Clinical trials: Lidocaine
Pain
NS1209 and Lidocaine in Patients With Peripheral Neuropathic Pain
Purpose: To evaluate the efficacy, tolerability and safety of NS1209 compared to lidocaine and placebo in patients with peripheral chronic neuropathic pain.
- Trial name
- NCT00258622
- Testing
- NS1209, Lidocaine
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Danish Pain Research Center
Refractory Migraine
Localized Injection of Lidocaine and Glucocorticoid for Headache Treatment Phase 1
The goal of this clinical trial is to test whether injecting lidocaine and steroids into two blood vessels of the brain can help treat chronic headaches (migraines).
- Trial name
- LIGHT 1 (NCT06462781)
- Testing
- Lidocaine hydrochloride, Methylprednisolone sodium succinate
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cooper Norcross Health
Pain Management
Erector Spinae Regional Anesthesia for Pain Control
Interventional study to use erector spinae plane block (ESPB) on diagnoses of posterior or lateral rib fractures, vertebral fractures, pancreatitis, pancreatic cancer, renal colic, and back pain for multimodal pain therapy to…
- Trial name
- NCT05794828
- Testing
- Bupivacaine Injection
- Where
- 4 sites in United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Neuralgia, Peripheral Neuropathic Pain
Randomized Controlled Trial of Efficacy and Safety of Local Anesthetics and Steroids for Chronic Peripheral Post-traumatic Neuropathic Pain
The purpose of this study is to evaluate three different injectable solutions used to block ankle nerves to manage ankle pain. The current standard of medical care is to inject a combination of local anesthetics and steroids…
- Trial name
- RESPERIST (NCT03009500)
- Testing
- Bupivacaine, Depo-Medrol Injectable Product, Saline (Sodium Chloride) solution
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University Health Network, Toronto
Coughing, Extubation
Effect of Intracuff Alkalinized Lidocaine on Coughing Incidence at Extubation
The purpose of the study is to determined whether the administration of alkalized 4% lidocaine (160 mg) in the endotracheal tube cuff is effective in diminishing the incidence of coughing at extubation in surgeries lasting more…
- Conditions
- Coughing, Extubation, Lidocaine, Endotracheal Cuff
- Trial name
- NCT01774292
- Testing
- Endotracheal intubation with injection of liquid in the cuff
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Université de Sherbrooke
Vaginal Atrophy
Comparative Study: Vaginal Promestriene Use, Fractional CO2 LASER and Radiofrequency in the Vaginal Atrophy Treatment
Postmenopausal hypoestrogenism may determine genital atrophy, which may be accompanied by a non-specific inflammatory process and may hinder or even prevent sexual intercourse.
- Trial name
- NCT04717245
- Testing
- Promestriene Vaginal, Fractional CO2 LASER, Microablative Fractional radiofrequency
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- University of Sao Paulo General Hospital
Pain, Analgesia
The Use of Micro Vibratory Stimulation Technique to Control the Pain of Digit Block Anesthesia
The investigators hypothesize that patients who receive 1% lidocaine injections for digit blocks of the finger will experience less pain when the injection is accompanied by the use of a micro-vibratory stimulator (MVS) compared…
- Trial name
- NCT02870595
- Testing
- Microvibratory Stimulator, Microvibratory Stimulator'
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Christus Spohn Memorial Medical Center
Liver Cancer, Post Ablation Syndrome
The Role of 5% Lidocaine Patches in the Pain Control of Hepatocellular Carcinoma Patients Receiving Radiofrequency Ablation
Background: This study aims to test whether 5% lidocaine patches can reduce Radiofrequency ablation-induced pain. Methods: The study will enroll patients with hepatocellular carcinoma and schedule a radiofrequency ablation…
- Trial name
- NCT05732181
- Testing
- The skin lidocaine patch.
- Where
- Taiwan
- Volunteers
- 154 people
- Sponsor
- National Cheng-Kung University Hospital
The Effect of Ketamine - Dexmedetomidine Admixture (Ketodex) on Hemodynamic Stability
The Effect of Ketamine - Dexmedetomidine Admixture (Ketodex) on Hemodynamic Stability During Anesthesia Induction in Adults.
The aim of our study to compare two different doses of Dexmedetomidine added to anesthetic dose of ketamine in the induction of general anesthesia in adult patients regarding the hemodynamic profile, adequacy of hypnosis…
- Trial name
- NCT05948267
- Testing
- ketamine- dexmeditomidine admixure, Propofol, Lidocaine and fentanyl
- Where
- 2 sites in Egypt
- Volunteers
- 120 people
- Sponsor
- Kasr El Aini Hospital
Back Pain, Neck Pain
Treatment of Chronic Thoracic and Neck and Upper Extremity Pain
To study improvements or lack thereof with the interlaminar epidural patients with or without steroids experiences mid back, upper back or neck pain with or without chest wall and upper extremity pain of at least 6-months…
- Trial name
- NCT01071369
- Testing
- Xylocaine, Xylocaine and Celestone
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Pain Management Center of Paducah
Labor Pain
Effect of Epidural Analgesia on the Parameter ANI During Childbirth
There are many methods used for the assessment of pain in the area of anesthesia including heart rate variability which reflects the influence of the autonomic nervous system on the heart.
- Trial name
- APD-ANI (NCT01505283)
- Testing
- NaCl 0.9%, Sufentanil, lidocaine
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Hopital Foch
Chronic Pain
Steroid Versus Platelet Rich Plasma Injection for Chronic Low Back Pain
Chronic low back pain, with or without lower extremity pain, which arises from various structures of the spine constitutes a majority of pain complaints.
- Trial name
- NCT02334475
- Testing
- Platelet Rich Plasma, methylprednisolone
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Labor Pain
Comparison of Dural Puncture Epidural Versus Conventional Epidural for Labour Analgesia in Primigravida
This study aims to compare the analgesic efficacy and safety of the Dural Puncture Epidural (DPE) technique versus the Conventional Epidural (CE) technique for labor analgesia in primigravida.
- Trial name
- NCT06766812
- Testing
- epidural set
- Volunteers
- 60 people
- Sponsor
- Sohag University
Headaches Associated With Subarachnoid Hemorrhage (SAH)
IA Lidocaine and Methylprednisolone for Headache Associated With Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) is a type of bleeding around the brain that can cause sudden and severe headaches. These headaches can be debilitating and persist for weeks, significantly impacting a patient's comfort and recovery.
- Trial name
- LIMSAH (NCT07054801)
- Testing
- Lidocaine hydrochloride, Methylprednisolone sodium succinate
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Daniel Raper, MBBS
Trigger Finger, Stenosing Tenosynovitis
Resection of Flexor Digitorum Superficialis Tendon for Severe Trigger Fingers
The purpose of this study is to compare the effectiveness of resection of one or both slips of the flexor digitorum superficialis tendon versus the A1 pulley division.
- Trial name
- NCT04675892
- Testing
- A1 pulley division, A1 pulley division + Resection of one or both slips of the FDS tendon
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Vulvodynia
A Trial of Intravesical Therapy for Interstitial Cystitis in Patients With Generalized Vulvodynia
In order to investigate whether the pain in women with vulvodynia may represent bladder origin pain, we will be performing a diagnostic test for interstitial cystitis (IC) in women with generalized vulvodynia.
- Trial name
- VV/IC (NCT01048177)
- Testing
- Bladder instillation with heparin/ lidocaine
- Where
- United States
- Sponsor
- Scripps Health
Intubation; Difficult or Failed, Obesity
The Role of Anthropometric Measurements and Ultrasonograpic Suprasternal Adipose Tissue Thickness
Prediction of difficult preoperative intubation in obese patients and completion of preparations for difficult intubation both reduce the risk of repeated intubation and prevent complications.
- Conditions
- Intubation; Difficult or Failed, Obesity, Anesthesia
- Trial name
- NCT06457165
- Testing
- Difficult Intubation, Not Difficult Intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara City Hospital Bilkent
Skin Regeneration
The Effect of Stromal Vascular Fraction Transplantation on the Regeneration of Expanded Skin
This study is a randomized controlled trial aimed at evaluating the effect of intradermal stromal vascular fraction (SVF) transplantation in treating exhaustion of dermal regenerative capacity during skin expansion.
- Trial name
- NCT07114692
- Testing
- Stromal vascular fraction transplantation, Normal saline injection
- Volunteers
- 20 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Myofascial Pain
Multi-modal Imaging of Myofascial Pain - Phase 2
The goal of this study is to evaluate imaging biomarkers for quantitative assessments of myofascial pain and determine their ability to monitor treatment response and predict clinical outcomes.
- Trial name
- NCT07322445
- Testing
- 50/50 Mixture of Lidocaine 1% injection + Bupivacaine 0.25% Injectable Solution, Dry Needling
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Washington University School of Medicine
Cholelithiasis
Comparing Epidural Versus General Anesthesia for LESS Cholecystectomies
This study is a prospective, comparative, controlled, blinded study that will enroll a total of 70 adults that will undergo elective laparoendoscopic single-site incision gallbladder removal.
- Trial name
- NCT03247257
- Testing
- General Anesthesia, Epidural Anesthesia
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Florida Hospital Tampa Bay Division
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