Clinical trials: Fentanyl, completed
Postoperative Pain After Thoracic Surgery, Postoperative Pain
Comparison of IV Analgesia Protocols After the Regional Block's Effect Diminishes in Thoracic Surgery
The purpose of this study is to compare the effectiveness of three different intravenous (IV) patient-controlled analgesia (PCA) regimens-Fentanyl, Tramadol, and Ibuprofen-in managing postoperative pain and respiratory…
- Conditions
- Postoperative Pain After Thoracic Surgery, Postoperative Pain, Thoracic Surgery, Video Assisted, Patient Controlled Analgesia
- Trial name
- NCT07610408
- Testing
- Fentanyl IV PCA, Tramadol IV PCA, Ibuprofen IV PCA
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Ankara Etlik City Hospital
Minimal Flow Anesthesia, General Anaesthesia
Minimal Flow Anesthesia and Infection Risk
This study is being done to find out if the heat and moisture that build up during minimal flow anesthesia can lead to the growth of germs (microorganisms) inside the anesthesia equipment.
- Conditions
- Minimal Flow Anesthesia, General Anaesthesia, Inhalation Anesthesia, Infection Risk
- Trial name
- NCT07092046
- Testing
- Sevoflurane (Volatile Anesthetic), Propofol 1%, Remifentanil 2 MG
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Knee Replacement, Total
Implementation of a Pain Management Protocol for Total Knee Arthroplasty
Study question: Is there an ideal combination of intraoperative long acting analgesics (periarticular infiltration (PI), femoral nerve block (FB) and intrathecal opioids (IO)) to optimize post-operative functional recovery…
- Trial name
- NCT02474654
- Testing
- Bupivicaine, Fentanyl, Epimorphine
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- Health Sciences North Research Institute
Treatment Side Effects, Musculoskeletal Pain
A Randomized Study Comparing of Three Doses Nebulized Fentanyl in Older Adults
This clinical trial compares three different nebulized fentanyl dosages for older persons experiencing severe musculoskeletal pain at the emergency department.
- Trial name
- NCT06689124
- Testing
- Nebulized fentanyl
- Where
- 2 sites in Thailand
- Volunteers
- 120 people
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Lumbar Spine Fixation
Fentanyl as Adjuvants to Epidural Bupivacaine Plus Dexamethasone for Analgesia
The purpose of this study is to compare better postoperative analgesia after lumbar spine Fixation using either epidural bupivacaine with midazolam or fentanyl with the combination of dexamethasone.
- Trial name
- NCT06898697
- Testing
- postoperative analgesia, epidural fentanyl
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
Electroencephalography, Craniotomy Surgery
Evaluation of Response to Pain From Skull Pin Fixation in Craniotomies
The goal of this observational study is to investigate the relationship between the response to skull pin fixation pain and the analysis of blood pressure, heart rate, and brain wave activity in adults undergoing brain surgery.
- Conditions
- Electroencephalography, Craniotomy Surgery, Pain Management
- Trial name
- NCT06811701
- Testing
- Scalp nerve block, Opioid Anesthetics, Local Anesthetic Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Diskapi Teaching and Research Hospital
Opioid Use, Affective Symptoms
Affective Effects of Pre-surgery Opioids: a Randomized, Doubleblind Placebo-controlled Trial
1. To investigate and compare the affective short-term effects of opioid drugs: morphine, oxycodone and fentanyl, administered to the patients before the induction of general anesthesia. 2.
- Trial name
- AFFECT2 (NCT05639712)
- Testing
- Morphine 2.5 mg i.v., Morphine 5 mg i.v., Morphine 10 mg i.v.
- Where
- Norway
- Volunteers
- 1,014 people
- Sponsor
- Oslo University Hospital
Heart Defects, Congenital, Myocardial Reperfusion Injury
Morphine Versus Fentanyl for Myocardial Protection in Acyanotic Children Undergoing Congenital Open-Heart Surgery
This study compared two opioid pain medications - morphine and fentanyl - used during open-heart surgery in young children born with heart defects (congenital heart disease).
- Trial name
- MorphPed (NCT07839273)
- Testing
- Fentanyl (IV), morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Baskent University
Fentanyl, Dexmedetomidine
Fentanyl Vs Dexmedetomidine as Adjuvants to Bupivacaine in Erector Spinae Plane Block for Postoperative Analgesia in Patients Undergoing Arthroscopic Shoulder Surgeries
This study aimed to evaluate the effect of fentanyl versus dexmedetomidine as adjuvants to bupivacaine with comparison to bupivacaine alone in ultrasound-guided erector spinae plane block on the quality and duration of pain…
- Conditions
- Fentanyl, Dexmedetomidine, Bupivacaine, Erector Spinae Plane Block
- Trial name
- NCT07836595
- Testing
- Bupivacaine 0.25%, Bupivacaine 0.25% + Fentanyl 1µg/kg, Bupivacaine 0.25% + dexmedetomidine 1µg/kg
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Post Operative Pain, Preemptive Analgesia
Paracetamol Plus Tramadol Versus Fentanyl in Day Case Surgeries
Postoperative pain is an important problem, especially for day case surgeries. It has negative effects on patient's hemodynamics and can cause delayed ambulation resulting in prolonged duration of hospital stay and poor patient…
- Trial name
- NCT05990686
- Testing
- tramadol plus paracetamol, Fentanyl Injection
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Pain, Postoperative / Acute Pain
Opiranserin Injections PCA Regimens for Postoperative Pain
The purpose of this phase 2 study is to evaluate the efficacy and safety of PCA regimen of opiranserin (VVZ-149) injections in patients undergoing laparoscopic colectomy.
- Trial name
- NCT07821307
- Testing
- VVZ-149 Injections, Fentanyl
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Samsung Medical Center
Breast Cancer
Ultrasound Guided Serratus Anterior Plane Block Versus Ultrasound Guided Thoracic Epidural Analgesia
Regional/local analgesic techniques are an important component of a multimodal analgesic strategy, with the aim of reducing opioid requirements and opioid-related adverse events.
- Trial name
- NCT07807605
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Beni-Suef University
Hydromorphone, Analgesia
Hydromorphone for ICU-analgesia in Patients With Non-mechanical Ventilation
Hydromorphone has a clear analgesic effect, and has few advantages in respiratory depression and gastrointestinal motility. The study will further explore the continuous pumping-dose of hydromorphone for ICU non-mechanical…
- Conditions
- Hydromorphone, Analgesia, ICU
- Trial name
- NCT04436224
- Testing
- Hydromorphone, Fentanyl, Butorphanol
- Where
- China
- Volunteers
- 530 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Breast Cancer
Opioid-Free Versus Opioid-Based Anesthesia in Modified Radical Mastectomy
This randomized controlled trial compares opioid-free anesthesia combined with pectoral nerve block (PECS I and II) with opioid-based anesthesia in patients undergoing modified radical mastectomy.
- Trial name
- NCT07798895
- Testing
- Pectoral Nerve Block (PECS I and II), Dexmedetomidine, Fentanyl
- Where
- Indonesia
- Volunteers
- 28 people
- Sponsor
- Muhammad Fiqhi Amiruddin
Postoperative Pain Intensity
Effect of Opioid-Free Versus Opioid-Based Anesthesia in Discectomy Surgery
This prospective randomized double-blind clinical trial compares opioid-free anesthesia (OFA) versus opioid-based anesthesia (OBA) on postoperative analgesia in patients undergoing elective lumbar discectomy surgeries at Zagazig…
- Trial name
- NCT07787858
- Testing
- Dexmedetomidine and Ketamine-based Opioid-free Anesthesia, Fentanyl-based Opioid Anesthesia
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Zagazig University
Delirium - Postoperative
Effect of Dexmedetomidine Dosage on Postoperative Delirium in Geriatric Orthopedic Surgery
This study evaluates the dose-response relationship of Dexmedetomidine (DEX) in reducing the incidence and severity of postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) in elderly patients.
- Trial name
- NCT07443085
- Testing
- Dexmedetomidine (Low dose), Dexmedetomidine (High dose), Fentanyl
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Benha University
Postoperative Pain
Comparison of Pain Relief Duration With Dexmedetomidine Versus Fentanyl Added to Spinal Anesthesia in Patients Undergoing Lower Limb Orthopedic Surgery
The goal of this randomized clinical trial is to compare how long effective pain relief lasts when dexmedetomidine or fentanyl is added to hyperbaric bupivacaine during spinal anesthesia for lower limb orthopedic surgery.
- Trial name
- NCT07770542
- Testing
- Dexmedetomidine & Bupivacaine., fentanyl and bupivacaine
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Allama Iqbal Teaching Hospital
Liver Transplantation
Reducing Pain With Methadone and Ketamine in Liver Transplant
The goal of this clinical trial is to learn if using methadone and ketamine during an adult deceased donor liver transplant can help decrease pain after surgery.
- Trial name
- RELIEF-LT (NCT06868589)
- Testing
- Methadone, ketamine, Hydromorphone
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Lahey Clinic
Coronary Artery Disease (CAD), Left Ventricular (LV) Systolic Dysfunction
Ketamine-lidocaine Versus Ketamine-fentanyl for Induction of Anesthesia in Patients With Left Ventricular Systolic Dysfunction Undergoing Elective Coronary Artery Bypass
This study compares ketamine/fentanyl versus ketamine/lidocaine in term of their impact on cerebral perfusion during CABG. No prior data address these effects, and the goal is to identify the induction regimen that better…
- Conditions
- Coronary Artery Disease (CAD), Left Ventricular (LV) Systolic Dysfunction, Induction Anesthesia, Coronary Bypass Graft Surgery
- Trial name
- NCT07248202
- Testing
- Fentanyl (IV), lidocaine
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Modified Thoracoabdominal Nerve Block (M-TAPA), Analgesic Technique
Bilateral Modified Thoracoabdominal Nerve Block as an Analgesic Technique in Comparison With Bilateral Thoracic Erector Spinae Plane Block in Abdominoplasty Operations
This study aimed to compare the analgesic effect of bilateral ultrasound-guided modified thoracoabdominal nerve block with bilateral ultrasound-guided erector spinae plane block in abdominoplasty surgery.
- Conditions
- Modified Thoracoabdominal Nerve Block (M-TAPA), Analgesic Technique, Thoracic Erector Spinae Plane Block, Abdominoplasty
- Trial name
- NCT07738900
- Testing
- General Anaesthesia using intravenous propofol, fentanyl intravenous, and atracurium besylate, Modified thoracoabdominal nerve block using 25 mL of bupivacaine 0.25%, Erector spinae plane block using 25 mL of bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Mansoura University