Clinical trials: Best Practice
Atrial Fibrillation
Atrial Fibrillation (AF) and Electrocardiogram (EKG) Interpretation Project ECHO
The goal of this study is to determine the effectiveness of a direct-to-provider virtual education program ("AF and EKG Interpretation Project ECHO") for primary care providers who manage patients with atrial fibrillation (AF).
- Trial name
- NCT05890274
- Testing
- AF and EKG Interpretation Project ECHO
- Where
- 3 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Stenoses, Dyspnea
Endoscopic Treatment
The placement of an endoprosthesis in the airways leads to rapid and dramatic clinical improvement in the majority of cases of central airway obstruction.
- Trial name
- ETNA (NCT07727824)
- Testing
- Informed consent, Eligibility criteria check, Randomisation
- Where
- 6 sites in France
- Volunteers
- 96 people
- Sponsor
- University Hospital, Toulouse
Glycaemic Index, Glycaemic Response
Establishing the Glycaemic Index of Vegetable Smoothies
Glycaemic responses to carbohydrates ingested as fruit and vegetables may vary depending on factors inherent to the fruit or vegetable, and on the type of sugar.
- Conditions
- Glycaemic Index, Glycaemic Response, Glycaemic Response Measurements
- Trial name
- VEG-GI (NCT07729631)
- Testing
- Vegetable Smoothie
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Bath
Schizophrenia, Schizophrenia Spectrum Disorder
tDCS and Executive Function Training for Schizophrenia
Schizophrenia-spectrum disorders are the most persistent, debilitating, and economically burdensome mental illnesses worldwide. Cognitive remediation (CR) is a psychological intervention based on principles of learning and…
- Conditions
- Schizophrenia, Schizophrenia Spectrum Disorder, Schizophrenia and Related Disorders
- Trial name
- NCT05389345
- Testing
- Transcranial direct current stimulation, Executive function training
- Where
- Canada
- Sponsor
- University of Toronto
Multiple Sclerosis (MS), Fatigue
Increasing Physical Activity for Adults With Multiple Sclerosis (MS)
This study aims to advance the scientific understanding and potential future implementation of physical activity promotion by testing the efficacy of a phone-based app for increasing activity in insufficiently active patients…
- Conditions
- Multiple Sclerosis (MS), Fatigue, Physical Inactivity
- Trial name
- NCT06270641
- Testing
- ExerciseRx intervention
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Washington
Rectal Prolapse
Breakthrough Improvement Collaborative for Ventral Mesh Rectopexy
Different studies showed large variation between care processes in multiple diseases, this leads to large variation in outcomes.
- Trial name
- BIC4VMR (NCT05728554)
- Testing
- Learning session 1, Learning session 2, Learning session 3
- Where
- Belgium
- Volunteers
- 320 people
- Sponsor
- KU Leuven
Metastatic Pancreatic Adenocarcinoma
Safety and Effectiveness Study of CPI-613 and/or Gemcitabine to Treat Metastatic Pancreatic Cancer
This Phase II study is conducted to assess the safety and efficacy of CPI-613 in patients with metastatic pancreatic cancer. The primary outcome measure is Overall Survival (OS).
- Trial name
- NCT01830322
- Testing
- CPI-613, Gemcitabine, Any non-gemcitabine chemotherapies or best supportive care
- Where
- 2 sites in United States
- Sponsor
- Cornerstone Pharmaceuticals
Pain, Obesity, Childhood
Sumamos Excelencia Project: Implementation of Best Practices in Clinical Practice (Thrid Edition)
There is a gap between research and clinical practice, leading to variability in decision-making. Multifaceted implementation strategies are for improving implementation of best practices.
- Conditions
- Pain, Obesity, Childhood, Breast Feeding, Incontinence, Urinary
- Trial name
- SE24 (NCT06522529)
- Testing
- Multifaceted implementation strategy
- Where
- Spain
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Instituto de Salud Carlos III
Clinical Stage II HPV-Mediated (p16-pos) Oropharyngeal Carcinoma, Clinical Stage III HPV-Mediated (p16-pos) Oropharyngeal Carcinoma
A Pneumatic Compression Device for the Treatment of Lymphedema in Patients With Stage II-IV Head and Neck Cancer After Chemoradiation
This clinical trial tests whether adding the use of a pneumatic compression system with manual lymphatic drainage versus manual lymphatic drainage alone in treating patients with lymphedema after chemoradiation for stage II-IV…
- Conditions
- Clinical Stage II HPV-Mediated (p16-pos) Oropharyngeal Carcinoma, Clinical Stage III HPV-Mediated (p16-pos) Oropharyngeal Carcinoma, Clinical Stage IV HPV-Mediated (p16-pos)Oropharyngeal Carcinoma, Head and Neck Carcinoma
- Trial name
- NCT05512767
- Testing
- Best Practice, Consensus Auditory-Perceptual Evaluation of Voice, Diagnostic Imaging
- Sponsor
- Mayo Clinic
Depression
Comparison Study of Family Practice Interventions for Depression in Adults
To determine if treatment of significant depressive symptoms identified in individuals attending a family practice improves either psychiatric outcome, overall health care costs, or Quality of Life (QOL).
- Trial name
- NCT01975207
- Testing
- Treatment as usual, Internet Intervention, Depression Treatment Pathway
- Volunteers
- 1,489 people, healthy volunteers welcome
- Sponsor
- AHS Cancer Control Alberta
Asthma
SYMPHONIE - A Comparison of Symbicort Single Inhaler and Conventional Best Practice for the Treatment of Persistent Asthma in Adolescents and Adults
The purpose of the study is to compare the efficacy of a flexible dose of Symbicort with conventional stepwise treatment according to asthma treatment guidelines in patients with persistent asthma.
- Trial name
- NCT00259792
- Testing
- Budesonide/formoterol Turbuhaler
- Where
- 82 sites in France
- Volunteers
- 1,000 people
- Sponsor
- AstraZeneca
HIV, Heart Failure
Proof-of-concept of a Behavioral Intervention to Improve the Cardiovascular Health of People Living With HIV
Heart failure (HF) is a growing health and economic burden around the globe, and it remains a leading cause of morbidity and mortality among the general population.
- Trial name
- HEICA-HIV-2025 (NCT07105007)
- Testing
- Exercise Intervention, Tailored Education sessions, Behavioral coaching
- Where
- 2 sites in United States, Brazil
- Volunteers
- 30 people
- Sponsor
- University of Washington
COVID-19
COVID-19 Antithrombotic Rivaroxaban Evaluation
There are several ways in which the COVID-19 pandemic may affect the prevention and management of thrombotic and thromboembolic disease, either direct effect or the indirect effects of infection, such as through severe illness…
- Trial name
- CARE (NCT04757857)
- Testing
- Rivaroxaban 10 mg
- Where
- 36 sites in Brazil
- Volunteers
- 660 people
- Sponsor
- Hospital Alemão Oswaldo Cruz
Breast Carcinoma
Mobile-Health Delivery of Lifestyle Interventions for Women With Breast Cancer
This clinical trial aims to develop a lifestyle program to improve clinical outcomes in women with breast cancer who do not have a healthy diet, regular exercise habits, or ways to manage their stress well.
- Trial name
- NCT05132296
- Testing
- Behavioral Intervention, Best Practice, FitBit
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Low Back Pain, Neck Pain
Stratified Targeted Engagement From Primary Care to Physical Therapy (STEPPT)
The goal of this clinical trial is to learn if a health system intervention called "Stratified Targeted Engagement from Primary Care to Physical Therapy (STEPPT)" can improve how often doctors refer Hispanic patients with spine…
- Trial name
- STEPPT (NCT07290361)
- Testing
- Engagement of clinic leadership (System Intervention - Usual Care), Engagement of clinic leadership (System Intervention - STEPPT), Patient Registry (System Intervention - STEPPT)
- Where
- United States
- Volunteers
- 17,587 people
- Sponsor
- San Diego State University
Eczema
Barrier Enhancement for Eczema Prevention
The primary objective is to determine whether advising parents to apply emollient (moisturiser) to their child's skin for the first year of life in addition to best practice infant skin care advice can prevent or delay the onset…
- Trial name
- BEEP (NCT04680520)
- Testing
- Experimental (Doublebase Gel® or Diprobase Cream®), Best practice skin care advice booklet
- Where
- 16 sites in United Kingdom
- Volunteers
- 1,394 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia
Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia
This phase III trial compares the effect of xylitol dental wipes to dental wipes without xylitol for the reduction of bloodstream infection in children with acute myeloid leukemia (AML).
- Trial name
- NCT07022678
- Testing
- Best Practice, Biospecimen Collection, Cytarabine
- Where
- 39 sites in United States
- Volunteers
- 556 people
- Sponsor
- Children's Oncology Group
Stroke
Clinical Pathways for Effective and Appropriate Care
The purposes of this study are to determine whether clinical pathways: 1)improve the quality of the care provided to patients affected by stroke in terms of clinical outcomes, efficiency continuity of care and patients'…
- Trial name
- NCT00673491
- Testing
- Clinical Pathways
- Volunteers
- 448 people
- Sponsor
- Agenzia Regionale Sanitaria delle Marche
Lyme Disease
Perceptions,Social Representations and Experience of Lyme Borreliosis and Ticks in Adolescents Likely to be Infected and Their Parents
the study is offered to adolescents aged 12 to 17 and their families suspected of or suffering from Lyme barilliosis. During inclusion, three interviews will be carried out for each family.
- Trial name
- ADO-LY (NCT05678478)
- Testing
- semi-directed interview concerning the experience of adolescents and their parents on Lyme borreliosis and on the tick.
- Where
- 2 sites in France
- Volunteers
- 5 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Cardiovascular Diseases
The Global cVAD Study
The intent of the Global cVAD Study is to utilize observational data of the ABIOMED, Inc. hemodynamic support devices in real-world settings to drive best practice usage patterns identified through study analysis, to serve as a…
- Trial name
- cVAD (NCT04136392)
- Testing
- ABIOMED, Inc. hemodynamic support devices
- Where
- 51 sites in United States
- Volunteers
- 20,000 people
- Sponsor
- Abiomed Inc.