Clinical trials: Best Practice
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
A Collaborative Intervention for Improving Cancer Pain Management in Cancer Survivors
This clinical trial tests a collaborative pain management intervention (ASCENT) for improving cancer pain in cancer survivors. Cancer pain is prevalent, under-treated, and remains a major cause of suffering, impairment, and…
- Conditions
- Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm
- Trial name
- ASCENT (NCT06198010)
- Testing
- Best Practice, Educational Intervention, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 680 people
- Sponsor
- Mayo Clinic
Attention Deficit/Hyperactivity Disorder, Inattention
Pilot Testing PREschooler Care, Community Resources, Advocacy, Referral, Education (PRE-CARE)
The goal of this proposed study is to pilot test a novel treatment model (PRE-CARE) addressing unmet social needs for families of preschool-age children with Attention Deficit/Hyperactivity Disorder (ADHD) symptoms.
- Trial name
- PRE-CARE (NCT04999982)
- Testing
- Screening, Resource Packet, Resource Navigation
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Recurrent Prostate Carcinoma
Multicenter Randomized Trial of 68Ga-PSMA-11 PET/CT Based SRT After Radical Prostatectomy
This phase III trial studies how well Gallium Ga 68-labeled PSMA-11 (68Ga-PSMA-11) positron emission tomography (PET)/computed tomography (CT) works in diagnosing participants with prostate cancer that has come back after…
- Trial name
- PSMA SRT (NCT03582774)
- Testing
- Best Practice, Computed Tomography, Gallium Ga 68-labeled PSMA-11
- Where
- 2 sites in United States
- Volunteers
- 193 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Chronic Low-back Pain
The BEST Trial: Biomarkers for Evaluating Spine Treatments
The BEST Trial (Biomarkers for Evaluating Spine Treatments) is a National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)-sponsored clinical trial being conducted through the NIH Helping to End Addiction…
- Trial name
- BEST (NCT05396014)
- Testing
- Enhanced Self-Care (ESC), Acceptance and Commitment Therapy (ACT), Evidence-Based Exercise and Manual Therapy (EBEM)
- Where
- 12 sites in United States
- Volunteers
- 1,014 people
- Sponsor
- University of North Carolina, Chapel Hill
Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia
Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia
This phase III trial compares the effect of xylitol dental wipes to dental wipes without xylitol for the reduction of bloodstream infection in children with acute myeloid leukemia (AML).
- Trial name
- NCT07022678
- Testing
- Best Practice, Biospecimen Collection, Cytarabine
- Where
- 39 sites in United States
- Volunteers
- 556 people
- Sponsor
- Children's Oncology Group
PTSD, Depression
The Effect of BAT Versus Mixed Physical Activity as add-on Treatment for Traumatised Refugees.
The aim of this randomised controlled trial is to study two types of physical activities as add-on treatment, compared to treatment as usual for traumatised refugees.
- Conditions
- PTSD, Depression, Pain
- Trial name
- PTF4 (NCT01955538)
- Testing
- Control, Basic Body Awareness Therapy, Mixed physical activity
- Where
- Denmark
- Volunteers
- 338 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Cancer
Decision Making for Older Adults With Cancer
This is a minimal risk, pilot cluster randomized controlled trial (CRT) to determine the feasibility and acceptability of training medical oncologists to use the Best Case/Worst Case-Geriatric Oncology (BC/WC-GeriOnc)…
- Trial name
- NCT05374304
- Testing
- Best Case/Worst Case (BC/WC) Geriatric Oncology (GeriOnc) communication tool
- Where
- 3 sites in United States
- Volunteers
- 65 people
- Sponsor
- University of California, San Francisco
Tuberculosis
Whole Genome Sequencing of Tuberculosis for Disease Control in Madagascar
Tuberculosis (TB) whole genome sequencing (WGS) allows outbreak identification and disease transmission tracking. It is hypothesized that prospective WGS-guided epidemiological investigations improve case detection compared to…
- Trial name
- TB_WGS_cRCT (NCT05406453)
- Testing
- Whole Genome Sequencing testing
- Where
- Madagascar
- Volunteers
- 98,362 people
- Sponsor
- Institut Pasteur de Madagascar
Nursing Students, Education Program on Dementia
Enhancing Healthcare Students' Attitudes Toward Dementia Care Through Virtual Reality Education
This quasi-experimental study focuses on Indonesian nursing students and aims to examine the effectiveness of virtual reality (VR) dementia educational programs. The study addresses the following research questions: 1.
- Trial name
- NCT06629844
- Testing
- The VR dementia education group, The control group
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitas Airlangga
Bowel Preparation Quality
Can Artificial Intelligence Reduce Consumption of Standard High Volume Bowel Preparation Regimen Among Older Population, Without Compromising the Quality of Colonoscopy? An International Multi-centre Randomized Controlled Trial.
The goal of this study is to assess the clinical and cost-effectiveness of the AI bowel preparation evaluation system in reducing the consumption volume of the standard high-volume PEG regimen before colonoscopy among the older…
- Trial name
- AIBP (NCT06904209)
- Testing
- AI
- Where
- Hong Kong
- Volunteers
- 1,824 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Nutrition Intervention, Quality Improvement
Optimizing Early Nutrition Management of Extremely and/or Very Preterm Infants
A clinical quality improvement bundle on early nutrition supplementation is developed to improving the clinical outcomes (including growth, organ function, and neurodevelopment outcomes) of extremely and/or very preterm infants.
- Conditions
- Nutrition Intervention, Quality Improvement, Preterm Infant
- Trial name
- NCT07538999
- Testing
- A nutritional improving bundle for the intervention group, Routine nutritional strategies for the control group
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Fudan University
Duchenne Muscular Dystrophy
Sleep Intervention in Young Boys with Duchenne Muscular Dystrophy
This project will systematically plan and evaluate the implementation of the Transdiagnostic Sleep and Circadian Intervention for youth (TranS-CY).
- Trial name
- DMD (NCT04529707)
- Testing
- Transdiagnostic Behavioral Sleep Intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Pittsburgh
Patient Activation, Mobilization
Evaluation of the Effect of Robot-assisted Early Mobilization - Project MobiStaR
Within the MobiStaR project the adaptation of procedures in an intensive care unit combined with the use of this robotic system will create the conditions to increase the mobilization rate of critically ill intensive care…
- Conditions
- Patient Activation, Mobilization, Robotics
- Trial name
- MobiStaR (NCT05071248)
- Testing
- VEMO (Reactive Robotics GmbH)
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Stroke, Acute, Ischemic Stroke, Acute
Hospital Implementation of a Stroke Protocol for Emergency Evaluation and Disposition
Most stroke patients are initially evaluated at the closest hospital but some need to be transferred to a hospital that can provide more advanced care.
- Conditions
- Stroke, Acute, Ischemic Stroke, Acute, Hemorrhagic Stroke
- Trial name
- HI-SPEED (NCT06094478)
- Testing
- HI-SPEED Protocol
- Where
- 8 sites in United States
- Volunteers
- 900 people
- Sponsor
- University of Chicago
Motor Vehicle Injury
Swivel Convertible Child Safety Seat to Improve Usage
Child car safety seats (or "car seats") are an important tool to keep children safe in motor vehicle crashes, but are often misused by parents and caregivers. The installation of car seats can be time consuming and confusing.
- Trial name
- NCT06866171
- Testing
- Modular child restraint
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Minnesota HealthSolutions
Prostate Cancer, mCRPC
A Phase 3 Study of [177Lu]Ludotadipep for Metastatic Castration-Resistant Prostate Cancer
Primary Efficacy Endpoint Radiographic Progression-Free Survival (rPFS): rPFS is defined as the time from randomization to radiographic disease progression (PD), as assessed by Blinded Independent Central Review (BICR) according…
- Trial name
- NCT07853209
- Testing
- [177-Lu]Ludotadipep, Best supportive care/standard of care (BSC/SOC) alone
- Where
- 8 sites in South Korea
- Volunteers
- 114 people
- Sponsor
- FutureChem
Chronic Kidney Diseases
Survey on Anemia Therapy in Participants With Chronic Kidney Disease (CKD) Not on Dialysis
This study is a prospective, non-interventional, cross-sectional multicenter survey. The aim is to better understand the current therapy pattern for anemia in CKD treated with erythropoiesis-stimulating agents (ESAs) and not…
- Trial name
- NCT02238067
- Testing
- ESA, Satisfaction Survey Questionnaire
- Where
- 7 sites in Israel
- Volunteers
- 196 people
- Sponsor
- Hoffmann-La Roche
Hiv, Insomnia
HIV-related Insomnia and Inflammation
This randomized trial will determine the effects of internet cognitive behavioral therapy on measures of systemic inflammation in HIV-positive people receiving antiretroviral therapy.
- Trial name
- NCT04721067
- Testing
- SHUTi, Sleep Education/Hygiene
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Indiana University
Respiratory Failure, Multiple Organ Failure
Prevention of Severe Acute Respiratory Failure in Patients With PROOFCheck
Severe acute respiratory failure (ARF) requiring prolonged mechanical ventilation is the most common form of acute organ dysfunction in the hospital, and is often associated with multiple organ failure (MOF), high mortality, and…
- Trial name
- PROOFcheck (NCT02488174)
- Testing
- PROOFcheck, Standard Care
- Where
- 3 sites in United States
- Volunteers
- 34,040 people
- Sponsor
- Albert Einstein College of Medicine
Chronic Low Back Pain
Efficacy of Classification Based 'Cognitive Functional Therapy' in Patients With Non Specific Chronic Low Back Pain
A randomized controlled trial of the efficacy of classification based cognitive functional physiotherapy according to the system proposed by Peter O'Sullivan as compared to manual therapy and exercise in patients with non…
- Trial name
- NCT01129817
- Testing
- Cognitive Functional Therapy, Manual therapy and exercise
- Where
- Norway
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Bergen