Clinical trials: Lidocaine
Subarachnoid Hemorrhage in Adult Patients
Sphenopalatine Block in Headache in Patients With Non-traumatic Subarachnoid Hemorrhage
Non-traumatic SAH, linked in 85% of cases to the rupture of an intracranial aneurysm, is a serious stroke affecting young people. Half of all survivors suffer cognitive impairment.
- Trial name
- SATURN (NCT06735261)
- Testing
- Sphenopalatine Ganglion Block using 2% lidocaine
- Volunteers
- 70 people
- Sponsor
- University Hospital, Grenoble
Intubation Complication, Cardiovascular Morbidity
The Effects of Lidocaine and Magnesium Sulphate on the Attenuation of the Hemodynamic Response to Tracheal Intubation
Justification and Objectives: The hemodynamic response to stimuli of the airways is a common phenomenon and its control is important to decrease systemic repercussions.
- Trial name
- NCT02359370
- Testing
- Lidocaine, Magnesium Sulphate
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Hospital de Base
Early Confirmation of Epidural Catheterization
Early Detection of Epidural Onset by Temperature Change
Traditionally, placement of the epidural catheter is based on hand feel of passing through the ligamentum flavum as well as "loss of resistance" while injecting the air through the needle.
- Trial name
- NCT02838056
- Testing
- epidural injection
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Medical University WanFang Hospital
Abortion, Spontaneous, Abortion in First Trimester
Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage.o
The investigators are conducting a study on pain control for dilation and curettage (D\&C). Participants are eligible to enroll if they are a planning to have a D\&C in a participating clinic.
- Conditions
- Abortion, Spontaneous, Abortion in First Trimester, Pain Uterus, Abortion Early
- Trial name
- NCT03636451
- Testing
- 40cc buffered 0.5% lidocaine with 2 units of vasopressin paracervical block, 20cc 1% lidocaine with 2 units of vasopressin paracervical block
- Where
- 2 sites in United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Alveolar Cleft
Assessment of Nanocrystalline Hydroxyapatite Versus Autogenous Bone Grafts : A Comparative Clinical Study in Alveolar Cleft Grafting
This work aims to evaluate Nanocrystalline Hydroxyapatite versus Autogenous bone grafts in alveolar cleft grafting
- Trial name
- NCT04693559
- Testing
- secondary alveolar bone graft, harvesting of the autogenous bone graft, Nanocrystalline Hydroxyapatite
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Recurrent Low Back Pain, Degenerative Disc Disease (DDD)
Efficacy of Intradiscal Injection of BM-MSC in Subjects With Chronic Low Back Pain (LBP) Due to Lumbar Degenerative Disc Disease (DDD) Unresponsive
This will be a multicenter, prospective, double blind, randomized phase 2/3 trial comparing culture-expanded allogeneic adult BM-MSCs with sham-treated controls.
- Trial name
- RESPINE (NCT03737461)
- Testing
- Allogenic BM-MSCs Injection
- Where
- 9 sites in France, Germany and 2 more
- Volunteers
- 113 people
- Sponsor
- University Hospital, Montpellier
Lung Neoplasms
A Comparison Between EBUS-GS and CT-guided Lung Biopsy in Diagnosis of Peripheral Pulmonary Lesions.
This is a randomized controlled trail aiming at comparing the diagnostic value and safety of endobronchial ultrasonography with a guide sheath(EBUS-GS) and computed tomography-guided transthoracic needle biopsy(CT-TTNB) for…
- Trial name
- NCT02740400
- Testing
- EBUS-GS, CT-TTNB
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University People's Hospital
Sore Throat
Inhalation of Lidocaine Before Intubation
We investigate the potential benefits of ultrasound-driven lidocaine inhalation immediately before induction.
- Trial name
- NCT01838993
- Testing
- Lidocaine inhalation
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- New Taipei City Hospital
Pelvic Organ Prolapse, Stress Urinary Incontinence
Lidocaine for Pessary Check Pain Reduction
The primary objective of this study is to estimate the effect of lidocaine jelly on patient pain at the time of office pessary removal.
- Trial name
- NCT05493735
- Testing
- Lidocaine Hcl 2% Jelly
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Malocclusion
Micro-osteoperforations and Tooth Movement
The purpose of this study is determine the effect the Microosteoperforation (MOPs) using the miniscrew on the rate tooth movement.
- Trial name
- NCT02473471
- Testing
- Micro-osteoperforation
- Where
- Jordan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Hip Pain Chronic, Osteoarthritis, Hip
Pericapsular Nerve Group Block Added to Intra-articular Corticosteroid Injection in the Treatment of Hip Pain
Osteoarthritis (OA) is a leading cause of chronic musculoskeletal pain and functional disability worldwide, affecting an increasing number of people.
- Trial name
- PENGandIAI (NCT07427238)
- Testing
- Intra-articular injection, Intra-articular injection + PENG blok
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Saglik Bilimleri Universitesi
Epidural Analgesia, Postoperative Pain
Comparison of the Incidence of Inadequate Epidural Analgesia Between Protocol Based and Current Practice
Epidural analgesia is the recommended analgesic technique in patients having surgery with severe postoperative pain such as thoracic and upper abdominal surgery.
- Trial name
- NCT04111406
- Testing
- Current practice, Protocol based
- Where
- Thailand
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Post-mastectomy Pain Syndrome, Breast Cancer
Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)
Phase III, international multicentre, parallel group, blinded, 1:1 randomized controlled trial to determine the effect of an intraoperative intravenous lidocaine infusion on reducing the development of persistent pain 3-months…
- Conditions
- Post-mastectomy Pain Syndrome, Breast Cancer, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT04874038
- Testing
- Lidocaine 20mg/ml
- Where
- 17 sites in Canada, Nepal and 1 more
- Volunteers
- 1,604 people
- Sponsor
- University Health Network, Toronto
Wounds, Local Anesthesia
To Evaluate Reduction of Pain in Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo
The purpose of this study is to evaluate if applying a lidocaine topical solution before wounds treatment decreases the pain of the procedure in comparison with placebo solution.
- Trial name
- NCT02584335
- Testing
- Lidocaine solution ("A"), Saline solution ("B")
- Where
- Spain
- Volunteers
- 7 people
- Sponsor
- Hospital Universitari de Bellvitge
Hip Disease
Evaluation of Anterior Quadratus Lumborum Block for Postoperative Analgesia in Hip Arthroscopy
Hip arthroscopy is performed frequently and the postoperative course often involves moderate to severe pain. There remains no definitive perioperative pain regimen that has been proven to be effective and safe for this ambulatory…
- Trial name
- NCT03432650
- Testing
- Bupivacaine + dexamethasone, Ultrasound
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Hospital for Special Surgery, New York
Aesthetics
Long Term Safety and Efficacy Assessment of Hyaluronic Acid Dermal Filler With for the Treatment of Nasolabial Folds
This study evaluates the injection of a hyaluronic acid dermal filler with lidocaine 0.3% in the treatment of nasolabial folds (NLF).
- Trial name
- ECLAH (NCT02703740)
- Testing
- Hyaluronic acid dermal filler with lidocaine 0.3%
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laboratoires Genévrier
Pancreatoduodenectomy, Pain Management
Continous Infusion of Nefopam for Patients Undergoing Pancreatoduodenectomy
The goal of this clinical trial is to determine whether continuous nefopam administration, as part of a multimodal analgesia strategy, reduces opioid consumption and improves patient satisfaction after pancreatoduodenectomy.
- Conditions
- Pancreatoduodenectomy, Pain Management, Opioid Analgesia, Multimodal Analgesia
- Trial name
- NCT07423650
- Testing
- Nefopam 120mg/day infusion, Lidocaine Infusion, Peridural
- Where
- Romania
- Volunteers
- 93 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Cholesteatoma, Chronic Otitis Media
Combined Access Closed Tympanomastoidectomy: Microsurgery Allied to Endoscopy
Chronic otitis media is a prevalent medical condition, leading to important impact in the lives of the individuals with this condition, and a great amount of patients may need surgical intervention.
- Trial name
- NCT03294421
- Testing
- combined access tympanomastoidectomy, standard closed tympanomastoidectomy
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Dental Pain
Buffered Local Anesthetic
The purpose of this research study is to compare responses in children during dental injections of local anesthetic (used for numbing), while children are under deep sedation (breathing on their own, often with a loss of…
- Trial name
- NCT05757648
- Testing
- Non-buffered Anesthetic, Buffered Anesthetic, Onset
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Diabetic Foot Ulcers
Omeza Products in Combination With Standard of Care for the Treatment of Diabetic Foot Ulcers
This study is to evaluate the efficacy of OCM™ used in combination with off-loading devices for the treatment of diabetic foot ulcers.
- Trial name
- NCT05417425
- Testing
- Omeza collagen matrix, Omeza lidocaine lavage, Omeza skin protectant
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Omeza, LLC
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