Clinical trials: Duloxetine
Major Depressive Disorder
Efficacy and Safety of Duloxetine Among Individuals With Depressive Disorder in a 12 Weeks Trial
The aim of this study was to investigate the effects of duloxetine on improvement of brain cortical activity in patients suffering from major depressive disorder using near infrared spectroscopy.
- Trial name
- NCT03121573
- Testing
- Duloxetine
- Volunteers
- 30 people
- Sponsor
- Taichung Veterans General Hospital
Urinary Stress Incontinence
Biomechanical and Electrophysiological Effects of Duloxetine in the Treatment of Women With Urinary Stress Incontinence
Biomechanical and electrophysiological effects of duloxetine in the treatment of women with urinary stress incontinence
- Trial name
- NCT00190853
- Testing
- Duloxetine
- Where
- 19 sites in United States, Slovenia and 1 more
- Volunteers
- 93 people
- Sponsor
- Eli Lilly and Company
Major Depressive Disorder, Healthy Participants
A Study of the Neurobiology of Depression
Previous research studies have shown that depression is associated with changes in structure and activity in different parts of the brain and that antidepressant medication can affect brain activity in different parts of the…
- Trial name
- NCT01051466
- Testing
- Duloxetine
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Duloxetine, Magnesium Sulphate
Pain Relieving Potentials of Combination of Oral Duloxetine and Intravenous Magnesium Sulphate in Post Mastectomy Pain
This study aims to evaluate the effect of combined duloxetine and IV Magnesium sulphate to decrease acute and chronic post mastectomy pain.
- Conditions
- Duloxetine, Magnesium Sulphate, Post-mastectomy Pain Syndrome
- Trial name
- NCT06087211
- Testing
- Magnesium sulphate and Duloxetine, Duloxetine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Colorectal Cancer
Efficacy of Perioperative Duloxetine as a Part of Multimodal Analgesia in Laparoscopic Colorectal Cancer Surgery
Our aim will be to evaluate the efficacy of perioperative Duloxetine in decreasing acute postoperative pain after laparoscopic colorectal cancer surgery and its role in reducing postoperative morphine requirements
- Trial name
- NCT04294953
- Testing
- Duloxetine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Musculoskeletal Pain
Altering The Transition From Acute to Chronic Pain (ATTAC-Pain)
The current way that pain is treated after trauma and injury is problematic. Most often pain after trauma is treated with opioids (ex. Percocet® or Vicodin®) or anti-inflammatories (ex. ibuprofen).
- Trial name
- ATTAC-PAIN (NCT03315533)
- Testing
- Duloxetine 30 milligrams (MG), Duloxetine 60 milligrams (MG)
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Rhode Island Hospital
Depression, Pain
Subject Information and Consent Form F1J-US-HMCB Duloxetine Once-Daily Dosing Versus Placebo in Patients With Major Depression and Pain
The purposes of this study are to determine whether an investigational drug can help patients suffering from major depression with pain symptoms, and gather data on the safety of the investigational drug including any side…
- Trial name
- NCT00036335
- Testing
- Duloxetine Hydrochloride
- Where
- 25 sites in United States
- Volunteers
- 286 people
- Sponsor
- Eli Lilly and Company
Bioequivalence
Bioavailability of Duloxetine 60 mg With Regards to Reference Product in Feeding Conditions
This Study will investigate the bioavailability in fasting subjects of 1 capsule formulation containing Duloxetine 60 mg. The Study will be performed at a single site with 36 subjects.Participants will take 1 capsule of the test…
- Trial name
- NCT04751318
- Testing
- Duloxetine 60mg Test Drug Enteric Coated Granules, Duloxetine 60mg Reference Product Enteric Coated Granules
- Where
- Chile
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Laboratorios Andromaco S.A.
Binge Eating, Depression
Study of Duloxetine vs Placebo in Treatment of Binge Eating Disorder With Depression
The purpose of this research study is to test the safety of duloxetine and see what effects (good and bad) it has on the subject's binge eating disorder and comorbid depressive disorder (depression occurring with binge eating…
- Trial name
- NCT00607789
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Cincinnati
Chronic Kidney Disease
Serotonin Norepinephrine Reuptake Inhibitors and the Risk of Serious Adverse Events
This is a population-based retrospective, new-user design, active comparator cohort study assessing whether initiating a new outpatient prescription of high-dose serotonin norepinephrine reuptake inhibitors (SNRIs)-venlafaxine…
- Trial name
- NCT07531173
- Testing
- Venlafaxine or duloxetine
- Volunteers
- 8,688 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Anxiety
Duloxetine vs Placebo in the Treatment of General Anxiety
To see if duloxetine 60 to 120 mg once daily (QD) is better than placebo in the treatment of generalized anxiety disorder (GAD).
- Trial name
- NCT00475969
- Testing
- duloxetine
- Where
- United States
- Volunteers
- 327 people
- Sponsor
- Eli Lilly and Company
Anxiety Disorders
Duloxetine Compared With Placebo in Patients With Generalized Anxiety Disorder
This is a clinical trial assessing duloxetine compared with placebo in patients who have generalized anxiety disorder.
- Trial name
- NCT00122824
- Testing
- duloxetine hydrochloride
- Where
- 7 sites in United States, Finland and 5 more
- Volunteers
- 480 people
- Sponsor
- Eli Lilly and Company
Inflammatory Bowel Diseases
Duloxetine in Inflammatory Bowel Diseases
This open-label, prospective, single-arm pilot study investigates the use of duloxetine, a central neuromodulator, for improving psychological distress and functional impairment in adults with inflammatory bowel disease (IBD).
- Trial name
- Duloxetine in (NCT07431606)
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Pennsylvania
Worry, Anxiety
Effects of Duloxetine on Pathological Worry in Patients With Generalized Anxiety Disorder: A fMRI Study
(1) to compare the differences of neural activation of pathological worry between pre-treatment GAD patients and normal subjects; (2) to measure the differences of brain activation on worry in GAD patients before and after…
- Trial name
- NCT00491348
- Testing
- duloxetine hydrochloride
- Where
- Taiwan
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Depression, Major Depressive Disorder
eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk
This pilot randomized controlled trial seeks: (1) to determine the preliminary efficacy of our modernized collaborative care intervention for depression in improving the diabetes risk markers of hemoglobin A1c and insulin…
- Conditions
- Depression, Major Depressive Disorder, Dysthymic Disorder, Depressive Symptoms
- Trial name
- NCT04437485
- Testing
- Good Days Ahead (GDA), Problem Solving Treatment in Primary Care (PST-PC), Antidepressant Medications
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Indiana University
Major Depressive Disorder, Fibromyalgia
Duloxetine Compassionate Use in Patients Who Have Completed a Previous Neuroscience Duloxetine Clinical Trial
The primary objective of this study is to provide duloxetine to investigators for the treatment of patients who have previously participated in neuroscience duloxetine clinical trials and for whom effective alternative therapy is…
- Conditions
- Major Depressive Disorder, Fibromyalgia, Diabetic Peripheral Neuropathic Pain, Generalized Anxiety Disorder
- Trial name
- NCT00071708
- Testing
- Duloxetine Hydrochloride
- Where
- 13 sites in Australia
- Sponsor
- Eli Lilly and Company
1. Major Depressive Disorder
Supplemental Transcranial Magnetic Stimulation (TMS) vs. Standard Medication Monotherapy for Treating Major Depression: An Exploratory Field Study
A. Introduction to the Problem This field experiment is intended to explore whether supplemental transcranial magnetic stimulation (TMS) is more effective than standard medication mono-therapy for the treatment of major…
- Trial name
- NCT01944657
- Testing
- Supplemental TMS, Standard Medication Monotherapy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sheppard Pratt Health System
Urinary Stress Incontinence
Biomechanical Effects of Duloxetine on Bladder and Sphincter Muscle Function in Women in Pure Genuine Stress Incontinence
Double-blind placebo-controlled study of the biomechanical effects of duloxetine compared with placebo in the treatment of women with pure genuine stress incontinence
- Trial name
- NCT00190567
- Testing
- duloxetine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Eli Lilly and Company
Neuropathy in Cacer Patien
Comparison of the Efficacy and Safety of Duloxetine Augmented With Gabapentin and Duloxetine Augmented With Amitriptyline vs Duloxetine Alone in Chemotherapy -Induced Neuropathy
This study aimed to elucidate the relationship between the Efficacy and Safety of Comparison of the Efficacy and Safety Duloxetine augmented with gabapentin and amitriptyline augmented with Duloxetine vs duloxetine alone in…
- Trial name
- NCT06091553
- Testing
- Duloxetine alone, Duloxetine augmented with gabapentin, Duloxetine augmented with amitriptyline (as combined therapy)
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Beni-Suef University
Panic Disorder
The Efficacy and Tolerability of Duloxetine for the Treatment of Panic Disorder
The purpose of this study is to determine whether duloxetine is effective in the treatment of panic disorder.
- Trial name
- NCT00438971
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Massachusetts General Hospital