Clinical trials: Blood sampling
Breast Cancer, Prostate Cancer
Enumeration and Functional Analysis of Circulating Tumor Cells for Homologous Recombination: a Prospective Single-center Study on Advanced/Metastatic Solid Tumors
The goal of this clinical trial is to is to evaluate whether a correlation exists between functional HR status/CTC enumeration in expanded CTCs measured before treatment initiation, and Progression Free Survival (PFS) under PARPi…
- Conditions
- Breast Cancer, Prostate Cancer, Pancreatic Cancer, Ovarian Cancer
- Trial name
- E-FACTOR (NCT07555600)
- Testing
- blood sampling, Tumor sampling
- Volunteers
- 300 people
- Sponsor
- Centre Leon Berard
Asthma, Atopy
Protection Against Allergy: Study in Rural Environment - Part IV
PASTURE is a birth cohort of children born to farm and non-farm women from rural areas across Europe. Five study centres Austria, Germany, Switzerland, France and Finland enrolled 1133 children (farmers in about half of the…
- Trial name
- PATURE IV (NCT02929277)
- Testing
- blood sampling, skin prick tests, assesment of atopic dermatitis, questionnaires
- Volunteers
- 131 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
COVID19
USZ BioResource COVID-19
Mono-centric. Blood sampling for biobank development, including linkage to patient data (resource for research on COVID19).
- Trial name
- NCT04414657
- Testing
- blood sampling for biobank
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Regina Grossmann
Exercise Induced Muscle Damage, Cryotherapy
Acute Cryotherapy on Musculoskeletal Function and Biomarkers
In 2020, Dubois and Esculier proposed a paradigm shift in the acute management of musculoskeletal injuries, advocating for the transition from the traditional PRICE protocol- Protect, Rest, Ice, Compression, Elevation-to the more…
- Trial name
- NCT07211412
- Testing
- Cryotherapy, Eccentric exercise-induced muscle damage
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Attention Deficit Hyperactivity Disorder (ADHD)
The Correlation Between Blood omega3 and ADHD
Attention deficit hyperactivity disorder (ADHD) is a major problem in children and adolescents. Clinical and biochemical evidence suggests that deficiencies of polyunsaturated fatty acids (PUFA) could be related to ADHD.
- Trial name
- NCT02391428
- Testing
- blood test, omega3 capsules
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ayelet Omer Armon
Surgery, Stomach Cancer
TRANScriptional Pathways Of Surgical Pain Modulated by Music Therapy Exposure (TRANSPOSE)
Participants may take part in this study if they are scheduled to undergo a surgery that meets the following: (1) traditional open surgery via laparotomy, (2) length of surgery >3 hours, and (3) curative-intent surgical resection…
- Conditions
- Surgery, Stomach Cancer, Pancreas Cancer, Bile Duct Cancer
- Trial name
- NCT07653594
- Testing
- Music-assisted relaxation and imagery (MARI)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Case Comprehensive Cancer Center
Gestational Diabetes, Obesity
Comparison of Visceral Adipokines Visfatin, Vaspin and Omentin Levels in Gestational Diabetes Mellitus Pregnant Women
The prevalence of maternal obesity is increasing rapidly worldwide and constitutes an important obstetric problem that increases mortality and morbidity in both mothers and infants.
- Conditions
- Gestational Diabetes, Obesity, Visceral Obesity
- Trial name
- NCT05463237
- Testing
- oral glucose tolerance test, Blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Siirt University
Obesity
Ghrelin Regulation and Structure: Effect of Diet Composition on Ghrelin
The purpose of this study is to learn more about how diet affects the hormone ghrelin. Ghrelin is made in the stomach and causes appetite to increase.
- Trial name
- NCT00694512
- Testing
- Low fat diet, High fat diet, MCT diet
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Atrial Fibrillation (AF), Atrial Fibrillation (Prevention of Stroke)
Stroke Risk Assessment and Markers of Blood Clotting in Patients With Newly Diagnosed Non-valvular Atrial Fibrillation (NVAF), Who Have Not Received Oral Anticoagulation Therapy (OAC-therapy) Prior to Inclusion
Background: Atrial fibrillation (AF) is the most common heart rhythm disorder worldwide. Globally, there are 37.5 million people with AF.
- Conditions
- Atrial Fibrillation (AF), Atrial Fibrillation (Prevention of Stroke), Atrial Fibrillation New Onset, Non Valvular Atrial Fibrillation
- Trial name
- BIO-AF (NCT06949319)
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Nedim Tojaga
Pancreatic Cancer, Adult, Hereditary Pancreatic Cancer
PREVENPANC Project: a Spanish Multicenter Study for Pancreatic Cancer Prevention
Background: Pancreatic cancer (PC) is an aggressive cancer with only a 7% 5-year survival rate, primarily due to late-stage diagnosis.
- Conditions
- Pancreatic Cancer, Adult, Hereditary Pancreatic Cancer, Familial Pancreatic Cancer
- Trial name
- PREVENPANC (NCT06760741)
- Testing
- Multigene panel, Other, miRNA measurement in blood
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Intrapartum Fetal Distress
Fetal Scalp Stimulation Versus Fetal Blood Sampling in Labour
Pregnant women have routine monitoring of the baby's heart rate when in labour. Women with complicated pregnancies require continuous monitoring using an electronic recorder called a CTG.
- Trial name
- FIRSST (NCT05306756)
- Testing
- Fetal Blood Sampling (FBS), digital Fetal Scalp Stimulation (dFSS)
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- University of Dublin, Trinity College
Rare Diseases, Genetic Predisposition to Disease
Genome-based Management of Patients in Precision Medicine (Ge-Med) Towards a Genomic Health Program
The GE-MED APPROACH project will enroll patients (n = appr. 12.000) with unclear molecular cause of the disease, suspected genetic cause of the disease without detailed molecular analysis like Whole Exome Sequencing (WES).
- Trial name
- GE-MED (NCT04760522)
- Testing
- WGS Diagnostic: Blood take for genetic diagnostic
- Where
- Germany
- Volunteers
- 12,000 people
- Sponsor
- University Hospital Tuebingen
End Tidal Carbon Dioxide of Patients Undergoing General Anesthesia
Comparison of End-tidal Carbon Dioxide (ETCO2) Measured by Transportable Capnometer (EMMATM) and the Arterial pCO2 in General Anesthesia
An end-tidal CO 2 monitor (capnometer) is used most often as a noninvasive substitute for PaCO2 in anesthesia, anesthetic recovery and intensive care.
- Trial name
- NCT02184728
- Testing
- End-tidal CO2(portable capnometer)
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Inje University
Premature Ejaculation
Primary Premature Ejaculation Genetics
The main objective of our study is to identify the first genetic etiology of primary Premature Ejaculation (PE). We will test and evaluate the existence of genetic determinism conferring susceptibility to a life-long syndrome…
- Trial name
- NCT02109302
- Testing
- Blood sample, Skin biopsy, Questionnaire
- Where
- 3 sites in France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Colorectal Cancer
Identification of New Diagnostic Protein Markers for Colorectal Cancer
The search for biochemical markers in patient's blood for non-invasive colorectal cancer diagnostic has not yielded satisfactory results to date.
- Trial name
- EXOSCOL01 (NCT04394572)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 80 people
- Sponsor
- CHU de Reims
Multiple Sclerosis
Efficacy of Cholecalciferol (Vitamin D3) for Delaying the Diagnosis of MS After a Clinically Isolated Syndrome
The main objective of this study is to evaluate the efficacy and tolerance of 2 years of treatment with cholecalciferol (vitamin D3) in patients with a clinically isolated syndrome at high risk for MS (CIS).
- Trial name
- D-Lay-MS (NCT01817166)
- Testing
- Vitamin D, Imaging, Lumbar puncture
- Where
- 33 sites in France, Martinique
- Volunteers
- 316 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Healthy Volunteers
Insulin Modulation of fMRI Connectivity in Healthy Adults
This study evaluates the effects of changing insulin levels on brain activity. Participants will complete functional magnetic resonance imaging (fMRI) scans during fasting conditions, then during an insulin infusion.
- Trial name
- NCT02982551
- Testing
- Insulin, Taste Task, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Neurological Pathology, Healthy Subjects
[18F]-F13640 as a New Brain Radiopharmaceutical
This clinical assay is designed to validate that [18F]F13640 as a radiotracer of 5-HT1A functional receptors. A first group of healthy subjects underwent a PET scan with arterial blood sampling to determine the kinetic model of…
- Trial name
- F13640 (NCT03347331)
- Testing
- [18F]F13640
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
School Age Children, Blood
The Effect of Dry Heat and Dry Cold Application on Blood Sampling in Children
The study was conducted as a parallel group randomized controlled in order to determine the effects of dry heat and dry cold application before blood collection in school-aged children (7-12 years old) on pain, anxiety and fear…
- Conditions
- School Age Children, Blood, Procedural Pain, Procedural Anxiety
- Trial name
- NCT05974319
- Testing
- Dry heat application, Dry cold application
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Saglik Bilimleri Universitesi
Myelodysplastic Syndromes
A Pilot, Open-Label Study of Luspatercept for Patients With Lower Risk Myelodysplastic Syndromes (MDS)
To learn if luspatercept is more effective in helping to reduce the number of blood transfusions needed by patients with LR-MDS.
- Trial name
- NCT06113302
- Testing
- Luspatercept
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- M.D. Anderson Cancer Center