Clinical trials: Best Practice
Dysplastic Nevus, Health Status Unknown
Internet-based Intervention for Skin Self-Examination in Participants With Increased Risk for Melanoma
This trial studies an internet-based intervention for skin self-examination (SSE) in participants at increased risk for melanoma. Early detection of suspicious growths on the skin can be done by performing regular SSE checks.
- Conditions
- Dysplastic Nevus, Health Status Unknown, Melanoma, No Evidence of Disease
- Trial name
- NCT03725449
- Testing
- Best Practice, mySmartCheck, Survey Administration
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Heart Failure, Heart Failure With Reduced Ejection Fraction
Building Electronic Tools To Enhance and Reinforce Cardiovascular Recommendations - Heart Failure
This is a feasibility study using a cross-over design to implement and compare a best practice alert (BPA) with an automated in-basket message to inform providers when a patient with heart failure and reduced ejection fraction…
- Trial name
- BETTER CARE-HF (NCT05077293)
- Testing
- Best Practice Alert (BPA), In-Basket Message
- Where
- United States
- Volunteers
- 596 people
- Sponsor
- NYU Langone Health
Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma
Financial Navigation Intervention in Improving Financial and Clinical Outcomes in Patients With Newly Diagnosed Gastric or Gastroesophageal Junction Adenocarcinoma
This trial studies how well a financial navigation intervention works in improving financial and clinical outcomes in patients with newly diagnosed gastric or gastroesophageal junction adenocarcinoma.
- Trial name
- NCT03986502
- Testing
- Media Intervention, Informational Intervention, Best Practice
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Pancreatic Cancer, Locally Advanced Pancreatic Adenocarcinoma
PREOPANC-4 Implementation Program for Locally Advanced Pancreatic Cancer
A prospective, nationwide, implementation program of the international standard of excellence for locally advanced pancreatic cancer (LAPC) care in the Netherlands (2021[7]-2030[6]), including a multidisciplinary training program…
- Conditions
- Pancreatic Cancer, Locally Advanced Pancreatic Adenocarcinoma, Pancreatic Adenocarcinoma Non-resectable, Chemotherapy Effect
- Trial name
- PREOPANC-4 (NCT05524090)
- Testing
- Implementation - International best-practice care
- Where
- Netherlands
- Volunteers
- 223 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Health Status Unknown
Art in Improving Outcomes in Participants Undergo Surgery
This trial studies how well art works in improving outcomes in participants who are undergoing surgery. Exposure to art may help to improve clinical and psychological outcomes.
- Trial name
- NCT03688945
- Testing
- Art Therapy, Best Practice, Questionnaire Administration
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Roswell Park Cancer Institute
Malignant Neoplasm
Impact of Early Mobility on Post-Surgery Recovery in Patients Undergoing Oncologic Surgeries
This trial studies the impact of early mobility tracked with a 3-dimensional (3D) motion tracking technology (XSENS) on post-surgery recovery in patients undergoing oncologic surgeries.
- Trial name
- NCT04000581
- Testing
- Best Practice, Physical Activity, Questionnaire Administration
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Roswell Park Cancer Institute
Breast Carcinoma, Colorectal Carcinoma
Incorporating ePrognosis for the Encouragement of Smarter Screening for Breast and Colorectal Cancer in Older Adults
This clinical trial assesses the feasibility and acceptability of a smarter screening intervention for breast and colorectal cancer in older adults.
- Trial name
- NCT05021172
- Testing
- Best Practice, Informational Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Advanced Breast Adenocarcinoma, Advanced HER2-Negative Breast Carcinoma
Effects of Ribociclib and Palbociclib on Tumor and Blood Characteristics in Patients With Metastatic Breast Cancer
This clinical trial attempts to understand the differences between two chemotherapy drugs, ribociclib and palbociclib, and how they fight cancer.
- Conditions
- Advanced Breast Adenocarcinoma, Advanced HER2-Negative Breast Carcinoma, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8
- Trial name
- NCT05244434
- Testing
- Best Practice, Biopsy, Biospecimen Collection
- Sponsor
- City of Hope Medical Center
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Acupuncture in Reducing Chemotherapy-Induced Peripheral Neuropathy in Participants With Stage I-III Breast Cancer
The goal of this study is to obtain preliminary evidence of the effect of 8 acupuncture treatments over 10 weeks in breast and GI cancer patients who are currently receiving or recently completed active neurotoxic chemotherapy…
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- NCT03505671
- Testing
- Acupuncture Therapy, Best Practice, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Wake Forest University Health Sciences
Penicillin Allergy
Effect of Providing Stratification of Low Risk Penicillin Allergies on Penicillin Allergy Label Removal in ICU Setting
Currently it is estimated that at least 25 million people in the United States are labeled as penicillin allergic although less than 1.5 million of these are truly allergic.
- Trial name
- NCT03702283
- Testing
- Penicillin Allergic Risk Stratification Best Practice Alert
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Malignant Abdominal Neoplasm, Malignant Head and Neck Neoplasm
Digital and Behavioral Tele-Health Tapering Program for Lowering Dependence on Opioids in Patients Undergoing Surgery
This clinical trial studies the effect of behavioral health support including tele-health in helping surgical patients taper off of prescription opioid pain medications.
- Conditions
- Malignant Abdominal Neoplasm, Malignant Head and Neck Neoplasm, Malignant Solid Neoplasm, Malignant Thoracic Neoplasm
- Trial name
- NCT04963972
- Testing
- Behavioral Intervention, Best Practice, Questionnaire Administration
- Where
- United States
- Volunteers
- 272 people
- Sponsor
- Lucid Lane, Inc
Major Depressive Disorder
Comparative Effectiveness of Pharmacogenomics for Treatment of Depression
The overall goal of this study is to assess the effectiveness of a widely available and widely used combinatorial pharmacogenomic (PGx) test for the treatment of major depressive disorder.
- Trial name
- CEPIO-D (NCT03749629)
- Testing
- GeneSight Psychotropic test, Canadian Network for Mood and Anxiety Treatment (CANMAT) Best Practice Guidelines
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Massachusetts General Hospital
Bone Diseases, Communication
Evaluation of Alerts in Promoting Bone Densitometry Scans
The purpose of this study is to assess, prospectively, the effect of provider-facing alerts for bone densitometry scans with and without a single-click best practice alert (BPA) on scan orders and completions.
- Trial name
- NCT04955652
- Testing
- Health Maintenance Topic, Actionable Sidebar Item, Best Practice Alert
- Volunteers
- healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Neuropathy
Home-Based Neurofeedback Program in Treating Participants With Chemotherapy-Induced Peripheral Neuropathy
This trial studies how well a home-based neurofeedback program works in treating participants with chemotherapy-induced peripheral neuropathy (nerve damage that affects motor function).
- Trial name
- NCT03436680
- Testing
- Best Practice, Neurofeedback, Quality-of-Life Assessment
- Sponsor
- M.D. Anderson Cancer Center
Plasma Cell Myeloma
Fermented Milk Supplementation on Symptoms of Disease and Treatment in Patients With Multiple Myeloma
This trial investigates the effect of fermented milk supplementation on symptoms of disease and treatment in patients with multiple myeloma.
- Trial name
- NCT04530812
- Testing
- Best Practice, Kefir, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Roswell Park Cancer Institute
Diabetes, Foot Ulcer
Preventing Amputations by Tailored Risk-based Intervention to Optimize Therapy
The PATRIOT study will evaluate a risk-based personalized behavioral intervention to improve foot self-care, self-monitoring, and modifiable risks for amputation such as blood glucose, blood pressure and cholesterol in order to…
- Trial name
- PATRIOT (NCT02356757)
- Testing
- Personalized Behavioral Intervention, Current Best Practice
- Where
- United States
- Volunteers
- 406 people
- Sponsor
- VA Office of Research and Development
Wounds
Cold Plasma Jet kINPen Med Versus Best Practice Wound Dressings
Within the treatment of chronic wounds the main objective is to analyze the wound healing properties with cold plasma (cold plasma jet kINPen® Med) compared to wound phase-adapted best practice wound dressings.
- Trial name
- NCT04965805
- Testing
- cold plasmaJet kINPen Med, Best practice wound dressings
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Federal University Teaching Hospital, Feldkirch, Austria
Spinal Cord Injury, Sleep-disordered Breathing
Treatment of Sleep-disordered Breathing in Patients With SCI
Sleep-disordered breathing (SDB) remains under-treated in individuals living with spinal cord injuries and disorders (SCI/D). The investigators' aim is to test a program that addresses challenges and barriers to positive airway…
- Conditions
- Spinal Cord Injury, Sleep-disordered Breathing, Spinal Cord Disease, Multiple Sclerosis
- Trial name
- NCT02830074
- Testing
- Best practices PAP + patient Education +ongoing Support and Training, Sleep Education
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- VA Office of Research and Development
Hearing Loss
Aging, Cognition, and Hearing Evaluation in Elders Study
The investigators will conduct a small pilot study that will randomize ~ 40 70-84 year-old adults with hearing loss to best-practices hearing rehabilitative treatment (hearing assessment, counseling, fitting of amplification…
- Trial name
- ACHIEVE-P (NCT02412254)
- Testing
- Best practices hearing rehabilitative treatment, Successful aging intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cancer Survivor, Central Obesity
Physical Activity in Reducing Metabolic Dysregulation (MetD) in Obese Latina Breast Cancer Survivors
This randomized phase II trial studies how well physical activity works in reducing metabolic dysregulation in obese Latina breast cancer survivors.
- Conditions
- Cancer Survivor, Central Obesity, No Evidence of Disease
- Trial name
- NCT03120390
- Testing
- Best Practice, Exercise Intervention, Laboratory Biomarker Analysis
- Where
- United States
- Sponsor
- University of Southern California