Clinical trials: Best Practice
Muscle Weakness
Best Practice Using Rocuronium and Reversal With Neostigmine or Sugammadex
This is an estimation study, prospectively evaluating the incidence of postoperative residual neuromuscular blockade (PRNB) when a best practice protocol is implemented for a cohort of abdominal surgery and orthopedic surgery…
- Trial name
- NCT03543826
- Testing
- Protocol for rocuronium neuromuscular block
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- University of Washington
Diagnostic Errors
Reducing Diagnostic Errors in Primary Care Pediatrics (Project RedDE)
The proposal will focus on 3 specific, high-risk, pediatric ambulatory diagnostic errors each representing a unique dimension of diagnostic assessment: evaluation of symptoms, evaluation of signs and follow-up of diagnostic…
- Trial name
- NCT02798354
- Testing
- Quality Improvement Collaborative
- Where
- United States
- Volunteers
- 13,853 people
- Sponsor
- Montefiore Medical Center
Alcohol Use Disorder (AUD)
Records for Alcohol Care Enhancement
Unhealthy alcohol use (the spectrum from risky consumption through alcohol use disorder, AUD) is a leading cause of preventable death in the US (88,424 deaths annually costing $249 billion a year), and alcohol-related health…
- Trial name
- RACE (NCT05492942)
- Testing
- Best Practice Advisory (BPA) and Population Health Management (PHM), Best Practice Advisory (BPA) and Clinical Care Management (CCM), Best Practice Advisory (BPA) and Population Health Management (PHM) and Clinical Care Management (CCM)
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Sleep Habit, Good, Sleep Hygiene
Effects of Sleep Hygiene Education on Sleep Health in Community-Dwelling Older Adults
This will be a study looking at trying to change community-dwelling older adults' behavior in regard to good sleep hygiene practices.
- Conditions
- Sleep Habit, Good, Sleep Hygiene, Health Behavior
- Trial name
- NCT05483920
- Testing
- One-time educational video, One-time educational video plus automated text messaging
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Black Hills State University
Opioid-Related Disorders
Improving Health and Employment Outcomes Through Workplace Opioid Policies
Evaluate the feasibility of implementing workplace opioid guidelines in the construction trades; define and collect measures of implementation and efficacy.
- Trial name
- NCT05387408
- Testing
- Best Practice Health and Employment Opioid-related Policies
- Where
- United States
- Volunteers
- 4,939 people
- Sponsor
- Washington University School of Medicine
Breast Carcinoma, Radiation-Induced Dermatitis
Topical Keratin in Treating Radiation Dermatitis in Patients With Breast Cancer
This randomized pilot clinical trial studies how well topical keratin works in treating radiation dermatitis in patients with breast cancer.
- Trial name
- NCT03374995
- Testing
- Best Practice, Quality-of-Life Assessment, Topical Keratin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Wake Forest University Health Sciences
Breast Neoplasms
Effect of Trastuzumab on Disease Free Survival in Early Stage HER2-Negative Breast Cancer Patients With ERBB2 Expressing Disseminated Tumor Cells
This phase II trial studies the efficacy of trastuzumab treatment in breast cancer patients with stage II-III human epidermal growth factor receptor 2 (HER2)-negative tumors and HER2-expressing bone marrow disseminated tumor…
- Trial name
- NCT01779050
- Testing
- Doxorubicin, Trastuzumab, Cyclophosphamide
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Washington University School of Medicine
Ischemic Stroke
POSITIVE Stroke Clinical Trial
Primary Endpoint: The primary objective is to show that AIS patients, ineligible for or refractory to treatment with IV-tPA, with appropriate image selection, treated with mechanical thrombectomy within 6-12 hours of symptom…
- Trial name
- NCT01852201
- Testing
- Endovascular Mechanical Thrombectomy
- Where
- 20 sites in United States
- Volunteers
- 33 people
- Sponsor
- Medical University of South Carolina
Hearing Loss, Noise-Induced
Does Sound Conditioning Protect Against Temporary Hearing Damage
This research project will contribute to the research surrounding the effect on the ear after noise exposure. This ever-growing field of research has never been more applicable than now with the increase of recreational noise…
- Trial name
- NCT03878875
- Testing
- Session One Test Battery, Session Two Test Battery, Session Three Test Battery
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Smoking Cessation
An EPIC Based BPA to Enhance Quit Line Referral and Use
Smoking is the number one cause of preventable death in the United States. Given the magnitude of the problem, interventions aimed at promoting smoking cessation have the potential to make large changes in improving health…
- Trial name
- NCT03229356
- Testing
- Best Practices Advisory (BPA), BPA + Enhanced Education
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Malignant Neoplasm
Impact of Early Mobility on Post-Surgery Recovery in Patients Undergoing Oncologic Surgeries
This trial studies the impact of early mobility tracked with a 3-dimensional (3D) motion tracking technology (XSENS) on post-surgery recovery in patients undergoing oncologic surgeries.
- Trial name
- NCT04000581
- Testing
- Best Practice, Physical Activity, Questionnaire Administration
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Roswell Park Cancer Institute
Acute Decompensated Heart Failure
Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve Decongestion Management System (DMS)
The objective of this study is to prospectively compare decongestive therapy administered by the Reprieve DMS system to Optimal Diuretic Therapy (ODT) in the treatment of patients diagnosed with acute decompensated heart failure…
- Trial name
- FASTR (NCT05174312)
- Testing
- Reprieve Decongestion Management System, Diuretic
- Where
- 16 sites in United States
- Volunteers
- 100 people
- Sponsor
- Reprieve Cardiovascular, Inc
Hypercholesterolemia, Hypercholesterolemia, Familial
Evaluating the Efficacy of Pediatric Lipid Screening Alerts
The purpose of the study is to evaluate prospectively the impact of different system alerts on the prescription of lipid panels to pediatric Geisinger patients (9-11 years old), as per the now-universal guidelines.
- Conditions
- Hypercholesterolemia, Hypercholesterolemia, Familial, Hypercholesteremia in Children, Hyperlipidemia in Children
- Trial name
- NCT04118348
- Testing
- Best Practice Alert, Health Maintenance Topic
- Where
- United States
- Volunteers
- 13,340 people
- Sponsor
- Geisinger Clinic
Asthma
A Comparison of Symbicort® Single Inhaler Therapy and Conventional Best Practice for the Treatment of Persistent Asthma
The primary objective is to compare the efficacy of Symbicort Single inhaler Therapy with treatment according to conventional best practice in adult patients with persistent asthma.
- Trial name
- PASSION (NCT00628758)
- Testing
- Symbicort TBH - Turbuhaler, beta-II-agonist, inhale steroid
- Where
- 15 sites in Turkey (Türkiye)
- Volunteers
- 430 people
- Sponsor
- AstraZeneca
Tobacco Use
Tobacco Cessation Treatment Preferences Among Veteran Smokers
There are significant barriers to tobacco cessation treatment for patients and providers in specialty care clinical settings. Specialty providers cite several barriers to delivering evidence-based tobacco cessation care…
- Trial name
- MESH (NCT05277207)
- Testing
- Personalized Smoking Cessation Facilitation Meetings, Personalized Smoking Cessation Pharmacotherapy, Personalized Text Messaging Support
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8
Improving Patient-Centered Communication in Breast Cancer Through Patient and Provider Interventions
This trial studies the effectiveness of two interventions on patient reported outcomes of patient centered communication and decision making about breast cancer treatment.
- Conditions
- Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8
- Trial name
- SHARES (NCT04549571)
- Testing
- Decision Aid iCanDecide - ESE website, Decision Aid iCanDecide - S website, Therapeutic Conventional Surgery
- Where
- 27 sites in United States
- Volunteers
- 614 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Chronic Conditions, Multiple
ElderTree Via a Voice Activated Device for Managing Chronic Health Conditions (NHLBI)
Multiple chronic conditions (MCCs) are costly and pervasive among older adults. MCCs account for 90% of Medicare spending, and 65% of Medicare beneficiaries have 3 or more chronic conditions; 23% have 5 or more.
- Trial name
- NCT05240534
- Testing
- ET-Text (Laptop), ET-Voice (Smart System)
- Where
- United States
- Volunteers
- 502 people
- Sponsor
- University of Wisconsin, Madison
Attention Deficit/Hyperactivity Disorder, Inattention
Pilot Testing PREschooler Care, Community Resources, Advocacy, Referral, Education (PRE-CARE)
The goal of this proposed study is to pilot test a novel treatment model (PRE-CARE) addressing unmet social needs for families of preschool-age children with Attention Deficit/Hyperactivity Disorder (ADHD) symptoms.
- Trial name
- PRE-CARE (NCT04999982)
- Testing
- Screening, Resource Packet, Resource Navigation
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Hematopoietic and Lymphoid System Neoplasm, Locally Advanced Malignant Solid Neoplasm
Design and Testing of a Web-Based Tool for the Improvement of End-of-Life Planning in Patients With Advanced Cancer
This clinical trial examines a web-based tool, in partnership with Peacefully, Inc, designed to improve end-of-life planning among patients with advanced cancers.
- Conditions
- Hematopoietic and Lymphoid System Neoplasm, Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm
- Trial name
- NCT05564468
- Testing
- Best Practice, Internet-Based Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Fred Hutchinson Cancer Center
Diabetes Mellitus
Mobile Insulin Titration Intervention
The purpose of this pilot study is to determine whether text message (and phone) communication can be effectively utilized to adjust long-acting insulin, compared to standard practice.
- Trial name
- MITI (NCT01879579)
- Testing
- Mobile Insulin Titration Intervention
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- NYU Langone Health