Clinical trials: Best Practice
Malignant Neoplasm
Meditative Slow Breathing or Isha Kriya Meditation in Improving Cancer-Related Symptoms in Hospitalized Participants With Cancer
This trial studies how well meditative slow breathing or Isha Kriya meditation works in improving cancer-related symptoms in hospitalized participants with cancer.
- Trial name
- NCT03445572
- Testing
- Best Practice, Meditation Therapy, Questionnaire Administration
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- M.D. Anderson Cancer Center
Overweight, Obesity
Healthy Families Healthy Forces Study
U.S. Army Medical Research \& Materiel Command Telemedicine and Advanced Technology Research Center (TATRC) is sponsoring the HF2 (Healthy Families, Healthy Forces) Study.
- Trial name
- HF2 (NCT02348853)
- Testing
- Healthy Weight for Living (HWL), Current Best Practice (CBP)
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Tufts University
Cerebrovascular Accident, Chronic Obstructive Pulmonary Disease
Tocilizumab for the Treatment of Cytokine Release Syndrome in Patients With COVID-19 (SARS-CoV-2 Infection)
This phase III trial compares the effect of adding tocilizumab to standard of care versus standard of care alone in treating cytokine release syndrome (CRS) in patients with SARS-CoV-2 infection.
- Conditions
- Cerebrovascular Accident, Chronic Obstructive Pulmonary Disease, Chronic Renal Failure, Coronary Artery Disease
- Trial name
- NCT04361552
- Testing
- Best Practice, Tocilizumab
- Where
- United States
- Sponsor
- Emory University
Adolescent Idiopathic Scoliosis
The Effects of Scoliosis-Specific Exercises Before Surgery
The aim of this study is to investigate the effects of scoliosis-specific exercises in adolescent idiopathic scoliosis patients, who had surgical indication, on functional capacity, cosmetic deformity perception, quality of life…
- Trial name
- NCT04357561
- Testing
- Exercise group (Schroth best practice)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Marmara University
Graft-versus-host Disease Prevention
Fecal Transplant +/- Gut Decontamination in Preventing Acute Graft Versus Host Disease in Patients Given Broad-Spectrum Antibiotics
This phase II trial studies how well a fecal microbiota transplant with or without total gut decontamination works in preventing graft versus host disease in patients exposed to broad-spectrum antibiotics.
- Trial name
- NCT03862079
- Testing
- Best Practice, Fecal Microbiota Transplantation, Nystatin
- Where
- United States
- Sponsor
- M.D. Anderson Cancer Center
Head and Neck Carcinoma
Nestle Impact Advanced Recovery in Improving Surgery Recovery in Patients With Head and Neck Cancer
This randomized clinical trial studies how well Nestle Impact Advanced Recovery works in improving surgery recovery in patients with head and neck cancer.
- Trial name
- NCT03261180
- Testing
- Best Practice, Laboratory Biomarker Analysis, Nutritional Intervention
- Where
- United States
- Sponsor
- OHSU Knight Cancer Institute
Lung Cancer
A Study to Optimize Care for Lung Cancer Patients Undergoing Video-Assisted Thoracoscopic Surgery (VATS)
This is a research study for participants who have been diagnosed with lung cancer and are receiving VATS (Video Assisted Thoracoscopic Surgery) lobectomy or segmentectomy.
- Trial name
- NCT02502695
- Testing
- VATS-associated best practices
- Where
- 6 sites in United States
- Volunteers
- 173 people
- Sponsor
- Dana-Farber Cancer Institute
Arrhythmia
Trial of a Best-Practice Alert in the Electronic Medical Record to Reduce Unnecessary Telemetry Monitoring
This is a randomized trial of a best-practice alert delivered via the electronic medical record (Apex) to physicians on the Medicine service at UCSF Medical Center over a six month period.
- Trial name
- NCT02529176
- Testing
- Best-practice alert
- Volunteers
- 1,021 people
- Sponsor
- University of California, San Francisco
Hearing Loss
Early Auditory Referral in Primary Care
Busy Primary Care providers (PCPs) have complex practices with many competing demands, making it difficult to improve their HL identification rates.
- Trial name
- EAR-PC (NCT03004937)
- Testing
- Family Medicine Hearing Loss Best Practice Alert
- Where
- 10 sites in United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pancreatic Diseases, Pancreatic Neoplasms
POstopeRative Standardization of Care: THe Implementation of Best Practice After Pancreatic Resection
This Nationwide stepped-wedge cluster randomized trial is designed to evaluate if the implementation of a best practice algorithm for postoperative care results in a decrease in incidence of major complications and death after…
- Conditions
- Pancreatic Diseases, Pancreatic Neoplasms, Pancreatic Cancer, Pancreatitis
- Trial name
- PORSCH (NCT03400280)
- Testing
- Best practice algorithm for postoperative care
- Where
- 17 sites in Netherlands
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- St. Antonius Hospital
Acute Conditions in Intensive Care
Prevention of Critical Incidents Related to the Nursing With Patients in Intensive Care Units
The purpose of this study is to assess the effectiveness of a best practices nursing protocol in intensive care units on the occurrence of critical incidents compared to the common practices.
- Trial name
- PREVENIR (NCT02881645)
- Testing
- Best practices
- Where
- France
- Volunteers
- 59,400 people
- Sponsor
- Central Hospital, Nancy, France
Malignant Head and Neck Neoplasm
Expiratory Muscle Strength Training in Improving Bulbar Function and Quality of Life in Patients With Head and Neck Cancer
This randomized clinical trial studies how well expiratory muscle strength training works in improving bulbar function and quality of life in patients with head and neck cancer.
- Trial name
- NCT03175289
- Testing
- Best Practice, Educational Intervention, Exercise Intervention
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Chronic Pain
Blood Flow - an Underlying Mechanism Behind Clinical Improvements in Patients With Subacromial Pain Syndrome?
The purpose of this randomized clinical trial is two-fold. Firstly to see if patients suffering Subacromial Pain Syndrome can improve blood flow in the supraspinatus muscle in their shoulder, and secondly to investigate how…
- Trial name
- NCT02701465
- Testing
- Exercise: local high intensity interval exercise, Exercise: best clinical practice
- Where
- Norway
- Volunteers
- 24 people
- Sponsor
- Norwegian University of Science and Technology
Tobacco Use Treatment
Dentistry United to Extinguish Tobacco
System level strategies for implementing tobacco use treatment guidelines exist but are insufficiently put into practice, particularly in dental care settings.
- Trial name
- DUET (NCT01615237)
- Testing
- Audit and performance feedback (PF), Financial Incentive (P4P), Current Best Practices (CBP)
- Where
- 2 sites in United States
- Volunteers
- 3,207 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Newborn; Infection
Deploying POKE Within Intermountain Healthcare
To assess the impact of POKE on babies, the investigators will longitudinally track outcomes before and after implementation at Intermountain Healthcare's five NICUs.
- Trial name
- POKE (NCT03688607)
- Testing
- There will not be an intervention, rather the investigators will deploy best practices and track POKEs within the healthcare system to evaluate clinical and operational outcomes.
- Where
- United States
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- Intermountain Health Care, Inc.
Anxiety, No Evidence of Disease
Video-Based Intervention in Reducing Anxiety in Patients Undergoing Lung Cancer Screening
This pilot trial studies a video-based intervention in reducing anxiety in patients undergoing lung cancer screening. Giving a video-based intervention to patients prior to lung cancer screening may reduce anxiety and improve the…
- Conditions
- Anxiety, No Evidence of Disease, Lung Carcinoma
- Trial name
- NCT02288416
- Testing
- educational intervention, questionnaire administration, quality-of-life assessment
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Acute Myeloid Leukemia
Gluten Free Diet in Diminishing Side Effects Patients With Acute Myeloid Leukemia Undergoing Induction Chemotherapy
This randomized phase II trial studies how well a gluten free diet works in diminishing side effects in patients with acute myeloid leukemia undergoing induction chemotherapy.
- Trial name
- NCT03108911
- Testing
- Best Practice, Biospecimen Collection, Dietary Intervention
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Rutgers, The State University of New Jersey
Tropical Infectious Diseases
Optimizing Sysmex Technology as an Innovative Tool to Differentiate Between Malaria (PALUdism) and BACterial Infections in a Malaria Endemic Region
Severe malaria and bacterial Blood Stream Infections (bBSI) are impossible to differentiate clinically. This poses a particular threat in low resource areas, where bBSI is often not diagnosed due to the unavailability of rapid…
- Trial name
- PALUBAC (NCT02669823)
- Testing
- None, treatment as actual best practice
- Where
- Burkina Faso
- Volunteers
- 930 people
- Sponsor
- Sysmex Europe GmbH
Leg Ulcers
Safety Evaluation of Biatain Ibu in Painful Chronic Venous Leg Ulcers
The objective of this open label extension study (extension to study DK143WS) is to evaluate the safety of Biatain Ibu during 6 -12 weeks of exposure and during a 40 - 46 weeks safety follow-up period.
- Trial name
- NCT00628004
- Testing
- Biatain Ibu, Local best practice
- Where
- 5 sites in Denmark, Germany and 1 more
- Volunteers
- 93 people
- Sponsor
- Coloplast A/S
Smoking Cessation
Smoking Cessation for American Indians
American Indians and Alaska Natives (AI/ANs) have the highest smoking rates of the major racial/ethnic groups in the United States, approaching 40% to 50%.1-3 In addition, this underserved population has very low smoking…
- Trial name
- NCT01106456
- Testing
- All Nations Breath of Life (ANBL), Nontailored program (NT), Pharmacotherapy
- Where
- 2 sites in United States
- Volunteers
- 463 people, healthy volunteers welcome
- Sponsor
- Won Choi, PhD, MPH