Clinical trials: Lidocaine
Pharyngitis
Clinical Trial for Assessment of Safety and Efficacy of a Echinacea/Sage Spray Compared to a Chlorhexidine/Lidocaine Spray in the Treatment of Acute Sore Throats
The aim of the study is to show non-inferiority of an echinacea/sage spray compared to a chlorhexidine/lidocaine-spray in the treatment of acute sore throat during five days of treatment.
- Trial name
- NCT00707902
- Testing
- chlorhexidine/lidocaine, echinacea/sage
- Where
- Switzerland
- Volunteers
- 154 people
- Sponsor
- A. Vogel AG
Dyspepsia, Malabsorption Syndrome
Evaluation of Topical Lidocaine Spray as Adjuvant to Upper Gastrointestinal Endoscopy in Children
There is some controversy in the medical literature regarding the effectiveness of topical lidocaine in children as an adjuvant drug to upper gastrointestinal endoscopy.
- Conditions
- Dyspepsia, Malabsorption Syndrome, Gastroesophageal Reflux Disease, Abdominal Pain
- Trial name
- NCT00521703
- Testing
- Lidocaine, Tannic acid
- Where
- Brazil
- Volunteers
- 78 people
- Sponsor
- Hospital Infantil Cândido Fontoura
Laminectomy
Preemptive Analgesia for Postlaminectomy
To relieve post laminectomy pain, we have tried intraoperative perineural injection of lidocaine right after the exposure in expecting that this would be preemptive analgesia by blocking the nerve transmission so that…
- Trial name
- NCT00656526
- Testing
- Lidocaine, perineural injection, intraoperatively, Lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Harran University
Migraine Headache
A Double Blind Randomized Controlled of Placebo and Nebulized Lidocaine for Migraine Headache
Migraine headaches have previously been shown to be responsive to intranasal lidocaine in a small study. Using a nebulizer to administer the drug would improve the feasibility of using the treatment.
- Trial name
- NCT00287781
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Kern Medical Center
Postoperative Ileus
Effects of Intravenous Local Anesthetic on Bowel Function After Colectomy
Epidural local anesthetics are the gold standard for shortening duration of bowel dysfunction after bowel surgery. Previous studies suggest that their effect may be in part a result of actions of the local anesthetic outside the…
- Trial name
- NCT00600158
- Testing
- bupivacaine with hydromorphone, lidocaine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Virginia
Fevers, Pain
Lidocaine Lubricant in Pediatric Urethral Catheterization
In Emergency Departments (ED) across the nation there is renewed interest in finding ways to alleviate the pain and discomfort associated with many of the procedures that children must undergo.
- Trial name
- NCT00596375
- Testing
- Lubricant Instillation, Lidocaine Lubricant
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Children's Healthcare of Atlanta
Healthy
Safety and Efficacy of Lidocaine Infiltration in Suction Assisted Lipectomy
RCT of S/E of lidocaine infiltration in tumescent technique.
- Trial name
- NCT00591487
- Testing
- Lidocaine
- Where
- Chile
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Militar de Santiago
Pain
NS1209 and Lidocaine in Patients With Peripheral Neuropathic Pain
Purpose: To evaluate the efficacy, tolerability and safety of NS1209 compared to lidocaine and placebo in patients with peripheral chronic neuropathic pain.
- Trial name
- NCT00258622
- Testing
- NS1209, Lidocaine
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Danish Pain Research Center
Vulvar Disease
Vulvar Vestibulitis Clinical Trial: Desipramine-Lidocaine
The Vulvar Vestibulitis Clinical Trial (VVCT) a randomized, placebo-controlled, double blinded clinical trial. We will study the clinical efficacy of four medical treatments for vulvar vestibulitis: topical lidocaine, oral…
- Trial name
- NCT00276068
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Planned Abdominal Hysterectomy
Optimal Multimodal Analgesia in Abdominal Hysterectomy
The purpose of this study is to test the current standard of care (SOC) treatment for abdominal hysterectomy with a group receiving SOC minus epidural analgesia plus additional perioperative analgesics in terms of postoperative…
- Trial name
- NCT00209872
- Testing
- Gabapentin, Lidocaine, S-ketamine
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Hvidovre University Hospital
Infertility
Local Anaesthetic for Transvaginal Egg Collection in IVF
The purpose of this study is to see whether injecting local anaesthetic into the vaginal tissues,just prior to transvaginal egg collection,will decrease the amount of pain experienced by women having their eggs collected on an…
- Trial name
- NCT00554424
- Testing
- lignocaine, normal saline
- Where
- New Zealand
- Volunteers
- 75 people
- Sponsor
- The Fertility Centre, New Zealand
Cancer, Pain
Benefit of Lidocaine Perfusion in Cancer Related Visceral Pain Resistant to Morphinics
This study will evaluate the benefit of lidocaine perfusion in cancer related visceral pain resistant to morphinics. It is an efficacy study in adults and children and a randomized prospective study.
- Trial name
- NCT00181012
- Testing
- Lidocaine
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Induction of Total Intravenous General Anesthesia
Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion
Propofol is a popular intravenous drug to induce anesthesia but it causes local pain with an incidence between 40 and 90%. Three different strategies to prevent propofol induced pain will be studied compared with placebo.
- Trial name
- NCT00146926
- Testing
- kétamine 20mg, ephedrine 3mg, lidocaine 40mg
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Colorectal Cancer
Intra-op Lidocaine and Ketamine Effect on Postoperative Bowel Function
Bowel function after bowel surgery is delayed (postoperative ileus)by both opiates and the surgery itself. We hypothesized that decreasing opiate use by other analgesics will speed the return of bowel function after surgery.
- Trial name
- NCT00229567
- Testing
- Lidocaine infusion plus ketamine injection
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Saskatchewan
Pain
Jet Injection of 1% Buffered Lidocaine Versus Topical ELA-Max for Anesthesia Prior to Intravenous (IV) Catheterization in Children
This trial is a comparison of the anesthetic effectiveness of J-Tip needle-free jet injection of 1% buffered lidocaine to the anesthetic effectiveness of topical 4% ELA-Max for peripheral intravenous catheter (PIV) insertion.
- Trial name
- NCT00444756
- Testing
- J-tip jet injection of 1% buffered lidocaine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Norton Healthcare
Lung Cancer
Anesthesia in Flexible Bronchoscopy for Lung Cancer Diagnostic
The objective of the study was to establish which anesthetic procedure used during flexible bronchoscopy has the lowest index of complications.
- Trial name
- NCT00440960
- Testing
- propofol, midazolam, alfentanil
- Where
- 3 sites in Brazil
- Sponsor
- Hospital Pompeia
Pelvic Pain, Interstitial Cystitis
Study of U101 for Bladder Pain and/or Urgency
The purpose of this study is to determine whether intravesical U101 (alkalinized lidocaine-heparin) treatment reduces the symptoms of pelvic pain and/or urgency of bladder origin.
- Conditions
- Pelvic Pain, Interstitial Cystitis, Bladder Diseases
- Trial name
- NCT00256542
- Testing
- Alkalinized Lidocaine-Heparin
- Where
- 9 sites in United States
- Volunteers
- 90 people
- Sponsor
- Urigen
Breast Pain
Premedication to Reduce Discomfort With Screening Mammography
This study will explore the effect of pre-medication with acetaminophen, ibuprofen, and topical lidocaine gel (Topicaine) on the perception of discomfort and overall satisfaction with the mammography experience.
- Trial name
- NCT00382083
- Testing
- 1000 mg acetaminophen, 800 mg ibuprofen, 1 oz 4% lidocaine gel
- Where
- United States
- Sponsor
- Mountain States Tumor and Medical Research Institute
Pain, Hyperalgesia
Effects of Lidocaine Patch on Intradermal Capsaicin Induced Pain and Hyperalgesia
To determine the effects of Lidocaine patch on the pain and hyperalgesia induced by intradermal capsaicin
- Trial name
- NCT00373893
- Testing
- Lidoderm Patch
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Infertility
Intracervical Block Versus Placebo to Assess Pain Control During Hysterosalpingogram
The purpose of this study is to compare the efficacy of 1% lidocaine intracervical block to placebo for pain control during the performance of a hysterosalpingogram (HSG).
- Trial name
- NCT00372658
- Testing
- 1% Lidocaine intracervical injection
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing