
- MBSR-VR (NCT07793097)
- Testing
- Mindfulness-Based Stress Reduction - Virtual Reality, Stress tip sheet
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Wayne State University
Health College Students
Effects of VR Tai Chi Intervention on Physical Fitness, Anxiety, Depression and Stress Among College Students in Henan, China
Research indicates a substantial increase in the rates of anxiety, depression and stress among college students (Roy, Biswas, \& Sharma, 2025).
- Trial name
- NCT07854821
- Testing
- Virtual Reality-Assisted Tai Chi Training
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Xin Liu
Pain, Anxiety
The Effect of Virtual Reality Use in Cystoscopy on Pain, Anxiety, and Comfort: A Randomized Controlled Trial
This study aims to evaluate the effects of virtual reality (VR) distraction on pain, anxiety, and comfort levels patients undergoing cystoscopy.
- Conditions
- Pain, Anxiety, Patient Comfort, Cystoscopy
- Trial name
- NCT07872137
- Testing
- Virtual Reality Distraction, Standard Care
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Karamanoğlu Mehmetbey University
Obsessive Compulsive Disorder (OCD)
Artificial Intelligence-Powered Virtual Reality Exposure Therapy for OCD in College Students: A Proof-of-Concept Study
This research study is being conducted to study the use of artificial-intelligence powered virtual reality exposure therapy (AI-VRET) to treat college students with obsessive compulsive disorder (OCD).
- Trial name
- AI-VRET (NCT07877363)
- Testing
- Traditional Exposure and Response Prevention (ERP), Artificial Intelligence-Powered Virtual Reality Exposure Therapy (AI-VRET)
- Volunteers
- 24 people
- Sponsor
- University of California, San Diego
Acute Musculoskeletal Pain
Virtual Reality and Standard Care vs. Standard Care Alone for Acute MSK Pain in Geriatric ED Patients
The proposed Virtual Reality as an Adjunct to Pain Management for Geriatric Patients in the ED (VRAP-ED) project will take place in the Emergency Medicine Department at Maimonides Medical Center.
- Trial name
- NCT06685107
- Testing
- Standard of Care Analgesia, Standard of Care Analgesia + Virtual Reality
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Antonios Likourezos
Chronic Nonspecific Low-back Pain, CNSLBP
Effects of Virtual Reality Exergames Versus Spinal Manipulation in Chronic Nonspecific Low Back Pain
The goal of this clinical trial is to compare the acute effects of virtual reality exergames (VR-EXG) and spinal manipulation on pain, kinesiophobia, mood states, functional disability and lumbar range of motion in individuals…
- Trial name
- NCT07876960
- Testing
- Virtual Reality, Spinal manipulation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Coronary Angiography (CAG)
The Effect of Virtual Reality Glasses on Vital Signs and State Anxiety in Patients Undergoing Coronary Angiography
Virtual reality (VR) is an effective, safe, and non-pharmacological intervention for reducing anxiety, with strong scientific evidence and no known adverse effects.
- Trial name
- NCT07032935
- Testing
- Virtual Reality (VR) Intervention
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kutahya Health Sciences University
Chronic Kidney Disease (Stages 3b-5), Hemodialysis
Virtual Reality Versus Intradialytic Neuromuscular Electrical Stimulation on Renin Hormone in Chronic Kidney Patients
Worldwide accelerated advances in physical rehabilitation of chronic kidney disease; particularly whom undergoing hemodialysis. Multimodal therapeutic approaches may maximize their recovery through preliminary evidence indicating…
- Conditions
- Chronic Kidney Disease (Stages 3b-5), Hemodialysis, Shoulder Adhesive Capsulitis
- Trial name
- NCT07760285
- Testing
- Virtual Reality session, intradialytic neuromuscular electrical stimulation, Maitland Mobilization
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Adly A Adam
Motoric Cognitive Risk Syndrome
Motor-Cognitive Training for Motoric Cognitive Risk Syndrome
The goal of this clinical trial is to investigate if combined motor-cognitive training can improve motor and cognitive symptoms in older adults with motoric cognitive risk syndrome.
- Trial name
- VRTT for MCR (NCT07223905)
- Testing
- Virtual Reality Treadmill Training, Treadmill Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Kansas Medical Center
Forearm Fractures, Procedural Anxiety
Virtual Reality-Assisted Cast Application in Children With Forearm Fractures
This prospective randomized controlled trial will evaluate whether virtual reality can reduce procedural distress in children undergoing cast application for forearm fractures.
- Conditions
- Forearm Fractures, Procedural Anxiety, Doctor-Related Fear
- Trial name
- VR-CAST (NCT07683715)
- Testing
- Virtual Reality-Based Educational Animation, Standard Care
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Spinal Cord Injury, Stroke
Investigating Techniques to Enhance the Sense of Embodiment in Immersive Virtual Reality
Embodiment is an important aspect of virtual reality because it affects how natural and engaging the experience feels and can influence performance and learning in VR-based applications, including rehabilitation [McAnally \&…
- Conditions
- Spinal Cord Injury, Stroke, Healthy
- Trial name
- NCT07870044
- Testing
- Immersive Virtual Reality Embodiment Manipulations
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Surgical, Anxiety
Virtual Reality Therapy to Improve Arthroplasty Outcomes
Virtual reality (VR) has recently emerged as a non-medication-based method to manage anxiety. The patient wears a VR headset and is offered an immersive environment with hypnotic components with sound and imagery in a 3D…
- Conditions
- Surgical, Anxiety, Pain Management, Joint (Knee or Hip Replacement)
- Trial name
- VROOM (NCT07872670)
- Testing
- Virtual Reality Headset, Blood Samples, Questionnaires
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- NHS Highland Research, Development and Innovation Organisation
Procedural Pain Relief, Virtual Reality
AI-Generated Video Distraction Via Virtual Reality for Fear and Pain During Pediatric Circumcision
This randomized controlled trial evaluated the effect of artificial intelligence-generated video distraction delivered via virtual reality on procedural fear and pain in children undergoing circumcision.
- Conditions
- Procedural Pain Relief, Virtual Reality, Fear, Child
- Trial name
- NCT07824427
- Testing
- AI-Generated Video Distraction via Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
End-Stage Kidney Disease (ESKD)
Virtual Reality-Guided Imagery in Hemodialysis Patients ( VRGI-HD )
This randomized controlled trial aims to evaluate the effect of virtual reality guided imagery on selected health outcomes among adult patients receiving maintenance hemodialysis.
- Trial name
- NCT07867444
- Testing
- virtual reality-guided imagery (VRGI)
- Volunteers
- 80 people
- Sponsor
- Islamic University of Najaf
Cerebral Palsy
Telehealth Virtual Reality Gaming on Cardiometabolic Health Among Youth With Cerebral Palsy
The primary purpose of this study is to examine the preliminary efficacy of 12-weeks of home-based exercise using consumer available virtual reality gaming technology, compared with a 12 week wait-list control group.
- Trial name
- NCT05336227
- Testing
- Virtual Reality Exergaming
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Attention Deficit Hyperactivity Disorder
Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Pilot Phase I and Randomized Controlled Phase II Trial
Background: Children with attention deficit hyperactivity disorder (ADHD) often have cognitive problems. It may be hard for them to control their behaviors, concentrate for long periods, or make decisions.
- Trial name
- NCT05608434
- Testing
- Non-adaptive Floreo VR control, Floreo Virtual Reality application
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- National Institute of Mental Health (NIMH)
Adhesive Capsulitis, Virtual Reality
The Effects of Immersive Virtual Reality in Patients With Grade 1-2 Adhesive Capsulitis
Adhesive capsulitis (frozen shoulder) is a complex condition characterized by inflammation, fibrosis, and restriction of movement in the shoulder capsule, significantly limiting an individual's participation in daily living…
- Conditions
- Adhesive Capsulitis, Virtual Reality, Sleep, Pain
- Trial name
- NCT07236229
- Testing
- Conventional Physiotherapy Group, Immersive Virtual Reality-Based Exercise Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Bahçeşehir University